Core Points - The 2025 National Medical Insurance Negotiation (referred to as "Guo Tan") commenced on October 30, 2023, in Beijing, with negotiations expected to last 4-5 days [2][3] - This marks the 8th adjustment of the medical insurance catalog since the establishment of the National Medical Insurance Bureau, involving five stages: preparation, application, expert review, negotiation, and announcement of results [3] - A total of 644 drugs passed the formal review for the 2025 catalog, with 534 approved for the basic medical insurance catalog and 121 for the commercial insurance innovative drug catalog [3] Group 1 - The first day of negotiations focused primarily on common drugs, including those for infections, anesthesia, and diabetes, while innovative drugs are scheduled for discussion on the second and third days [3] - Some representatives expressed that the price reductions proposed by the National Medical Insurance Bureau were significantly lower than expected, with estimates being 40%-50% below the most pessimistic forecasts [3][5] - The pace of negotiations appeared to be faster than in previous years, with representatives exiting the venue every few minutes, contrasting with the lengthy discussions seen in past negotiations [5] Group 2 - The introduction of the commercial insurance innovative drug catalog is a significant change this year, aimed at integrating basic medical insurance and commercial insurance to better meet diverse medication needs [8][9] - Negotiations for the commercial insurance innovative drug catalog are expected to take place on November 1 and 2, 2023 [9] - A total of 79 drugs applied for both the basic medical insurance and commercial insurance innovative drug catalogs, with a priority given to those that successfully pass the basic medical insurance negotiations first [9][10] Group 3 - The commercial insurance innovative drug catalog will allow for greater participation from commercial insurance companies in the decision-making process regarding drug inclusion and pricing negotiations [9] - Five high-cost CAR-T products are confirmed to be included in the final negotiation list for the commercial insurance innovative drug catalog [10] - Future payment models for innovative drugs may involve initially placing them in the commercial insurance catalog before transitioning to the basic medical insurance catalog after gathering real-world data [10]

Summary of Key Points from the Conference Call Industry and Company Focus - The conference call discusses the strategic sectors in China, particularly focusing on innovative growth companies that are expected to emerge as "China Next Winners" in the context of the country's five-year plans [1][3][4]. Core Insights and Arguments 1. **Five-Year Plans as Investment Roadmaps**: China's five-year plans have historically served as effective roadmaps for investors, highlighting key sectors that are prioritized for growth. Significant alpha generation is often observed in the initial years following the prioritization of these sectors [3][12][13]. 2. **Key Growth Areas Identified**: - **Technology and Innovation**: Growth in semiconductors and artificial intelligence (AI) is anticipated, with a focus on self-reliance and high-tech innovation [3][4]. - **Advanced Manufacturing and Automation**: Chinese companies are expanding in mature automation areas, with new entrants in humanoid robotics benefiting from a large customer base and lower development costs [3]. - **Green Technology Leadership**: China has achieved 50% penetration of electric vehicles, with expectations for full electrification by the end of the decade. Rapid development in solar, wind, and nuclear energy is also anticipated [3]. - **Healthcare and Drug Development**: The aging population is expected to create greater opportunities in healthcare, with the industry catching up to global standards in R&D capabilities [3]. - **Domestic Consumption Boost**: A shift in consumer behavior from material ownership to experiential wealth is noted, benefiting companies focused on experiences rather than goods [3]. - **Urban Air Mobility**: China aims to dominate the low altitude economy, with proactive regulations and infrastructure development supporting this market [3]. 3. **Investment Implications**: The report emphasizes that growth stocks and innovative companies have historically provided the best returns for long-term investors, with a focus on high-growth and highly innovative firms [4][12]. 4. **Top Stock Recommendations**: Key stocks highlighted include Tencent, CATL, Alibaba, Trip.com, Luxshare, Hengrui, and Innovent as potential investment opportunities [4]. Additional Important Insights 1. **Historical Performance of Strategic Industries**: Industries identified as strategic in five-year plans have historically shown an average alpha of 30-40% in the first two years post-inclusion, although returns tend to decline after five years [13][17]. 2. **Characteristics of Historical Winners**: Successful companies typically emerged from mid-cap stocks (around $5 billion adjusted for today's market size), with reasonable valuations (13x PE), operating margins of 6-9%, and long-term earnings growth expectations exceeding 12% [12][50]. 3. **Long-Term Trends**: The report indicates that high-growth and innovative companies have generated significant annualized alpha, with the top 20% of the market leading in innovation yielding 8.5% p.a. alpha over the last decade [12][50]. 4. **Geopolitical and Macroeconomic Influences**: The evolving geopolitical landscape and domestic structural challenges are shaping China's economic and policy environment, emphasizing self-reliance and technological innovation [14][29]. This summary encapsulates the key points discussed in the conference call, focusing on the strategic sectors and companies poised for growth in China, as well as the historical context and investment implications derived from the five-year plans.

Group 1 - The current high-level financial opening and high-quality development of the real economy have become a key theme, with Beijing and Hong Kong being core forces in promoting enterprises going global and capital connectivity [1] - At the 2025 Financial Street Forum, it was highlighted that Beijing enterprises hold significant positions in terms of market value and quantity in the Hong Kong stock market, with an increasing number of tech companies preparing to list in Hong Kong [1][2] - The collaboration between the Beijing Stock Exchange (BSE) and the Hong Kong Stock Exchange (HKEX) aims to support qualified listed companies in applying for listings in each other's markets, enhancing market cooperation and promoting mutual prosperity [2][3] Group 2 - The HKEX has seen a significant increase in IPO activities, with new listings raising HKD 180 billion in the first three quarters of 2023, a twofold year-on-year increase, and subsequent stock placements raising HKD 260 billion, up 270% [4] - The "A+H" listing trend is gaining momentum, with several A-share companies already listed in Hong Kong, and more companies in the pipeline for IPOs [5][6] - The demand for A-share leading enterprises to list in Hong Kong is expected to continue, driven by the need to enhance international influence and attract global capital [6][7] Group 3 - The China Securities Regulatory Commission (CSRC) has issued measures to support leading domestic enterprises in listing in Hong Kong, facilitating a smooth financing channel for overseas listings [7]

Core Insights - The Chinese innovative pharmaceutical industry is rapidly integrating into the global pharmaceutical innovation system, transitioning from a focus on generic drugs to a significant presence in global innovative drug business development (BD) transactions [1][2] - The proportion of China's projects in global innovative drug BD transactions increased from 3% in 2019 to 13% in 2024, with transaction amounts rising from 1% to 28% [2] - By October 2025, the total value of China's innovative drug BD transactions exceeded $100 billion, indicating strong global market recognition of Chinese innovative drugs [2][3] Industry Upgrade Drivers - The shift from generic to innovative drug development, coupled with the aging population's demand, is driving the industry's upgrade [3] - China possesses a competitive talent pool and engineering advantages, creating unique internal competitiveness that is hard to replicate [3] - Significant investment from enterprises and patient capital, along with improved market, innovation ecosystem, and policy environments, is fostering high-quality development opportunities in biopharmaceutical innovation and investment [3] "Going Global" Trend - The trend of Chinese innovative drugs "going global" is positive, with companies leveraging their R&D capabilities to explore international markets [4] - Silver诺医药's innovative drug,依苏帕格鲁肽α, received approval for commercialization in China and Macau, marking a significant milestone for the company [4][5] - 恒瑞医药 is pursuing a dual strategy of "borrowing ships to go out" and "building ships to go out," establishing partnerships with multinational pharmaceutical companies to promote innovative drugs internationally [5][6] Case Studies of Innovation - 华领医药's多格列艾汀 is the world's first glucose kinase activator (GKA) approved for market, showcasing the company's breakthrough in original drug development [6] - The successful transformation of the glucose kinase activator into a marketable drug highlights the innovative approach of华领医药 in recognizing the dual regulatory role of the target [6]

Core Insights - The transformation of earnings presentations from traditional formats to professional platforms focusing on deep communication is highlighted, enhancing the connection between companies and investors [1][4][9] Group 1: Participation and Engagement - Over 90% of listed companies have maintained a stable annual report earnings presentation rate for three consecutive years, with a participation rate of 99% among key executives [1][3] - The number of earnings presentations has increased significantly, with 1,768 sessions held in the Shanghai Stock Exchange Roadshow Center, covering 85.36% of listed companies [1][2] - The engagement quality has improved, with over 80% of companies responding actively during presentations, and the use of "video + text" formats increasing by 6% [2][3] Group 2: Format and Innovation - Earnings presentations have evolved from a single format to a diverse range of communication styles, with over 99% of companies conducting online presentations [5][6] - The introduction of short video formats and interactive elements has made presentations more engaging, with a notable increase in collective earnings meetings focusing on industry and regional factors [2][5] - Companies are utilizing multiple platforms for live streaming and playback, enhancing information dissemination and accessibility for investors [5][6] Group 3: Strategic Communication - High executive attendance has become the norm, with over 400 companies holding separate earnings presentations while also participating in collective events, enhancing communication depth and sincerity [3][7] - Companies are increasingly recognizing the importance of earnings presentations as a platform for direct communication with investors, breaking down communication barriers [3][4] - The involvement of external experts and analysts in presentations has provided investors with independent insights, enriching the understanding of long-term investment value [7][8]

Core Insights - The financial high-level opening and high-quality development of the real economy have become key themes, with Beijing and Hong Kong as core forces in promoting enterprises going global and capital connectivity [1] - The Hong Kong Securities and Futures Commission Chairman highlighted the significant market value and number of Beijing enterprises listed in Hong Kong, while the Hong Kong Stock Exchange Chairman noted an increasing number of tech companies preparing to list in Hong Kong [1][6] Group 1: Market Opportunities - There are over 200 companies from Beijing listed on the Hong Kong stock market, including major firms like Sany Heavy Industry and China Aluminum [4] - The "A+H" dual listing model is gaining traction, with 46 companies including Agricultural Bank of China and China Shenhua Energy listed in both markets [4] - The collaboration between the Beijing Stock Exchange and Hong Kong Stock Exchange aims to facilitate cross-border listings, enhancing market cooperation and promoting mutual prosperity [3][5] Group 2: Financial Performance - In the first three quarters of 2023, new listings in Hong Kong raised HKD 180 billion, a twofold increase year-on-year, while subsequent stock issuances raised HKD 260 billion, up 270% [6] - The average daily trading volume in the Hong Kong secondary market increased by over 90% compared to the previous year, with the market capitalization nearing HKD 50 trillion, ranking third in Asia [6] Group 3: Future Trends - The trend of A-share companies seeking to list in Hong Kong is expected to continue, driven by the desire to enhance international visibility and attract global capital [6][8] - The Chinese Securities Regulatory Commission has issued measures to support leading domestic enterprises in listing in Hong Kong, indicating a favorable policy environment for such initiatives [8]

Core Viewpoint - The company has demonstrated significant revenue growth driven by its core products, cyclosporine eye drops and atropine sulfate eye drops, while implementing strategies to mitigate competitive pressures and optimize production capacity [1][2][3]. Group 1: Revenue Growth and Core Products - The company's revenue has consistently increased, with figures of 1.25 billion, 1.468 billion, and 1.943 billion from 2022 to 2024, and 536 million in Q1 2025, reflecting year-on-year growth rates of 32.42% and 53.24% [1]. - The net profit attributable to the parent company also rose, reaching 208 million, 240 million, 348 million, and 136 million during the same periods, with year-on-year increases of 44.54% and 285.96% [1]. - Cyclosporine eye drops, approved in June 2020 and included in the medical insurance directory in 2022, saw revenue growth from 448 million to 1.366 billion, projected to account for 100% of eye drop revenue in 2024 [1]. - Atropine sulfate eye drops, approved in March 2024, are the first product in China aimed at slowing the progression of myopia in children and are currently in a market monopoly phase [2]. Group 2: Competitive Landscape and Response Strategies - The industry is experiencing increased competition, with new products from companies like Hengrui Medicine and Kanghong Pharmaceutical expected to enter the market by mid-2025 [3]. - The company has established a comprehensive marketing system covering public hospitals, private eye care groups, retail pharmacies, and e-commerce platforms, with atropine eye drops available in approximately 17,000 retail pharmacies by mid-2025 [3]. - A professional promotion team of over 1,000 members has been formed, and core products have been included in more than 20 clinical guideline consensus documents [3]. - The company is expanding its research pipeline, with 78 projects under development, including 0.02%/0.04% concentration atropine and a biological agent for dry eye treatment [3]. Group 3: Production Capacity and Financial Health - The production capacity utilization rate for eye drops was 67.33% in 2024 and 60.37% in the first half of 2025, primarily due to new production lines ramping up and some outsourced production [4]. - The sales-to-production ratio remained high at 119.67% in the first half of 2025, indicating strong market demand [4]. - The company reported a decrease in accounts receivable turnover from 10.77 in 2022 to 8.94 in Q1 2025, but over 99% of accounts receivable are due within one year, with a collection rate of 93.73% [4]. - The company maintains a prudent approach to inventory management, with a provision for inventory impairment at 3.56%, higher than peers like Kanghong Pharmaceutical and Hengrui Medicine [4]. Group 4: R&D Investment and Future Plans - R&D expenditures from 2022 to 2024 were 190 million, 182 million, and 235 million, with capitalization ratios of 23.44%, 7.89%, and 6.22% respectively, primarily for clinical research on cyclosporine and atropine [5]. - As of June 2025, the company holds 73 invention patents and employs 271 R&D personnel, accounting for 11.17% of total staff [5]. - The company plans to raise 850 million through a private placement, with 650 million allocated for R&D center construction and 200 million for working capital, addressing current space constraints and aiming to add 280 R&D personnel over the next decade [6]. - The company clarified that adjustments to project investments were necessary due to rapid business growth, ensuring alignment with strategic planning without veering into real estate investments [6].

请务必阅读正文之后的信息披露和免责申明 重仓持股比例趋稳，全基有明显配置空间 ◆ 医药基金及全基医药行业配置情况 证券研究报告 2025年10月30日 医药生物 2025年3季度医药行业基金持仓结构分析 作者： 分析师 杨松 SAC执业证书编号：S1110521020001 分析师 刘一伯 SAC执业证书编号：S1110525080001 1 行业评级： 上次评级： 强于大市 强于大市 维持评级 （1）医药基金规模及份额：截至2025Q3，主动医药基金规模为2373亿元，相较于2025Q2环比提升457亿元。2025Q3被动医药基金规模 为1863亿元，环比提升429亿元，达到历史最高值。从基金份额上看，截至2025Q3，主动医药基金份额为976亿份，相较于2025Q2环比 减少67亿份。主动药基规模的提升，主要系股价上升。2025Q3被动医药基金份额为2503亿份，环比减少77亿份。 （2）医药基金重仓持股：从医药基金重仓持股比例看：2025Q3主动医药主题基金持仓前三行业分别为创新药（40%）/传统制药（34%） /CDMO（16%）。创新药中：信达生物、百利天恒、科伦博泰生物、康方生物等主动药基持仓均有 ...

Core Insights - Zhong Huijuan has become the richest woman in China with a wealth of 141 billion yuan, marking the first time a woman from the pharmaceutical industry has topped this list [2] - Zhong Huijuan's wealth primarily comes from Hansoh Pharmaceutical, where she and her daughter hold over 65% of the shares [3] Group 1: Personal Background and Achievements - Zhong Huijuan, aged 64, was born in Lianyungang, Jiangsu Province, and transitioned from being a high school chemistry teacher to an entrepreneur in 1996 [2] - She co-founded Hansoh Pharmaceutical with her husband, Sun Piaoyang, who is known as China's "pharmaceutical king" [2] - In the 2025 Hurun Rich List, Zhong Huijuan ranks 25th, while Sun Piaoyang ranks 38th with a wealth of 100 billion yuan [2] Group 2: Company Performance - Hansoh Pharmaceutical has successfully transformed from a traditional pharmaceutical company to an innovative one, with significant sales from new drugs like Ameluz, expected to reach 6 billion yuan in 2025 [3] - The company has secured two overseas deals for innovative drugs totaling over 3.5 billion USD in 2025, contributing to a stock price increase of over 100% since the beginning of the year [3] - Hansoh Pharmaceutical's market capitalization exceeds 200 billion HKD, ranking fourth among Chinese pharmaceutical companies [3]

Investment Rating - The report maintains a "Buy" rating for the education sector, particularly highlighting New Oriental's performance and potential recovery in overseas education [4]. Core Insights - New Oriental's revenue for Q1 FY26 reached $1.523 billion, a year-on-year increase of 6.1%, with the education segment (including cultural tourism) generating $1.366 billion, up 8.5% year-on-year [9][10]. - The report indicates that the growth rate of overseas education services has bottomed out, with expectations for recovery in the remaining quarters of FY26 [10]. - The company has announced a shareholder return plan, distributing $190 million in cash dividends and repurchasing up to $300 million in stock [9]. Summary by Sections 1. Overseas Education - The overseas education business has shown signs of recovery, with Q1 FY26 revenue from overseas exam training and consulting at $328 million, a 1% increase year-on-year, although the growth rate has slowed by 19 percentage points compared to the previous year [10]. - New business segments, including K9 non-academic training and learning machines, have maintained high growth, with Q1 revenue increasing by 15% to $403 million [10][11]. - The number of teaching locations increased to 1,347, representing a 24% year-on-year growth [10]. 2. Profitability Improvement - Despite a slowdown in high-margin study abroad services, the profitability of the literacy business has improved, offsetting the decline [11]. - Q1 FY26 Non-GAAP operating profit was $336 million, up 11.3% year-on-year, with an operating profit margin of 22%, expanding by 1 percentage point [11]. 3. Market Performance - The education index fell by 3.7% during the week, underperforming the Hang Seng Index by 4.3 percentage points, with a year-to-date increase of 19.3% [8]. - The report suggests a focus on Chinese education companies, particularly New Oriental, TAL Education, and others, as they show strong enrollment data for the fall semester [14]. 4. Key Company Updates - MGM China reported a record EBITDA of HKD 2.37 billion for Q3 2025, with net revenue of HKD 8.5 billion, a 17% year-on-year increase [16]. - The company continues to focus on high-end gaming and has seen significant growth in its market share [16].