| 证券代码：300482 | 证券简称：万孚生物 | 公告编号：2025-044 | | --- | --- | --- | | 债券代码：123064 | 债券简称：万孚转债 | | 广州万孚生物技术股份有限公司 关于职工代表监事辞职暨补选职工代表监事的公告 本公司及监事会全体成员保证信息披露内容的真实、准确和完整，没有虚 假记载、误导性陈述或重大遗漏。 一、公司职工代表监事辞职的情况 广州万孚生物技术股份有限公司（以下简称"公司"）监事会于近日收到公 司职工代表监事宋庆梅女士的书面辞职报告。宋庆梅女士因个人原因申请辞去公 司第五届监事会职工代表监事职务，辞职后宋庆梅女士不在公司担任其他职务， 公司及公司监事会对宋庆梅女士任职期间为公司的发展做出的贡献表示衷心感 谢！宋庆梅女士原定任期至第五届监事会届满日（2027 年 6 月 13 日）。截至本 公告披露日，宋庆梅女士未持有公司股份，不存在应该履行而未履行的承诺事项。 二、补选公司职工代表监事的情况 鉴于宋庆梅女士的辞职将导致公司监事会成员人数低于法定最低人数，且监 事会职工代表监事人数少于监事会成员的三分之一，为保证公司监事会的正常运 行，根据《公司法 ...

| 证券代码：300482 | 证券简称：万孚生物 | 公告编号：2025-045 | | --- | --- | --- | | 债券代码：123064 | 债券简称：万孚转债 | | 广州万孚生物技术股份有限公司 关于取得产品注册证的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 广州万孚生物技术股份有限公司（以下简称"万孚生物"或"公司"）近日 收到国家药品监督管理局颁发的医疗器械注册证，具体信息如下： | 名称 | 注册证号 | 有效期至 | 预期用途 | | --- | --- | --- | --- | | | | | 该产品基于磁珠法核酸提取和聚合酶链式反应 (PCR)技术原理，与配套的检测试剂共同使用，在 | | 全自动核酸扩增分析 | 国械注准 | 临 2030/08/13 | 床 上 用 于 对 来 源 于 人 体 样 本 中 的 靶 核 酸 | | 仪 | 20253221553 | | | | | | | （DNA/RNA）进行定性检测，包括病原体和人类 | | | | | 基因项目。 | 公司自主研发的全自动核酸扩增分析仪依托经 ...

Core Viewpoint - The company reported a revenue of 1.246 billion yuan and a net profit of 189 million yuan for the first half of the year, facing challenges from intensified competition and demand pressure in the in vitro diagnostic (IVD) industry [1] Business Segments Summary Infectious Disease Testing - The company is enhancing the coverage of influenza testing products in leading medical terminals and is launching new respiratory disease detection products, with a respiratory triad test expected to receive certification by the second half of 2025 [1] - In the U.S. market, the company is rapidly diversifying sales channels for new respiratory detection products [2] Chronic Disease Management Testing - The company is adjusting strategies to strengthen its hospital base, with breakthroughs in chemical luminescence business through projects related to thrombosis, cytokines, and hypertension [2] - The Ucare-6000 fully automated blood gas and biochemical analyzer was launched domestically, providing a cost-effective solution for ICU and respiratory departments in hospitals [2] Toxicology Testing - The company achieved revenue of 145 million yuan in the toxicology sector, a 4.26% increase year-on-year, and is deepening its integrated layout in the North American toxicology market [2] Maternal and Child Health Testing - The company is focusing on strengthening its core competitiveness in the early pregnancy market, with its brands "Xiu'er" and "Jin Xiu'er" receiving multiple recommendations and awards from maternal and infant platforms [2] Research and Development - The company invested 206 million yuan in R&D, launching 95 new products, and holds a total of 681 product registration certificates, ranking among the top in the IVD industry [2] Chemical Luminescence Platform - The company launched the LA-6000 laboratory intelligent assembly line based on the FC-9000 high-speed machine and has over 150 medical device product registration certificates for its single-use chemical luminescence product line globally [3] Immunofluorescence and Pathology - The company introduced two dry fluorescence immunoassay analyzers and received a Class III registration certificate for its human microsatellite instability testing kit, marking a significant breakthrough in tumor precision detection [3] - The AI-assisted diagnostic software for cervical cytology developed by a company it invested in has also been approved, enhancing diagnostic efficiency and accuracy [3] AI Platform Development - The company created the "Wanfuzhijian" intelligent testing AI platform, collaborating with Tencent Health to develop a more intelligent and precise IVD and health service system [4] Global Expansion - The company has established a global service network covering over 150 countries and regions, with local production bases in several countries, including Russia and the Philippines [4] Future Outlook - The company aims to leverage its core technology platforms in immunology, molecular biology, and electrochemistry, focusing on seven major disease categories to become a globally trusted IVD enterprise [5]

Group 1: Macroeconomic Insights - In July, the growth rate of broad fiscal expenditure slowed to 12.1% from 17.6% in June, with an estimated year-on-year growth of 7.6% after excluding special bonds, which is still higher than the nominal GDP growth of 3.9% in Q2, indicating that fiscal easing supports nominal growth [2] - The broad fiscal deficit recorded 352.5 billion yuan, an increase of approximately 213.4 billion yuan year-on-year, highlighting the continued liquidity injection into the real economy through special bonds and capital injections [2] Group 2: Market Activity and Investment Trends - A-share market activity has rebounded, with trading volumes increasing and the number of active retail investors reaching a year-to-date high, indicating sustained interest from retail investors [3] - Private equity product registrations were high, with 666 new products registered in early August, a 6% increase from July, suggesting robust private investment activity [3] - Foreign and insurance capital are expected to be significant sources of incremental investment, with insurance capital's market entry ratio increasing in Q2 2025 [3] Group 3: Industry Developments - The State Administration of Radio and Television's new measures aim to enhance the supply of quality content for television, which is expected to boost viewership and commercial levels in the film and television industry [8] - The strategic importance of rare earths is highlighted, with expectations of price increases due to supply-demand imbalances in 2025-2026, driven by geopolitical factors and domestic policies [9] - The automation of warehousing through robotics is anticipated to transform the logistics industry, with a focus on enhancing efficiency and reducing costs [10] Group 4: Company-Specific Insights - China Everbright Bank has been rated as "Accumulate" with a target price of 4.62 HKD, benefiting from group resources and a strong non-interest income base [12] - Crystal International, a leading garment manufacturer, has been rated "Buy" with a target price of 7.38 HKD, supported by its global presence and strategic acquisitions [13] - Dingdong Maicai, a fresh e-commerce leader, has been rated "Accumulate" with a target price of 2.77 USD, focusing on product strength and market expansion [13] Group 5: Financial Performance Highlights - The financial performance of various companies shows promising growth, with notable increases in revenue and net profit across sectors such as energy, pharmaceuticals, and technology [18][20][22] - For instance, Longyuan Power reported a revenue of 156.57 billion yuan in H1 2025, with a net profit of 33.75 billion yuan, exceeding expectations due to favorable wind power pricing [21] - The performance of companies like Huazhong Medicine and Meihua Biological indicates stable growth and potential for future profitability, supported by innovative product pipelines and market demand [24][33]

Group 1 - The core point of the article highlights that Wanfu Biological (300482.SZ) experienced a significant drop in stock price, opening lower and reaching a decline of 7.46%, with a current price of 22.95 yuan and a total market capitalization of 11.05 billion yuan [1] - For the first half of 2025, the company reported total operating revenue of 1.246 billion yuan, representing a year-on-year decrease of 20.92% [1] - The net profit attributable to the parent company for the same period was 189 million yuan, down 46.82% year-on-year, while the net profit after deducting non-recurring gains and losses was 154 million yuan, a decline of 52.73% [1] Group 2 - The net cash flow from operating activities was -56.31 million yuan, compared to 200 million yuan in the same period last year, indicating a significant deterioration in cash flow [1]

Financial Performance - The company reported a revenue of 1.246 billion yuan for the first half of 2025, representing a year-on-year decline of 20.92% [1] - The net profit attributable to shareholders was 189 million yuan, down 46.82% year-on-year [1] - The net cash flow from operating activities was -56.31 million yuan, indicating a shift from positive to negative [1] - As of the end of June, cash and cash equivalents amounted to 344 million yuan, a decrease of 58.5% from the beginning of the year [1] Product Segmentation - Revenue from infectious disease testing was 379 million yuan, accounting for 30.4% of total revenue, down 21.14% year-on-year due to a decline in domestic respiratory testing demand [2] - Revenue from chronic disease management testing was 563 million yuan, representing 45.2% of total revenue, down 26.06% year-on-year, primarily due to the implementation of centralized procurement in 28 provinces affecting terminal testing prices and sales [2] - Revenue from drug testing was 145 million yuan, making up 11.7% of total revenue, with a growth of 4.26% attributed to increased sales through North American e-commerce channels [2] - Revenue from prenatal and postnatal testing was 138 million yuan, accounting for 11.1% of total revenue, down 11.67% due to a decline in birth rates [2] Profitability and Costs - The gross margin for infectious disease testing was 59.73%, a slight decrease of 0.02 percentage points year-on-year [2] - The gross margin for chronic disease management testing was 72.86%, down 2.00 percentage points [2] - The gross margin for drug testing was 55.76%, an increase of 0.11 percentage points [2] - The gross margin for prenatal and postnatal testing was 43.95%, up 0.67 percentage points [2] Expenses and Investments - Financial expenses surged by 387.74% to 16.69 million yuan, mainly due to exchange losses from fluctuations in the RMB against the USD and EUR, along with reduced interest income [2] - Research and development investment totaled 206 million yuan, representing 16.5% of revenue, with a focus on chemiluminescence, molecular diagnostics, and AI-assisted diagnostics [2]

Core Viewpoint - Guangzhou Wanfeng Biotechnology Co., Ltd. reported its 2025 semi-annual results, showing a revenue of 1.246 billion yuan and a net profit of 189 million yuan, impacted by intensified competition and demand pressure in the in vitro diagnostic industry [1] Group 1: Financial Performance - The company achieved operating revenue of 1.246 billion yuan and a net profit attributable to shareholders of 189 million yuan in the first half of the year [1] - Revenue from toxicology testing reached 145 million yuan, representing a year-on-year growth of 4.26% [1] Group 2: Product Development and Market Strategy - In the infectious disease testing sector, the company enhanced the coverage of influenza testing products in leading medical terminals and introduced new respiratory detection products [1] - The company is expected to obtain certification for its respiratory triple detection product in the second half of 2025 [1] - In chronic disease management, the company adjusted its strategy to strengthen its hospital base, with significant growth in its chemiluminescence business through specialized projects [1] - The Ucare-6000 fully automated blood gas and biochemical analyzer was launched domestically, providing a cost-effective solution for ICU and respiratory departments [1] Group 3: International Expansion and AI Integration - The company has established a global service network covering over 150 countries and regions, with local production bases in multiple countries [2] - A strategic cooperation agreement was signed with Tencent Health to develop an AI platform for intelligent diagnostics and health management [2] - The company aims to focus on seven major disease categories, leveraging its core technology platforms in immunology, molecular diagnostics, and electrochemistry for future growth [2]

Investment Rating - The report maintains a "Buy" rating for the company [7] Core Views - The company achieved revenue of 1.246 billion RMB in 1H25, a year-on-year decrease of 20.9%, and a net profit attributable to the parent company of 189 million RMB, down 46.8% year-on-year, primarily due to domestic policy changes affecting hospital demand and a weaker outbreak of respiratory infectious diseases compared to the same period in 2024 [1][3] - Despite short-term challenges, the company is expected to maintain long-term growth potential due to its expanding product portfolio and improving domestic and international sales networks [1][3] Summary by Sections Revenue and Profitability - The company's gross margin in 1H25 was 62.9%, a decrease of 1.5 percentage points year-on-year, attributed to domestic policy changes impacting product pricing [2] - The sales, management, and R&D expense ratios for 1H25 were 25.6%, 7.3%, and 14.0%, respectively, with increases of 5.4, 0.5, and 1.5 percentage points year-on-year, indicating ongoing investment in commercialization and R&D [2] Business Segments - The U.S. subsidiary's revenue in 1H25 is estimated to have grown nearly 20%, supported by stable toxicology testing and new respiratory testing products [3] - The international department's revenue is expected to show steady growth due to ongoing localization efforts and the introduction of new products [3] - Domestic business revenue is projected to decline in 1H25 due to external environmental factors, but long-term growth is anticipated through strategic advancements in immunofluorescence and other key areas [3] Long-term Business Outlook - Infectious disease testing revenue was 379 million RMB, down 21.1% year-on-year, primarily due to lower outbreak intensity [4] - Chronic disease testing revenue was 563 million RMB, down 26.1% year-on-year, affected by policy changes [4] - Toxicology and prenatal testing revenues were 145 million RMB and 138 million RMB, showing growth of 4.3% and a decline of 11.7% respectively, with expectations for improvement through new product launches and e-commerce channel development [4] Profit Forecast and Valuation - The report adjusts the profit forecast for 2025-2027, estimating net profits of 426 million RMB, 491 million RMB, and 582 million RMB, reflecting downward adjustments of 35% for 2025 and 2026, and 33% for 2027 [5][13] - The company is valued at a 34x PE for 2025, with a target price of 30.09 RMB, up from a previous estimate of 27.07 RMB [5][8]

Core Insights - Wanfu Bio reported a revenue of 1.246 billion yuan and a net profit of 189 million yuan for the first half of the year, facing challenges from intensified competition and demand pressure in the in vitro diagnostics (IVD) industry [1] - The company is committed to advancing its IPD transformation to strengthen core competitiveness, focusing on product innovation and consolidating its advantages in the immunology field [1][5] - Wanfu Bio aims to enhance its global presence through domestic and international dual circulation and digital transformation to maximize internal potential and drive business growth [1] Infectious Disease Testing - The company is enhancing the coverage of its influenza testing products in leading medical terminals and is introducing new respiratory testing products, with a three-in-one respiratory test product expected to receive certification by the second half of 2025 [1] - In the U.S. market, Wanfu Bio is rapidly diversifying sales channels for new respiratory testing products, while also achieving breakthroughs in sales of pre-surgical blood screening products in developing countries [1] Chronic Disease Management Testing - The company is implementing strategic adjustments to solidify its hospital base, with its chemiluminescence business making progress in projects related to thrombosis, cytokines, and hypertension [2] - The Ucare-6000, an automated blood gas and biochemical analyzer, has been launched domestically, providing a cost-effective solution for ICU and respiratory departments in hospitals [2] Toxicology Testing - Wanfu Bio achieved revenue of 145 million yuan in the toxicology testing sector, a 4.26% increase year-on-year, and is deepening its integrated layout in the North American toxicology market [2] Maternal and Child Health Testing - The company is strengthening its core competitiveness in the early pregnancy market, with its "Xiu'er" and "Jin Xiu'er" brands receiving multiple recommendations and awards from maternal and infant platforms [2] Research and Development - Wanfu Bio continues to invest heavily in R&D, with an expenditure of 206 million yuan in the first half of the year, resulting in the launch of 95 new products [2] - The company holds 681 product registration certificates, ranking among the top in the IVD industry [2] Chemical Luminescence and Immunofluorescence Platforms - The company launched the LA-6000 laboratory intelligent assembly line based on its FC-9000 high-speed chemiluminescence machine, and has registered over 150 medical device product certificates for its single-use chemiluminescence products globally [3] - New dry fluorescence immunoassay analyzers FS-1000 and FS-2000 have been introduced, along with a rapid screening reagent for the chikungunya virus [3] Pathology Business - Wanfu Bio developed a human microsatellite instability (MSI) testing kit, becoming the first in China to receive approval for this methodology, marking a significant breakthrough in tumor precision detection [3] - The company’s investment in a digital pathology image-assisted diagnosis software for cervical cells has received approval, representing a milestone in the integration of digital pathology and AI-assisted diagnosis [3] AI Platform and Global Expansion - The company has created an intelligent testing AI platform, "Wanfu Smart Testing," which has been applied in various medical scenarios [4] - Wanfu Bio has established a global service network covering over 150 countries and regions, with local production bases in several countries to enhance its international operations [4] Future Outlook - The company plans to focus on three core technology platforms: immunology, molecular, and electrochemistry, targeting seven major disease categories while advancing its strategies of combination, internationalization, and digitalization [5]

Core Insights - Wanfu Biological (300482.SZ) released its semi-annual report for 2025, indicating a total of 9 institutional investors holding shares, amounting to 86.39 million shares, which represents 17.95% of the total share capital [1][2] - The proportion of shares held by institutional investors increased by 1.10 percentage points compared to the previous quarter [1] - One public fund, Donghai Social Security, increased its holdings, while another, Huabao CSI Medical ETF, saw a slight decrease in holdings [1] Institutional Holdings - The institutional investors include notable entities such as Guangzhou Huiyin Tianyue Equity Investment Fund Management Co., Bank of China - Huabao CSI Medical ETF, and Hong Kong Central Clearing Limited [1] - The total institutional holding percentage stands at 17.95%, reflecting a growing interest from institutional investors [1] Public Fund Activity - One new public fund disclosed its holdings, which is the Southern CSI 1000 ETF, while two public funds, Haifutong Xinrui Mixed A and Haifutong Xinying 6-Month Holding Period Mixed A, were not disclosed in the current period [1] - The overall activity among public funds indicates a mixed sentiment, with one fund increasing and another decreasing its holdings [1] Social Security Fund and Foreign Investment - The National Social Security Fund 118 Combination is the only new social security fund disclosed as holding shares in Wanfu Biological [2] - One foreign institution, Hong Kong Central Clearing Limited, has also newly disclosed its holdings in the company [2]