Core Viewpoint - Marubi Biological has officially started construction on a Class III medical device pilot base in Zhuhai, focusing on the research and industrialization of recombinant collagen protein in the medical beauty field, indicating a strategic shift from a cosmetics company to a biotechnology company [1][3]. Company Developments - The project aims to deepen research into recombinant collagen protein, expanding its application from cosmetic beauty to medical beauty, reflecting Marubi's ambition to enhance its competitive edge in the cosmetics industry and explore new revenue streams in the medical sector [1][3]. - Marubi has changed its name from "Marubi Co., Ltd." to "Marubi Biological" and has invested in medical biomaterials companies, signaling a commitment to this new direction [1][3]. Market Trends - The focus on recombinant collagen protein aligns with Marubi's historical emphasis on anti-aging products, particularly in eye care, and the growing popularity of this ingredient in the skincare market [3][4]. - The market for recombinant collagen protein is still in its early stages, presenting opportunities for early entrants like Marubi to capture market share [3][4]. Research and Development Strategy - Marubi plans to invest over 1 billion yuan in recombinant collagen protein research by 2032, with specific milestones including obtaining medical device registration by 2026 and advancing into serious medical applications by 2028 [4][5]. - Despite the ambitious R&D plans, Marubi's R&D expenses have not kept pace with revenue growth, leading to a decline in R&D expense ratios from 2.80% in 2023 to 2.48% in 2024 [5][9]. Financial Performance - Marubi's revenue has shown significant growth, surpassing 2.2 billion yuan in 2023, a 28.52% increase from the previous year, with projections indicating potential revenue exceeding 3 billion yuan by 2025 [7][9]. - The company has successfully adapted its marketing strategies, particularly through online channels and product focus, contributing to its revenue growth [7][8]. Competitive Landscape - Marubi faces challenges from increasing online marketing costs and rising sales expenses, which have impacted profitability, with net profit margins decreasing from 26.56% in 2020 to 11.52% in 2024 [9][10]. - The reliance on a single ingredient, recombinant collagen protein, poses risks, as market trends can shift rapidly, potentially affecting long-term sustainability [9][10].

胶原蛋白赛道或将迎来竞争高峰期。 药企德展健康日前宣布，其重组Ⅲ型及XVII型人源化胶原蛋白已实现中试生产，并具备化妆品原料销 售能力。但在这项技术突破背后，横亘着医药级原料转化的巨大鸿沟——规模化生产线仍在建设中，真 正的产业化部署尚未完成。 事实上，在所有玩家头顶高悬的双重高压线并未松动：技术层面，医美级产品的规模化生产与质量控制 仍如绝壁矗立；准入层面，长达36个月的三类医疗器械审批周期与超千万元的单产品合规成本构筑着钢 铁闸门。 围绕重组胶原蛋白项目技术突破及申报节奏，21世纪经济报道以投资者身份致电德展健康。该公司工作 人员回复道："其技术路线与巨子生物等行业头部企业同属人源化胶原蛋白范畴，并无本质差别。当前 中试生产规模维持在500L水平，产品技术性能可满足护肤品、医美等商业化应用需求。" 但工作人员同时指出，由于尚未建立规模化量产能力，具体产业化路径仍需结合后续产能建设情况确 定。 德展健康产品结构显示，公司已布局重组胶原蛋白原料及其衍生产品体系。2024年，重组Ⅲ型人源化胶 原蛋白不仅实现原料销售，其创新的冻干海绵剂型产品也通过备案审批。 作为第三代胶原蛋白技术，该产品通过DNA重组技术构建三 ...

Investment Rating - The report initiates coverage with an OUTPERFORM rating, setting a target price of Rmb 419.80, indicating a potential upside of 25.5% from the current price of Rmb 338.65 [2][9]. Core Insights - Shanxi Jinbo Bio-Pharmaceutical is a leading domestic company in the industrialization of recombinant human collagen, holding three Class III medical device certificates for its products, which positions it favorably in the market [3][11]. - The company reported a revenue of Rmb 1.44 billion in 2024, reflecting a year-on-year growth of 84.92%, driven by significant increases in its medical devices, functional skincare products, and raw materials segments [3][8]. - The report anticipates revenue growth for 2025-2027 to reach Rmb 2.17 billion, Rmb 2.92 billion, and Rmb 3.72 billion, respectively, with growth rates of 55%, 37%, and 29% [9]. Summary by Sections Company Overview - Shanxi Jinbo Bio-Pharmaceutical specializes in recombinant collagen medical devices, with a focus on injectable products that are classified as Class III medical devices, which have stringent approval processes and high technical barriers [3][11]. - The company has established a significant market presence with its proprietary brand Wei Yimei and has also engaged in contract manufacturing for L'Oréal's SkinCeuticals brand [3][27]. Financial Performance - The company has shown consistent revenue and profit growth over the past five years, with a net profit of Rmb 732 million in 2024, up 144% year-on-year [8][9]. - The gross profit margin for 2024 was reported at 92.02%, with the medical device segment achieving a margin of 95.03% [8][9]. Product and Market Position - The medical device segment accounted for 87% of total revenue in 2024, with a compound annual growth rate (CAGR) of 94% from 2020 to 2024 [25][27]. - Jinbo Bio's main products include recombinant collagen injectables, which are primarily used in aesthetic medicine and surgical repair treatments [23][27]. Strategic Partnerships - The company has formed a strategic partnership with Yangshengtang, leveraging its extensive retail network of over 3 million outlets to enhance market penetration and brand visibility [4][20]. - This collaboration is expected to facilitate the application of Jinbo's collagen products across various sectors, including skincare and health products [4][20]. Research and Development - Jinbo Bio is actively investing in R&D, with a focus on its new drug EK1, which is in the pre-clinical stage and aims to address broad-spectrum antiviral needs [5][9]. - The company holds multiple patents for its core ingredients, enhancing its competitive edge in the high-end skincare market [4][20].

Investment Rating - The report suggests a positive outlook for the textile manufacturing sector, indicating a potential increase in market sentiment due to recent tariff adjustments by the US [1][12][13]. Core Insights - The textile manufacturing sector has seen a significant recovery in market sentiment, with key companies experiencing notable stock price increases from June 20 to July 26, with cumulative gains of 24.84% for Crystal International, 12.93% for Huayi Group, and 11.24% for Shenzhou International [1][9][10]. - Recent adjustments in US tariffs have reduced uncertainty, with the new rates set between 15% to 50%, which is significantly lower than previously proposed rates [12][13]. - The introduction of HiveCOL collagen by Jinbo Biotech represents a breakthrough in the anti-aging market, utilizing 100% humanized technology to address issues related to animal collagen [14][15]. Industry Data Tracking - In June, clothing retail saw a year-on-year growth of 1.9%, but a month-on-month decline due to factors such as the early 618 shopping festival and adverse weather conditions affecting foot traffic [16][29]. - The prices of raw materials remained stable, with fluctuations in cotton prices and a noted decrease in the price difference between domestic and imported cotton [18][21]. - The cosmetics retail sector experienced a decline of 2.3% year-on-year, while gold and jewelry retail grew by 6.1% year-on-year, indicating differing consumer trends [29]. Investment Recommendations - For clothing brands, Hai Lan Home is recommended for its strong profitability and potential for expansion in the outlet market, while Li Ning is seen as having a potential turning point in its operations [37][39]. - In the beauty sector, Jinbo Biotech is highlighted for its strong data resilience and upcoming product launches, while the gold and jewelry sector remains attractive due to rising gold prices, with recommendations for brands like Laopu Gold [39][40]. Market Review and News - The textile manufacturing sector saw a 2.34% increase in the last week, with notable performances from companies like Tianhong International and Langsha [40][44]. - Recent industry news includes the announcement of the "2024 Industry Top 100" by the China National Garment Association, with a slight decline in overall performance compared to 2023 [49][50].

Core Insights - Waldencast, the parent company of Obagi Medical, has announced the acquisition of Novaestiq, a company specializing in beauty and medical skin innovations, which includes exclusive rights to sell Saypha® hyaluronic acid injection gel products in the U.S. market [1][2] - This acquisition marks Obagi's entry into the "medical device" sector, which is gaining traction as over 22 beauty brands have launched more than 40 "medical device" products [1][13] Company Overview - Waldencast was founded by former L'Oréal executives and aims to build a leading global beauty and health platform through the development and acquisition of high-growth brands, including Obagi and Milk Makeup [2] - The acquisition of Novaestiq is a strategic move to expand Obagi's product line in the U.S. dermal filler market [2] Market Potential - The U.S. dermal filler market is projected to reach $2.2 billion by 2029, indicating significant growth potential for Waldencast's investment [3] - Saypha® has sold over 110 million units in more than 80 countries but is still awaiting FDA approval for the U.S. market [3] Financial Performance - Waldencast reported a net revenue of $274 million for 2024, a 25.5% year-over-year increase, with Obagi contributing $149 million, reflecting a 26.9% growth [7] - In Q1 2025, Waldencast's net revenue was $65.4 million, a 4.1% decline, while Obagi's revenue grew by 7.1% to $36.2 million [8] Competitive Landscape - The U.S. is the largest market for injectable medical aesthetics, accounting for approximately 20.8% of global treatment procedures [9] - The market for hyaluronic acid injectables is growing steadily, making it a competitive space with established brands like Restylane already present [9] Strategic Direction - Waldencast aims to leverage Obagi's existing market influence to capture new growth opportunities in the medical aesthetics sector [3][7] - The company is focusing on scientific innovation and clinical data-backed products to enhance its market position [7] Industry Trends - The global medical aesthetics market is expected to reach $35.3 billion by 2030, with a compound annual growth rate of 12.8% from 2024 to 2030 [13] - The trend of "cosmetic-medical integration" is becoming more prevalent, with beauty brands increasingly developing and marketing medical device products [13]

Core Viewpoint - The article highlights the rapid growth of the medical beauty market, particularly focusing on the product "Wei Yi Mei" from Jinbo Biotechnology, while also exposing the rampant issues of counterfeit products and unregulated practices within the industry [3][4][12]. Group 1: Product Overview - "Wei Yi Mei" is a flagship product of Jinbo Biotechnology, leveraging recombinant collagen technology, and has seen significant sales growth from 25,000 bottles in 2021 to 576,000 bottles in 2023, maintaining over 300% growth [3]. - The global sales of the first injectable recombinant humanized collagen freeze-dried fibers have surpassed 2 million units [3]. Group 2: Market Dynamics - The retail market size for recombinant collagen medical beauty injections in China reached 4.3 billion yuan in 2023, accounting for 6.4% of the total medical beauty injection market, with projections to grow to 14.3 billion yuan by 2027 [4]. - The retail market for recombinant collagen medical dressings also reached 11 billion yuan in 2023 [4]. Group 3: Industry Issues - The article reveals that the market is plagued by counterfeit products, with only 35% of medical beauty injectables in circulation being genuine, leading to over 30% of consumer complaints related to product quality [12]. - Numerous unauthorized medical institutions are offering services related to "Wei Yi Mei," often at prices significantly lower than the official retail price, which raises concerns about product authenticity [8][10]. Group 4: Regulatory Concerns - The article emphasizes the need for consumers to recognize "regular doctors, regular institutions, and regular products" as a defense against medical beauty risks [10]. - The rise of "medical beauty fast-track training classes" has contributed to the proliferation of unqualified practitioners, further endangering consumer safety [16][17].

Summary of Conference Call Notes Industry Overview - The discussion revolves around the cosmetics industry, specifically focusing on the trend and competitive landscape of collagen protein in cosmetics [1][7][8]. Key Points and Arguments 1. **Sales Performance During 618 Promotion** - The 618 promotion started earlier this year on May 13, compared to May 24 last year, leading to a need for year-over-year comparisons [1]. - Sales data from the first phase of the promotion (up to May 25) indicates a significant impact on brand performance [1]. 2. **Impact of Public Relations Incident on Kofumei** - Kofumei, a leading brand in the fat-free protein segment, experienced a 50% drop in sales on the Sunday following a public relations incident, despite a quick denial from the company [2]. - The initial sales growth target for Kofumei during 618 was 60-80%, but it is now estimated to be only 30% due to this incident [2]. 3. **Marketing and Sales Strategy** - Kofumei's marketing strategy involved leveraging major influencers, with one influencer accounting for 70% of pre-sale sales [3]. - The brand's advertising budget increased by 30% compared to last year, aiming for a top 3 ranking in sales [3]. 4. **Conversion Rate Decline** - Kofumei's conversion rate has dropped below 3, with some estimates as low as 2.5, affecting the effectiveness of their advertising spend [4]. - Negative reviews from influencers are impacting consumer perception and sales [4]. 5. **Overall Market Impact** - The overall sales contribution from the 618 promotion is expected to be around 15-20% of annual sales, indicating that while the short-term impact is significant, the long-term effects may be minimal [5]. 6. **Performance of Other Brands** - Other brands like Keli Jin and Perfect are experiencing strong growth, with Keli Jin expected to achieve over 100% growth and Perfect targeting over 80% growth [6][7]. - Perfect's small gold needle product is also performing well, with a growth rate of 50-60% [6]. 7. **Trends in Collagen Protein Segment** - There is a growing interest among brands to enter the collagen protein market, driven by perceived growth potential [7][8]. - The competitive landscape includes brands like Kofumei, Keli Jin, and Perfect, all of which are focusing on collagen products [8]. 8. **Challenges for New Brands** - New brands may find it difficult to enter the collagen protein market due to high technical barriers and established competitors like Kofumei [9][10]. 9. **Market Growth Projections** - The overall market for collagen products is expected to grow at a rate of over 50%, with increasing participation from major cosmetic brands [10][12]. 10. **E-commerce Strategy Changes** - The strategy for e-commerce platforms like Douyin has shifted, focusing less on low-price strategies and more on brand exposure during the promotion [13][14]. - Sales growth across platforms during the 618 promotion is optimistic, with Douyin reporting a 40-50% increase [15]. Additional Important Insights - The discussion highlights the importance of brand reputation and consumer perception in the cosmetics industry, particularly in the context of social media and influencer marketing [4][10]. - The potential for regulatory changes in response to the recent public relations incident may shape future industry standards [10].

Core Viewpoint - The company has demonstrated strong sales resilience despite recent challenges, with a significant recovery expected in online sales due to improved brand recognition and marketing efforts [1][2][3] Group 1: Sales Performance - In May and June, the combined GMV of the company's brands, 可复美 and 可丽金, reached 1.08 billion yuan, a year-on-year increase of 2%, with 可复美 declining by 2% and 可丽金 growing by 33% [1] - The strong sales performance in the first four months of 2025 led to a 38% year-on-year growth in GMV for the first half of 2025 [1] - The company is actively restoring live streaming frequency and increasing promotional efforts, which is expected to gradually revive sales [2] Group 2: Product Strength and R&D - The company is recognized as the first in China to scale the production of recombinant collagen skincare products, showcasing deep technical expertise in the collagen field [3] - R&D expenses have significantly increased from 11 million yuan in 2019 to 106 million yuan in 2024, with an R&D expense ratio of approximately 2% in 2024 [3] - Capital expenditures have risen from 75 million yuan in 2021 to 250 million yuan in 2024, indicating a commitment to expansion and innovation [3] Group 3: Future Outlook - The company expects online revenue for 可复美 and 可丽金 to grow by 10% and 35% respectively in the second half of 2025, with overall online revenue growth for 可复美 projected at 20% and 可丽金 at 60% for the year [3] - Offline sales, which account for 28% of the company's revenue, are anticipated to remain stable [2]

Group 1 - The core viewpoint of the report is that the target price for Giant Bio (02367) has been reduced from HKD 79.96 to HKD 73.54, corresponding to a projected P/E ratio of 29 times for 2025, while maintaining a "Buy" rating [1] - Giant Bio's brands, Kefu Mei and Keli Jin, achieved a combined GMV of approximately RMB 1.08 billion on Tmall, Taobao, and Douyin from May to June, reflecting a year-on-year growth of 2%. The strong sales in the first four months led to a rapid year-on-year growth of 38% in GMV for the first half of 2025 [1] - Despite a temporary slowdown in online sales growth due to public sentiment, the sales performance in May and June demonstrates the company's strong sales resilience in extreme conditions [1] Group 2 - The company is expected to gradually recover its sales as it increases promotional efforts and restores broadcast frequency, supported by a rich product portfolio and a dual-brand strategy that enhances its risk resilience [1] - The company is the first in China to scale the production of recombinant collagen skincare products, possessing deep technical expertise in the collagen field, which is considered a cornerstone for sales recovery [1] - Conservative estimates suggest that in the second half of 2025, online revenues for Kefu Mei and Keli Jin will grow by 10% and 35% year-on-year, respectively, with overall revenue growth for 2025 projected to slow to 23% [2]

Core Insights - Zhong Shanshan's investment of 3.4 billion yuan in Jinbo Biological, acquiring 10.58% equity, marks the largest cash capital increase in the history of the Beijing Stock Exchange, highlighting a significant shift in the medical beauty industry landscape [1][5] - Jinbo Biological, a leader in the recombinant collagen sector, holds three Class III medical device certifications, establishing a formidable technical barrier in the market [2] - The recombinant collagen market is projected to grow at a compound annual growth rate (CAGR) of 45%, reaching 219.38 billion yuan by 2030, making it a critical growth area for Zhong's health empire [3] Company Overview - Jinbo Biological's revenue for 2024 is expected to reach 1.443 billion yuan, a year-on-year increase of 84.92%, with a net profit of 732 million yuan, up 144.27% [2] - The company's gross margin for medical devices is an impressive 95.03%, surpassing that of major brands like Moutai [2] - Despite its strong financials, Jinbo Biological relies heavily on its flagship product, "Wei Yimei" injection, which accounts for over 88% of its medical device revenue, indicating a potential growth bottleneck due to limited consumer brand performance [2] Strategic Implications - Zhong Shanshan's investment is not merely financial but a strategic move to find new growth avenues as his other businesses face slowdowns [3] - The collaboration between Zhong's Yangshengtang and Jinbo Biological aims to leverage Yangshengtang's extensive retail network and marketing capabilities to enhance Jinbo's consumer outreach [3] - The 2 billion yuan capital increase will fund the development of a recombinant collagen FAST database and product development platform, utilizing AI and high-throughput technologies to accelerate innovation [3] Industry Dynamics - The recombinant collagen market is poised for intense competition, with major players like Juzhi Biological and Huaxi Biological entering the space, potentially disrupting Jinbo's market position [4] - Advances in synthetic biology are expected to significantly reduce production costs, transforming recombinant collagen from a luxury product to a standard skincare item, which may trigger price wars [4] - The success of consumer brands in the market, such as Juzhi Biological's "Ke Fumei" mask generating 5.5 billion yuan in annual revenue, underscores the importance of consumer engagement for growth [4] Conclusion - Zhong Shanshan's substantial investment in Jinbo Biological is a catalyst for accelerating growth in the recombinant collagen sector, setting the stage for a competitive landscape in the medical beauty industry [5] - The ability of Jinbo Biological to transition from a B2B focus to a more consumer-oriented approach will be critical in navigating the evolving market dynamics [5]