格隆汇8月4日｜药明康德公告称，截至2025年7月31日，公司累计通过集中竞价交易方式回购A股股份 6514425股，占公司本公告日总股本的0.2268%，回购最高价格人民币90.70元/股，回购最低价格人民币 65.53元/股，使用资金总额人民币4.97亿元。 ...

Investment Rating - The report maintains an "Outperform" rating for the pharmaceutical and biotechnology sector [5][4]. Core Insights - The pharmaceutical sector has shown stronger performance compared to the overall market, with a 2.95% increase in the biopharmaceutical sector while the total A-share market declined by 1.01% [28]. - The report highlights significant advancements in Alzheimer's disease treatments presented at the 2025 AAIC conference, including promising data from various clinical trials [11][25]. - The current price-to-earnings (P/E) ratio for the pharmaceutical sector is 39.10x, which is at the 80.69th percentile of its historical valuation over the past five years [33]. Summary by Sections Market Performance - The overall A-share market decreased by 1.01%, with the Shanghai Composite Index down 1.75% and the ChiNext Index down 0.74%. In contrast, the biopharmaceutical sector increased by 2.95% [28]. - Within the biopharmaceutical sector, chemical pharmaceuticals rose by 5.01%, while medical devices saw a slight decline of 0.07% [28]. Clinical Research Updates - Roche's Trontinemab, a new generation Aβ antibody, demonstrated a 91% clearance rate of Aβ plaques in high-dose groups during Phase 1b/2a trials, with a low incidence of ARIA-E side effects [2][17]. - The report emphasizes the strategic focus of international pharmaceutical companies on Alzheimer's treatments, with FDA approvals for Biogen/Easai's Lecanemab and Lilly's Donanemab [25]. Company Earnings Forecasts - Major companies in the sector, such as Mindray Medical and WuXi AppTec, are projected to maintain strong earnings growth, with P/E ratios expected to decrease over the next few years [4]. - Mindray Medical is highlighted for its robust international expansion and product upgrades, while WuXi AppTec is noted for its comprehensive drug development services [37][38]. Recommended Stocks - The report recommends several companies, including Mindray Medical, WuXi AppTec, and Aier Eye Hospital, citing their strong market positions and growth potential in the pharmaceutical and medical services sectors [37][38].

智通财经APP讯，药明康德(02359)发布公告，于2025年8月4日该公司斥资人民币2799.43万元回购30.74 万股A股，回购价格为每股人民币89.95-92.56元。 ...

格隆汇8月4日丨药明康德(02359.HK)发布公告，2025年8月4日耗资2799.43万元人民币回购30.74万股A 股，回购价格每股89.95-92.56元。 ...

证券之星消息，8月4日医疗服务板块较上一交易日下跌0.26%，昭衍新药领跌。当日上证指数报收于 3583.31，上涨0.66%。深证成指报收于11041.56，上涨0.46%。医疗服务板块个股涨跌见下表： | 代码 | 名称 | 收盘价 | 涨跌幅 | 成交量(手) | | 成交额(元) | | --- | --- | --- | --- | --- | --- | --- | | 688265 | 南模生物 | 43.73 | 20.01% | | 4.08万 | 1.66亿 | | 688621 | 阳光诺和 | 66.54 | 14.84% | | 12.60万 | 8.15亿 | | 301201 | 诚达药业 | 28.10 | 4.04% | | 10.58万 | 2.93亿 | | 688222 | 成都先导 | 24.74 | 3.82% | | 33.55万 | 7.91亿 | | 002172 | 澳洋健康 | 4.25 | 3.41% | | 70.07万 | 2.93亿 | | 688046 | 药康生物 | 16.41 | 3.01% | | 4.55万 | 7293.23万 | | ...

FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 公司名稱： 無錫藥明康德新藥開發股份有限公司 呈交日期： 2025年8月4日 如上市發行人的已發行股份或庫存股份出現變動而須根據《香港聯合交易所有限公司（「香港聯交所」）證券上市規則》(「《主板上市規則》」)第13.25A條 / 《香港聯合交易所有限公司GEM證券 上市規則》(「《GEM上市規則》」)第17.27A條作出披露，必須填妥第一章節 。 | 第一章節 | | | | | | | | --- | --- | --- | --- | --- | --- | --- | | 1. 股份分類 | 普通股 | 股份類別 A | | 於香港聯交所上市 | 否 | | | 證券代號 (如上市) | | 說明 | 於上海證券交易所上市 | | | | | A. 已發行股份或庫存股份變動 | | | | | | | | | | 已發行股份（不包括庫存股份）變動 | | 庫存股份變動 | | | | | 事件 | 已發行股份（不包括庫存股份）數 目 | 佔有關事件前的現有已發 行股份（不包括庫存股 份）數目百分比 ...

呈交日期: 2025年8月4日 I. 法定/註冊股本變動 截至月份: 2025年7月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 無錫藥明康德新藥開發股份有限公司 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 備註： 第 1 頁 共 12 頁 v 1.1.1 FF301 FF301 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02359 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 387,076,150 | RMB | | 1 RMB | | 387,076,150 | | 增加 / 減少 (-) | | | 0 | | | RMB | | 0 | | 本月底結存 | | | 387,076,150 | RMB | | 1 RMB | | 387,0 ...

Group 1 - The core viewpoint of the article highlights the strong performance of WuXi AppTec (603259)(02359) in the first half of the year, with robust growth in revenue and net profit, as well as an expansion in profit margins [1] - The TIDES business segment has shown outstanding performance, while the chemical business has demonstrated resilient growth, helping to offset the weakness in clinical CRO and testing services [1] - The management has raised the revenue guidance for 2025 to between 42.5 billion and 43.5 billion RMB, indicating a projected growth of 13% to 17% in ongoing operations, with capital expenditures remaining unchanged at 7 billion to 8 billion RMB [1] Group 2 - According to the report, the profit forecasts for WuXi AppTec for the next two years have been increased by 15% and 22% respectively [1] - The target price for the company has been raised from 81 HKD to 122 HKD, while maintaining a "Buy" rating [1]

Core Viewpoint - WuXi AppTec (02359) demonstrated strong performance in the first half of the year, with robust growth in revenue and net profit, alongside margin expansion and notable performance in TIDES business [1] Financial Performance - Revenue and net profit showed steady growth, with TIDES business performing exceptionally well [1] - The chemical business exhibited resilient growth, helping to offset the weakness in clinical CRO and testing services [1] Management Guidance - Management raised the 2025 revenue guidance to RMB 42.5 billion to RMB 43.5 billion, indicating a projected growth of 13% to 17% in ongoing operations [1] - Capital expenditure remains unchanged at RMB 7 billion to RMB 8 billion [1] Analyst Forecasts - Zhongyin International upgraded WuXi AppTec's earnings forecasts for the next two years by 15% and 22% respectively [1] - The target price was increased from HKD 81 to HKD 122, maintaining a "Buy" rating [1]

Investment Rating - The investment rating for the CXO industry is "Outperform the Market" [1] Core Insights - The CXO index has increased by over 50% in the past year due to the easing of geopolitical risks, recovery in investment, and the digestion of high pandemic baselines [2] - Chinese CXO companies are analyzed from short-term, medium-term, and long-term perspectives to understand their global competitiveness [2] - Major players in the large molecule CDMO sector include WuXi Biologics and WuXi AppTec, with over 70% of their revenue coming from overseas [2] - The small molecule CDMO sector shows strong recovery in domestic companies, with significant order growth and a favorable competitive landscape [2] - Clinical and preclinical CROs are currently in an adjustment phase, with domestic order prices stabilizing but showing no significant recovery [2] Summary by Sections Large Molecule CDMO - Short-term performance shows high growth with competition from Japan, South Korea, and Europe [2] - Medium-term order growth is led by South Korean companies like Samsung Biologics, indicating intense competition for Chinese firms [2] - Long-term capital expenditures remain high, reflecting confidence in future demand [2] Small Molecule CDMO - Domestic companies are recovering from pandemic-related performance dips, with overall growth expected in 2025 [2] - Order growth is robust, with WuXi AppTec's orders increasing by 47% year-on-year by the end of 2024 [2] - Long-term capital expenditures show divergence, with some leaders like WuXi AppTec expected to continue increasing investments [2] Clinical/Preclinical CRO - Both domestic and international CROs are in an adjustment period, with 2022-2023 investment cooling reflected in 2024 performance [2] - Medium-term order volumes and values are beginning to show growth, while international orders remain stable [2] - Long-term capital expenditures vary among companies, indicating potential supply-demand mismatches in the short term [2] Emerging Business Opportunities - Rapid development in new molecular businesses such as peptides and oligonucleotides is expected to open up growth opportunities in the CXO sector [3] - Generic drug CROs are actively pursuing innovative transformations to seek new growth points [3]