Core Viewpoint - BeiGene (06160) announced the grant of 16,500 restricted stock units to 143 recipients under the 2016 option and incentive plan, equivalent to 214,000 shares, representing approximately 0.01% of the company's total issued shares as of the announcement date [1] Summary by Categories - **Company Actions** - The board's compensation committee granted a total of 16,500 restricted stock units to 143 recipients [1] - The restricted stock units correspond to 214,000 shares [1] - **Shareholder Impact** - The granted shares represent about 0.01% of the total issued shares of the company as of the announcement date [1]

本公告乃根據上市規則第17.06A、17.06B以及17.06C條作出。於2025年11月10 日，董事會薪酬委員會根據2016期權及激勵計劃的條款向一百四十三名承授人授 出涉及合共16,463股美國存託股份的受限制股份單位。 2016期權及激勵計劃項下的受限制股份單位 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生或因依賴 該等內容而引致的任何損失承擔任何責任。 BeOne Medicines Ltd. 百濟神州有限公司 （根據瑞士法律註冊成立的公司） （股份代號：06160） 授出受限制股份單位 於2025年11月10日，董事會薪酬委員會根據2016期權及激勵計劃的條款授予一百 四十三名承授人合共16,463股美國存託股份受限制股份單位。該等受限制股份單 位相當於214,019股股份，約佔本公告之日公司發行股份總數的0.01%。 授出受限制股份單位詳情 受限制股份單位詳情如下： 1 授出日期： 2025年11月10日 承授人數目： 一百四十三名 已授出受限制股份單位涉及的 相關股份數目： 214 ...

Core Insights - The overall performance of companies listed on the Sci-Tech Innovation Board (STAR Market) has shown a strong rebound in the first three quarters, with a significant year-on-year net profit growth of 75% in Q3 [2] - The focus on "hard technology" has led to increased R&D investments, particularly in key industries such as integrated circuits, artificial intelligence, and biomedicine, contributing to the foundation for high-level technological self-reliance [2] Performance Overview - In the first three quarters, STAR Market companies achieved a total revenue of 1.11 trillion yuan, a year-on-year increase of 7.9%, and a net profit of 49.268 billion yuan, up 8.9% [2] - Excluding four leading photovoltaic companies, overall revenue and net profit growth rates were 14.6% and 30.6%, respectively, indicating an amplified growth momentum [2] - Over 70% of companies reported revenue growth, and nearly 60% saw net profit increases, with 158 companies experiencing net profit growth exceeding 50% [2] Industry Highlights - The STAR Market's top enterprises and growth-oriented companies complement each other well, with the Sci-Tech 50 Index companies accounting for 46% of revenue and 50% of net profit [3] - The Sci-Tech 100 Index companies demonstrated high growth elasticity, with revenue and net profit increasing by 12% and 134%, respectively, becoming the "vanguard" of performance growth [3] R&D Investment - Total R&D investment by STAR Market companies reached 119.745 billion yuan, 2.4 times the net profit, with a median R&D intensity of 12.4%, leading A-share sectors [4] - The biomedicine sector saw revenue growth of 11% and net profit growth of 48%, driven by the rapid commercialization of innovative drugs [4] - Nine first-class new drugs were approved for market entry during the reporting period, with significant international business development transactions totaling over 13 billion USD [4] Growth of Emerging Companies - 35 unprofitable companies in the Sci-Tech Growth Layer reported a revenue increase of 39% and a significant reduction in net losses by 65% [5] - These companies are focusing on R&D with a median R&D intensity of 44.3%, indicating a promising development trend [5] Competitive Advantages in Key Industries - The integrated circuit industry, crucial for technological self-reliance, saw 121 related companies achieve a revenue growth of 25% and a net profit growth of 67% [6] - Major players like SMIC and Huahong Semiconductor maintained high capacity utilization rates, with record sales revenue [6] - The AI industry has emerged as a new growth pillar, with significant revenue increases across the supply chain, particularly in computing and data transmission sectors [7] Renewable Energy Sector - In the photovoltaic sector, 17 related companies significantly reduced their net losses by 28% [7] - The lithium battery industry experienced a revenue growth of 7% and a net profit of 1.02 billion yuan, marking a return to profitability [7]

Core Insights - Chinese innovative pharmaceutical companies are gaining global competitiveness, with BeiGene and Innovent Biologics as representative examples, each following distinct paths to success [1][3][5] Company Paths - BeiGene has pursued a strategy of immediate globalization, facing significant risks and challenges, while Innovent Biologics initially focused on the domestic market before expanding internationally [1][4] - Innovent Biologics has established partnerships with major international pharmaceutical companies, such as a recent $11.4 billion strategic collaboration with Takeda Pharmaceutical [1][2] Financial Performance - In the first three quarters of 2025, Innovent Biologics reported product revenues of 8.63 billion yuan, with 21 product lines in development and 16 commercialized drugs [3] - BeiGene's revenue for the same period reached approximately 27 billion yuan, with over 40 drugs in clinical and commercial stages [3] Market Strategy - Innovent Biologics aims to achieve 20 billion yuan in revenue within three years, focusing on oncology-related drugs and diversifying its product lines [6] - BeiGene aspires to become a multinational enterprise from China, aiming to shorten the time for innovative drugs to reach markets in Southeast Asia [5][6] Industry Challenges - Both companies face common challenges in market access, pricing, and intellectual property protection, necessitating a problem-oriented approach to navigate the evolving landscape [7]

Core Insights - Chinese innovative pharmaceutical companies are gaining global competitiveness, with different paths taken by companies like BeiGene and Innovent Biologics [1][4][5] - Innovent's approach is seen as more replicable compared to BeiGene's aggressive global strategy, which is viewed as a product of a specific window of opportunity [6][11] Company Strategies - Innovent Biologics has established a strong domestic foundation before expanding internationally, recently securing a $11.4 billion strategic partnership with Takeda Pharmaceuticals [3][4] - BeiGene, on the other hand, has pursued a global strategy from its inception, with significant investments in local talent and operations across various regions [5][9] Financial Performance - In the first three quarters of 2025, Innovent reported product revenues of approximately 8.63 billion yuan, while BeiGene's revenues were around 27 billion yuan [4][5] - Both companies have a significant number of products in various stages of development, with Innovent having 21 product lines and BeiGene over 40 [4][5] Market Challenges - Both companies face common challenges in market access, commercialization pricing, and intellectual property protection, which are evolving in the industry [11] - The traditional path for innovative drugs involves initial development in Western markets, followed by generic competition in developing countries, which can take over a decade [8][9] Future Outlook - Innovent aims to achieve 20 billion yuan in revenue within three years, focusing on a diversified product line, particularly in oncology [9] - The Chinese innovative drug sector is expected to play a more significant role globally in the next 5 to 10 years, with advantages in engineering talent and patient recruitment speed [10][11]

Market Overview - A-shares indices collectively strengthened, with the Shanghai Composite Index reaching a ten-year high, and trading volume exceeding 2 trillion yuan, an increase of 969 billion yuan from the previous period [1] - The technology sector, particularly the domestic AI industry chain, saw significant gains, with the AI-focused ETF (589520) rising nearly 2% and attracting 31.59 million yuan in five days [1] Sector Performance Technology Sector - Alibaba's secret "Qianwen" project aims to compete with ChatGPT, enhancing the global AI application landscape [1] Chemical Sector - The chemical ETF (516020) surged by 3.95%, reaching its highest closing price since March 2023, driven by rising prices of lithium hexafluorophosphate and favorable government policies [1][10] - The National Energy Administration's guidance on promoting the integration of new energy is expected to drive direct project investments of approximately 250 billion yuan [1] New Energy and Electric Vehicles - The smart electric vehicle ETF (516380) and green energy ETF (562010) also saw significant gains, rising by 3.83% and 3.41% respectively [1] Hong Kong Market - The Hong Kong innovation drug ETF (520880) experienced a substantial increase of 4.6%, indicating a potential second wave of the innovation drug market [2][4] - The newly launched Hong Kong information technology ETF (159131) focusing on the chip industry rose by 1.11%, with a trading volume exceeding 80 million yuan [2] Future Outlook - CITIC Securities anticipates 2026 to be a pivotal year for China's development, with a focus on new industries and consumption growth [4] - The chemical sector is expected to benefit from increased demand in the lithium battery supply chain, with significant price fluctuations noted [14] - The outlook for the non-ferrous metals sector remains strong, with a year-to-date increase of 75.9%, driven by robust earnings and strategic resource policies [18][20]

Group 1 - The innovative drug sector has shown strong performance, with notable stock increases for companies such as Sangamo Therapeutics (up 10.11%), Innovent Biologics (up 7.52%), BeiGene (up 7.34%), China Biologic Products (up 6.79%), and I-Mab (up 6.37%) [1] - In Q3, the innovative drug sector reported a revenue growth of 1.98% year-on-year and a net profit attributable to the parent company increased by 7.25% year-on-year [1] - Despite adjustments since September, the overall trend for the innovative drug industry remains positive, supported by domestic policy and the Federal Reserve entering a rate-cutting cycle, with a significant number of licensing deals expected in the next six months to a year [1] Group 2 - Guotai Junan Securities noted that the innovative drug sector continued to experience high revenue growth and profitability turnaround in Q3, indicating a long-term positive development trend for China's innovative drug industry [2] - The explosive growth in business development (BD) transactions has been a key highlight in recent years for the domestic innovative drug sector [2] - For most domestic innovative drugs, external licensing is often just the starting point for global development, with the progress of partners in overseas development and subsequent global clinical data readings enhancing the commercial certainty of products in the global market [2]

Group 1 - The innovative drug sector shows strong performance, with notable stock price increases for companies such as 三生制药 (up 10.11%), 先声药业 (up 7.52%), and 百济神州 (up 7.34%) [1] - In Q3, the innovative drug sector's revenue grew by 1.98% year-on-year, while net profit attributable to shareholders increased by 7.25% year-on-year [1] - Despite adjustments since September, the overall trend for the innovative drug industry remains positive, supported by domestic policies and the Federal Reserve entering a rate-cutting cycle [1] Group 2 - The innovative drug sector continued to experience high revenue growth and profitability turnaround in Q3, indicating a long-term positive development trend [2] - The surge in business development (BD) transactions highlights the growth potential of the Chinese innovative drug industry [2] - For most domestic innovative drugs, external licensing is often just the starting point for global development, with subsequent clinical data enhancing commercial certainty in global markets [2]

Core Viewpoint - BeiGene reported a 41% year-on-year revenue growth to $1.41 billion, with non-GAAP net profit reaching $125 million, exceeding market expectations [1] Group 1: Financial Performance - Revenue increased by 41% to $1.41 billion [1] - Non-GAAP net profit reached $125 million, surpassing market forecasts [1] Group 2: Future Projections - Based on the rapid growth of zanubrutinib sales and effective cost control, the profit forecast for 2025 has been raised by 56% to $331 million [1] - The profit forecast for 2026 remains unchanged [1] Group 3: Ratings and Target Prices - The company maintains an "outperform" rating [1] - Target prices for A-shares, H-shares, and US shares have been adjusted upwards by 3.2%, 3.3%, and 3.7% respectively, to 320 CNY, 250 HKD, and 420 USD [1]

Group 1 - The core viewpoint of the news highlights the continuous rise of innovative drugs in the Hong Kong stock market, driven by strong performance from companies like BeiGene and 3SBio, leading to a significant increase in the Hang Seng Innovative Drug ETF [1] - BeiGene reported Q3 revenue of 10.077 billion yuan, a year-on-year increase of 41.1%, and a net profit of 689 million yuan, marking a turnaround from losses [1] - The innovative drug sector is experiencing fundamental improvements due to policy support, performance realization, and accelerated international expansion, indicating significant mid-to-long-term investment value [1] Group 2 - A breakthrough in policy is noted with the introduction of a "commercial insurance innovative drug catalog" in the 2025 national medical insurance negotiations, which is expected to improve cash flow for pharmaceutical companies and optimize the payment ecosystem for innovative drugs [1] - The performance of leading pharmaceutical companies in Q3 2025 shows a transition from a "research and development investment phase" to a "commercialization harvest phase," with significant reductions in losses or profitability being achieved [1] - The international expansion of Chinese innovative drugs is accelerating, with total foreign licensing transactions exceeding 100 billion USD in the first ten months of 2025, reflecting the growing recognition of Chinese drug pipelines by multinational corporations [1] Group 3 - The Hang Seng Innovative Drug ETF (159316) has seen significant capital inflow, with a net inflow of 1.298 billion yuan over the past 20 days, bringing its total size to 4.178 billion yuan [3] - This ETF is the only product tracking the Hang Seng Hong Kong Stock Connect Innovative Drug Index, focusing on core enterprises in the innovative drug industry, excluding CXO companies [3] - Key weighted stocks in the ETF include leading companies such as BeiGene, Innovent Biologics, WuXi Biologics, and CanSino Biologics, providing investors with a convenient tool for exposure to cutting-edge innovative drug companies in Hong Kong [3]