Core Viewpoint - The Hong Kong pharmaceutical sector is experiencing a strong performance, driven by the rise of the National Index for Hong Kong Innovative Drugs, with leading stocks such as BeiGene, InnoCare Pharma, and 3SBio showing significant gains [1] Group 1: Market Performance - The Hong Kong Innovative Drug ETF (159567) opened higher and rose over 3% by 9:50 AM, with a trading volume exceeding 600 million yuan, indicating a slight increase compared to the previous day [1] - The strong performance of the index has positively influenced the trading activity of popular ETFs in the market [1] Group 2: Investment Outlook - CITIC Securities released a report forecasting the investment trends in the pharmaceutical sector through 2026, highlighting the concentration of innovation among Chinese pharmaceutical companies and supportive policies for innovative drugs and medical devices [1] - The healthcare industry is expected to gradually return to a market pricing system driven by clinical value and demand, leading to a stable and sustainable domestic pharmaceutical market environment [1] - Listed companies in the sector are anticipated to experience continuous and stable earnings growth, contributing to a positive growth outlook for the industry [1] Group 3: Investment Opportunities - The Hong Kong Innovative Drug ETF (159567) tracks the National Index for Hong Kong Innovative Drugs, aiming to reflect the operational characteristics of listed companies in the innovative drug sector within the Hong Kong Stock Connect [1] - Investors can also access the Hong Kong Innovative Drug ETF through connecting funds, providing an opportunity to capitalize on the upward potential of the innovative drug sector [1]

Core Insights - After the earnings announcement, BeiGene's A-shares rose over 6% to 312.99 CNY, while H-shares increased over 7% to 228.8 HKD, reaching the highest level since November 2021 [1] Financial Performance - For Q3 2025, the company reported revenue of 10.077 billion CNY, a year-on-year increase of 41.1% [1] - The net profit attributable to shareholders was 689 million CNY, marking a turnaround from a loss to profit [1] - For the first three quarters, total revenue reached 27.595 billion CNY, up 44.2% year-on-year [1] - The net profit attributable to shareholders for the first three quarters was 1.139 billion CNY, also indicating a turnaround from a loss to profit [1] Operational Efficiency - The significant changes in performance were primarily driven by increased product revenue and improved operational efficiency due to effective cost management [1]

11月13日早盘，港股整体回调，"创新药一哥"百济神州继续领跑，带动创新药板块逆市走强！截至发 稿，百济神州涨超7%续创三年新高，信达生物、三生制药续涨超5%，创新药含量100%的港股通创新药 ETF（520880）逆市冲高3%！ | | | 分时 · 6日 1分 5分 15分 30分 · | | | | | | F9 盘航盘后 婴加 九弦 面述 工具 @ (2) > | | | | | 通販通创新的ETF (1) | 31. | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | | | | | 520880(税配通省新商ET) 09:50 � 0.580 通跌 0.015(2.65%) 均价 0.575 服交量 1. .. | | | | 100 3,1096 | | 0.580 +0.015 +2.65% | | | × 520880 | | 0.577 [ VM P | | | | | | | | | 2.00% | | SSE CNY 9:50:28 交易中 | ...

Group 1 - The core viewpoint highlights the active performance of innovative drug concept stocks, with notable movements in specific companies [1] - Nanjing Xinbai has achieved two consecutive trading limits, indicating strong investor interest [1] - BeiGene has seen an increase of over 6%, reflecting positive market sentiment towards its stock [1] Group 2 - Other companies such as Hainan Hai Chen Pharmaceutical, Lianhua Technology, Wanze Shares, and Xinlitai have also experienced upward trends, suggesting a broader rally in the sector [1]

Core Viewpoint - The Hong Kong stock market's biopharmaceutical sector experienced a significant rally, with notable gains from companies such as BeiGene, which rose over 6%, along with other firms like Tigermed and CanSino Biologics also seeing increases [1] Group 1 - The biopharmaceutical sector in Hong Kong is showing positive momentum, indicating investor confidence and potential growth opportunities [1] - BeiGene's stock price increased by more than 6%, highlighting its strong market performance [1] - Other companies in the sector, including Tigermed and CanSino Biologics, also experienced upward movement, suggesting a broader trend within the industry [1]

Core Viewpoint - The stocks of several biotechnology companies, including BeiGene, WuXi AppTec, and Legend Biotech, have experienced notable increases in their share prices, indicating positive market sentiment towards these companies [1] Group 1 - BeiGene (06160.HK) shares rose by 6.59% [1] - WuXi AppTec (02126.HK) shares increased by 3.97% [1] - Legend Biotech (02105.HK) shares went up by 3.33% [1]

Core Insights - BeiGene's stock rose over 6% following the release of its Q3 2025 earnings report, with a current price of HKD 224.2 and a trading volume of HKD 239 million [1] Financial Performance - The company reported a revenue of RMB 27.595 billion for the first three quarters of 2025, representing a year-on-year growth of 44.2% [1] - Net profit attributable to shareholders was RMB 1.139 billion, marking a turnaround from a loss to profit [1] - Basic earnings per share stood at RMB 0.81 [1] Product Revenue Breakdown - Global revenue for Zebrutinib (BTK) reached USD 1.04 billion in Q3 2025, showing a year-on-year increase of 50.8% and a quarter-on-quarter increase of 9.6% [2] - Revenue from Zebrutinib in the U.S. was USD 740 million (up 46.7% year-on-year, up 8.0% quarter-on-quarter) [2] - European revenue for Zebrutinib was USD 160 million (up 67.7% year-on-year, up 8.4% quarter-on-quarter) [2] - Revenue from Zebrutinib in China was USD 90 million (up 36.3% year-on-year, up 11.1% quarter-on-quarter) [2] - The company anticipates a 5-10% quarter-on-quarter growth for Zebrutinib in Q4 2025, with global revenue expected to exceed USD 3.9 billion for the year [2] - Global revenue for Tislelizumab (PD-1) was USD 190 million, reflecting a year-on-year growth of 16.7% [2] Future Projections - Haitong International has revised its revenue forecasts for BeiGene for FY25-27 to USD 5.3 billion, USD 6.4 billion, and USD 7.1 billion respectively, indicating a three-year revenue CAGR of 23% [1] - The net profit forecasts for FY25-27 have also been adjusted to USD 360 million, USD 660 million, and USD 1.05 billion respectively, reflecting better-than-expected growth in sales and R&D expenses [1]

Core Insights - On November 12, BeiGene's stock rose by 5.62%, with a trading volume of 1.793 billion yuan [1] - As of November 12, BeiGene's total margin trading balance reached 1.332 billion yuan, indicating a high level of trading activity [1] Financing Summary - On November 12, BeiGene had a financing buy-in amount of 201 million yuan, while the financing repayment was 231 million yuan, resulting in a net financing outflow of 30.15 million yuan [1] - The current financing balance of 1.312 billion yuan accounts for 3.88% of the circulating market value, which is above the 90th percentile level over the past year [1] Securities Lending Summary - On November 12, BeiGene repaid 1,200 shares in securities lending and sold 2,015 shares, amounting to a selling value of 591,600 yuan based on the closing price [1] - The remaining securities lending balance is 66,600 shares, with a total value of 19.56 million yuan, also exceeding the 90th percentile level over the past year [1] Company Overview - BeiGene, established on October 28, 2010, and listed on December 15, 2021, is located in the Zhongguancun Life Science Park, Beijing [1] - The company's main business involves the research, development, production, and commercialization of innovative drugs, with 99.10% of revenue coming from drug sales and 0.90% from collaboration arrangements [1] Shareholder Information - As of September 30, the number of BeiGene shareholders increased by 55.33% to 36,200, while the average circulating shares per person decreased by 35.79% to 3,195 shares [2] - For the period from January to September 2025, BeiGene reported a revenue of 27.595 billion yuan, a year-on-year increase of 44.21%, and a net profit attributable to shareholders of 1.139 billion yuan, up 130.88% year-on-year [2] Institutional Holdings - As of September 30, among the top ten circulating shareholders, China Europe Medical Health Mixed A ranked fourth with 4.6788 million shares, a decrease of 146,600 shares from the previous period [2] - Hong Kong Central Clearing Limited entered as a new shareholder, holding 3.1565 million shares, while other notable changes included a significant reduction in holdings by several funds [2]

Core Viewpoint - The company plans to increase funding for its drug clinical trial research project using remaining raised funds and extend the project's implementation period until December 31, 2026 [17][26]. Group 1: Financial Data - The adjusted operating profit for the first three quarters of 2025 is 5.543 billion yuan, compared to 52 million yuan in the same period last year [6]. - The adjusted net profit for the first three quarters of 2025 is 4.729 billion yuan, compared to a net loss of 474 million yuan in the same period last year [6]. - The net cash flow from operating activities, after deducting capital expenditures, is 3.200 billion yuan, compared to -4.797 billion yuan in the same period last year [6]. Group 2: Fundraising and Investment - The company raised a total of 2.216 billion yuan from its initial public offering, with a net amount of 2.163 billion yuan after deducting issuance costs [19]. - The company intends to use 163.155 million yuan of the remaining raised funds to increase investment in the drug clinical trial research project [18][22]. - The project includes various stages of drug development, such as preclinical and clinical research, and aims to enhance the company's innovative drug development capabilities [21][24]. Group 3: Project Implementation and Timeline - The implementation period for the drug clinical trial research project will be extended to December 31, 2026, to accommodate the increased funding and project needs [26]. - The company emphasizes the necessity and feasibility of increasing funding for the project to maintain its competitive edge in innovative drug development [24][25]. - The project will be closely monitored to ensure efficient use of funds and timely completion [27].

Major Events - Hong Kong Stock Exchange (00388) plans to make a strategic investment in Xunqing Settlement Holdings Limited [1] - Lai Kai Pharmaceutical-B (02105) signs an exclusive licensing agreement with Qilu Pharmaceutical for LAE 002 (AFURESERTIB) in China [1] - TECHSTARACQ-Z (07855) is expected to inherit the company Tuda Tong's listing on the main board of the Stock Exchange on December 10 [1] - Superstar Legend (06683) intends to establish a joint venture with Yushu Technology to develop consumer-grade IP robots and IP derivative products [1] - Beijing Enterprises Holdings (00392) plans to acquire 100% equity of Beijing Beiran Special Equipment Inspection and Testing Co., Ltd. for 54.6 million yuan [1] - CSPC Pharmaceutical Group (01093) has its application for the marketing of Pertuzumab Injection accepted by the National Medical Products Administration [1] - Rongli Construction (09639) plans to collaborate with CATL to develop efficient energy storage systems and solutions [1] Operating Performance - BeiGene (06160) reports a net profit attributable to shareholders of 1.139 billion yuan for the first three quarters, turning from loss to profit year-on-year [1] - Tencent Music-SW (01698) reports a net profit attributable to equity holders of 2.15 billion yuan in the third quarter, a year-on-year increase of 36.0% [1] - Zhou Li Fu (06168) sees a 32% year-on-year increase in e-commerce revenue for the first ten months, with net profit rising 71% year-on-year [1] - China Resources Land (01109) reports a cumulative contract sales amount of approximately 169.6 billion yuan for the first ten months, a year-on-year decrease of 16.6% [1]