9月10日，由36氪主办的2025年36氪产业未来大会在中国厦门盛大启幕。本次大会重磅携手商务部主办的"中国国际投资贸易洽谈会"，以"精耕时代，潮涌嘉 禾"为核心主题，倾力打造一场兼具国家高度、产业深度与市场热度的高规格、高价值、高影响力产业盛典。 大会紧密锚定国家战略导向与产业发展前沿，聚焦人工智能、低空经济、先进制造、新能源、大消费五大核心赛道，汇聚行业顶尖力量共商发展路径、擘画 产业未来。在为期两天的议程中，大会以"产业协作链条"为逻辑主线，重点聚焦"政、资、产"三方协同机制，深入探讨如何打破壁垒、整合资源，精准破解 产业发展中的痛点堵点与瓶颈制约。 以下为圆桌内容，经36氪整理编辑： 海若镜：大家好，我是36氪的海若镜。今天非常高兴能有机会与大家探讨"医疗产业趋势与科技创新"，也非常感谢大家能够坚持到最后的圆桌讨论环节。从 今天的议程排序或许可以看出，医疗产业并非当下最火热的赛道，但它无疑是必不可少的。因为"让天下没有治不好的病，没有吃不起的药"，是每个人都会 关心的话题，也是我认为医疗产业能够穿越周期的底气所在。 今天我们也非常荣幸地邀请到了四位业界专家，与我们一同探讨这个主题。四位嘉宾对于医疗产业 ...

Summary of the Conference Call for Tigermed (泰格医药) Company Overview - Tigermed is a leading clinical Contract Research Organization (CRO) in China, established in 2004, focusing on clinical trials and related services, including registration, medical writing, and pharmacovigilance [4][5]. Industry Insights - The domestic clinical CRO sector has shown significant performance improvements, driven by the recovery of demand for innovative drugs and the impact of favorable policies [3]. - The Chinese biopharmaceutical industry is entering a phase of original innovation, with increasing global recognition of domestic data and a higher proportion of external licensing pipelines [2][7]. Financial Performance - In the first half of 2024, Tigermed's revenue decreased by 3% year-on-year to 3.25 billion yuan, and non-recurring net profit fell by 67% to approximately 200 million yuan [2][6]. - Despite the decline, the impact of low-price orders is gradually dissipating, and a return to double-digit growth in revenue and profit is expected in the coming year [2][6]. Market Dynamics - The Chinese clinical CRO market is fragmented, with Tigermed holding a market share of approximately 13%, expected to rise to 15% [10]. - The demand for overseas orders, which typically offer higher profit margins, is crucial for sustaining growth in the second and third quarters [11]. Business Development - Tigermed has a broad project layout, with over 400 domestic projects and 200 international projects, primarily in the US, Japan, South Korea, and Australia [12][21]. - The company has seen a 7% year-on-year increase in new orders for 2024, with a continued acceleration in the first half of the year [22]. Strategic Initiatives - The company is expanding globally through acquisitions and the establishment of local teams, enhancing its service capabilities from clinical trials to imaging analysis [21]. - The domestic biopharmaceutical industry is experiencing a diversification of funding sources, with industrial funds and state-owned capital becoming significant players [9][8]. Future Outlook - The overall performance of the clinical trial services segment is expected to recover, with a projected increase in orders as early research in China rebounds [20][22]. - The company anticipates that the clinical CRO and early-stage CRO industries will show strong growth, contingent on the recovery of orders [22]. Additional Insights - The SMO (Site Management Organization) business has seen significant growth, although it faces some price competition and personnel surplus issues [17][18]. - The tree child business segment has been a strong contributor to profits, maintaining steady growth [16]. This summary encapsulates the key points from the conference call, highlighting Tigermed's current position, market dynamics, financial performance, and future outlook in the clinical CRO industry.

Group 1 - The core viewpoint of the article emphasizes the importance of timely and relevant research reports in identifying investment opportunities, particularly in the pharmaceutical and technology sectors [1] - The article highlights that the dual drivers of BD overseas expansion and the release of medical insurance will lead to significant growth in innovative drugs, with a projected leading increase in the pharmaceutical sector by H1 2025 [1] - Six potential high-growth stocks have been identified by institutions as key investment targets in the pharmaceutical sector [1] Group 2 - The article discusses the dual drivers of robotics and commercial aerospace, indicating a comprehensive layout in harmonic drives, dexterous hands, and sensors, which positions companies for high growth [1] - Institutions forecast a compound annual growth rate (CAGR) of over 30% for net profits from 2025 to 2027 in the technology sector [1]

Core Viewpoint - The company has demonstrated strong sales growth for its product, Naisfukang, following capacity expansion, leading to an upward revision of sales guidance and reflecting confidence in clinical data and commercialization capabilities [1][2] Group 1: Sales Performance - In the first half of 2025, the company's revenue increased by 48% year-on-year to 446 million RMB, with Naisfukang sales growing by 81% to 303 million RMB [1] - After capacity constraints were resolved, Naisfukang's sales surged to 522 million RMB in August, contributing to a total sales figure of 825 million RMB from January to August [1] - The management has raised the annual sales target for Naisfukang to 1.2-1.4 billion RMB, with total product sales expected to reach 1.6-1.8 billion RMB [1] Group 2: Financial Outlook - The company expects to achieve operational breakeven in the second half of 2025, earlier than previously anticipated [1] - The net loss for the first half of 2025 narrowed significantly by 61% to 250 million RMB, attributed to strong sales performance and stable SG&A expense ratios [1] Group 3: Product Pipeline and Future Prospects - The company is set to commercialize its third product, Aicuo Mod, which is anticipated to be approved in the first half of 2026 for ulcerative colitis, with a projected peak sales of 5 billion RMB [2] - The self-developed pipeline includes EVER001, targeting autoimmune kidney diseases, with global sales peak expected to exceed 10 billion RMB [2] - The company has revised its revenue forecasts for 2026-2027 upwards by 16-18%, reflecting optimism in operational expense ratios and potential catalysts in the pipeline [2] Group 4: Valuation and Investment Recommendation - The target price has been raised to 84 HKD from 72.5 HKD, corresponding to a 2.1 times revenue peak sales multiple [2] - The current valuation remains attractive, with multiple catalysts expected in the second half of 2025 and 2026, including product approvals and commercialization efforts [2]

Group 1 - Pharmaceutical stocks continue to rise, with notable increases in companies such as BeiGene (up 7.87%), Clover Biopharma (up 6.03%), and Tigermed (up 5.03%) [1] - BlackRock increased its stake in 3SBio by acquiring approximately 47.6 million shares at a price of HKD 30.1096 per share, totaling around HKD 14.33 billion, raising its ownership to 5.1% [1] - The overall performance of Hong Kong pharmaceutical companies in the first half of the year has been robust, with companies like Hengrui Medicine and Hansoh Pharmaceutical reporting record high revenues and profits [1] Group 2 - The pharmaceutical sector has shown strong stock performance in the first half of the year, driven by continuous business development (BD) overseas, excellent clinical data, and supportive policies [2] - The innovative drug sector is experiencing rapid sales growth, with several key products being approved and included in medical insurance, leading to increased domestic sales [2] - Companies like BeiGene and Hutchison China MediTech have successfully commercialized their products overseas, contributing significantly to revenue growth [2]

Core Viewpoint - Hansoh Pharmaceutical reported strong financial performance for the first half of 2025, with significant growth in revenue and net profit driven by innovative drug sales and licensing income [1][2]. Financial Performance - In the first half of 2025, Hansoh Pharmaceutical recorded revenue of 7.434 billion yuan, a year-on-year increase of 14.3% - The net profit attributable to shareholders was 3.135 billion yuan, reflecting a year-on-year growth of 15.0% - Innovative drug sales and licensing income amounted to 6.145 billion yuan, accounting for 82.7% of total revenue [1]. Expense Analysis - Sales expenses reached 1.818 billion yuan, up 5.6% year-on-year - Research and development expenses were 1.441 billion yuan, increasing by 20.5% year-on-year - Management expenses decreased to 343 million yuan, down 3.1% year-on-year [1]. Business Segmentation - Revenue from different therapeutic areas included: oncology (4.531 billion yuan, 60.9%), infectious diseases (735 million yuan, 9.9%), central nervous system (768 million yuan, 10.4%), and metabolism/others (1.400 billion yuan, 18.8%) - The company focuses on oncology while also developing products in infectious diseases, central nervous system, and metabolism, creating a robust product matrix [1]. Clinical Pipeline - As of the mid-2025 report, the company has over 40 candidate innovative drug pipelines and is conducting more than 70 clinical trials, including 8 candidates entering clinical trials for the first time and 3 major products in phase 3 trials - The company is actively expanding indications for existing major products and advancing preclinical pipelines [2]. Business Development Opportunities - During the reporting period, the company received a confirmed upfront payment of 112 million USD from Merck, contributing to collaboration revenue - A collaboration agreement with Regeneron for HS-20094 was established, with an upfront payment of 80 million USD received, and a potential total transaction value of 1.93 billion USD [2]. Profit Forecast - The company expects net profits attributable to shareholders for 2025-2027 to be 5.021 billion, 5.567 billion, and 6.355 billion yuan, with year-on-year growth rates of 14.9%, 12.9%, and 12.1% respectively - Corresponding price-to-earnings ratios are projected to be 40, 35, and 31 times [3].

Investment Rating - The report maintains a "Buy" rating for the company [6] Core Insights - The company achieved a revenue of 15.76 billion yuan in H1 2025, representing a year-over-year growth of 15.88%, and a net profit attributable to shareholders of 4.45 billion yuan, up 29.67% year-over-year, slightly exceeding expectations due to a significant increase in licensing income [1][2] Summary by Sections Revenue and Profit Growth - The company's innovative drug sales and licensing income reached 9.56 billion yuan in H1 2025, accounting for 60.66% of total revenue, with innovative drug sales alone contributing 7.57 billion yuan. The clinical value of innovative drugs such as Rivoraxaban and Darsilene has been recognized by doctors, leading to rapid revenue growth [2] Business Development (BD) Achievements - In H1 2025, the company secured three external licensing agreements, including a 15 million euro upfront payment from Merck for an oral GnRH receptor antagonist, a 200 million USD upfront payment from MSD for an Lp(a) inhibitor, and a 500 million USD upfront payment from GSK for 12 new drugs. The total potential milestone payments and sales royalties from these agreements could reach up to 17.7 billion USD [3] Operational Efficiency - The company's management, sales, and R&D expense ratios were 8.15%, 27.85%, and 20.48% respectively, showing a year-over-year decrease of 0.48pp, 1.11pp, and 1.86pp, indicating effective cost control and improved operational efficiency. The net operating cash flow increased significantly by 41.80% to 4.30 billion yuan, reflecting strong cash generation capabilities [3] Profit Forecast and Valuation - The company is recognized as a leading player in China's innovative drug sector, with continuous investment in R&D. The net profit forecasts for 2025-2027 have been raised to 9.05 billion yuan, 9.48 billion yuan, and 10.60 billion yuan respectively, with corresponding P/E ratios of 48, 45, and 41 [4][5]

Core Viewpoint - The innovative drug sector has shown strong performance in 2023, with related ETFs reaching new highs, and analysts are optimistic about the sector's long-term investment value, particularly looking towards 2025 as a pivotal year for recovery in the pharmaceutical industry [1][2]. Policy Support - The Chinese government has released multiple favorable policies since 2025 to optimize drug procurement and support innovative drugs, marking a period of significant policy dividends for the innovative drug sector [2]. - Specific measures include 16 initiatives aimed at supporting high-quality development of innovative drugs, focusing on R&D support, integration with medical insurance, clinical application, and diversified payment capabilities [2]. - The establishment of a "newly listed drug initial pricing mechanism" has been confirmed, allowing high-quality innovative drugs to achieve returns that align with their high investment and risk levels [2][3]. Market Dynamics - The introduction of the initial pricing mechanism is expected to provide innovative drug manufacturers with greater pricing flexibility and a more efficient listing process, leading to faster cash flow returns for high-quality innovative drugs [3]. - Nearly 100 domestic innovative drugs are currently in the approval process, which will benefit from the new pricing mechanism upon approval [3]. Business Development (BD) as a Key Driver - The trend of Chinese innovative drugs going global has accelerated, with significant BD transactions occurring, including a $60 billion deal between 3SBio and Pfizer, and a potential $12.5 billion deal between Hengrui Medicine and GSK [4]. - In the first half of 2025, 50 BD projects were completed, with total disclosed transaction amounts exceeding $48.4 billion, setting a historical record for innovative drug exports [4][5]. Global Recognition and Future Outlook - The global market is increasingly recognizing the R&D capabilities of Chinese biopharmaceutical companies, with a notable increase in the number and value of BD transactions involving Chinese firms [5][6]. - Analysts remain optimistic about the innovative drug sector, highlighting that the current valuation of Chinese biotech companies is significantly lower than their U.S. counterparts, indicating a potential undervaluation and room for growth [6].

Core Insights - The enthusiasm for domestic innovative drug development remains strong, with continuous growth in innovative outcomes [1] - In 2024, six domestic innovative drugs are expected to receive their first approvals in overseas markets [1] - In clinical research, the number of clinical trial registrations for domestic innovative drugs surpassed that of the United States in 2023, ranking first globally [1] - The number of first-in-class (FIC) innovations ranks second globally, only behind the United States [1] - Domestic innovative drugs hold a high proportion in both mature and FIC target therapies [1] - The quality of domestic innovations is being validated through head-to-head clinical results of drugs like Zebutine and AK112 in overseas markets [1] - The recognition of Chinese data is increasing at various global conferences [1] - Dongwu Securities indicates that the current logic of the innovative drug industry has shifted to focus on business development (BD) for international expansion [1] - More domestic innovative pharmaceutical companies are utilizing diverse methods such as licensing and joint development to push their self-developed drugs into international markets, aiming for breakthroughs in mature pharmaceutical markets like Europe and the U.S. [1] - This new model of "local innovation to global monetization" is reshaping the industry landscape [1] - The innovative drug index still has significant room for growth compared to its peak in 2021 [1] - The Hong Kong Stock Connect Medical ETF (520510) has been launched, tracking the Hong Kong Stock Connect medical theme index, which covers three major segments of the medical sector [1] - The ETF has over 30% weight in CXO, over 20% in AI medical, and nearly 50% in innovative drugs, and is expected to benefit from trends such as anti-involution, innovative drug internationalization, and the AI technology revolution [1]

Group 1 - The core viewpoint of the news is that BeiGene, a leading innovative drug company in the A-share market, reported significant financial growth in the first half of 2025, marking its first half-year profit since its listing [1] - In the first half of 2025, BeiGene achieved total revenue of 17.518 billion yuan, representing a year-on-year increase of 46.0%, with product revenue reaching 17.360 billion yuan, up 45.8% year-on-year [1] - The company reported an operating profit of 799 million yuan and a net profit attributable to shareholders of 450 million yuan [1] - BeiGene updated its revenue guidance, expecting full-year revenue for 2025 to be between 35.8 billion yuan and 38.1 billion yuan [1] - Dongwu Securities noted that both the entire pharmaceutical sector and the innovative drug sub-sector have a market capitalization in A-shares and H-shares that is lower than that in the US stock market, indicating potential structural growth opportunities for domestic innovative drug companies [1] Group 2 - The Hong Kong Stock Connect Medical ETF (520510) focuses on three main lines: innovative drugs, CXO, and AI healthcare [2] - The Hang Seng Medical ETF (159892) is highly focused on the innovative drug sector and has a significant holding in BeiGene [3]