Core Findings - A team from the University of California, Irvine discovered that a combination of Vitamin B3 (niacinamide) and the active component in green tea, EGCG, can rejuvenate aging brain cells and effectively clear harmful protein accumulations associated with Alzheimer's disease [1][2] - The research published in the latest issue of "Aging Science" indicates that this combination significantly enhances the levels of GTP, a key energy molecule in brain cells, and improves the ability to clear β-amyloid proteins, which are characteristic of Alzheimer's disease [1][3] Mechanism of Action - The study utilized a gene-encoded fluorescent sensor named GEVAL to monitor GTP dynamics in neurons of aged Alzheimer's model mice, revealing a continuous decline in GTP levels with age, particularly in mitochondria, which severely impacts autophagy, the process of clearing damaged components [1] - Neurons treated with niacinamide and EGCG showed GTP levels restored to those of younger cells, leading to improved energy metabolism, activation of key proteins responsible for cellular transport, and efficient clearance of β-amyloid aggregates, thereby reducing oxidative stress associated with neurodegeneration [2] Implications for Treatment - The findings suggest that the combination of these two natural dietary supplements may serve as a new tool in combating cognitive decline and Alzheimer's disease [3]

斯格明子最早在磁性材料中被发现，因其稳定性高、尺寸小、动力学特性独特，在自旋电子学和存储器 领域备受关注。此次在超流体中发现新型斯格明子，不仅为相关技术提供了新思路，也有助于拓展对量 子体系的理解。 为验证这一设想，团队将锂原子气体冷却至接近绝对零度，制备出一种多组分玻色—爱因斯坦凝聚态 （量子超流体），并在其中形成两股速度不同的流体。在它们的交界面上，首先出现了波状指形结构， 类似经典湍流；随后，在量子力学与拓扑学规则的作用下，生成了特殊涡旋。 团队发现，这些涡旋是一种此前未知的拓扑缺陷，即偏心分数斯格明子。与常见的对称、居中的斯格明 子不同，EFS呈弯月形，还包含嵌入奇点。这些点打破了原有的自旋结构，造成尖锐畸变。他们表示， 《星空》画作右上角的弯月，看起来就像一个EFS。 梵高的名画《星空》百余年来拨动着无数艺术爱好者的心弦。那旋转涌动的夜空，似乎与物理学中量子 湍流的纹理产生了耐人寻味的共鸣。日本大阪公立大学与韩国科学技术院研究团队首次在量子流体中观 测到"量子开尔文—亥姆霍兹不稳定性"（KHI），并发现了一种形态酷似《星空》中弯月的新型涡旋结 构，即偏心分数斯格明子（EFS）。这一现象早在数十年前便 ...

澳大利亚昆士兰科技大学研究团队开发出一种先进的遥感系统，可精准探测并绘制南极苔藓和地衣的生 长情况，为南极生态研究和全球气候变化监测提供关键支持，相关成果发表于最近的《科学报告》期 刊。 这项成果为南极生态监测提供了新技术，有助理解气候变化对南极生态的影响，推动全球生态保护。 （文章来源：科技日报） 该遥感系统创新性地结合了无人机高光谱相机、GNSS-RTK技术和高分辨率RGB无人机图像。团队用6 种针对极地植物的光谱指数训练模型，结果表明，新模型的性能远超传统指标，在特征重要性评估中表 现卓越。在植被标记环节，团队测试了12种不同的AI模型，其中表现最佳的模型准确率达到约99%，且 在严格测试中保持稳定性能，这为未来的数据处理工作提供了可靠保证。 通过30米和70米高度试飞，团队发现较高的飞行高度适合区域概览，而低高度可捕捉精细细节，能从局 部扩展至整个山谷应用。仅用8个关键波长的轻量版系统即可生成可靠地图，提升了调查效率和成本效 益。 苔藓和地衣堪称南极生态的"绿色压力晴雨表"，在生物地球化学循环、土壤保温及生物多样性维持中起 着关键作用。受气候变暖、极端天气和人类活动影响，这些植被生存面临挑战。 ...

新一期《自然》杂志刊登了一项里程碑式研究：美国斯坦福大学医学院团队利用非基因匹配的健康前体 细胞，替换掉罹患桑德霍夫病小鼠超过半数的病变小胶质细胞，使实验鼠寿命从135天延长至250天，运 动功能与探索行为几乎恢复至正常水平。这也是首次为泰萨克斯病和桑德霍夫病等目前无药可治的致命 性脑病提供了"即用型"细胞疗法蓝图。 该成果同时解决了三大难题：无需全身毒性预处理、无需基因编辑即可补充缺失酶、避免排异反应。方 案所用放射剂量、微胶质清除剂及免疫抑制剂均已用于其他疾病，具备快速进入临床的潜力。同时，该 疗法不依赖患者自身细胞，未来有望像输血一样成为"货架产品"，大幅降低成本与等待时间。 团队指出，阿尔茨海默病、帕金森病等常见神经退行性疾病同样伴随小胶质功能障碍，这或许是溶酶体 病的"慢速版本"。如果后续人体试验成功，受益者远不止罕见病患儿，而是数百万神经退行性疾病患 者。下一步，团队计划在更接近人类的大型动物模型中验证这种疗法的安全性，并与美国食品和药物管 理局讨论设计早期临床试验。 （文章来源：科技日报） 泰萨克斯病和桑德霍夫病同属溶酶体贮积症。患儿因缺乏关键酶，神经"清道夫"小胶质细胞及邻近神经 元内代谢垃圾 ...

Core Viewpoint - NASA is accelerating its lunar nuclear reactor construction plan, aiming to develop a 100-kilowatt fission reactor system for launch by 2030, which is seen as crucial for the Artemis lunar program and a strategic asset in the new space race [1][2]. Group 1: Lunar Nuclear Reactor Development - NASA plans to initiate industry bidding for a 100-kilowatt lunar nuclear fission reactor system, with a target launch by 2030 [1]. - The nuclear reactor is intended to provide a stable energy supply for a lunar base, which is essential for long-term exploration and operations on the Moon and Mars [2][4]. - The reactor's design is expected to utilize uranium fuel and include a multi-layer shielding system to protect astronauts from radiation [4]. Group 2: Challenges and Concerns - Experts express skepticism about the feasibility of deploying a nuclear reactor on the Moon by 2030, citing significant technical and logistical challenges [6]. - Key challenges include ensuring the reactor can operate under extreme lunar conditions, such as temperature fluctuations and low gravity, as well as navigating lengthy approval processes [6]. - The development of materials that can withstand high temperatures and the safe transport of nuclear materials to space are also highlighted as critical hurdles [6]. Group 3: Strategic Implications - The push for a lunar nuclear reactor is partly driven by concerns over the U.S. losing its leadership in space exploration, especially with increasing collaboration between China and Russia on lunar projects [2][3]. - The first country to establish a nuclear reactor on the Moon could potentially claim exclusive rights to certain areas, impacting U.S. interests in lunar exploration [3].

Core Insights - The article discusses the successful implementation of the world's first drug molecular property prediction application based on quantum edge encoding technology by Benyuan Quantum Computing Technology (Hefei) Co., Ltd. in collaboration with the University of Science and Technology of China and the Hefei Comprehensive National Science Center Artificial Intelligence Research Institute [1][2] - This technology significantly enhances the precision of drug discovery by allowing for simultaneous processing of atoms and chemical bonds at the quantum level, akin to equipping drug development with a "quantum microscope" [1][2] Group 1 - The research team has developed a quantum embedded graph neural network architecture that integrates the innovative quantum edge encoding technology and quantum node embedding model [1] - This advancement has led to a substantial increase in the accuracy of predicting key drug properties, with the accuracy for HIV antiviral drug screening rising from 73% to 97%, and Alzheimer's disease drug prediction accuracy increasing from 64% to 70% [2] - The drug toxicity prediction application based on this technology is now available on the Benyuan Quantum Computing Cloud Platform [1]

Core Viewpoint - The "Jiurang Yungxing" agricultural model, developed by Northwest A&F University, represents a significant advancement in modern agriculture by integrating multi-source data and providing precise solutions for various agricultural challenges [1][2]. Group 1: Agricultural Model Development - "Jiurang Yungxing" is the first agricultural model trained and released on a domestic computing platform, addressing issues of data fragmentation and low analysis efficiency in traditional agriculture [1]. - The model incorporates advanced methods such as multi-source data fusion, knowledge graph construction, and intelligent analysis and decision-making, applicable across six major agricultural sectors [1]. Group 2: Practical Applications and Collaborations - The model has been implemented in collaboration with agricultural enterprises managing thousands of acres, applying industrial-level control to the farming process by standardizing over a hundred operational nodes [2]. - "Jiurang Yungxing" has been piloted in regions including Shaanxi, Shanxi, Sichuan, Gansu, Ningxia, Xinjiang, and Inner Mongolia, serving over 200,000 acres and generating economic benefits exceeding 100 million yuan [2]. Group 3: Future Aspirations - The model aims to facilitate human-machine interaction in agriculture, with future agricultural robots expected to understand human commands, making the model a bridge for precise control and execution [2].

Core Insights - The Jianghuai Center showcased the S1 robot, marking a significant breakthrough in the robotics field in Anhui Province [5][10] - The S1 robot features a unique rope-driven mechanism, allowing for more flexible and gentle interactions compared to traditional rigid-arm robots [5][10] Group 1: Product Features - The S1 robot has 46 degrees of freedom and is equipped with various sensors, including laser radar and depth cameras, enabling multi-dimensional scene interaction [5][10] - The rope-driven arm design reduces impact force during operation, making it safer for human interaction [5][10] Group 2: Application Scenarios - The S1 robot is designed for service-oriented environments such as homes, hotels, and retail stores, capable of tasks like meal preparation and cleaning [10] - The technology behind the S1 includes zero-sample visual perception and intelligent control algorithms based on physical world constraints [10]

8月9日，2025年中草药囊泡研究与应用全球学术会议在广东省广州市举行。与会专家学者共同分享药用 植物囊泡的高水平研究成果，促进国内外合作，助力中医药传承创新以及现代化、国际化发展。 本次大会由中草药囊泡广东省工程研究中心、广东省中医药学会、广州中医药大学第三附属医院主办， 广州中医药大学第三附属医院医学检验科承办。 清华大学药学院教授、全球细胞外囊泡网络亚太区联络员尹航指出，细胞外囊泡作为一个细胞间通讯的 平台技术，为中医药产业升级提供了一个前所未有的机会。在全球细胞外囊泡蓬勃发展浪潮之下，我们 需要在法规、政策、原料供应等方面进行更多国际合作，力争让中草药细胞外囊泡为中药产业升级和国 际化开辟了新路径，让古老智慧与现代科技跨界融合。 （文章来源：科技日报） 南方医科大学基础医学院教授、广东省中医药学会中草药囊泡研究与应用专业委员会副主任委员樊俊兵 介绍，水果富含很多活性成分，包括维生素、矿物质、抗氧化剂等。果蔬囊泡在口服稳定性和生物相容 性上更有优势，未来在口服药物递送系统、功能性食品开发等领域应用前景广阔。 广州中医药大学第三附属医院医学检验科主任、中草药囊泡广东省工程研究中心主任、广东省中医药学 会中 ...

Core Viewpoint - The article highlights the significant reforms in Anhui Province's technology system, emphasizing the role of enterprises as the main drivers of technological innovation and project leadership, particularly in the agricultural sector with a focus on high-yield rice varieties [3][5][11] Group 1: Project Development and Funding - Anhui Quanyin High-Tech Seed Industry Co., Ltd. (Quanyin High-Tech) is leading a project on "Research and Application of Ultra-High-Yield Multi-Resistance Hybrid Rice Varieties," which received funding support of 10 million yuan from both Anhui Province and Hefei City, along with an additional 30 million yuan from the company itself [4][5] - The project aims to address the urgent need for high-yield rice varieties and is part of a broader initiative to enhance Anhui's agricultural processing capabilities [4][6] Group 2: Collaborative Innovation - The project involves collaboration with various stakeholders, including industry chain enterprises, universities, and research institutions, creating a comprehensive approach to innovation that spans from material creation to quality control and brand development [4][6] - Over 80% of the major technology projects initiated in Anhui are led by enterprises, ensuring that the outcomes align closely with market needs and facilitating faster industrial application [6][8] Group 3: Role of Enterprises in Innovation - The reform encourages enterprises to become "problem solvers" by allowing them to propose research needs, with over 80% of project demands now coming from businesses [5][10] - Enterprises are also involved in the evaluation of project outcomes, ensuring that innovations meet market demands and have the potential for commercialization [9][10] Group 4: Government Support and Future Directions - The Anhui government is committed to strengthening the role of enterprises in technological innovation, with plans to continue fostering an environment that supports enterprise-led research and development [11] - The province has set ambitious goals for technological advancements in key sectors, including new energy vehicles and artificial intelligence, with significant financial backing to drive these initiatives [8][11]