自民党总裁高市早苗就任带动的股价上涨仍在持续，盘中一度涨幅超过580点，但投资者对市 场过热的担忧也带来了持续的卖压，涨势逐渐放缓…… 10月7日，东京股市的日经平均股指连续第四个交易日上涨，收于4万7950.88点，比前一交 易日上涨6.12点（涨幅0.01%）。这是连续三天刷新历史最高收盘价。股市延续了前一日美 国股市科技股上涨的势头。自民党总裁高市早苗就任带动的股价上涨仍在持续，盘中一度涨 幅超过580点，但投资者对市场过热的担忧也带来了持续的卖压，日经股指涨势逐渐放缓，甚 至出现小幅回落的情况。 Nagomi Capital投资总部部长村松一之表示："'高市交易'至少会持续一周，可以说是蜜月 期"。他认为，自民党新领导班子在10月7日就任后，将维持股市的热情。 日本经济新闻（中文版：日经中文网）田村峻久、佐藤惠里菜 版权声明：日本经济新闻社版权所有，未经授权不得转载或部分复制，违者必究。 日经中文网 https://cn.nikkei.com 视频号推荐内容： 岩井Cosmo证券首席策略师嶋田和昭对目前的股市上涨评价道："即便觉得上涨速度过快，也 不得不跟随市场买入，否则就会错失机会"。这反映出投资者 ...

Core Viewpoint - Japan has produced three Nobel Prize winners in the field of immunology, highlighting its strong research capabilities despite recent declines in global rankings [12]. Group 1: Key Contributions of Japanese Researchers - Shimon Sakaguchi, the latest Nobel laureate, discovered that removing specific immune cells can activate immune responses, leading to autoimmune diseases [3][5]. - The research on regulatory T cells by Sakaguchi has significant implications for cancer treatment, with Rakuten Medical initiating clinical trials for a new cancer therapy targeting these cells [5]. - The emergence of gene manipulation technologies in the 1970s spurred global interest in immunology, with Japanese researchers making notable contributions [7]. Group 2: Historical Context and Influential Figures - Notable figures in Japanese immunology include Shohei Hayashi, who made groundbreaking discoveries in oxygenase and was considered a strong candidate for the Nobel Prize [9]. - Tadao Takahashi and Tadamitsu Kishimoto are other key scholars who have significantly advanced the field, with Kishimoto's work leading to the development of blockbuster drugs like Actemra [10][11]. - The legacy of these researchers has fostered a robust environment for immunology in Japan, with many students and successors continuing their impactful work [9][10]. Group 3: Current Challenges and Future Directions - Despite its historical strengths, Japan's scientific competitiveness is declining, necessitating policies to nurture talent and translate research into innovation [12][13].

Core Viewpoint - The 2025 Nobel Prize in Physiology or Medicine is awarded to Shimon Sakaguchi, Mary E. Brunkow, and Fred Ramsdell for their discovery of regulatory T cells that suppress abnormal immune responses, paving the way for new therapies for autoimmune diseases, allergies, and cancer [2][4]. Group 1 - Shimon Sakaguchi discovered regulatory T cells that can inhibit immune responses against the body’s own cells, preventing autoimmune diseases [2][4]. - The award recognizes the discovery of peripheral immune suppression, which is crucial for understanding immune system regulation [4]. - Sakaguchi's research began after he read a report on thymectomized mice showing autoimmune disease symptoms, leading him to hypothesize the existence of a T cell type that could control immune overactivity [4][5]. Group 2 - Despite skepticism from other researchers, Sakaguchi proved the existence of regulatory T cells in 1985 and identified key genes involved in their function by 1995 [5]. - He founded RegCell, a startup in California, in 2016 to promote the application of his research findings [5]. - The potential applications of manipulating regulatory T cells include treating autoimmune diseases and preventing organ transplant rejection [7]. Group 3 - The Nobel Prize ceremony will take place on December 10 in Stockholm, Sweden, with a total prize amount of 11 million Swedish Krona to be shared among the three laureates [7]. - Sakaguchi has received multiple prestigious awards throughout his career, including the Keio Medical Prize in 2008 and the Robert Koch Prize in 2020 [8].

Core Viewpoint - The 2025 Nobel Prize in Physiology or Medicine will be awarded to Professor Shimon Sakaguchi from Osaka University and two others for their discovery of regulatory T cells that inhibit immune responses, paving the way for new therapies for autoimmune diseases, allergies, and cancer [2][4]. Group 1 - The awarded research focuses on the core mechanisms of the immune system [4]. - The discovery of regulatory T cells acts as a "brake" on immune responses [2]. - This research opens new avenues for developing therapies for various diseases, including autoimmune diseases and cancer [4].

中国女性尽情享受日本一人游 原创 阅读全文 日经GO ...

Core Viewpoint - The article discusses the potential economic policies of Japan's new Prime Minister, Kishi Sanae, who is expected to adopt a fiscal approach similar to Abenomics, emphasizing the need for active fiscal measures to address rising prices and inflation risks [2][4]. Group 1: Economic Policy Stance - Kishi Sanae identifies herself as a successor to Abenomics, advocating for active fiscal policies and monetary easing, while expressing caution regarding the Bank of Japan's interest rate hikes [2][6]. - She has proposed a "responsible active fiscal" approach, suggesting that issuing deficit bonds may be acceptable if necessary, which distinguishes her from other candidates [5][6]. - Kishi's fiscal target is based on "net debt balance," which is calculated by deducting financial assets from the total debt of the national and local governments, with a current ratio of 136% relative to GDP as of 2023 [5][6]. Group 2: Inflation and Economic Conditions - The Japanese government's debt-to-GDP ratio is reported to be as high as 240%, indicating significant room for increased fiscal spending under Kishi's proposed framework [6]. - Kishi has previously advocated for temporarily freezing the goal of achieving a primary balance surplus, prioritizing flexible fiscal spending in response to the economic downturn caused by the COVID-19 pandemic [6]. - The article highlights concerns regarding the potential for rising prices if demand is stimulated without fiscal reform, as Japan faces a new inflationary environment [8]. Group 3: Monetary Policy Perspective - Kishi is viewed as a monetary policy "dove," emphasizing that both fiscal and monetary responsibilities lie with the government, and she has criticized the idea of raising interest rates at this time [7][8]. - She has previously stated that raising interest rates would be detrimental to personal consumption and corporate investment, expressing concerns about a return to long-term deflation [7]. - The rising interest rates in Japan, with the 10-year government bond yield reaching 1.67%, are expected to increase the financial burden on households, particularly in terms of housing loans [8].

Core Viewpoint - The article discusses the personnel adjustments within Japan's ruling Liberal Democratic Party (LDP) under the leadership of new party president Takashi Saito, emphasizing the integration of factions to strengthen governance and maintain party unity [1][3]. Group 1: Personnel Changes - Takashi Saito is coordinating the appointment of Shunichi Suzuki from the Aso faction as the LDP Secretary-General and Taro Aso as Vice President, aiming to solidify the Aso faction as a pillar of the administration [1][3]. - Saito plans to decide on key positions such as Secretary-General, General Affairs Chairman, and Policy Research Council Chairman by October 7, with an expectation to be named the 104th Prime Minister in mid-October [3]. - The inclusion of former competitors in the presidential election for significant roles is also being considered, reflecting a strategy to unify the party [3]. Group 2: Political Strategy - Saito's governance approach emphasizes "active participation of all" and "collective strength of all generations," indicating a desire for inclusivity within the party [3]. - The article highlights the historical context of previous LDP presidents sidelining their election rivals, suggesting Saito's strategy aims to avoid such pitfalls given the current political landscape [5]. - Saito is also considering appointing former Defense Minister Minoru Kihara to a significant position, indicating a focus on maintaining strong alliances within the party [5]. Group 3: Policy Focus - Saito's immediate policy priorities include addressing rising prices, such as the repeal of the temporary gasoline tax rate, and discussing tax and social security reforms for medium to long-term strategies [6]. - The article notes that the Japan Restoration Party is open to negotiations for joining the ruling coalition, while the Komeito party has expressed concerns over certain policy proposals [6]. - Saito is also expected to engage in diplomatic efforts, including coordinating a visit from U.S. President Trump around October 28 [6].

Core Viewpoint - The Japanese stock market experienced a significant surge following the election of new Liberal Democratic Party president, Sanae Takaichi, with expectations of fiscal expansion and monetary easing driving investor sentiment [4]. Group 1: Market Performance - On October 6, the Nikkei average index rose by 2,175.26 points, marking a 4.8% increase and reaching a record high of 47,944.76 points [2]. - This single-day increase is noted as the fourth largest since the index's inception [2]. Group 2: Political Impact - The election of Sanae Takaichi, the first female president of the Liberal Democratic Party, shifted market expectations, leading to a rapid buying of Japanese stocks and selling of yen [4]. - The market had initially anticipated the election of Agriculture Minister Yoshikazu Koizumi, making Takaichi's victory a surprise that fueled optimism among investors [4]. Group 3: Sector Performance - Stocks related to Takaichi's proposed policies on defense, nuclear fusion, and space saw significant buying interest, with companies like Mitsubishi Heavy Industries, IHI, Fujitsu, and Mitsubishi Electric reaching new highs [4]. - Cybersecurity stocks such as NEC and Trend Micro also experienced substantial price increases [4]. Group 4: Market Sentiment - Approximately 90% of stocks in the Tokyo Stock Exchange Prime market saw gains, reflecting a broad-based rally driven by investor optimism regarding potential reforms in Japan [4].

Core Viewpoint - Japan's economy is experiencing a "new normal" characterized by inflation, labor shortages, and rising wages, coinciding with a significant political transition as Shigeru Ishiba steps down and Sanae Takaichi is elected as the new president of the Liberal Democratic Party [1][7]. Group 1: Economic Policy and Market Reactions - The stock market welcomed Takaichi's advocacy for "responsible active fiscal policy," while the bond market expressed concerns over potential increases in government bond issuance [1]. - Despite Ishiba's lack of focus on economic policy, the Nikkei average stock price reached historical highs during his tenure, indicating a paradox in market performance [3]. Group 2: Software Investment Trends - The Bank of Japan's September survey revealed explosive growth in software investment among companies, with large enterprises planning a 10.7% increase in 2025, while medium-sized and small enterprises plan increases of 14.6% and 28.1%, respectively [3][5]. - In contrast, software investment among medium-sized and small enterprises saw declines of 4.8% and 6.4% in 2024, highlighting a significant shift in investment strategy for 2025 to address labor shortages [3]. Group 3: Industry-Specific Insights - The wholesale and retail sectors are projected to increase software investment by 39.5% in 2025, recovering from a 23.9% decrease in 2024, while the accommodation and food services sector is expected to shift from a slight decrease to a 39.5% increase [5]. - The Bank of Japan's report emphasizes that investments should not only address immediate labor shortages but also enhance marginal productivity, aligning with the goal of achieving a nominal GDP of 1,000 trillion yen by 2040 [6]. Group 4: Future Economic Outlook - Despite Japan's declining population, achieving an average nominal investment growth rate of 4.0% could lead to a nominal GDP growth of 3.1% annually, with real GDP growth projected at 1.7% [6]. - The current economic transformation presents an opportunity for the new administration to capitalize on these trends, potentially benefiting businesses and the general public [8].

美国铁 路巨头联合太平洋（Union Pacific）收购同行企业诺福克南方铁路（Norfolk Southern） 7-9月的并购实际交易额同比增长39%，达到1.1031万亿美元。美国经济保持稳健，曾作为不确定性因素 的特朗普关税问题趋于平息，企业正转向积极的经营姿态…… 全球并购市场呈现繁荣态势。英国伦敦证券交易所集团（LSEG）数据显示2025年7-9月的并购实际交易 额同比增长39%，达到1.1031万亿美元，这是7~9月交易额四年来首次突破1万亿美元大关。 除美国经济保持稳健外，曾作为不确定性因素的特朗普关税问题趋于平息，企业正从保守转向积极进攻 的经营姿态。 美国是此次并购热潮的核心驱动力，其交易额同比增长48%，增速超过欧洲的34%和日本的38%。美国 企业作为收购方达成的交易总额达5706亿美元，创下四年来的高点，占全球并购总额的一半。 据金融信息服务机构Mergermarket统计，今年以来，全球范围内交易额超过100亿美元的大型并购案已 达49起，创下历史最高纪录。 日本经济新闻（中文版：日经中文网）纽约 三岛大地 版权声明：日本经济新闻社版权所有，未经授权不得转载或部分复制，违者必究。 ...