证券代码：002422 证券简称：科伦药业 四川科伦药业股份有限公司投资者关系活动记录表 编号：0074 | | □分析师会议 □特定对象调研 | | --- | --- | | 投资者关系活 | □媒体采访 √业绩说明会 | | | □新闻发布会 □路演活动 | | 动类别 | □现场参观 | | | □其他：电话调研 | | 参与单位名称 | 本 次 业 绩 说 明 会 以 文 字 问 答 方 式 在 进 门 财 经 召 开 （ 网 址 ： | | 及人员姓名 | https://s.comein.cn/syfe7cqa）。 | | 时间 | 2025 年 5 月 6 日 15：00-17：00 | | 地点 | 线上 | | | 董事长刘革新先生；独立董事任世驰先生；副总经理兼财务总监赖德贵先 | | 上市公司接待 | 生；副总经理兼董事会秘书冯昊先生；销售负责人戈韬先生；科伦博泰首席 | | 人员姓名 | 财务官兼董事会秘书周泽剑先生；川宁生物副总经理兼董事会秘书顾祥先 | | | 生。 | | | 公司就投资者对经营现状、发展战略、研发进展等方面所提的问题进行了回复，主要内 | | | 容如下： | ...

心脉医疗 20250508 摘要 • 心脉医疗 2025 年 Q1 净利润同比下降 31.27%至 1.22 亿元，主要受市场 环境变化和产品策略调整影响，但国际市场收入同比增长超 93%，占比提 升至 16%以上，海外市场拓展迅速。 • 公司研发投入占营收比例略有下降，但持续推进创新，目前有 9 款在研产 品进入国家创新医疗器械特别审查程序，预计 2025 年将有 6 款产品获批， 加速国产替代。 • 主动脉介入领域，Creatus 分支型支架已上市，AKE 胸主动脉多分支支架 进入绿色通道，ARB 腹主动脉支架完成临床植入，产品线不断丰富。 • 外周动脉介入领域，可解脱纤维毛栓塞弹簧圈已提交注册，药物球囊扩张 导管完成临床入组，外周血管药物洗脱支架处于临床试验阶段，并独家代 理外周血管冲击波导管。 • 肿瘤介入领域，经静脉肝内穿刺套件获批上市，3D 球囊完成注册资料递交， TIPS 覆膜支架完成临床植入，持续拓展肿瘤介入市场。 • 受集采预期影响，河北地区代理商可能受到影响，但正常手术供货稳定， 库存维持在 4 个月左右，经销商团队基本稳定，并有新代理商加入，渠道 持续拓展。 • 公司加速外周血管产品海外 ...

"医美三剑客"之一昊海生科（688366）突现利空。 昊海生科5月7日晚间披露的公告显示，公司收到控股股东、实际控制人之一蒋伟通知，其于近日收到中国证监会出具的《立案告知书》， 因涉嫌内幕交易，根据《中华人民共和国证券法》《中华人民共和国行政处罚法》等法律法规，中国证监会决定对其立案。 此外，昊海生科提到，公司将持续关注上述事项的进展情况，并严格按照有关法律法规的规定和要求，及时履行信息披露义务。 投融资专家许小恒表示，上市公司实控人被立案，即使与公司无关也可能会对公司产生负面影响。受此消息影响，5月8日，昊海生科低开 4.31%，开盘价为50.88元/股。截至当日收盘，昊海生科报52.26元/股，跌幅为1.71%，总市值121.9亿元。 股权关系显示，截至3月31日，蒋伟为昊海生科第一大股东，持有公司股份6652.8万股，持股比例为28.53%。蒋伟与游捷为夫妻关系，共同 为昊海生科控股股东、实际控制人。游捷为公司第二大股东，持股比例为17.29%，持有股份数量为4032万股。二人直接持股比例合计为 45.82%。目前，蒋伟未在公司任职，游捷担任昊海生科非执行董事。 资料显示，昊海生科是一家从事医疗器械和药 ...

Core Insights - The company reported a revenue of 1.132 billion yuan in 2024, a decrease of 4.58% year-on-year, and a net profit attributable to shareholders of 58.68 million yuan, down 20.35% year-on-year [1][2] - The company's net profit excluding non-recurring items saw a significant increase of 73.85%, reaching 53.23 million yuan [1][2] - Basic earnings per share decreased to 0.19 yuan, down 20.83% from the previous year [2] Financial Performance - Revenue for 2024 was 1,132,476,522.09 yuan, compared to 1,186,786,001.40 yuan in 2023, reflecting a decline of 4.58% [2] - Net profit attributable to shareholders was 58,675,175.44 yuan, down from 73,663,110.90 yuan, a decrease of 20.35% [2] - The net profit after excluding non-recurring items was 53,233,408.45 yuan, a substantial increase from 30,619,980.53 yuan, marking a growth of 73.85% [2] - Operating cash flow was 30,687,788.46 yuan, down 14.02% from the previous year [2] - Total assets at the end of 2024 were 3.80 billion yuan, a 10.38% increase from 3.44 billion yuan in 2023 [2] Business Segments - The pharmaceutical segment generated 989 million yuan in revenue, a decline of 13.48%, accounting for 87.34% of total revenue, facing pressure from centralized procurement policies [3] - The veterinary medicine segment saw a dramatic increase in revenue to 75.20 million yuan, up 740.79%, driven by the launch of the Lingbao veterinary project and increased demand in the animal health market [3] - The functional food sector grew by 170%, and the cosmetics sector grew by 100%, emerging as new growth areas for the company [3] Research and Development - The company invested 1.22 billion yuan in R&D in 2024, representing 10.78% of total revenue, with a capitalization rate of 13.83% [3] - Ongoing projects include the development of new drugs such as Nimodipine tablets and Asenapine sublingual tablets, with three new patents granted, bringing the total to 137 patents focused on the nervous and cardiovascular systems [3]

证券代码： 002437 证券简称：誉衡药业 哈尔滨誉衡药业股份有限公司投资者关系活动记录表 | | | | | | 2025-002 | | --- | --- | --- | | | 特定对象调研 分析师会议 √ □ | | | 投资者关系活动 | □ 媒体采访 □ | 业绩说明会 | | 类别 | □ 新闻发布会 □ 路演活动 | | | | □ 现场参观 | | | | □ 其他 （请文字说明其他活动内容） | | | 参与单位名称及 | 惠升基金管理有限责任公司 张政 | | | 人员姓名 | | | | 时间 | 年 月 日 2025 5 8 15:30~16:40 | | | 形式 | √现场 口网上 口电话会议 | | | 上市公司接待人 | 董事、副总经理、董事会秘书：刘月寅 | | | 员姓名 | 证券事务高级经理：王孟云 | | | | 问题 1：与第一三共的合作情况及后续是否还有其他合作 | | | | 计划？ | | | | 回复： | | | | 公司与第一三共已有近十年的合作关系，公司专业化推广能 | | | | 力获得了第一三共的高度认可，双方合作关系不断巩固与加深，合 | | ...

Core Viewpoint - The company has emerged from the impact of centralized procurement, achieving strong growth in its traditional orthopedic segment on a low base, and successfully expanding into new business areas, maintaining a buy rating [1] Investment Highlights - The company maintains a buy rating, with projected EPS for 2025-2026 at 1.24/1.64 yuan, and a new EPS forecast for 2027 at 1.99 yuan. The target PE for 2025 is set at 36X, with an updated target price of 44.64 yuan (previously 42.65 yuan) [2] - In 2024, the company achieved revenue of 2.136 billion yuan (up 39.3% YoY) and a net profit attributable to shareholders of 357 million yuan (up 505%). The non-recurring net profit was 285 million yuan (up 2604%) [2] - In Q1 2025, the company reported revenue of 550 million yuan (up 28.8% YoY) and a net profit of 103 million yuan (up 67%), with non-recurring net profit at 97 million yuan (up 97%) [2] - The performance in 2023 was affected by inventory adjustments due to centralized procurement in 2021 and 2022, leading to a low base for 2024, which is expected to see continued growth as the impact clears [2] Orthopedic Product Lines - The core orthopedic product lines have recovered from the impact of centralized procurement, with trauma and spinal product lines showing continuous sales growth. In 2024, trauma product sales are expected to reach 821 million yuan (up 43.4%), with a gross margin increase of 3.67 percentage points to 75.34% [3] - Spinal product revenue in 2024 is projected at 388 million yuan (up 36.9%), with a slight decline in gross margin by 1.06 percentage points to 67.66% due to high prices before centralized procurement [3] - Joint products are also expected to maintain good growth, with projected revenue of 189 million yuan (up 21.1%) in 2024 [3] Non-Orthopedic Consumables - The non-orthopedic consumables business is showing good growth potential, aiming to contribute to a second growth curve for the company. In 2024, R&D investment is expected to reach 307 million yuan, accounting for 14.4% of revenue [4] - Minimally invasive surgical products are projected to achieve revenue of 363 million yuan (up 26.5%) with a gross margin increase of 1.77 percentage points to 78.19% [4] - Revenue from neurosurgical products is expected to be 103 million yuan (up 26.3%), dental products at 67 million yuan (up 28.2%), and other products at 162 million yuan (up 141%) [4]

Core Viewpoint - The company is facing significant challenges due to the investigation of its controlling shareholder for insider trading, alongside declining performance in key business segments and increasing competition in the industry [1][5][6]. Financial Performance - The company's overall revenue growth has slowed, with 2024 revenue at 2.698 billion (up 1.64% year-on-year) and net profit at 420 million (up 1.04% year-on-year) [2]. - In Q1 2025, revenue dropped to 619 million (down 4.25% year-on-year) and net profit to 90 million (down 7.41% year-on-year) [2]. - R&D expenses decreased significantly by 25.4%, while sales and management expense ratios increased by 0.54 and 1.52 percentage points, respectively [2]. Business Segmentation - The medical aesthetics segment showed weak growth, with 2024 revenue at 1.2 billion (44.38% of total), and hyaluronic acid product revenue at 742 million (up 23.23% year-on-year), but a sharp decline from 95.45% growth in 2023 [3]. - The ophthalmology segment reported revenue of 858 million (down 7.60% year-on-year), with intraocular lens revenue at 328 million (down 14.06% year-on-year), primarily impacted by a 60% price drop from the fourth national procurement [3]. - The orthopedics segment generated revenue of 457 million (down 4.11% year-on-year), with profits affected by price declines from provincial procurement for sodium hyaluronate injections [4]. Dividend and Market Concerns - The company's high dividend payouts have raised market concerns, with the controlling shareholder couple receiving approximately 344 million in cash dividends from 2019 to 2024, and the 2024 dividend accounting for 54.92% of net profit [4]. Industry Risks - The investigation into the controlling shareholder poses risks, including potential stock freezes or selling restrictions, which could undermine market confidence and highlight governance issues due to concentrated ownership [5][6]. - The company faces intense competition in the medical aesthetics sector, with rivals like Huaxi Biological and Aimeike, and pressure from new technologies impacting traditional markets [6]. - The normalization of centralized procurement is leading to a downward price trend for ophthalmology and orthopedics products, necessitating faster innovation to maintain profit margins [7]. Cash Flow and Asset Quality - Concerns regarding cash flow and asset quality are evident, with accounts receivable at 316 million (75.18% of net profit) and a low inventory turnover rate of 0.39 times [8]. - In Q1 2025, operating cash flow was 86 million, while cash outflow from investment activities was 179 million [8].

Core Viewpoint - The recent investigation of Jiang Wei, a major shareholder of Haohai Biological Technology, by the China Securities Regulatory Commission for suspected insider trading is not expected to significantly impact the company's operations or stock performance [1][2]. Company Overview - Haohai Biological Technology is recognized for its "medical aesthetics + ophthalmology" business model, with a focus on high-margin products such as artificial lenses and medical-grade hyaluronic acid [2][3]. - The company is the first biopharmaceutical firm listed on both the Hong Kong Stock Exchange and the Shanghai Stock Exchange's Sci-Tech Innovation Board [2]. Financial Performance - Revenue has shown consistent growth from 1.3 billion yuan in 2020 to 2.6 billion yuan in 2024, while net profit increased from 200 million yuan to 400 million yuan during the same period, despite a significant drop in 2022 [2][3]. - In 2024, the company reported revenue of 2.698 billion yuan, a year-on-year increase of 1.64%, and a net profit of 420 million yuan, up 1.04% [3]. Market Challenges - The medical aesthetics and ophthalmology sectors are facing increased competition and price reductions due to national procurement policies, leading to stagnation in revenue growth for 2024 [3]. - The medical aesthetics segment has shown signs of growth fatigue, with revenues from medical beauty and wound care products increasing from 460 million yuan in 2021 to 1.2 billion yuan in 2024, but growth rates are declining [3]. Product Development - In July 2024, Haohai Biological Technology received approval for its fourth-generation hyaluronic acid product, Hai Mei Yue Bai, aimed at treating moderate to severe nasolabial folds, positioning it as a potential growth driver in the high-end medical aesthetics market [4]. - The product is priced at 13,800 yuan for 1ml and 19,800 yuan for 2ml, indicating a premium positioning [4]. Recent Performance - In the first quarter of 2024, the company experienced a decline in both revenue and net profit, with revenue at 619 million yuan, down 4.25%, and net profit at approximately 90.31 million yuan, down 7.41% [4].

Core Viewpoint - The company, Haohai Biological Technology (688366.SH), is facing scrutiny as its controlling shareholder, Jiang Wei, has been notified of an investigation by the China Securities Regulatory Commission for suspected insider trading, which has raised concerns among investors [1][3]. Company Overview - Haohai Biological Technology is a well-known producer of hyaluronic acid in China, with its founders Jiang Wei and You Jie being the controlling shareholders [1]. - The company has been listed on both the Hong Kong Stock Exchange and the Shanghai Stock Exchange, making it the first biopharmaceutical company to achieve dual listing on the "H+ Sci-Tech Innovation Board" [1]. Financial Performance - In 2024, Haohai Biological Technology reported total revenue of 2.698 billion yuan, a year-on-year increase of 1.64%, while the net profit attributable to shareholders decreased by 1.12% to 379 million yuan [2]. - The overall gross margin slightly declined from 70.46% to 69.89% in 2024, attributed to a significant drop in sales prices of certain products due to new rounds of national or provincial procurement [2]. - The company's revenue from the ophthalmology sector saw a notable decline, with the cataract product line generating 420.73 million yuan, down 15.33% year-on-year [2]. Market Reaction - Following the announcement of Jiang Wei's investigation, Haohai Biological Technology's stock experienced a decline of 4.81% in early trading on May 8, closing down 0.70% at 52.80 yuan, with trading volume significantly increasing compared to the previous day [3].

将投中网设为"星标⭐"，第一时间收获最新推送 长高，仍是一门好生意。 作者丨 胡香赟 编辑丨 海若镜 来源丨 36氪Pro 我想"再高一点" 春日，宜万物生长，包括人类幼崽的身高。 在讲究科学的时代，孩子的身高理所应当地也应遵循某种可量化的生长公式。 一个颇受大众认可的方法是，根据父母身高来预测孩子未来的身高区间。比如，男孩子的身高区间= （父亲身高+母亲身高+13厘米）÷2±7.5厘米。 公式前半部分就是所谓的"遗传靶身高"，即由遗传决定的无法改变的身高基数。而后半部分的"±7.5 厘米"，则是可以通过后天努力改变的部分——只需要"充分发挥孩子的生长潜能"。 梁宇在一家药企从事研发工作，出于职业敏感，女儿萱萱还在上幼儿园时，就开始关注她的身高问 题。她坦言自己和先生都不算高，对孩子未来的身高"没有过大期待，她个子不高，这点从小就能看 出来"。 尽管如此，萱萱上大班后，梁宇还是开始给她报了跳绳兴趣班。运动、光照、补充维生素D，最初梁 宇选择的是最朴素的科学"长个儿"方法。 几年后，萱萱在跳绳比赛里拿了奖，但身高年增长一直保持在5厘米左右。按照一般值，许多小朋友 能达到7、8厘米。原本，梁宇已经接受了这个结果， ...