Group 1: Policy Support for Pharmaceutical Innovation - Beijing encourages local production of innovative pharmaceuticals, supporting enterprises in importing significant drug and medical device varieties, and promoting the industrialization and large-scale application of innovative products [1] - Shenzhen offers financial incentives for innovative drugs that complete clinical trials and achieve domestic and international market entry, with rewards up to 30 million yuan based on clinical trial phases [2] Group 2: Company Developments - Heng Rui Medicine grants exclusive commercialization rights of its new drug SHR7280 to Germany's Merck, receiving an upfront payment of 15 million euros and potential milestone payments and sales royalties [3] - East China Pharmaceutical's subsidiary receives approval for clinical trials of DR30206, a novel antibody fusion protein targeting PD-L1, VEGF, and TGF-β, marking a significant advancement in its development [4] Group 3: Market Trends and Opportunities - Blood product stocks, including Wei Guang Bio and Pai Lin Bio, experience a surge due to the rigid demand for blood products and potential price increases from U.S. tariffs, benefiting domestic companies and presenting strategic opportunities for market share growth [6]

Core Viewpoint - The recent imposition of a 34% tariff on U.S. imports by China is expected to benefit domestic blood product companies, as it may lead to a price increase for imported human albumin, thereby enhancing the market share of domestic products [3][4]. Group 1: Market Impact - The demand for blood products is relatively inelastic, and the tariff is unlikely to significantly affect overall demand due to its essential nature [4]. - China imports over 60% of its human albumin products, with the U.S. being a major supplier, exporting $54.6 billion in blood products in 2024 [4]. - The price of imported human albumin is expected to rise, reducing its competitive advantage over domestic products, which may lead to an increase in market share for local companies [5]. Group 2: Pricing Dynamics - As of April 6, 2025, domestic human albumin prices are slightly higher than imported ones, but the tariff may eliminate the price advantage of imports [5]. - For example, the price range for imported human albumin (10g specification) is between 345-438 RMB, while domestic products range from 359-580 RMB [5]. Group 3: Supply Chain and Industry Structure - The blood product industry is characterized by a limited number of manufacturers, creating an oligopoly with companies like Tian Tan Bio, Shanghai Raist, and Hualan Biological [6]. - The industry is less affected by geopolitical risks due to its self-sufficient supply chain and the nature of its products [6][7]. - The ongoing trade tensions may enhance the internal circulation advantages of the blood product industry, supporting its long-term growth prospects [7].

Group 1 - The blood products sector is experiencing growth, with companies like Shijiazhuang Yiling Pharmaceutical, Palin Bio, Boya Bio, and Tiantan Bio seeing stock price increases [1] - Shanxi Securities reported strong demand for immunoglobulin and albumin, with a projected market share of 6.5% and 2.5% for the company in 2023, respectively [1] - The domestic market for immunoglobulin is expanding, and the company is expected to benefit from the launch of new generation immunoglobulin products [1] Group 2 - Boya Bio aims to achieve a plasma collection of 630.6 tons in 2024, representing a year-on-year growth of 10.4%, with its main facility collecting 522.04 tons, up 11.7% [1][2] - The company is committed to compliance and operational efficiency, expecting double-digit growth in plasma collection by 2025 [1][2] - The blood products industry has not yet been included in national centralized procurement, but local and regional procurement initiatives have begun since January 2022 [2] Group 3 - Boya Bio is focusing on international expansion through product registration and technical cooperation, aiming to increase market share for immunoglobulin and factor VIII products [2] - The company is advancing innovative treatments for rare diseases, including small nucleic acids and gene therapies, to enhance its global presence [2] - The company’s president emphasized a focus on optimizing plasma utilization and enhancing product structure to improve profitability [3]

Investment Rating - The industry investment rating is "Recommended" [1] Core Insights - The report highlights the impact of escalating trade conflicts on the supply chain of pharmaceuticals, particularly regarding the exemption of certain drugs from tariffs, which reflects the U.S.'s reliance on global pharmaceutical supply chains [3] - The report emphasizes the importance of international markets for Chinese pharmaceutical exports, with a projected export value of $107.96 billion in 2024, indicating a growth of 5.9% year-on-year [4] - The report discusses the potential changes in the supply landscape for blood products due to new tariffs, which may accelerate domestic substitution opportunities [6] - The report notes the ongoing evolution of raw material applications, particularly in the nicotine sector, as companies explore new production avenues [8] - The report indicates that the optimization of centralized procurement policies may alleviate pricing pressures on traditional pharmaceutical companies [10] - The report outlines advancements in CAR-T cell therapies, with significant sales growth and the potential for cost reductions in the future [12] Summary by Sections 1. Pharmaceutical Market Tracking - The pharmaceutical industry outperformed the CSI 300 index by 2.57 percentage points in the past week, ranking third among 31 primary industry indices [23] 2. Pharmaceutical Sector Trends and Valuation - The pharmaceutical sector's index has shown a 3.15% increase over the past month, outperforming the CSI 300 index by 4.20 percentage points [40] - The current PE (TTM) for the pharmaceutical sector is 31.25, which is below the historical average of 32.95 [45] 3. Recent Research Achievements - The report lists various deep-dive studies conducted by the research team, focusing on supply and demand dynamics in the blood products sector and the impact of policy support on inhalation drug markets [49] 4. Important Industry Policies and News - Recent policy updates include the release of the 2025 edition of the Pharmacopoeia of the People's Republic of China, which will take effect on October 1, 2025 [52] - Significant industry news includes the approval of new drug applications by major pharmaceutical companies, indicating ongoing innovation and market activity [54][55]

Investment Rating - The report suggests a positive outlook for the pharmaceutical industry, indicating a potential for outperformance compared to the overall market [27]. Core Insights - The report highlights the impact of the recent U.S. tariff measures, which include a 34% additional tariff on Chinese goods, and the subsequent Chinese countermeasures that may benefit domestic pharmaceutical companies [3][4][5]. - It emphasizes the growth in China's pharmaceutical exports, particularly to the U.S., which reached $19.05 billion in 2024, marking an 11.7% increase year-on-year [6][7]. - The report identifies specific sectors within the pharmaceutical industry that may benefit from the tariff situation, including blood products, high-end raw materials, medical devices, and innovative drugs [18][19]. Summary by Sections Tariff Impact - The U.S. has implemented a 34% tariff on Chinese goods, which affects a wide range of medical supplies and devices, while China has responded with similar tariffs on U.S. imports [4][5]. - The tariffs are expected to disrupt the supply of imported blood products, potentially increasing demand for domestic alternatives [18]. Trade Statistics - In 2024, China's total pharmaceutical trade amounted to $199.376 billion, with exports at $107.964 billion and imports at $91.412 billion, showing a slight decline in imports but a recovery in exports [6][11]. - The U.S. remains the largest market for Chinese pharmaceutical exports, accounting for 17.6% of total exports [7][11]. Sector Opportunities - Blood Products: The tariff on U.S. imports may lead to increased domestic production and sales of blood products, with companies like Tian Tan Biological, Hualan Biological, and others positioned to benefit [18]. - High-End Raw Materials: The report suggests that domestic manufacturers of critical raw materials and consumables may gain market share due to reduced competition from U.S. imports [18]. - Medical Devices: Companies focusing on high-value medical devices are recommended for their potential to capture market share from imported products [18]. - Innovative Drugs: The report encourages investment in companies involved in the development of innovative drugs, particularly those that can replace U.S. imports in oncology and vaccine sectors [19].

华润博雅生物投资者关系活动记录表 证券代码：300294 证券简称：博雅生物 华润博雅生物制药集团股份有限公司投资者关系活动记录表 编号：20250324 | | □特定对象调研 分析师会议 | | | --- | --- | --- | | | □媒体采访 □业绩说明会 | | | 投资者关系活 | □新闻发布会 □路演活动 | | | 动类别 | □现场参观  电话会议 | | | | □其他 | | | 参与单位名称 | 见附件 | | | 及人员姓名 | | | | 2025 时间 | 年 3 月 24 日（星期一）上午 10:00-11:00 | | | 地点 | 不适用 | | | 上市公司接待 | 总裁：梁小明 | | | 人员姓名 | 副总裁、财务总监、董事会秘书：梁化成 | | | | 本次互动交流的情况主要如下： | | | | 一、基本情况介绍 | | | | 公司总裁梁小明先生就 2024 年年度经营情况作基本介绍： | | | | 2024 年，公司聚焦血液制品主责主业，按照"1236"总体 | | | | 经营规划，坚持一个定位、做大两头驱动、做强三个提升，做实 | | | | ...

Group 1: Business Strategy and Focus - The company has determined to focus on the development of blood products and aims to become a world-class enterprise in this field, with plans to dispose of or divest non-blood product businesses as necessary [2][3] - The company is actively applying for new plasma stations in eligible regions to seize opportunities in the "14th Five-Year Plan" for blood product industry development [2][3] Group 2: Operational Goals and Management - The company is enhancing its plasma station operational management and aims for continuous improvement through organizational restructuring and digital empowerment [3] - The management model involves three business centers with vertical penetration of functions to strengthen integration and improve profitability [3][4] Group 3: Product Development and Market Expansion - The company is committed to an internationalization strategy that includes drug international registration and the introduction of innovative products and advanced technologies [3] - New products such as IVIG (10%) and Tetanus Immunoglobulin are expected to be launched in 2025, while C1 Esterase Inhibitor is anticipated to be available by 2027 [4] Group 4: Market Performance - The company’s PCC market share ranks third in the industry, with significant sales achievements in the chronic disease management project for 2024 [4]

证券研究报告 医药生物 | 生物制品 非金融|公司点评报告 hyzqdatemark 2025 年 03 月 24 日 证券分析师 刘闯 SAC：S1350524030002 liuchuang@huayuanstock.com 李强 SAC：S1350524040001 liqiang01@huayuanstock.com 市场表现： | 基本数据 | 21 | | 2025 | 年 | 03 | 月 | 日 | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 收盘价（元） | | | | | | 27.52 | | | | | 一 年 内 高 / 低 | | 最 | | | | 41.98/26.68 | | | 最 | | （元） | | | | | | | | | | | 总市值（百万元） | | | | | | 13,876.93 | | | | | 流通市值（百万元） | | | | | | 13,876.93 | | | | | 总股本（百万股） | | | | | | 504.25 | | | | | 资产 ...

Summary of the Conference Call for Boya Biological Company Overview - **Company**: Boya Biological - **Focus**: Blood products, with a strategic emphasis on expanding production and market presence Key Points and Arguments Financial Performance - **Total Revenue**: 1.735 billion CNY, a year-on-year decrease primarily due to the divestiture of Tianan Pharmaceutical and Fudan Pharmaceutical [3] - **Blood Products Revenue**: 1.514 billion CNY, a year-on-year increase of 4.32%, driven by significant sales growth in prothrombin complex and factor VIII [3] - **Operating Profit**: 397 million CNY, a year-on-year increase of 67.18%, attributed to a lower base from the previous year [3] - **Return on Equity**: Increased by 2.08 percentage points to 5.36% [3] Business Expansion and Acquisitions - **Acquisition**: Successfully acquired 100% of the shares of Roche in Hong Kong, adding a production license and four plasma collection stations, bringing the total to 21 stations across seven provinces [5] - **Plasma Collection**: Achieved 630.6 tons of plasma collection, a year-on-year increase of 10.4%, with the main collection unit growing by 11.7%, surpassing industry averages [5] Product Development and Market Strategy - **Product Sales**: Strong performance in fibrinogen, with PCC and factor VIII exceeding sales targets, and PCC holding the third-largest market share [6] - **International Expansion**: Registered a new immunoglobulin product in Pakistan, indicating a strategic move towards international markets [6] Major Projects - **Smart Factory Project**: Progressing as planned, with the main structure completed and equipment installation ongoing, expected to commence production by the end of 2025, with financial impacts anticipated post-2027 [7][15] Industry Dynamics - **Supply and Demand**: Industry supply pressures have eased, with balanced demand for protein products, although competition for factor products may intensify [10] - **Collective Procurement Strategy**: Actively participating in Guangdong's collective procurement, monitoring policy changes closely [10] Future Projections - **Plasma Collection Goals for 2025**: Expected to exceed 700 tons, with a growth rate of over 10% [3][17] - **New Product Launches**: Anticipated rapid market uptake for new products expected to launch in Q3 2025 [9] Regulatory and Market Considerations - **Regulatory Changes**: Ongoing discussions regarding potential revisions to blood product management regulations, which could significantly impact the industry [20] - **Market Strategy Adjustments**: Focus on regional market penetration, particularly in East China, to optimize existing production capacity [21] Integration and Collaboration - **Sales Team Integration**: Ongoing integration of sales teams from Roche and Boya, aiming for enhanced market coverage and synergy [19] - **Technical Collaborations**: Engaging in technical cooperation with Central Asian countries to expand market reach and capabilities [17] Investment and Future Outlook - **Investment Plans**: Continued focus on core business and strategic acquisitions to enhance market position and operational efficiency [24] - **Long-term Growth Strategy**: Emphasis on technological innovation and market competitiveness to ensure sustainable growth [26] Additional Important Insights - **Market Potential in New Regions**: Significant growth potential identified in Anhui and Inner Mongolia, with strategic plans to address local concerns and enhance operational trust [22] - **Impact of Economic Conditions**: Despite macroeconomic pressures, the company has maintained a strong performance trajectory [11]

Investment Rating - The report maintains a "Buy" rating for the company [5]. Core Insights - The company achieved a revenue of 1.735 billion yuan in 2024, a decrease of 34.58% year-on-year, while the net profit attributable to shareholders was 397 million yuan, an increase of 67.18% year-on-year [1]. - The blood products business generated a revenue of 1.514 billion yuan, accounting for 87.29% of total revenue, with a year-on-year increase of 4.32% [1]. - The company has 20 plasma collection stations and one under construction, with a total plasma collection volume of 630.6 tons in 2024, representing a year-on-year growth of 10.4% [1]. - Several research projects are progressing well, with expectations for new product approvals in 2025 and 2027, enhancing the product pipeline and core competitiveness in the blood products sector [2]. - The company is solidifying its market position in China, particularly in the fibrinogen market, and has achieved significant sales targets in various product categories [2]. Financial Summary - The projected net profits for 2025, 2026, and 2027 are 547 million yuan, 606 million yuan, and 675 million yuan, respectively, with year-on-year growth rates of 37.81%, 10.80%, and 11.33% [3]. - The earnings per share (EPS) are estimated to be 1.08 yuan, 1.20 yuan, and 1.34 yuan for 2025, 2026, and 2027, respectively, with corresponding price-to-earnings (P/E) ratios of 26, 23, and 21 [3][4]. - The company’s revenue is expected to recover to 1.958 billion yuan in 2025, with a growth rate of 12.87% [4]. Market Position and Brand Development - The company has successfully enhanced its brand influence and market coverage through academic conferences and marketing strategies [2]. - The company continues to lead in the fibrinogen market and has achieved a third-place market share in the PCC category [2].