Group 1 - Huaneng Power announced that its shareholder Hunan Energy Group plans to reduce its stake by up to 20.31 million shares, not exceeding 1% of the total share capital [1] - Ankai Bus reported a production of 1,012 buses in August, a year-on-year increase of 68.06%, with sales of 773 buses, up 46.95% year-on-year [1] - Lianhuan Pharmaceutical received a drug registration certificate for Famotidine injection, classified as a Class 3 chemical drug [1][2] Group 2 - Dongrui Co. reported sales of 94,800 pigs in August, generating revenue of 160 million yuan, a month-on-month decrease of 5.48% [3] - Tiancheng Control's subsidiary received a notification for a passenger car seat assembly project, expected to start production in April 2026 [5] - ST Huluwa obtained a drug registration certificate for Cefodizime capsules, a third-generation broad-spectrum cephalosporin [6] Group 3 - Jiulong Biotech announced the resignation of its Vice Chairman and General Manager Liang Hongjun due to work adjustments [8] - Guanhua High-tech's shareholder plans to reduce its stake by up to 17.50 million shares, not exceeding 1% of the total share capital [9] - Hebei Steel received approval to issue bonds totaling up to 10 billion yuan [10] Group 4 - Yunnan Energy Investment's subsidiaries received a total of 309 million yuan in renewable energy price subsidies [12] - Zhenghong Technology reported sales of 16,800 pigs in August, with a revenue of 22.87 million yuan, showing a year-on-year increase in sales volume of 63.31% [14] - Jilin Aodong's subsidiary received a drug registration certificate for a solution used in asthma treatment [16] Group 5 - Aonong Biological reported a 26.84% year-on-year increase in pig sales volume in August, reaching 150,100 pigs [18] - Xingdesheng announced a share repurchase plan with a budget of 15 to 30 million yuan [20] - Yueyang Lin Paper's Chairman Ye Meng resigned due to work adjustments [22] Group 6 - Kangchen Pharmaceutical's controlling shareholder plans to reduce its stake by up to 4.78 million shares, not exceeding 3% of the total share capital [23] - Changchun Yidong's General Manager Liu Xiaodong resigned due to work adjustments [25] - Zhongzai Resources' subsidiary received a government subsidy of 12.75 million yuan [26] Group 7 - Tianyu Biological reported a 41.89% month-on-month increase in sales revenue from pig sales in August [27] - Changfei Optical's shareholder Draka Comteq B.V. reduced its stake from 10% to 5% [27] - Zhongchuan Technology's Chairman Wu Xingwang resigned due to work adjustments [28] Group 8 - Huakang Clean announced a successful bid for a medical service construction project valued at 131 million yuan [29] - Yuegui Co. plans to establish a wholly-owned subsidiary with a registered capital of 100 million yuan [31] - Baisheng Intelligent's Vice General Manager and Board Secretary Huang Lijun resigned for personal reasons [32] Group 9 - Jiangsu Shuntian will change its stock name to "Suhao Fashion" starting September 10, 2025 [34] - Jiahe Meikang's shareholder plans to reduce its stake by up to 1.3759 million shares, not exceeding 1% of the total share capital [35] - Heng Rui Pharmaceutical received approval for clinical trials of HRS-4729 injection [37] Group 10 - Changfei Optical's shareholder plans to reduce its stake by up to 110,000 shares, not exceeding 0.15% of the total share capital [39] - Yutong Bus reported sales of 4,260 vehicles in August, a year-on-year increase of 16.78% [40] - JinkoSolar received 646 million yuan in renewable energy subsidies in August, a 248% increase year-on-year [41] Group 11 - Beijing Lier signed a strategic cooperation agreement with SenseTime and Xiwang Technology for AI collaboration [43] - Gongdong Medical's controlling shareholder plans to reduce its stake by up to 3% [44] - Zhonghuan Hailu terminated its control change plan and resumed trading [46] Group 12 - Longzi Co. reported a tax payment of 22.27 million yuan due to a tax audit [48] - Guoguang Chain's controlling shareholder plans to reduce its stake by up to 2.99% [49] - Guoxin Technology successfully tested a new high-performance chip for automotive electronics [50] Group 13 - GF Securities reported a cumulative increase in borrowings exceeding 20% of its net assets [51] - China Construction Bank's subsidiary plans to increase capital by 3 billion yuan [52] - Jifeng Technology plans to establish a wholly-owned subsidiary with a capital of 50 million yuan [53] Group 14 - Jiantou Energy received approval for a stock issuance plan to specific investors [54] - Shanghai Laishi's executives plan to collectively increase their holdings by at least 6 million yuan [55] - Wencan Co. reported a fire incident at its subsidiary, with no casualties reported [56]

Core Viewpoint - ST HuLuWa (605199.SH) has received the drug registration certificate for Cefdinir capsules from the National Medical Products Administration, marking a significant milestone in its product development [1] Group 1: Product Development - Cefdinir is classified as a third-generation broad-spectrum cephalosporin antibiotic, effective against various infections sensitive to Cefdinir [1] - The company has invested a total of 4.4957 million yuan in the research and development of this product [1]

Core Viewpoint - ST HuLuWa (605199.SH) has received the drug registration certificate for Cefdinir capsules from the National Medical Products Administration, indicating a significant regulatory approval for the company’s product line [1] Company Summary - The approved drug, Cefdinir, is a third-generation broad-spectrum cephalosporin antibiotic, effective against various bacterial strains including Staphylococcus, Streptococcus, and Escherichia coli [1] - Cefdinir is indicated for treating multiple infections such as pharyngitis, tonsillitis, acute bronchitis, pneumonia, otitis media, and urinary tract infections among others [1] - The approval signifies that the drug meets the technical requirements for quality and efficacy consistent with reference formulations, and it is considered to have passed the consistency evaluation for generic drug quality and efficacy [1] Industry Summary - The approval of Cefdinir aligns with the growing demand for effective antibiotics in the healthcare sector, particularly for treating bacterial infections [1] - The regulatory approval process highlights the importance of compliance with quality standards in the pharmaceutical industry, which can impact market competitiveness [1]

Core Viewpoint - ST HuLuWa (605199.SH) has received the drug registration certificate for Cefdinir capsules from the National Medical Products Administration, indicating a significant regulatory approval for the company’s product line [1] Group 1: Product Information - Cefdinir is a third-generation broad-spectrum cephalosporin antibiotic [1] - The drug is indicated for infections caused by various bacteria, including Staphylococcus, Streptococcus, and Escherichia coli, among others [1] - Specific infections treated by Cefdinir include pharyngitis, tonsillitis, acute bronchitis, pneumonia, otitis media, sinusitis, pyelonephritis, cystitis, and several skin and soft tissue infections [1]

证券代码：605199 证券简称：ST 葫芦娃 公告编号：2025-066 海南葫芦娃药业集团股份有限公司 关于获得头孢地尼胶囊药品注册证书的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 海南葫芦娃药业集团股份有限公司（以下简称"公司"）近日收到国家药品监督 管理局（以下简称"国家药监局"）核准签发的关于头孢地尼胶囊的《药品注册证 书》。现将有关情况公告如下： 上市许可持有人：海南葫芦娃药业集团股份有限公司 受理号：CYHS2302701 药品批准文号：国药准字 H20255295 审批结论：根据《中华人民共和国药品管理法》及有关规定，经审查，本品符 合药品注册的有关要求，批准注册，发给药品注册证书。质量标准、说明书、标签 及生产工艺照所附执行。药品生产企业应当符合药品生产质量管理规范要求方可生 产销售。 二、药品研发及相关 一、药品基本情况 药物名称：头孢地尼胶囊 剂型：胶囊剂 注册分类：化学药品 4 类 规格：0.1g 三、投资风险 公司高度重视药品研发，并严格控制药品研发、制造及销售环节的质量及安全。 上述药品获 ...

Core Viewpoint - ST HuLuWa (605199.SH) has received the drug registration certificate for Cefdinir capsules from the National Medical Products Administration, indicating a significant regulatory approval for the company’s product line [1] Company Summary - The newly approved Cefdinir is a third-generation broad-spectrum cephalosporin antibiotic, effective against various bacterial strains including Staphylococcus, Streptococcus, and Escherichia coli [1] - The drug is indicated for treating multiple infections such as pharyngitis, tonsillitis, acute bronchitis, pneumonia, otitis media, and urinary tract infections among others [1] - The approval was granted based on the drug meeting the technical requirements for quality and efficacy consistent with reference formulations, which also implies passing the consistency evaluation for generic drugs [1] Industry Summary - The approval of Cefdinir capsules reflects the ongoing regulatory support for antibiotic development in the pharmaceutical industry, particularly for broad-spectrum antibiotics [1] - The market for antibiotics is critical, given the rising concerns over antibiotic resistance and the need for effective treatments for bacterial infections [1]

Core Viewpoint - ST HuLuWa Pharmaceutical, once known as "China's top children's medicine brand," is currently facing severe challenges, with significant declines in revenue and profit reported in its 2025 semi-annual report [2][3]. Financial Performance - In the first half of 2025, ST HuLuWa achieved operating revenue of 508 million yuan, a year-on-year decrease of 42.89% [2]. - The net profit attributable to shareholders was 2.41 million yuan, down 94.14% year-on-year, while the net profit after deducting non-recurring gains and losses turned into a loss of 18.78 million yuan, a decline of 514.52% [2]. - The decline in performance is attributed to market demand fluctuations and intensified industry competition, particularly in the sales of respiratory medications [2]. Core Business Challenges - The core business segment of ST HuLuWa has experienced a severe downturn, with respiratory medications generating revenue of 299 million yuan, accounting for 58.86% of total revenue but down 52.91% year-on-year [3]. - Digestive system medications generated 109 million yuan, representing 21.46% of revenue, while systemic anti-infection medications brought in 49.51 million yuan, making up 9.74% of revenue [3]. Expense Structure - Sales expenses decreased significantly to 107 million yuan, down 60.25% year-on-year, accounting for 21.06% of revenue [4]. - Financial expenses increased to 21.07 million yuan, a rise of 77.74% year-on-year, primarily due to interest expenses from loan capitalized after project completion [4]. - R&D expenses were drastically reduced to 19.38 million yuan, down 80.69% year-on-year, attributed to the confirmation of R&D expenses based on progress [4]. Asset Quality - As of June 30, 2025, ST HuLuWa had cash and cash equivalents of 169 million yuan, a decrease of 33.65% from the end of 2024, mainly due to reduced cash receipts from sales [4]. - Accounts receivable increased to 455 million yuan, up 19.71% from the beginning of the period, with longer collection cycles due to the "two-invoice system" policy [5]. Regulatory Issues - ST HuLuWa faces serious challenges beyond performance declines, including issues with financial credibility and internal control deficiencies [6]. - In March 2025, the Hainan Securities Regulatory Bureau issued administrative measures against ST HuLuWa for non-compliance in revenue recognition and pricing, leading to significant adjustments in previously reported profits [6]. - The company adjusted its net profit for 2023 and the first half of 2024 by approximately 95.64 million yuan and 37.66 million yuan, respectively, revealing that much of the previously reported profit was not from genuine business activities [6]. Audit Concerns - In April 2025, the accounting firm Li Xin issued a qualified opinion on ST HuLuWa's 2024 financial report and a negative opinion on its internal control audit [6]. - The audit revealed that the controlling shareholder provided funds to customers through non-employee personal accounts, raising concerns about the collectability of large accounts receivable [6]. - ST HuLuWa purchased eight R&D projects from an affiliated company for 42.05 million yuan, which has ties to the actual controller, raising questions about the commercial rationale and potential financial impact of these transactions [7].

Core Viewpoint - Hainan Huluwa Pharmaceutical Group Co., Ltd. (referred to as "Huluwa Pharmaceutical") reported a significant decline in revenue and profit for the first half of 2025, primarily due to reduced sales of respiratory medications [1][2]. Financial Performance - The company's revenue for the first half of 2025 was 508 million yuan, a year-on-year decrease of 42.89% [1]. - The net profit attributable to shareholders was 2.41 million yuan, down 94.14% year-on-year [1]. - The net profit after deducting non-recurring items was -18.78 million yuan, a decline of 514.52% year-on-year [1]. - Revenue from respiratory medications was 299 million yuan, accounting for 58.86% of total revenue, with a year-on-year decline of 52.91% [2]. - Revenue from digestive system medications was 109 million yuan, making up 21.46% of total revenue [2]. - Revenue from systemic anti-infection medications was 49.51 million yuan, representing 9.74% of total revenue [2]. Cost Structure - Sales expenses decreased significantly to 107 million yuan, down 60.25% year-on-year, accounting for 21.06% of revenue [2]. - Financial expenses increased to 21.07 million yuan, a rise of 77.74% year-on-year, primarily due to interest expenses from loans after project completion [2]. - Research and development expenses fell to 19.38 million yuan, down 80.69% year-on-year [3]. Balance Sheet and Liquidity - The company's cash and cash equivalents decreased to 169 million yuan, a reduction of 33.46% from the end of 2024 [4]. - Accounts receivable increased to 455 million yuan, a growth of 19.71% from the beginning of the period [4]. - The asset-liability ratio reached 74.33%, indicating a high level of debt relative to assets [4]. Regulatory Issues - Huluwa Pharmaceutical has faced multiple regulatory penalties this year, including being ordered to rectify issues related to annual report disclosures [5][7]. - The company’s stock was placed under risk warning and renamed "ST Huluwa" starting April 30, 2025, due to financial reporting issues [7]. - The company received criticism for failing to disclose performance forecasts in a timely manner, leading to disciplinary actions against its executives [7][8].

上述两款药品按照与参比制剂质量和疗效一致的技术要求审评并获批，批准后视同通过仿制药质量和疗 效一致性评价。 二甲双胍恩格列净片(Ⅰ)适应症为配合饮食控制和运动，适用于正在接受恩格列净和盐酸二甲双胍治疗 的2型糖尿病成人患者，用于改善这些患者的血糖控制。吸入用复方异丙托溴铵溶液适应症为适用于需 要多种支气管扩张剂联合应用的患者，用于治疗气道阻塞性疾病有关的可逆性支气管痉挛。 人民财讯9月1日电，ST葫芦娃（605199）9月1日晚间公告，公司近日收到国家药监局核准签发的关于 二甲双胍恩格列净片(Ⅰ)、吸入用复方异丙托溴铵溶液的《药品注册证书》。 ...

证券代码：605199 证券简称：ST 葫芦娃 公告编号：2025-065 海南葫芦娃药业集团股份有限公司 关于获得药品注册证书的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 海南葫芦娃药业集团股份有限公司（以下简称"公司"）近日收到国家药品监督管 理局（以下简称"国家药监局"）核准签发的关于二甲双胍恩格列净片（Ⅰ）、吸入用 复方异丙托溴铵溶液的《药品注册证书》。现将有关情况公告如下： 一、二甲双胍恩格列净片（Ⅰ） 注册分类：化学药品 4 类 规格：每片含盐酸二甲双胍 500mg 与恩格列净 5mg （一）药品基本情况 药物名称：二甲双胍恩格列净片（Ⅰ） 剂型：片剂 上市许可持有人：海南葫芦娃药业集团股份有限公司 受理号：CYHS2302981 药品批准文号：国药准字 H20255188 根据国家药监局网站数据查询，截至本公告披露日，除本公司外，国内还有 9 家企 业获批二甲双胍恩格列净片（I）。 截至目前，公司对该产品已累计投入研发费用人民币 1160.07 万元（未经审计）。 二、吸入用复方异丙托溴铵溶液 （一）药 ...