Core Points - The National Healthcare Security Administration (NHSA) has announced a series of adjustments to the basic medical insurance directory and the first version of the commercial health insurance innovative drug directory, with the new directories expected to be officially published between October and November 2023 [1][2][6] Group 1: Policy Changes and Implications - The introduction of the commercial health insurance innovative drug directory is seen as a long-awaited opportunity for the industry, allowing for more market opportunities for high-priced drugs [2][4] - The NHSA emphasizes the importance of respecting the market position of commercial health insurance during the directory adjustment process, allowing insurance companies and industry experts to participate in price negotiations [5][10] - The new directory will include innovative drugs that exceed the basic medical insurance scope but have significant clinical value, with a focus on unique drugs approved between January 1, 2020, and June 30, 2025 [10][11] Group 2: Market Response and Growth Potential - The investment market has reacted positively, with innovative drug concept stocks rising by 7.76% within a week, indicating strong investor interest [7] - The self-funded market for innovative drugs in China is projected to grow from 320 billion yuan in 2024 to 1 trillion yuan by 2030, highlighting significant growth potential [6] - The introduction of the commercial health insurance directory is expected to provide more payment opportunities for high-priced "life-saving" drugs, particularly in the cell therapy and rare disease sectors [9][12][14] Group 3: Challenges and Industry Dynamics - Despite the positive outlook, not all players in the market will benefit equally, and the industry may face a significant shake-up akin to the centralized procurement process [8][25] - The NHSA's new policies aim to address issues of drug homogeneity and competition, with a focus on data openness to enhance the efficiency of innovative drug development [26][30] - The competitive landscape is expected to intensify, particularly for PD-1 drugs, as clinical performance will be linked to insurance renewals, increasing the pressure on companies to demonstrate efficacy [33]

Core Viewpoint - The Shanghai Stock Exchange Science and Technology Innovation Board Biopharmaceutical Index has shown strong performance, with significant increases in constituent stocks, indicating a positive trend in the biopharmaceutical sector [1][3]. Market Performance - As of July 11, 2025, the Biopharmaceutical Index rose by 1.23%, with notable gains from stocks such as Yifang Biotech (+10.31%), Shouyao Holdings (+8.34%), and Te Bao Biotech (+7.18%) [1]. - The Jiashi Science and Technology Medicine ETF (588700) also increased by 1.14%, marking its third consecutive rise [1]. Liquidity and Trading Volume - The Jiashi Science and Technology Medicine ETF recorded a turnover rate of 9.54% and a trading volume of 21.11 million yuan [3]. - Over the past month, the ETF has maintained an average daily trading volume of 33.32 million yuan, ranking first among comparable funds [3]. Fund Growth and Performance - In the last two weeks, the Jiashi Science and Technology Medicine ETF's scale increased by 17.56 million yuan, leading among comparable funds [3]. - The ETF's net value has risen by 37.70% over the past year, with a maximum single-month return of 23.29% since its inception [3]. Top Holdings - As of June 30, 2025, the top ten weighted stocks in the Biopharmaceutical Index accounted for 50.3% of the index, including companies like United Imaging Healthcare, BeiGene, and Huatai Medical [3][5]. Policy Support and Market Outlook - Recent policy documents have been released to support the high-quality development of innovative drugs, highlighting government backing for the sector [6]. - The number of innovative drugs in development in China has reached over 4,000, representing approximately 30% of the global total [5][6].

Core Viewpoint - Dongyangguang Pharmaceutical is set to become the first H-share company to undergo a merger and introduction listing, with its IPO application approved by the Hong Kong Stock Exchange, indicating significant advancements in technology, internationalization, and policy alignment [1] Group 1: Business Development - Dongyangguang's flagship product, Kewai, has generated substantial cash flow since its launch in 2006, with sales of Oseltamivir (including Kewai) maintaining the top position in the national market, accounting for 54.8% of the market share in 2024 [2][4] - The company's revenue from chronic disease treatment drugs has increased from 13.6% in 2022 to 26.6% in 2024, reflecting a strategic shift from reliance on flu medications to a diversified innovative pharmaceutical enterprise [4][6] Group 2: Innovation and R&D - Dongyangguang has established a robust R&D capability, focusing on innovative drugs since its inception, with advanced AI-driven models and a comprehensive R&D platform covering the entire lifecycle of chemical and biological drugs [6][8] - The company currently has 150 approved drugs globally and over 100 drugs in development, with several first-class innovative drugs already launched or in the application process in the Chinese market [7] Group 3: Internationalization Strategy - The company has signed a significant licensing agreement with Apollo in the UK worth $938 million, showcasing the international recognition of its drug portfolio [8] - Dongyangguang is one of the few companies capable of submitting applications to the US FDA and is expected to be the first to launch a long-acting insulin analog in the US without the need for Phase III clinical trials [8][9] Group 4: Market Position and Future Outlook - With the support of China's policies for innovative drug development, Dongyangguang is positioned as a leader in the global pharmaceutical market, leveraging its full-chain innovation capabilities to enhance R&D efficiency and international market access [9][11] - The company plans to integrate with Dongyangguang Changjiang Pharmaceutical to enhance its R&D, production, and commercialization capabilities, aiming for a successful listing on the Hong Kong Stock Exchange by August 2025 [11]

疫苗ETF跟踪的是疫苗生科指数，该指数由中证指数有限公司编制，从沪深市场中选取涉及疫苗研发、 生产、销售及生物科技领域的上市公司证券作为指数样本，覆盖疫苗产业链各环节。该指数旨在反映中 国疫苗及生物科技行业上市公司证券的整体表现，具有突出的专业性和成长性特征。 （文章来源：每日经济新闻） 消息面上，7月8日国家医保局联合卫健委发布《支持创新药高质量发展的若干措施》（以下简称《措 施》），提出16条全链条支持政策，同步推进商保目录制定以完善多元支付体系。 上海证券指出，高层高度重视医药创新发展，2025年政府工作报告提出建立商业健康保险创新药目录， 支持创新药发展。《措施》明确医保数据可用于创新药研发，探索为研发提供医保数据服务，推动真创 新和差异化创新。医保准入综合考虑基金承受能力、临床需求等因素，形成符合药品临床价值的支付标 准。商业健康保险与基本医保错位发展，探索同步结算。创新药进医保时间显著缩短，从获批到纳入医 保已降至1年左右，约80%的创新药可在上市2年内纳入医保。2024年简易续约药品平均降幅仅为1.2%， 近80%以原价续约。商业健康保险市场快速增长，2024年原保险保费收入达9773亿元，同比 ...

Core Viewpoint - The Hong Kong stock market is experiencing a collective rise, particularly in the innovative drug sector, with leading CXO company WuXi AppTec seeing a significant increase in stock price after its earnings report [1][3]. Group 1: Market Performance - The Hong Kong stock market is showing strong performance, with the innovative drug sector leading the gains, particularly the CXO segment [1]. - WuXi AppTec's stock rose over 13% following its earnings report, contributing to the overall strength of the CXO sector [1][3]. - The Hong Kong Stock Connect innovative drug ETF (159570) increased by 1.4%, with trading volume surpassing 1.6 billion RMB, and has attracted over 5 billion RMB in the last 60 days [1][3]. Group 2: Company Earnings - WuXi AppTec reported an expected revenue of 20.8 billion RMB for the first half of 2025, representing a year-on-year growth of approximately 20.64% [3]. - The net profit attributable to shareholders is projected to be around 8.561 billion RMB, showing a year-on-year increase of about 101.92% [3]. - Adjusted net profit is expected to be approximately 6.315 billion RMB, reflecting a year-on-year growth of about 44.43% [3]. Group 3: Industry Outlook - According to Fengzheng Securities, the innovative drug sector is expected to enter a new upcycle, driven by the recovery of domestic demand and potential interest rate cuts in the U.S. [4]. - The CDMO sector is anticipated to recover quickly due to its reliance on orders from large overseas pharmaceutical companies [4]. - Guotai Junan Securities indicates that the CDMO industry has reached a bottom and is poised for recovery, with strong performance expected in 2025 [4]. Group 4: Policy and Market Dynamics - The upcoming commercial insurance policy for innovative drugs is expected to open up long-term payment avenues for the sector [7]. - The National Healthcare Security Administration has emphasized comprehensive policy support for innovative drugs, which is likely to enhance their market potential [7]. - The commercial health insurance market in China is projected to grow significantly, with premium income expected to reach 977.3 billion RMB in 2024, a year-on-year increase of 8.2% [7]. Group 5: Investment Opportunities - The Hong Kong Stock Connect innovative drug ETF (159570) has a high concentration in innovative drug companies, with the top ten holdings accounting for nearly 72% of the index [8]. - The ETF has shown a remarkable performance, with a 62.78% increase in the first half of 2025, outperforming other medical indices [8]. - The underlying assets of the ETF are Hong Kong stocks, allowing for T+0 trading, which enhances liquidity for investors [8].

Core Insights - The innovative drug sector in both A-shares and Hong Kong stocks is experiencing strong performance, with significant gains in various companies such as Boteng Co., Changshan Pharmaceutical, and WuXi AppTec [1][2] - WuXi AppTec is expected to report a revenue of approximately 20.8 billion yuan for the first half of the year, marking a year-on-year growth of about 20.64%, with net profit expected to reach around 8.6 billion yuan, a year-on-year increase of approximately 101.92% [1] - The National Healthcare Security Administration has announced a plan for the adjustment of the national basic medical insurance drug catalog and the commercial health insurance innovative drug catalog for 2025, indicating a synchronized approach to drug catalog adjustments [1] Market Performance - The innovative drug ETF (515120) saw an increase of over 2%, marking its fourth consecutive day of gains, with a net inflow of 317 million yuan over the past ten trading days [2] - The Hong Kong innovative drug ETF (513120) also rose by over 1%, with a trading volume exceeding 4 billion yuan, making it the top-performing medical ETF in the market [2] - The leading medical ETF (560260) increased by over 2%, with major stocks like WuXi AppTec and Kelaiying leading the gains [2] Industry Trends - According to Guangfa Securities, China's innovative drug development is entering a phase of intensive policy benefits, with the number of original innovative drugs developed by Chinese companies expected to reach 3,575 by the end of 2024, surpassing the United States [2] - Global pharmaceutical giants are increasingly recognizing Chinese innovative drugs, with over 30% of collaborations involving upfront payments exceeding 50 million USD coming from China [2] - The focus should be on innovative drug companies with global competitiveness and the clinical value realization of their overseas products [2][3] Investment Opportunities - Aijian Securities highlights the trend of Chinese innovative drugs going global and maintains a bullish outlook on the medical technology sector for the year, emphasizing the importance of tracking ADCs and bispecific antibodies [3] - The upcoming mid-year report season presents opportunities to identify low-base, high-growth stocks, particularly in areas like medical devices, brain-computer interfaces, and AI in healthcare [3] Related Products - Innovative Drug ETF (515120) closely tracks the China Innovative Drug Industry Index, investing in companies involved in the research, production, and sales of innovative drugs [4] - Hong Kong Innovative Drug ETF (513120) tracks the Hong Kong Innovative Drug Index and supports T+0 trading, enhancing liquidity for investors [4] - Medical ETF Leader (560260) focuses on leading companies in the medical industry, including medical services and devices [4] - Pharmaceutical and Health ETF (159938) invests across various sectors in the pharmaceutical and healthcare industry [4]

Group 1 - The National Healthcare Security Administration and the National Health Commission released measures to support the high-quality development of innovative drugs, including 16 comprehensive support policies [1][2] - The measures include accelerating innovative drug research and development, improving the payment system, and establishing a commercial health insurance catalog for innovative drugs [1][2] - Domestic pharmaceutical companies have made breakthroughs in internationalization, with Dize Pharmaceutical's Shuwotini receiving FDA approval, marking it as the first domestic innovative drug approved in the U.S. for EGFR exon 20 insertion non-small cell lung cancer [1] Group 2 - The innovative drug sector is experiencing a hot market, driven by policy support and overseas trading catalysts, with a notable increase in the chemical pharmaceutical sub-sector, which saw a weekly increase of 5.03% [2] - The introduction of a commercial health insurance catalog for innovative drugs is a significant development, focusing on clinically valuable innovative drugs and improving the adjustment mechanism for the medical insurance catalog [2] - The CXO and life sciences upstream industry chain demand is recovering due to active overseas authorization transactions for innovative drugs [2]

周五（7月11日）早盘，医疗板块走强，A股最大医疗ETF（512170）场内涨1．49%，交投尤为活跃， 成交超5．6亿元。 成份股方面，CXO概念强势领涨，2200亿市值巨头药明康德涨停，凯莱英亦触板，九洲药业、康龙化 成大幅跟涨。 关注CXO和医疗器械，认准A股最大医疗ETF（512170）。聚焦"医疗器械+医疗服务"，与AI医疗相关 度高，覆盖6只CXO龙头股。场外联接基金（A类 162412 / C类 012323）。 关注创新药，认准国内首只药ETF（562050）。一站配齐"化学药+生物药品+中药"三大领域制药龙头， 既有创新药驱动高成长，又有中药降低指数波动，并且完全不含医疗和CXO。 风险提示：医疗 ETF 及其联接基金被动跟踪中证医疗指数，该指数基日为 2004.12.31 ，发布于 2014.10.31 。药 ETF 被动跟踪中证制药指数，该指数基日为 2011.12.30 ，发布日期为 2013.7.15 ， 2020- 2024 年分年度历史收益分别为： 41.61% 、 -9.10% 、 -21.09% 、 -3.70% 、 -6.53% ，指数成份股构成根据该 指数编制规则适时调整 ...

Core Viewpoint - The pharmaceutical sector is experiencing a surge in sentiment due to the strong performance of leading CXO companies, leading to significant increases in related ETFs in both A-shares and Hong Kong stocks [1][2]. Group 1: CXO Company Performance - WuXi AppTec expects to achieve revenue of approximately 20.8 billion yuan in the first half of 2025, representing a year-on-year growth of about 20.64% [2]. - The net profit attributable to shareholders is projected to be around 8.56 billion yuan, showing a year-on-year increase of approximately 101.92% [2]. - The adjusted net profit is expected to be about 6.31 billion yuan, reflecting a year-on-year growth of approximately 44.43% [2]. - The company continues to focus on its unique "integrated, end-to-end" CRDMO business model, expanding new capabilities and optimizing production processes [2]. Group 2: Market Trends and Investment Sentiment - The global healthcare investment and financing amount is showing signs of recovery, with a projected growth rate of 25.3% in total financing for 2024 [2]. - The recovery in orders for CXO services is evident, with major companies reporting significant increases in their order backlogs [5][6]. - The trend of Chinese innovative drugs going global is gaining recognition in the capital market, indicating a strong future for the industry [6]. Group 3: ETF Performance - The Biopharmaceutical ETF (159839) has seen a rise of over 2%, with significant inflows for three consecutive days [1]. - The Hang Seng Biotechnology ETF (513280) increased by 1.5%, marking it as the only ETF tracking the Hang Seng Biotechnology Index to receive net inflows this year [7]. - The Biopharmaceutical ETF focuses on industry leaders, enhancing its potential for higher returns and volatility [7].

7月11日，AH股创新药板块齐走高，A股药明康德涨停，常山药业涨超15%，港股药明康德、药明 合联均涨超10%。截至发稿，A股医药生物板块主力资金净流入超55亿元，其中，药明康德主力净 流入超10亿元，常山药业主力净流入超5亿元。 2025.07. 11 本文字数：527，阅读时长大约1分钟 作者 | 一财资讯 招银国际认为，短期来看，创新药估值受市场对出海交易预期影响而攀升，但需理性看待其股价上升 空间。创新药行业具有高风险、长周期、高回报的特征，出海交易的达成往往需要较长时间的研发积 累。 微信编辑 | 七三 推荐阅读 "黄金平替"，单日大跌6%！ 消息面上，7月以来，创新药板块频频迎来政策利好。昨日，国家医保局公布《2025年国家基本医 疗保险、生育保险和工伤保险药品目录及商业健康保险创新药品目录调整工作方案》，明确2025年 基本医保药品目录调整和商业健康保险创新药品目录制定将同步进行。而在1日，重磅政策《支持创 新药高质量发展的若干措施》印发。 中金公司表示，创新药产业投资趋势明确，向上传导或有产业链机会。长期看，中国创新药已进入渐 进式创新时代，开始具备国际竞争力；中期看，具备竞争力的临床数据和M ...