证券研究报告·公司点评报告·中药Ⅱ 方盛制药（603998） 2024年报&25年一季报点评：业绩符合预期， 多产品矩阵保障业绩平稳 买入（维持） | [Table_EPS] 盈利预测与估值 | 2023A | 2024A | 2025E | 2026E | 2027E | | --- | --- | --- | --- | --- | --- | | 营业总收入（百万元） | 1,629 | 1,777 | 2,015 | 2,277 | 2,562 | | 同比（%） | (9.12) | 9.15 | 13.36 | 12.99 | 12.54 | | 归母净利润（百万元） | 186.82 | 255.22 | 309.13 | 376.74 | 450.44 | | 同比（%） | (34.64) | 36.61 | 21.12 | 21.87 | 19.56 | | EPS-最新摊薄（元/股） | 0.43 | 0.58 | 0.70 | 0.86 | 1.03 | | P/E（现价&最新摊薄） | 22.82 | 16.71 | 13.79 | 11.32 | 9.47 | [Table_Tag ...

证券研究报告 公司研究 [Table_ReportType] 公司点评报告 [Table_StockAndRank] 奥精医疗(688613) | 投资评级 | 买入 | | --- | --- | | 上次评级 | 买入 | 曹佳琳 医药行业分析师 执业编号：S1500523080011 邮 箱：caojialin@cindasc.com 相关研究 [Table_OtherReport] 仿生矿化胶原技术领先，人工骨修复 材料市场龙头正扬帆 信达证券股份有限公司 CINDA SECURITIES CO.,LTD 北京市西城区宣武门西大街甲127号金隅大厦B 座 邮编：100031 [Table_Title] 业绩短期承压，市场拓展加速，成长动能充 沛 [Table_ReportDate] 2025 年 05 月 02 日 [Table_S 事件：公司发布 ummary]2024 年年报和 2025 年一季报，2024 年实现营业收入 2.06 亿元（yoy-9.03%），归母净利润-0.13 亿元（yoy-123.35%），扣非归母净 利润-0.28 亿元（yoy-210.11%），经营活动产生的现金流量净 ...

Core Viewpoint - The A-share pharmaceutical and biotechnology sector demonstrated resilience in 2024 despite a complex external environment, with innovative drugs entering a phase of realization and development progress catalyzing growth, unaffected by trade wars, positioning it as a key investment theme for 2025 [1][8]. Overall Performance - A-share pharmaceutical and biotechnology companies reported stable performance, with total revenue in 2024 reaching 2.47 trillion yuan, slightly down from 2.50 trillion yuan in 2023, and a net profit attributable to shareholders of 140.26 billion yuan [2][3]. Revenue Breakdown - The overall sector had 499 companies, with a total revenue of 24,651.04 billion yuan in 2024, reflecting a year-on-year decrease of 1.50%. The first quarter of 2025 saw total revenue of 6,037.04 billion yuan, down 6.14% year-on-year [3]. - Sub-sectors such as chemical pharmaceuticals, pharmaceutical commerce, and medical devices achieved positive revenue growth in 2024, while only the medical services sector showed positive growth in Q1 2025 [4]. Individual Company Performance - Among the companies, 234 reported revenue growth in 2024, with 59 companies exceeding a 20% increase. In terms of net profit, 231 companies saw growth, with 140 exceeding 20% [5]. - Shanghai Pharmaceuticals achieved revenue of 275.25 billion yuan in 2024, up 5.75%, with a net profit of 4.55 billion yuan, a 20.82% increase. The company also reported a significant increase in R&D investment [5]. - Jiuzhoutong reported revenue of 151.81 billion yuan in 2024, a 1.11% increase, driven by stable growth in its pharmaceutical distribution business and rapid growth in emerging sectors [6]. Market Attention - The pharmaceutical and biotechnology sector has garnered significant market attention since April, with many companies receiving institutional research interest, particularly those involved in innovative drugs [7]. - Huadong Medicine's recent annual report and Q1 performance attracted considerable institutional investor interest, focusing on product development and future industry trends [7]. Investment Outlook - Analysts remain optimistic about innovative drugs, overseas expansion, and the clearing of procurement policies, suggesting that the sector is entering a growth phase with potential in insulin, orthopedics, and certain generic drug companies [8]. - The market is expected to see increased activity in mergers and acquisitions as the pharmaceutical market undergoes a phase of concentration [8].

Core Viewpoint - The company reported a decline in Q1 2025 revenue and net profit, but anticipates a recovery in performance in subsequent quarters through strategic initiatives and brand development [1][2]. Financial Performance - Q1 2025 revenue reached 1.608 billion yuan, a year-over-year decrease of 16.53% - Net profit attributable to shareholders was 90 million yuan, down 31.06% year-over-year - Non-recurring net profit was 72 million yuan, reflecting a 36.16% year-over-year decline [1]. Strategic Initiatives - The company is accelerating integration with China Resources Sanjiu to reshape its sales model, facing short-term pressures due to retail pharmacy consolidation and other factors [2]. - There is an emphasis on enhancing channel efficiency, terminal coverage, and brand product penetration, leveraging major products to drive performance recovery [2]. Brand Development - The company focuses on the "Kunzhong Medicine 1381" brand strategy, concentrating on key products like Shenling Baizhu Powder and Shugan Granules, utilizing a comprehensive media approach for brand positioning [2]. - The "Four Strengths Construction" initiative is aimed at improving terminal coverage and sales performance [2]. Academic and Product Development - The company has received awards for its research projects in collaboration with China Resources, laying a foundation for developing major traditional Chinese medicine products [2]. - The company is committed to enhancing its product offerings and brand identity in the chronic disease management sector, responding to market pressures [2]. Profit Forecast - Revenue projections for 2025-2027 are 8.969 billion, 10.076 billion, and 11.326 billion yuan, with year-over-year growth rates of 6.75%, 12.34%, and 12.41% respectively - Net profit forecasts for the same period are 717 million, 865 million, and 1.043 billion yuan, with growth rates of 10.63%, 20.68%, and 20.54% respectively - The current price-to-earnings ratios are projected at 16, 13, and 11 times [3].

Core Viewpoint - 2024 is a significant downturn year for Zhending Pharmaceutical, marked by substantial financial losses and operational challenges, revealing both immediate and long-term vulnerabilities in the company's business model [2][3]. Financial Performance - The company reported a total revenue of 2.971 billion yuan in 2024, a year-on-year decline of 18.06% - The net profit attributable to shareholders was a loss of 1.329 billion yuan, representing a staggering year-on-year drop of 2920.55% - The non-recurring net profit was -686 million yuan, down 491.35% year-on-year [2][5]. Non-Operating Losses - Major non-operating losses stemmed from an arbitration dispute with former subsidiary Beijing Landi Pharmaceutical, which resulted in a 1.4 billion yuan penalty for producing substandard drugs - The arbitration claim amounted to 1.467 billion yuan, with a settlement of 500 million yuan directly impacting the company's financials, accounting for 46.36% of total profit for the period [3][4]. Core Business Weakness - The pharmaceutical production and sales revenue fell to 2.313 billion yuan, down 20.50% year-on-year, while the medicinal plant cultivation revenue decreased to 634 million yuan, a decline of 8.99% - The simultaneous contraction in core business areas indicates a persistent weakening of market competitiveness [5][6]. Product Competition - The company's key products, including Fufang Kucan Injection and Dafeixin Minoxidil Lotion, face increasing competition in the market - Dafeixin's market share rose to 47.3% in 2024, but it does not hold the patent for Minoxidil, exposing it to competitive risks from other players like Sanofi's Mandi, which commands a 72.6% market share in the Minoxidil sector [6][7]. Innovation and R&D Challenges - The company has faced significant setbacks in innovation, with 27 drugs entering national or provincial procurement, but 8 of these had zero actual procurement volumes - The termination of several key R&D projects indicates a lack of new product development, which is critical for future growth [8][9]. International Expansion and Cost Management - Despite claims of pursuing international registration for Fufang Kucan Injection and other initiatives, R&D expenses were only 351 million yuan, about 11.82% of revenue, with no substantial progress reported - The gross margin for medicinal plant cultivation was only 12.7%, significantly lower than industry leader Tongrentang, which exceeds 25% [10].

经本公司审慎研究，决定自2025年5月1日起按照各省份对于未中选产品的规则和要求，陆续调整、梯度 降低该药物的市场零售价格，相比此前中标价格降价幅度不低于 35%。 本次价格调整后，预计对该药物2025年第二季度及后续执行期间的销售收入产生不利影响。鉴于该药物 价格调整及本次集采未中选后销售量下滑等因素，预计将导致该药物2025年度销售收入同比下降，其对 本集团实际业绩影响最终以本集团经审计的2025年度财务数据为准。本公司将依据香港联合交易所有限 公司证券上市规则及其他相关规则及规定，及时就本集团的财务表现另行刊发公告。 未来，本公司将继续维持与国内外现有主要供应商的长期合作;确保生产制造体系团队稳定;强化生产全 过程质量控制。本公司秉持对患者负责的经营理念，将一如既往保障药品质量稳定可靠。 本公司将持续关注省级、直辖市等地方销售政策，继续梳理优化营销网络，研究各省医保政策、商保政 策及招标方案;积极开发空白医疗机构，加强在民营医院、盈利性医疗机构等终端市场的开拓力度，提 升终端服务能力;通过临床疗效数据、患者教育等学术推广等方式强化产品差异化优势，提升品牌影响 力。 本集团将持续加大研发投入，加速研发项目 ...

深圳市新产业生物医学工程股份有限公司 深圳市新产业生物医学工程股份有限公司 投资者关系活动记录表 证券代码：300832 证券简称：新产业 编号：2025-004 投资者关系活动记录表 | 投资者关系 | □媒体采访 ☑业绩说明会 | | --- | --- | | 活动类别 | □新闻发布会 □路演活动 | | | □现场参观 | | | ☑其他 线上交流 | | 参与单位名 | 共计 120 家机构，163 名参会人员，详见附件《与会机构名单》； | | 称及人员姓 | 以及通过深交所"互动易"平台"云访谈"栏目参加新产业 2024 | | 名 | 年度业绩说明会的全体投资者 | | 时间 | 年 月 日-4 月 日 2025 4 27 30 | | | 23 | | | 栏目 | | 待人员姓名 | 副总经理兼财务总监 丁晨柳 | | | 独立董事 伍前辉 | | | 投资者关系负责人 吕宇宁 | | | 公司于 月 日发布了《2024 年年度报告》《2025 4 26 | | | 了线上和线下交流，本次交流涉及的经营要点及主要互动提问 | | 投资者关系 | | | 活动主要内 | 一、公司 年度及 ...

Q1 受制行业承压，坚持研发驱动，新品稳步推进。公司 Q1 眼科业务依 然受制集采导致的产品销售价格下滑，同时医美终端消费延续疲软态势， 公司作为医美玻尿酸核心厂商，受到市场一定影响，收入略微下降。公 司长期坚持自主创新和研发驱动，1）眼科板块：2025 年 1 月及 2 月分 别获批疏水模注散光矫正非球面人工晶状体，以及预装式疏水模注散光 矫正非球面人工晶状体，伴随中高端晶状体陆续获批，市场份额有望不 断提高。2）医美板块：2024 年 7 月获批第四代玻尿酸"海魅月白"，产 品采用全球首创的有机交联技术，精准解决长期困扰消费者的玻尿酸残 留问题，有望协同"海魅"及"海魅韵"强化公司在高端玻尿酸市场的 领先地位。此外公司正推动加强型水光、涂抹型 A 型肉毒素、无痛交联 玻尿酸、外用治疗雄性脱发药物、羟基磷灰石医美填充剂、蛋白类皮肤 填充剂等产品的研发工作，医美板块具备强劲增长势能。 持续提质增效，费用率较为平稳。25Q1 公司费用率 51.79%/+0.25pct，其 中：销售费用率 31.35%/+0.49pct；管理费用率 14.26%/+1.50pct；研发费 用率 7.83%/-2.22pct；财务 ...

Core Viewpoint - Tonghua Dongbao reported a significant decline in revenue and net profit for 2024, primarily due to adverse factors such as the impact of centralized procurement and the termination of R&D projects, but showed signs of recovery in early 2025 with a revenue increase [1][2]. Financial Performance - In 2024, the company achieved revenue of 2.01 billion yuan, a year-on-year decrease of 34.66% [1] - The net profit attributable to shareholders was a loss of 43 million yuan, with a non-recurring net profit loss of 9 million yuan [1] - For the first half of 2024, revenue was 740 million yuan, while the second half saw a revenue of 1.27 billion yuan, representing a quarter-on-quarter increase of 71.55% [1] - The first quarter of 2025 showed a revenue increase of 10.17% year-on-year [1] Market Expansion - The new round of centralized procurement accelerated the market entry and volume growth of Tonghua Dongbao's insulin products, with significant new hospital admissions: approximately 1,400 for glargine insulin, 3,000 for aspart insulin, and 5,000 for premixed aspart insulin [1][2] - The total signed volume for insulin products in the latest procurement round reached approximately 45 million units, marking a substantial increase compared to the previous round [2] R&D and Innovation - The company is advancing its core pipeline, with promising clinical data for its GLP-1/GIP dual-target receptor agonist (THDBH120) and successful completion of key clinical trials for other innovative products [3] - The R&D expenses accounted for 22.42% of revenue in 2024, indicating a continued commitment to high R&D investment [4] - The company is expanding its treatment areas beyond diabetes to include gout and hyperuricemia, while exploring products with multiple indications such as glucose reduction and weight loss [4] Future Outlook - The company is expected to experience a commercial explosion of several key products between 2025 and 2027, creating a positive growth pattern of stable growth from existing products and rapid breakthroughs from new products [3]

Core Insights - The company reported a revenue of 2.704 billion yuan and a net profit attributable to shareholders of 438 million yuan for the year 2024, with a 20.23% year-on-year growth in pharmaceutical industrial revenue driven by optimized marketing strategies [1] Group 1: Financial Performance - In 2024, the company achieved a revenue of 2.704 billion yuan and a net profit of 438 million yuan [1] - The pharmaceutical industrial revenue grew by 20.23% year-on-year due to enhanced marketing model adjustments [1] Group 2: Market Participation and Product Offerings - The company actively participated in national drug procurement projects, securing 14 core specifications in the third batch of national traditional Chinese medicine procurement [1] - A total of 86 products from the company were included in the latest national medical insurance directory, with 35 classified as Category A and 51 as Category B [1] Group 3: Marketing Strategy and Network Development - The company has established a nationwide marketing network covering over 6,000 medical institutions across more than 30 provinces, integrating a full-chain service system from urban public hospitals to retail terminals [3] - The marketing strategy focuses on cardiovascular and respiratory diseases while expanding into pediatric and digestive health markets, utilizing diverse sales channels and marketing strategies to drive growth [2][3] - The company emphasizes a comprehensive marketing approach with a focus on sales capability enhancement across different business units, targeting commercial sales, medical terminal markets, and retail pharmacies [3]