这一技术的核心创新在于将组织中的蛋白质先锚定、再膨胀、再扫描：第一步，锚定蛋白质，即用锚定 试剂将蛋白质锚定在水凝胶网络中，避免蛋白质扩散并去除干扰物质；第二步，使组织线性膨胀3至7倍 且保持结构完整；第三步，给蛋白"拍高清照"，即原位酶解与质谱成像；第四步，通过自主开发的计算 流程解析数据，自动识别组织结构与特异性蛋白。 为验证iPEX的性能与应用价值，研究团队在多种组织、类器官及疾病模型中开展实验。邹贻龙介绍， 在小鼠视网膜研究中，iPEX仅凭蛋白质表达谱就重构出清晰的组织分层，识别出不同细胞层的特异性 蛋白质，这是传统技术无法实现的。此外，研究团队还在小鼠小脑、小鼠肠道、人源脑类器官、小鼠肝 脏组织等样本中展开测试，验证了iPEX的通用性。 "未来，iPEX技术有望在基础研究中助力科学家直接观察蛋白质在精细组织中的分布规律，在临床转化 层面有望为阿尔茨海默病等疾病的早期诊断与治疗提供新路径，为生命科学研究开辟更广阔的视 野。"邹贻龙表示。（记者刘园园，西湖大学供图） 记者11月13日获悉，西湖大学生命科学学院特聘研究员邹贻龙团队与基里尔·皮亚特克维奇（Kiryl D. Piatkevich）团队合作研发 ...

Core Viewpoint - The research institute has developed key technologies for the efficient extraction of strategic rare metals from complex zinc-based materials, addressing industry challenges related to low recovery rates, lengthy processes, and high costs [1] Group 1: Technology Development - The newly developed technologies include indium directional leaching-direct extraction, germanium material maturation leaching-hydrochloric acid regeneration, and gallium-germanium synergistic extraction-cyclone electrolysis [1] - These innovations enable the efficient and clean extraction of rare metals such as indium, germanium, and gallium [1] Group 2: Industry Impact - The technologies have been successfully applied in several enterprises, including Southern Nonferrous Metals Group, Yusheng Germanium Industry, and Danxia Smelting Plant, significantly improving the recovery rates of indium, germanium, and gallium [1] - The advancements contribute to resource recycling and enhance the value of the industrial chain [1] Group 3: Future Directions - The research team plans to continue strengthening core technology development to promote the transformation and upgrading of the nonferrous metal industry towards higher value and greener practices [1]

将重塑材料、器件与信息体系的根基 原子级制造，就是以原子为原料，制造所需的材料和器件产品。"原子级制造是通过对原子的规模化精 准操控，实现原子尺度结构或原子精度加工。它的独特价值在于，'原子'成为可编程的制造单元。"会 议召集人之一、华南师范大学教授赵纪军表示，原子级制造是先进制造技术向极微观深入发展的必然趋 势，也是我国构筑未来产业竞争优势的重要战略选择。 也许有一天，人类可以精确地操控原子，让物质和材料合成摆脱对体系和配方的依赖，从而按照需求自 由定制。这项听上去有些科幻的技术，正一步步向现实迈进。 "原子级制造不仅是材料科学与制造工程的交汇点，更是人类认识和重构物质的全新方式。"11月11日至 14日，南京大学与施普林格·自然出版集团联合主办的"原子级制造：前沿与应用"国际会议在南京大学 举行。会议发起人之一、南京大学原子制造研究院院长宋凤麒教授介绍，如何将原子垒砌成"人工分 子"，继而制造出新材料、新结构、新产品，正在成为全球科学家改造物质世界的热门探索。 此次会议吸引了来自全球的500余位学者、专家及产业代表参加。多位与会学者表示，原子级制造作为 面向未来的重要战略技术，正在重塑材料科学、器件物理与 ...

Core Insights - The discovery of hot Jupiters, such as 51 Pegasi b, challenges traditional theories of planet formation and evolution, leading to a reevaluation of planetary systems [3][5][6] - Recent research indicates that approximately 60% of hot Jupiters migrate to their host stars within tens of millions of years, while about 40% appear over a timescale of millions to billions of years [7][8] Group 1: Hot Jupiter Characteristics - Hot Jupiters are gas giants similar in size to Jupiter but orbit very close to their host stars, resulting in extremely high surface temperatures [3][4] - The formation of hot Jupiters contradicts the classical "snow line" theory, which suggests that gas giants should form far from their stars [2][3] Group 2: Migration Theories - Three main hypotheses explain the migration of hot Jupiters: disk migration, scattering migration, and long-term chaotic evolution [5][6] - Disk migration suggests that gas giants lose energy and move closer to their stars within a few million years, while scattering migration occurs through interactions with other planets over about 100 million years [5][6] Group 3: Research Findings - The study analyzed 123 hot Jupiters and found a segmented decline in their occurrence rate as host star age increases, with a notable inflection point around 2 billion years [7][8] - The research team aims to create a comprehensive timeline of planetary system evolution and understand the underlying mechanisms driving the formation of various planetary populations [8][9]

Core Insights - Guangdong is accelerating the construction of a strong provincial innovation system during the "14th Five-Year Plan" period, focusing on enhancing the supply capacity of original innovations and promoting the synergy between technological and industrial innovations [1][3]. Innovation Achievements - The "Shenzhen-Hong Kong-Guangzhou" innovation cluster has achieved the highest global innovation index [2]. - R&D expenditure in Guangdong has surpassed 510 billion yuan, maintaining its leadership nationwide [2]. - The province has cultivated nine trillion-yuan industrial clusters, with the core AI industry exceeding 220 billion yuan, accounting for approximately one-third of the national total [2]. - Guangdong ranks first in the number of high-value invention patents and high-tech enterprises in the country [2]. Open Innovation Ecosystem - The construction of the Cold Spring Ecosystem Research Facility in Nansha is progressing, which will enhance marine science research and support the development of the Guangdong-Hong Kong-Macao Greater Bay Area as an international technology innovation center [4][6]. - Guangdong has established 26 key innovation platforms along the Greater Bay Area's technology innovation corridors, with a significant increase in cross-border collaboration and patent applications [5][6]. Foundation of Innovation - Guangdong is strengthening its foundational research capabilities, with over one-third of provincial R&D funds allocated to basic research [7][8]. - The province has initiated the "卓粤" plan to enhance basic research and has established a multi-faceted funding system to support it [7][8]. Technological Advancements - The collaboration between Kingmed Diagnostics, Tencent, and Guangzhou Medical University has led to the development of the DeepGEM pathology model, which predicts lung cancer gene mutations with high accuracy [9]. - The AI industry in Guangdong is rapidly growing, with the core industry scale expected to exceed 220 billion yuan by 2024 [9][10]. Future Directions - Guangdong plans to enhance strategic orientation and systematic planning in major platform construction, key technology breakthroughs, and application of research outcomes to further strengthen its position as a technology innovation powerhouse [10][11].

"本次实验系统验证了新技术对不同卫星频段数据传输效率的提升能力。同时，整个传输过程信号稳定，误码率极低，通信质量优 异。"空天院研究员黄鹏说，此次实验的成功，也标志着我国在X频段和Ka频段的星地数据传输速率，刷新了已知的最高纪录。 黄鹏表示，本次实验充分验证了高阶调制解调技术的应用价值，目前该技术即将应用于实际卫星数据接收任务，对于未来有效解决 星地传输带宽不足问题、提升我国卫星应用效能具有重要意义。 星地之间的数据传输带宽不足，是制约卫星效能的核心瓶颈。高阶调制解调技术是提升星地传输速率最经济有效的办法。但这就像 一把双刃剑：调制阶数越高，传输速率越快，但信号也越容易受到干扰，导致接收到的数据错误率飙升。如何在高速度下保证数据 的高质量，是业内公认的技术难关。 为解决这一难题，空天院与北京融为科技有限公司联合攻关，成功开发出一套独特的"信号净化"技术。这套技术能有效对抗高速传 输下的信号失真与干扰，如同为数据接收通道清除了路上的"颠簸"和"噪音"，从而构建起一套高性能的地面接收系统，为本次实验 提供了坚实的技术保障。 记者14日从中国科学院空天信息创新研究院（以下简称空天院）获悉，我国在星地高速通信技术领域 ...

Core Viewpoint - Harbin Electric Machinery Company (HEMC) has successfully won the bid for all four sets of pump-turbine units and associated equipment for the Upper Dait Hydropower Station in Cambodia, marking the first entry of Chinese pumped storage equipment into the international market, thereby enhancing China-Cambodia energy cooperation and contributing to the Belt and Road Initiative [1][2]. Group 1 - The Upper Dait Hydropower Station is located in Kampong Province, Cambodia, and plans to install four pump storage units with a single unit capacity of 250 megawatts, developed under a BOT model by China Heavy Machinery Corporation [1]. - The project is a key cooperation initiative identified by the leaders of China and Cambodia, addressing energy shortages in Cambodia through a multi-energy complementary approach led by the National Energy Administration and the Foreign Investment Department of the National Development and Reform Commission [1]. - HEMC has continuously innovated in the pumped storage sector, focusing on high efficiency, stability, and reliability, with the project utilizing advanced design concepts and manufacturing processes that meet international performance standards [1]. Group 2 - The successful bid for the Upper Dait project highlights HEMC's technical strength and brand influence in the pumped storage field, representing a significant achievement in the company's "going out" strategy and active participation in the Belt and Road Initiative [2]. - HEMC aims to enhance its technological innovation capabilities and product quality to provide superior products and services to global customers, contributing to the green and low-carbon development of the world's energy sector [2].

团队还从土地的可持续"供给"和国家的政策"需求"两个维度，重新打造了未来森林恢复的蓝图。 研究指出，全球仍有巨大的造林潜力，有望每年最多吸收50亿吨的二氧化碳。但在综合考虑土地可 持续利用和国家意愿后，这一潜力会降低到每年15亿吨，造林的实际减排潜力远远低于预期。 "各国的植树造林承诺与土地的潜力存在极大的错位：有土地潜力的国家所做出的承诺相对较少， 而承诺较多的国家，尤其是低收入国家，却缺少足够的土地和相关资源来支撑其造林意愿。"覃章才 说，希望他们的研究成果可以为全球气候变化合作，各国森林资源的不对称和南北国家的权责失衡等问 题提供一定科学参考。 据悉，《科学》杂志的编辑认为，该研究考虑了多种要素，提供了更真实的气候效应评估。 为给地球"降温"，全球亟待减少二氧化碳排放并增强生态系统的二氧化碳吸收能力。森林作为天然 的"吸碳器"，是调节气候的"绿色空调"，而植树造林也被认为是极具成本效益的气候解决方案之一。 "然而，当前学界对未来植树造林能吸收多少二氧化碳存在巨大分歧。争议主要缘于两点：一是， 虽然植被固碳能力相对明确，但土壤的碳变化还很难算清；二是，针对全球适合造林的土地面积，不同 研究间的估算值相差巨 ...

Core Points - The Earth is currently experiencing a significant geomagnetic storm, with the real-time geomagnetic activity index reaching a maximum level of 9, indicating intense space weather activity [1] - The geomagnetic storm is a result of recent strong solar activities, including multiple high-intensity solar flares classified as X and M levels, which have caused disturbances in the Earth's magnetic field [1][2] - The ongoing solar activity is expected to allow for aurora observations in northern regions of China, particularly for observers located north of the 40th parallel [2][3] Group 1 - The geomagnetic storm began on November 12, with the potential for auroras to be visible in northern China over the next three days [1] - Solar flares on November 5 reached intensities of X1.8 and X1.1, followed by additional flares of M7.4 and M8.6, contributing to the geomagnetic disturbances [1] - The solar activity is characterized by a large, complex magnetic region on the sun's surface, which has been responsible for multiple medium to high-intensity flares and significant coronal mass ejections [1][2] Group 2 - Auroras are formed when high-energy particles from space collide with atmospheric molecules, resulting in light emissions, with colors depending on the type of gas and altitude [2] - The observation range for auroras expands during periods of intense solar activity, allowing for potential sightings in lower latitude regions, including parts of northern China [2] - Public recommendations include finding areas with minimal light pollution and facing north at night to capture the auroras using cameras or smartphones [2][3] Group 3 - While geomagnetic storms may affect shortwave communication and satellite navigation systems, their impact on human health is negligible [3] - The ongoing solar activity suggests that there may be further opportunities for aurora sightings in various locations around the world, particularly for astronomy enthusiasts [3]

Core Viewpoint - Shandong Province is actively developing marine ranching to enhance its marine fishery industry, contributing to the "blue granary" concept [1] Group 1: Marine Ranching Development - Shandong has established 139 marine ranches at the provincial level and above, including 71 national-level ranches, accounting for 38% of the total in the country [1] - The province has developed a complete industrial chain from aquaculture, fishing, to deep processing [1]