Core Insights - Fosun Pharma reported a revenue of 41.067 billion yuan in 2024, a slight decrease of 0.80% year-on-year, while net profit attributable to shareholders increased by 16.08% to 2.770 billion yuan [1][2] - The company achieved a net cash flow from operating activities of 4.477 billion yuan, reflecting a significant increase of 31.13% compared to the previous year, indicating improved free cash flow to support strategic transformation and R&D investments [2][3] Financial Performance - Revenue: 41.067 billion yuan in 2024, down from 41.400 billion yuan in 2023, a decrease of 0.80% [2] - Net Profit: 2.770 billion yuan in 2024, up from 2.386 billion yuan in 2023, an increase of 16.08% [1][2] - Net Profit (excluding non-recurring items): 2.314 billion yuan, a rise of 15.10% from 2.011 billion yuan in 2023 [2] - Basic Earnings per Share: 1.04 yuan [1] Business Segmentation - Pharmaceutical Revenue: 28.924 billion yuan, a decline of 4.29% year-on-year; key products like Hanquyou® (trastuzumab) saw global sales of 2.810 billion yuan, an increase of 11% [3] - Medical Devices and Diagnostics Revenue: 4.323 billion yuan, down 1.53% due to decreased demand for COVID-19 products [3] - Healthcare Services Revenue: 7.647 billion yuan, an increase of 14.61% driven by specialized construction and smart healthcare initiatives [3] R&D and Innovation - R&D Investment: 5.554 billion yuan, accounting for 13.52% of revenue; seven innovative drugs/biosimilars were approved for market [3] - Notable Approvals: Slulizumab received EU approval, and HLX14 (biosimilar to dezuizumab) is under review in the US and EU [3] - Collaboration: The company is exploring new directions in nuclear medicine and gene therapy through partnerships with industry funds [3] Shareholder Returns - Proposed Dividend: The company plans to distribute a cash dividend of 3.20 yuan per 10 shares (tax included) [3]

Core Viewpoint - 博济医药's 2024 annual report indicates significant revenue growth, but also highlights notable quarterly fluctuations in performance metrics [1] Financial Performance - The company achieved total revenue of 742 million yuan, representing a year-on-year increase of 33.50% [1] - Net profit attributable to shareholders was 28.78 million yuan, up 18.23% year-on-year [1] - The net profit after deducting non-recurring gains and losses was 19.30 million yuan, showing a substantial increase of 92.71% year-on-year [1] - However, there were quarterly declines, with total revenue rolling quarter-on-quarter down by 1.48%, net profit down by 35.47%, and net profit excluding non-recurring items down by 38.24% [1] Revenue Breakdown - Clinical research services revenue reached 597 million yuan, a significant increase of 44.12% year-on-year, with new contract value growing by 38.56% to 1.305 billion yuan [5] - Preclinical research services revenue was 84.32 million yuan, reflecting a growth of 7.70% year-on-year, with new contract value around 158 million yuan [6] - Other consulting services revenue decreased by 13.02% year-on-year to 42.22 million yuan, with new contract value approximately 5.2 million yuan [7] Business Segments - The company continues to lead in traditional areas such as liver disease, oncology, and endocrinology while making breakthroughs in emerging fields like immunology and gene therapy [5] - In the medical device sector, the company conducted nearly 80 clinical research services and 40 registration services, securing 13 Class III medical device registrations [5] - The company has established partnerships with over 900 clinical trial service organizations and signed strategic cooperation agreements with more than 40 institutions [5] R&D and Innovation - The company has received over 10 invention patents and is progressing well with multiple self-research projects [8] - The drug evaluation center successfully passed the GLP qualification re-examination and received the GLP certification [6] - AI technology is being utilized in the design of new target compounds to enhance research efficiency and accuracy [6]

• 临床试验进展缓慢： 尽管AI技术在分子设计、靶点发现起到提升效率和优化设计作用，但药物研发仍 需经过湿实验及较长的临床周期验证，产品进展存在不确定性。 本期Banglink从创业邦独家企业数据库睿兽分析精选11家AI药物研发领域优秀企业，覆盖多组学数据整 合、蛋白质结构预测、分子模拟优化、自动化实验平台、成药性智能评估等多个技术领域。如对精选项 目感兴趣，欢迎扫码进行委托联系！ AI药物研发是以数据驱动、算法赋能为核心，通过机器学习、生成式AI等技术重塑药物发现、优化及 临床试验全流程的创新领域。随着全球医药产业对效率提升的迫切需求，AI正从辅助工具升级为核心 驱动力 —— 据BCG报告，AI设计的药物分子在Ⅰ期临床试验成功率达80%-90%，远超传统方法的 40%-65%；部分企业已将药物发现周期从5-6年压缩至2-3年，研发成本降低30%-50%。 政策与资本双重加持下，行业进入爆发期：各国纷纷将AI制药纳入战略规划，国内《卫生健康行业人工 智能应用场景参考指引》明确84种应用场景，资本加速布局，2024年全球AI制药融资超50亿美元，晶泰 科技、英矽智能等企业管线快速推进，多款AI设计药物进入Ⅱ/Ⅲ ...

Group 1 - Central Huijin has invested 1.76 billion yuan in the pharmaceutical sector, indicating a potential emergence of a new high-performing stock similar to Double-Creation Pharmaceutical [1] - The National Medical Products Administration has released a draft aimed at optimizing the regulatory framework for high-end medical devices, with a target for the pharmaceutical industry to exceed 2 trillion yuan by 2029, growing at a compound annual growth rate (CAGR) of over 12% [1] - The number of Chinese pharmaceutical companies certified by cGMP has surged by 87% year-on-year, highlighting a significant acceleration in internationalization [1] Group 2 - Two key pharmaceutical stocks identified as targets of Central Huijin's investment are Xinlitai, which has the world's first dual-indication antihypertensive drug, and a company recognized as a hidden champion in antibiotics with a strong product pipeline [3] - Xinlitai has eight clinical phase III projects and is collaborating with Huawei to build an AI drug development platform, reducing the drug development cycle by 40% [3] - The antibiotic company has a comprehensive supply chain for penicillin and cephalosporins, with a projected net profit increase of 2496.82% year-on-year in Q4 2024, reaching 127 million yuan [3]

Core Viewpoint - The company is celebrating its 40th anniversary in the pharmaceutical industry, marking significant achievements in both generic and innovative drug development, with a clear focus on biopharmaceuticals and internationalization as key strategic directions [2][4][8]. Group 1: Company History and Development - The company was founded in 2001 by Yu Weishi, who aimed to provide affordable and high-quality medicines during a time of rapid growth in the Chinese pharmaceutical market [3]. - Initially focused on generic drug production, the company achieved significant milestones with products like Omeprazole enteric-coated capsules and Ginkgo biloba extract injection, with several products generating annual sales exceeding 1 billion or even 10 billion [3][4]. - By 2012, the company began integrating innovation into its strategy, launching its first Class 1 new drug project and later developing the first domestically produced anti-ED drug [4][5]. Group 2: Research and Development Strategy - The company has established a robust R&D team of over 500 members, collaborating with prestigious institutions to accelerate the translation of research into practical applications [5][6]. - Current R&D strategies focus on innovative drugs targeting cardiovascular diseases, cancer, and infectious diseases, while also developing high-end generic drugs with technical barriers [6][7]. - As of the end of 2024, the company has 42 ongoing research projects, including 21 innovative drugs and 21 generic drugs [4][6]. Group 3: Innovative Drug Pipeline - Several innovative drugs are in the application stage for market approval, including mRNA vaccines and nucleic acid drugs, with significant advancements in clinical trials [7][9]. - The company is actively pursuing breakthroughs in biopharmaceuticals, with a focus on nucleic acid and gene therapy, and aims to have multiple projects entering the application or clinical registration phases annually [7][9]. Group 4: Technological Advancements - The company has invested heavily in new technologies, with R&D expenditures reaching 422 million yuan, accounting for 11.16% of revenue, and has developed eleven major technology platforms [9][10]. - Innovations include breakthroughs in mRNA vaccine technology and AI integration in drug development processes, enhancing efficiency and effectiveness [10][12]. - A strategic partnership with Huawei has been established to advance digital transformation within the pharmaceutical industry [11].

悦康药业集团股份有限公司 2024 年年度股东大会会议资料 悦康药业集团股份有限公司 会议资料 悦康药业集团股份有限公司 2024 年 年度股东大会会议资料 悦康药业集团股份有限公司 2024 年年度股东大会会议资料 目 录 悦康药业集团股份有限公司 为了维护全体股东的合法权益，确保股东大会的正常秩序和议事效率，保证 大会的顺利进行，根据《中华人民共和国公司法》（以下简称"《公司法》"）、 《中华人民共和国证券法》（以下简称"《证券法》"）、《上市公司股东大会 规则》以及《悦康药业集团股份有限公司章程》（以下简称"《公司章程》"） 的相关规定，认真做好召开股东大会的各项工作，特制定本须知： 九、本公司不向参加股东大会的股东发放礼品，不负责安排参加股东大会股 东的住宿等事项，以平等对待所有股东。 悦康药业集团股份有限公司 一、为保证股东大会的严肃性和正常秩序，切实维护股东的合法权益，除出 席会议的股东及股东代表、董事、监事、公司高级管理人员、公司聘任律师及中 介机构外，公司有权依法拒绝其他人员入场。 二、请出席会议的股东及股东代表在会议召开前 20 分钟到达会议现场办理 签到手续。大会工作人员将对出席会议者的身 ...

Investment Rating - The report maintains a "Buy" rating for the company, indicating a positive outlook for future performance [4]. Core Insights - The company achieved a revenue of 27.98 billion RMB in 2024, representing a year-on-year growth of 22.63%. The net profit attributable to shareholders was 6.34 billion RMB, up 47.28% year-on-year [1]. - The innovative drug revenue grew rapidly, reaching 13.89 billion RMB in 2024, a 30.6% increase year-on-year. The company has received approvals for 17 new molecular entity drugs in China and has made significant progress in overseas licensing [2]. - The company is enhancing its technology platforms, including PROTAC, peptides, monoclonal antibodies, and ADCs, with 26 self-developed innovative molecules entering clinical stages [3]. - Revenue projections for 2025, 2026, and 2027 are estimated at 30.84 billion RMB, 34.87 billion RMB, and 39.75 billion RMB, respectively, with expected growth rates of 10.22%, 13.04%, and 14.00% [4]. Summary by Sections Performance Review - In 2024, the company reported a revenue of 27.98 billion RMB, a 22.63% increase from the previous year, and a net profit of 6.34 billion RMB, reflecting a 47.28% growth [1]. Operational Analysis - The innovative drug segment saw a revenue of 13.89 billion RMB, with a 30.6% year-on-year increase. The company has successfully launched 17 new drugs in China and made strides in international licensing agreements [2]. - The company is developing various technology platforms and has 26 innovative molecules in clinical trials, with significant advancements in ADC products [3]. Profit Forecast and Valuation - The company is projected to achieve revenues of 30.84 billion RMB, 34.87 billion RMB, and 39.75 billion RMB in 2025, 2026, and 2027, respectively, with corresponding net profits of 6.95 billion RMB, 7.71 billion RMB, and 8.93 billion RMB [4].

Core Insights - In 2024, Fosun Pharma reported a slight decline in revenue to CNY 41.067 billion, while net profit increased by 16.08% to CNY 2.770 billion, and operating cash flow rose by 31.13% to CNY 4.477 billion [1][2] Financial Performance - Revenue for 2024 was CNY 41.067 billion, a year-on-year decrease of 0.8% - Net profit attributable to shareholders reached CNY 2.770 billion, reflecting a growth of 16.08% - Operating cash flow net amount was CNY 4.477 billion, up 31.13% from the previous year [1][2] Strategic Focus - The company aims to concentrate on the development of innovative drugs and high-value medical devices, transitioning its product structure and strategy [1][2] - Plans to optimize asset structure by divesting non-core and low-efficiency assets, with nearly CNY 3 billion raised from asset sales in 2024 [2] R&D Investment - Total R&D investment for 2024 was CNY 5.554 billion, with CNY 3.644 billion allocated specifically for R&D expenses [3] - The company has established a global open innovation R&D system, focusing on oncology and immune inflammation, and is enhancing core technology platforms [3] International Revenue - Overseas revenue reached CNY 11.297 billion, accounting for 27.51% of total revenue, marking an increase of 8.93% year-on-year [4] - The company has strengthened its international partnerships and quality certifications to support its global market expansion [4] Market Outlook - The company perceives a positive trend in the biopharmaceutical industry, supported by government policies and innovative payment mechanisms [2][5] - There is a growing confidence in the global positioning of China's biopharmaceutical sector, despite current financing challenges [5] AI Integration - The company has launched the PharmAID decision-making platform to enhance operational efficiency and reduce costs [7][8] - Strategic collaborations with AI firms aim to integrate AI into drug development and other operational areas, enhancing research efficiency and success rates [8]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完整性 亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容而產生或因倚賴該等內容而引致 的任何損失承擔任何責任。 二零二五年三月二十六日 於本公告日期，本公司的執行董事為唐陽剛先生 ( 總裁 ) 及徐國祥先生 ( 副董事長及副總裁 ); 本公司的非執行 董事為朱保國先生 ( 董事長 ) 、陶德勝先生 ( 副董事長 ) 、林楠棋先生及邱慶豐先生 ; 而本公司的獨立非執行 董事為白華先生、田秋生先生、黃錦華先生、羅會遠先生及崔麗婕女士。 海外監管公告 本公告乃根據香港聯合交易所有限公司證券上市規則第 13.10B 條而刊發。 茲載列麗珠醫藥集團股份有限公司於深圳證券交易所網站刊發之《麗珠醫藥集團股份有限公司 2024 年年度報告摘要》，僅供參閱。 承董事會命 麗珠醫藥集團股份有限公司 Livzon Pharmaceutical Group Inc. * 公司秘書 劉寧 中國，珠海 * 僅供識別 1 证券代码：000513、01513 证券简称：丽珠集团、丽珠医药 公告编号：2025-018 丽珠医药集团股份有限公司 2 ...

Core Viewpoint - The report highlights the significant advancements and strategic initiatives of Shanghai Fosun Pharmaceutical (Group) Co., Ltd. in the pharmaceutical and medical device sectors, emphasizing innovation, compliance, and market expansion as key drivers for growth in 2024. Company Overview - The pharmaceutical industry is driven by innovation, with the government prioritizing the development of innovative drugs as a new emerging industry [5][6] - The company has maintained a strong position in the industry, ranking 4th in the "2023 Annual Top 100 Chinese Pharmaceutical Industry" list [12] Industry Development Status - The implementation of the "Drug Standard Management Measures" in January 2024 aims to enhance drug quality and safety [8] - Continuous anti-corruption efforts in the medical and pharmaceutical sectors are expected to promote long-term healthy development [8] - The government has introduced policies to support the upgrade of medical equipment, providing new sales opportunities for the medical device industry [9] Business Highlights - The company achieved operating revenue of 41.067 billion yuan in the reporting period, with significant growth in innovative products [26] - The net profit attributable to shareholders increased by 16.08% to 2.770 billion yuan, with a net profit excluding non-recurring gains and losses rising by 15.10% [26] - The company has focused on innovation, with R&D investment totaling 5.554 billion yuan, of which 3.644 billion yuan was dedicated to R&D expenses [27] Product Development - The company has received approvals for 16 indications across 7 innovative drugs and biosimilars during the reporting period [28] - The innovative PD-1 monoclonal antibody, Hanshu (SruLi), received approval for a new indication in China [29] - The company has successfully launched several products in international markets, including the biosimilar trastuzumab in the US and Canada [29][30] Global Expansion - The company has established a strong global presence, with a commercial team of over 1,000 people covering markets in the US, Africa, and other regions [42] - The company has formed strategic partnerships to enhance its international market access and product commercialization [38][39] Compliance and Regulatory Environment - The company is committed to adhering to regulatory requirements and enhancing compliance in response to the ongoing anti-corruption initiatives in the pharmaceutical industry [25] - The company has implemented measures to ensure the quality and safety of its products, aligning with national standards and regulations [41]