Core Insights - The report emphasizes the continuous improvement of the global competitiveness of Chinese innovative pharmaceutical companies, focusing on innovation from both "therapeutic areas" and "technology platforms" [5][6] - The growth of commercial health insurance premiums is expected to provide new payment sources for medical expenses, as the scale of commercial health insurance is projected to reach 977.4 billion yuan by 2024 [29][30] - The report identifies potential therapeutic areas such as metabolic diseases (e.g., weight loss), chronic diseases (e.g., hypertension, hyperlipidemia), and central nervous system diseases (e.g., Alzheimer's, Parkinson's) as key focus areas for innovation [5][38] - Emerging technology platforms like small nucleic acid drugs, radioactive drugs (RDC), and CAR-T therapies are highlighted as significant areas for investment [5][38] Market Review - As of November 15, 2025, the pharmaceutical sector has outperformed the market, with the pharmaceutical index rising by 22.09% compared to a 17.62% increase in the CSI 300 index, resulting in a 4.47 percentage point outperformance [11] - The chemical preparation sector showed the best performance, increasing by 40.52%, followed by medical services (+36.98%) and chemical raw materials (+25.34%) [20] - The overall PE valuation of the pharmaceutical sector is at 30.89 times, which is relatively low compared to historical averages, indicating potential for future growth [22][23] Innovative Drugs - The report notes that the growth of health expenditures in China, which reached 9.06 trillion yuan in 2023, is outpacing GDP growth, indicating a robust market for innovative drugs [26][27] - The analysis of multinational corporations (MNCs) reveals that innovation is a core competitive advantage, with companies like Eli Lilly and Novartis showing significant growth driven by innovative products in advanced technology fields such as GLP-1 and ADC [31][32] - The report highlights the strong sales performance of GLP-1 drugs, with Eli Lilly's Mounjaro generating $6.515 billion in revenue in Q3 2025, reflecting a 109% year-on-year increase [44] CXO and Upstream - The report indicates a slight increase in pharmaceutical financing, with a recovery in business development transactions and H-share IPOs, which is expected to stimulate innovation [5] - The demand for external CXO services is growing, particularly in emerging fields such as peptides and small nucleic acids, while internal CXO orders are also showing signs of recovery [5][39] Medical Devices - The domestic medical device market is currently under pressure due to policy impacts, but improvements are anticipated as companies continue to innovate and expand internationally [5] - The report suggests that the industry fundamentals are expected to improve, with a focus on companies like Mindray Medical and Microelectrophysiology [5][39]

Core Insights - The pharmaceutical industry is experiencing a surge in innovative products, with clear domestic demand and significant potential for international expansion [4][14][25] - Investment opportunities are concentrated in innovative drugs and their supply chains, with a notable performance from CRO/CMO and chemical pharmaceuticals [9][15][17] - The report emphasizes the importance of innovation as the primary solution to industry challenges, driven by stable demand and supportive policies [26][32][41] Industry Overview - The pharmaceutical sector has faced revenue declines, with a 0.9% year-on-year decrease in revenue for the first three quarters of 2025, and net profit down by 2.2% [15][16] - The innovative drug sector has outperformed, with CRO/CMO and chemical pharmaceuticals showing net profit growth of 31.0% and 16.6% respectively [17][18] - The overall market is characterized by low fund holdings and historical valuation bottoms, indicating high investment value [20][25] Demand and Payment Dynamics - The demand for healthcare services is steadily increasing, with a projected 5% growth in total medical visits and hospital admissions in 2024 [26][28] - The aging population is expected to drive long-term demand, with 220 million people aged 65 and above by 2050 [28][30] - The medical insurance fund's income growth has outpaced expenditure growth, leading to a significant increase in fund reserves [32][36] Financing and Market Trends - The IPO market for healthcare has rebounded, with 28 IPOs in the first three quarters of 2025, a 100% increase from the previous year [42][43] - License-out transactions have surged, with transaction numbers increasing by 41% and total amounts reaching $92 billion, indicating a robust market for innovative drug licensing [48][50] - The number of IND applications and new clinical trials for innovative drugs has been steadily increasing, with a notable rise in NDA approvals [53][57] Technological Advancements - The report highlights the emergence of new technologies such as ADC and small nucleic acids, with domestic companies leading in these areas [60] - The focus on dual antibodies and GLP-1 drugs is expected to drive significant growth, with multiple development directions emerging [9][60] - The report notes that domestic companies are increasingly recognized for their innovative capabilities, particularly in the ADC space [60]

成都医学城 转自：新华财经 12月10日，成都药康生命科学研发生产二期项目投产仪式在成都医学城举行。该项目将进一步巩固成都药康在遗传工程领域的核心优势，增强医药创新"源 头"支撑，在更好赋能和加速西部创新药企发展的同时，为成都医学城建强CXO（医药研发生产外包服务组织）赛道提供新助力。 成都药康生物科技有限公 成都药康生物科技有限公司（以下简称"成都药康"）系江苏集萃药康生物科技股份有限公司（以下简称"药康生物"）的全资子公司，2018年8月落地成都温 江，一期项目于2020年11月获批生产许可，业务以"基因编辑模型+药效筛选"为核心，为创新药企提供"源头"服务，提高药物筛选成功率。 成都药康生物科技有限公司 活动现场，成都医学院与成都药康签订战略合作协议，并为双方共建的"衰老机制与干预四川省重点实验室"揭牌。根据协议，成都药康将发挥在模式动物研 发、疾病模型创制及产业化应用领域的领先优势，整合成都医学院在医学教育、科学研究及临床资源方面的优势，共同推动区域生物医药产业高质量发展， 培养高层次应用型人才，加速科研成果转化。 作为成都市发展创新药的主阵地，10余年来，成都医学城深耕生物医药产业，目前已聚集科伦博 ...

Core Viewpoint - The medical services sector experienced a decline of 2.05% on December 2, with Yinosh leading the drop. The Shanghai Composite Index closed at 3897.71, down 0.42%, while the Shenzhen Component Index closed at 13056.7, down 0.68% [1]. Group 1: Market Performance - The medical services sector saw significant individual stock movements, with ST Zhongzhu closing at 2.95, up 3.51%, and Yinosh closing at 41.58, down 7.27% [1][2]. - The total net outflow of main funds in the medical services sector was 9.53 billion yuan, while retail investors saw a net inflow of 6.87 billion yuan [2][3]. Group 2: Individual Stock Analysis - ST Zhongzhu had a trading volume of 1.27 million hands and a transaction amount of 372 million yuan, while Yinosh had a trading volume of 19,500 hands and a transaction amount of 82.48 million yuan [1][2]. - The stock performance varied, with some stocks like Innovation Medical and Dean Diagnostics showing slight declines, while others like ST Zhongzhu showed gains [1][2]. Group 3: Fund Flow Analysis - Main funds showed a net inflow in stocks like Innovation Medical (63.01 million yuan) and Dean Diagnostics (20.61 million yuan), while there were net outflows in several other stocks [3]. - Retail investors contributed to the net inflow in stocks like Innovation Medical and Dean Diagnostics, despite overall sector outflows [3].

中国经济网北京12月1日讯 药康生物(688046.SH)今日收报16.40元，跌幅4.21%。 药康生物首次公开发行股票募集资金总额为11.27亿元，募集资金净额为10.26亿元。药康生物最终 募集资金净额比原计划多2.06亿元。药康生物2022年4月18日披露的招股说明书显示，该公司拟募集资 金8.20亿元，分别用于模式动物小鼠研发繁育一体化基地建设项目、真实世界动物模型研发及转化平台 建设项目。 药康生物首次公开发行股票的发行费用总额为1.00亿元，其中华泰联合证券有限责任公司获得保荐 承销费8278.75万元。 （责任编辑：徐自立） 药康生物于2022年4月25日在上交所科创板上市，发行价格为22.53元/股，公开发行股票数量5000 万股，保荐机构（主承销商）是华泰联合证券有限责任公司，保荐代表人是季李华、洪捷超。目前该股 处于破发状态。 ...

Market Overview - The medical services sector experienced a decline of 2.71% on November 21, with Baihua Pharmaceutical leading the drop [1] - The Shanghai Composite Index closed at 3834.89, down 2.45%, while the Shenzhen Component Index closed at 12538.07, down 3.41% [1] Stock Performance - Notable gainers included Yangguang Nuohua, which rose by 4.47% to a closing price of 61.21, with a trading volume of 86,300 shares and a transaction value of 530 million [1] - Baihua Pharmaceutical saw a significant decline of 9.67%, closing at 9.06, with a trading volume of 292,400 shares and a transaction value of 275 million [2] - Other notable decliners included Chengda Pharmaceutical (-9.58%), Berry Genomics (-8.67%), and Guangzheng Eye Hospital (-7.26%) [2] Capital Flow - The medical services sector experienced a net outflow of 1.325 billion in institutional funds, while retail investors saw a net inflow of 1.332 billion [2] - The table of capital flow indicates that major stocks like Yangguang Nuohua had a net inflow of 10.986 million from institutional investors, while retail investors had a net inflow of 1.374 million [3]

Core Insights - The oncology CRO (Contract Research Organization) services focus on specialized outsourcing for cancer drug development, addressing challenges such as long R&D cycles, high difficulty, and significant risks, thereby efficiently advancing drugs from preclinical stages to market [1][5][4] - The global oncology CRO services market is projected to grow from $7.2 billion in 2020 to $16.2 billion in 2024, with an expected increase to $18.6 billion by 2025 [1][5] - The oncology CRO sector is a highly specialized segment within the broader CRO market, providing comprehensive or partial outsourcing services for clinical trials of anti-cancer drugs [3][4] Industry Definition and Segmentation - CROs provide professional services to pharmaceutical companies and research institutions throughout the drug development process, covering drug discovery, preclinical research, clinical trials, data management, and regulatory submissions [2][4] - Oncology CRO services include preclinical, clinical, and post-marketing services, with preclinical services further divided into hematological cancers, solid tumors, and others [3][4] Current Industry Status - The CRO industry is experiencing significant growth, reflecting a revitalization of the entire pharmaceutical innovation ecosystem [4][5] - The global CRO services market is expected to expand from $62 billion in 2020 to $98.4 billion in 2024, with China's market growing from $7 billion to $10.5 billion in the same period [5] Industry Value Chain - The upstream of the oncology CRO service industry includes basic chemical raw materials, pharmaceutical intermediates, and various scientific instruments [6] - The midstream consists of oncology CRO service providers, which are the core of the industry chain, characterized by technology and talent intensity [6] - The downstream includes demand-side entities such as pharmaceutical and biotechnology companies, medical institutions, and clinical trial researchers [6] Competitive Landscape - The oncology CRO industry in China features a dynamic and layered competitive landscape, with significant differences in scale, service range, client base, and core competencies among companies [9][10] - Key players in the oncology CRO sector include WuXi AppTec, Kanglong Chemical, and others, with a focus on comprehensive services from target validation to new drug registration [10][11] Development Trends - The oncology CRO service industry reflects the pulse of China's pharmaceutical R&D, transitioning from a traditional labor-intensive service sector to a modern, technology-driven, data-intensive industry [13] - The trend towards intelligent systems in clinical CRO services is seen as an inevitable evolution [13]

Core Viewpoint - The domestic R&D demand is showing marginal improvement, driven by the overseas expansion of innovative drugs, leading to a recovery in R&D orders and stabilization of industry prices after a decline in 2023. The CRO sector is expected to see better performance growth by 2026, while the CDMO industry has also reached a bottom and is poised for continued strong growth due to robust demand for new molecules and new orders [1][2][3]. CRO Sector - The domestic R&D demand is recovering, with an increase in orders and stabilization of prices, indicating a clear upward trend for CRO companies. Clinical CROs like Tigermed, Nossan, and Prasis are expected to see revenue growth turning positive by 2025, with significant contributions from overseas business [2][3]. - The recognition of domestic CRO clinical data is improving, which is beneficial for companies like Tigermed [2]. CDMO Sector - The CDMO sector has seen a recovery in performance, with new orders continuing to improve quarterly. The global demand for innovative drug R&D is driving growth in new orders and backlog [3]. - The industry is benefiting from increased capacity utilization and profitability, with a strong certainty of performance and profit growth expected to continue into 2026 [3]. Life Sciences Sector - The life sciences upstream sector is experiencing a dual drive from domestic substitution and overseas expansion, with urgent demand for domestic alternatives in areas like cell culture media and biological reagents. Companies are expected to capture market share through new product categories and cost-effective offerings [4]. - The demand for specific segments such as drug efficacy, antibodies, and proteins is increasing, indicating a clear long-term growth logic for the industry [4]. API Sector - The raw material pharmaceutical industry is currently in a phase of price bottoming and supply surplus, with traditional product performance under pressure. However, companies are extending their business into generics, innovative drugs, and specialty APIs, which may lead to value reconstruction through business structure optimization [5]. - The valuation of raw material pharmaceutical companies is at a low point, presenting opportunities based on changes in new business layouts [5]. Investment Recommendations - For clinical and preclinical CROs, companies like Tigermed, Nossan, and Yinos are recommended due to the gradual recovery of the industry and expected improvement in order structure [6]. - In the CDMO sector, companies such as WuXi AppTec, WuXi Biologics, and others with strong fundamentals and capacity advantages are highlighted for their potential benefits from industry recovery and high demand for new molecules [6]. - In the life sciences upstream sector, companies like Baitai Biotechnology and others are recommended due to accelerated domestic substitution and strong overseas growth [6]. - Companies like Pro Pharma and Huahai Pharmaceutical are noted for their new business layouts that are expected to contribute significant value increments [6].

Core Viewpoint - The company announced a cash dividend of 0.03 yuan per share (including tax) for the first half of 2025, with key dates for shareholders [1] Group 1 - The cash dividend is set at 0.03 yuan per share [1] - The record date for shareholders is November 19, 2025 [1] - The ex-dividend date is November 20, 2025 [1]

2024 年 10 月 29 日，公司召开第二届董事会第八次会议，审议通过了《关 于以集中竞价交易方式回购公司股份方案的议案》，同意公司使用自有资金和股 票回购专项贷款资金通过集中竞价交易方式进行股份回购，回购股份将用于员工 持股计划或股权激励，回购股份的资金总额不低于人民币 2,200 万元（含），不 超过人民币 4,000 万元（含），回购股份的价格不超过人民币 18 元/股（含），回 购股份的期限自董事会审议通过本次回购股份方案之日起 12 个月内。 核查意见 华泰联合证券有限责任公司 关于江苏集萃药康生物科技股份有限公司 差异化分红送转特殊除权除息处理事项的核查意见 华泰联合证券有限责任公司（以下简称"华泰联合证券"或"保荐人"）作 为江苏集萃药康生物科技股份有限公司（以下简称"药康生物"、"公司"或"发 行人"）首次公开发行股票并在科创板上市持续督导阶段的保荐人，根据《中华 人民共和国公司法》《中华人民共和国证券法》及《上海证券交易所上市公司自 律监管指引第 7 号——回购股份》等法律法规的规定，对药康生物 2025 年半年 度利润分配所涉及的差异化权益分派特殊除权除息处理（以下简称"本次差异化 分 ...