一水 发自 凹非寺 量子位 | 公众号 QbitAI 用意念操控万物的"脑机接口"，就这样离我们更近了？！ 据央妈最新报道， 我国已成功开展首例侵入式脑机接口临床试验 —— 一位因意外事故导致四肢截肢的男子，现在 仅凭意念 就能玩五子棋游戏、发短信等等。 这项研究由中国科学院脑科学与智能技术卓越创新中心，联合复旦大学附属华山医院以及相关企业合作完成。 其成功标志着，除了马斯克的Neuralink，我国成为 全球第二个 进入侵入式脑机接口技术临床试验阶段的国家。 而且所植入的神经电极目前全球尺寸最小、柔性最强—— 植入体仅硬币大小 （为Neuralink产品1/2） ，超柔性电极约为头发丝的1/100 （超过Neuralink百倍） 。 对于这一新进展，网友们除了纷纷感叹科幻照进现实，更有脑洞大开的同学表示： 以后能直接把课本植入进去了 （不想学可以直说~doge） 幻想归幻想，但目前已经能确定下一步研究方向—— 短期会尝试让受试者使用机械臂，使他可以在物理生活中完成抓握、拿杯子等操作。 长期还可能涉及对复杂物理外设进行控制，例如对机器狗、具身智能机器人等智能设备的控制，拓展生活边界。 而以上这些目标的实现，均 ...

一水 发自 凹非寺 量子位 | 公众号 QbitAI 用意念操控万物的"脑机接口"，就这样离我们更近了？！ 据央妈最新报道， 我国已成功开展首例侵入式脑机接口临床试验 —— 一位因意外事故导致四肢截肢的男子，现在 仅凭意念 就能玩五子棋游戏、发短信等等。 这项研究由中国科学院脑科学与智能技术卓越创新中心，联合复旦大学附属华山医院以及相关企业合作完成。 其成功标志着，除了马斯克的Neuralink，我国成为 全球第二个 进入侵入式脑机接口技术临床试验阶段的国家。 而且所植入的神经电极目前全球尺寸最小、柔性最强—— 植入体仅硬币大小 （为Neuralink产品1/2） ，超柔性电极约为头发丝的1/100 （超过Neuralink百倍） 。 长期还可能涉及对复杂物理外设进行控制，例如对机器狗、具身智能机器人等智能设备的控制，拓展生活边界。 而以上这些目标的实现，均离不开团队在脑机接口 软硬件方面所取得的突破 —— 用上了半导体加工工艺 作为一种侵入式脑机接口 （需要通过微创手术将电极植入大脑） ，团队在硬件设计上核心追求一个目标： 最大程度降低对脑组织的损伤 。 对于这一新进展，网友们除了纷纷感叹科幻照进现实，更有 ...

记者 黄海华 中国首例侵入式脑机接口临床试验受试者的生活，正在发生改变——两个多月来，他用意念下象 棋，和家人玩赛车游戏，"脑控"效率与普通人控制电脑触摸板相近。其乐融融中，他对于"一个家的幸 福"有了更多感悟：一家人在一起共同做一件事，就是幸福。 从非侵入式到半侵入式再到侵入式，对于中国脑机接口领域而言，这不啻一个里程碑。我国成为继 美国之后全球第二个开展侵入式脑机接口临床试验的国家，且多项指标超越马斯克创立的脑机接口公司 Neuralink。 地处上海的中国科学院脑科学与智能技术卓越创新中心（以下简称"脑智卓越中心"）联合复旦大学 附属华山医院，与沪上相关企业合作完成了这一创举。对于正在建设有全球影响力科技创新高地的上海 而言，该成果为脑机接口这一未来产业提供了"上海方案"。 "全球首创"获国际同行认可 相比马斯克的脑机接口公司，"上海方案"优势在哪里？ "在同一技术赛道上，我们的电极又细又柔，粗细仅相当于一根头发丝的百分之一；柔软程度仅为 细胞间的作用力。"脑智卓越中心研究员赵郑拓介绍，这一全球最小尺寸的神经电极，仅为Neuralink所 使用电极的1/5到1/7，柔性却是其百倍。这使得脑细胞几乎"意识 ...

Core Insights - Neuralink has successfully enabled a monkey to "see" virtual objects through its brain-machine interface technology, which has potential applications for helping blind individuals perceive the world [1] - The device, named Blindsight, stimulates areas of the brain associated with vision, tricking the monkey's visual system into recognizing non-existent objects [1] - This marks the first public demonstration of Blindsight's experimental results, highlighting the cutting-edge nature of brain device development aimed at treating traditionally difficult medical conditions like blindness [1] Summary by Sections Technology and Innovation - Blindsight is a brain-implanted chip designed to simulate eye functions and directly stimulate the visual cortex [1] - During experiments, the monkey looked at the location of a virtual object over two-thirds of the time, indicating it perceived the non-existent target [1] Future Applications - The short-term goal of Blindsight is to assist blind individuals in seeing, while the long-term vision includes achieving "superhuman vision," such as the ability to see infrared light [2] - Neuralink is also advancing another project aimed at helping paralyzed individuals interact with computers using their thoughts [2] Human Trials - Currently, five humans have received Neuralink implants, with three implanted in 2024 and two in 2025, and some participants reportedly use the brain-machine device for up to 60 hours per week [2]

2025.06. 14 本文字数：1492，阅读时长大约2分钟 作者 | 一财区域 赵郑拓和李雪团队的 侵入式脑机接口系统是国内唯一获得了注册型检报告且可以长期稳定采集到单 神经元Spike信号的脑机接口系统，其毫秒级、单神经元水平的神经信号捕获特性为应用提供了良好 的神经电信号数据基础。 在手术友好程度方面，脑智卓越中心研制的植入体直径26mm、厚度不到 6mm，是全球最小尺寸的脑控植入体，仅硬币大小，为Neuralink产品1/2。因此不需要整体贯穿颅 骨，只需要在大脑运动皮层上方的颅骨上"打薄"出一块硬币大小的凹槽用以镶嵌设备，再在凹槽中打 一个5毫米的穿刺孔。采用神经外科微创术式，在有效降低手术期风险的同时，显著缩短术后康复周 期。基于成熟外科技术构建的完整操作体系，其标准化的操作流程更利于在各级医疗机构神经外科开 展规模化应用。 超柔性电极尺寸极小，仅约头发丝的1/100 此外，有别于Neuralink较多的冗余设计，该侵入式脑机接口系统是在神经科学原理指导下设计的， 可以通过较少数量的植入电极实现跟Neuralink相似的控制水平。该低冗余量设计尽量减少对患者带 来植入损伤，让患者收益风险比最高。 ...

近日，中国科学院脑科学与智能技术卓越创新中心联合复旦大学附属华山医院，与相关企业合 作，成功开展了我国首例侵入式脑机接口的前瞻性临床试验。该成果标志着 我国在侵入式脑 机接口技术上成为全球第二个进入临床试验阶段的国家。 受试者是一位因高压电事故导致四肢截肢的男性。自2025年3月植入该脑机接口设备以来，系 统运行稳定， 仅用2—3周的训练，他便实现了下象棋、玩赛车游戏等功能，达到了跟普通人 控制电脑触摸板相近的水平。 未来，这一系统将有望为脊髓损伤、截肢等患者群体，通过运 动功能替代技术实现生存质量改善。 全球最小尺寸、柔性最强的神经电极 △超柔性电极尺寸极小，仅约头发丝的1/100 △植入体直径26mm、厚度不到6mm，是全球最小尺寸的脑控植入体，仅硬币大小 在手术友好程度方面，脑智卓越中心研制的植入体直径26mm、厚度不到6mm， 是全球最小 尺寸的脑控植入体， 仅硬币大小，为Neuralink产品1/2。因此不需要整体贯穿颅骨，只需要 在大脑运动皮层上方的颅骨上"打薄"出一块硬币大小的凹槽用以镶嵌设备，再在凹槽中打一个 在颅骨上开5毫米的穿刺孔。采用神经外科微创术式，在有效降低手术期风险的同时，显著缩 ...

Core Insights - The article highlights the successful initiation of China's first invasive brain-computer interface (BCI) clinical trial, marking a significant advancement in the field, making China the second country after the United States to enter this phase [1] Group 1: Clinical Trial Details - The clinical trial was conducted by the Chinese Academy of Sciences' Brain Science and Intelligent Technology Center in collaboration with Fudan University Huashan Hospital, focusing on a male subject who lost all four limbs due to an electrical accident [1] - The implanted BCI device has shown stable operation since its implantation in March 2025, with no infections or electrode failures reported over a month [1] - The subject achieved functionalities such as playing chess and racing games within 2-3 weeks of training, demonstrating control comparable to that of a typical user with a computer touchpad [1] Group 2: Technological Advancements - The BCI system developed by the Zhao Zhengtuo and Li Xue teams features the world's smallest and most flexible neural electrodes, with a cross-sectional area only 1/5 to 1/7 that of Neuralink's electrodes, and flexibility exceeding Neuralink's by a factor of 100 [2] - This ultra-flexible electrode allows for high-density, large-area, and long-term stable neural signal acquisition, addressing key challenges in tissue compatibility and bandwidth limitations for implanted BCIs [2] Group 3: Surgical and Operational Efficiency - The BCI system is the only one in China with a registered report that can stably capture single-neuron spike signals, providing a solid data foundation for applications [3] - The device's dimensions are 26mm in diameter and less than 6mm in thickness, making it the smallest brain-controlled implant globally, requiring only a small recess in the skull for implantation, thus reducing surgical risks and recovery time [3] - The standardized operational procedures based on mature surgical techniques facilitate scalable applications in various medical institutions [3] Group 4: Future Applications - The BCI system is designed to achieve similar control levels as Neuralink with fewer implanted electrodes, minimizing patient risk while maximizing benefits [5] - Prior to human trials, the system's safety and functionality were validated in non-human primates, where it successfully controlled computer cursor movement through neural activity [5] - Future plans include enabling the subject to control robotic arms for physical tasks, expanding the potential for interaction with complex devices like robotic dogs and intelligent agents [5]

Core Viewpoint - China's first prospective clinical trial of an invasive brain-computer interface (BCI) has been successfully conducted, making it the second country globally to enter the clinical trial phase after the United States [1] Group 1: Clinical Trial Details - The clinical trial's subject is a 37-year-old male who lost his limbs due to a high-voltage accident. Since the implantation of the BCI device in March, the system has operated stably without infections or electrode failures for over a month [3] - The subject has achieved a level of control over a computer touchpad comparable to that of a normal person, allowing him to play chess and racing games using only his thoughts after 2-3 weeks of adaptive training [3] Group 2: Technological Advancements - The implanted device is the smallest brain-controlled implant globally, measuring 26mm in diameter and less than 6mm in thickness, which is half the size of Neuralink's product [8] - The flexible neural electrodes developed by the research team are 1/5 to 1/7 the cross-sectional area of those used by Neuralink, providing better compatibility with brain tissue and reducing damage [5] Group 3: Research and Development - The research team has established a comprehensive approach to BCI research, covering various aspects such as motion perception, neural function repair, decoding algorithms, and wireless system development since 2022 [5] - The dynamic optimization of the neural decoder has been achieved through an online learning framework, allowing real-time motion decoding and overcoming the limitations of traditional static decoding models [9] Group 4: Future Prospects - The BCI system is expected to improve the quality of life for patients with complete spinal cord injuries, double upper limb amputations, and amyotrophic lateral sclerosis by enabling them to control external devices [12] - Future trials will aim to allow the subject to use robotic arms for physical tasks, expanding the potential applications of the technology [12]

Core Insights - The article highlights the significant progress in brain-machine interface (BMI) technology, particularly focusing on China's first invasive BMI clinical trial, marking a milestone in the medical application of this technology [1][2][11] - The Chinese research team has developed the world's smallest and most flexible neural electrodes, which are now in clinical trials, positioning China as the second country after the United States to enter this phase [1][5] Group 1: Clinical Trial Details - The invasive BMI clinical trial was successfully conducted by a collaboration between the Chinese Academy of Sciences and Fudan University, with the first subject being a male patient who lost his limbs due to an electrical accident [2][11] - The system has shown stable operation since its implantation in March 2025, with no infections or electrode failures reported, allowing the patient to perform tasks like playing chess and racing games within 2 to 3 weeks of training [4][10] Group 2: Technological Advancements - The neural electrodes developed by the Chinese team have a cross-sectional area that is 1/5 to 1/7 of those used by Neuralink, with flexibility exceeding Neuralink's by over 100 times, minimizing damage to brain tissue [5][8] - The implanted BMI system is capable of long-term stable collection of single-neuron spike signals, providing a solid data foundation for applications in neuroprosthetics [5][7] Group 3: Surgical and Operational Innovations - The BMI system features a compact design with a diameter of 26mm and a thickness of less than 6mm, allowing for a minimally invasive surgical procedure that reduces risks and recovery time [7][11] - The surgical procedure utilized advanced imaging techniques to create a detailed 3D model of the patient's brain, ensuring precise electrode placement [11][13] Group 4: Future Applications and Research Directions - The research team aims to expand the functionality of the BMI system to enable patients to control robotic arms and other external devices, enhancing their quality of life [11][12] - Future developments may incorporate machine learning and artificial intelligence to interpret more complex signals, potentially allowing for communication through thought [11][12]

中国战略新兴产业融媒体记者 卜文娟 2030年至2040年间，全球脑机接口仅在医疗领域应用的潜在市场规模有望达400亿至1450亿美元。当 前，我国脑机接口产业已涌现大量初创企业。相关专利申请量、融资事件数量及金额均有大幅增长，并 有百家企业的产品进入临床阶段。 近日，"科技狂人"埃隆·马斯克旗下脑机接口公司Neuralink宣布完成6.5亿美元（约合人民币43亿元）新 一轮融资，投前估值飙升至90亿美元（约合人民币650亿元）。 资本市场热情高涨。同时在政策与技术持续催化下，我国脑机接口行业进入爆发前夜，对于众多失能患 者来说，曾经以为遥不可及的康复梦想已是触手可及——瘫痪患者恢复运动功能，失语者重获语言能 力，甚至让盲人重新拥抱光明。 脑机接口临床推进 脑机接口已从曾经的科学幻想和前沿探索，逐步演变为一项具有深远潜力的技术革新。从早期的基础研 究，到如今在医疗、科研等领域的初步应用，脑机接口正以其独特的魅力，吸引着全球科研人员和产业 界的目光。 历经30年发展，当下的脑机接口技术路线主要分为非侵入式、半侵入式和侵入式。据了解，半侵入式与 侵入式脑机接口技术聚焦医疗领域，凭借其直接与大脑神经组织交互的特性， ...