Core Insights - The Canadian government has launched the "Canada Global Influence Research Talent Program," committing $1.7 billion to attract up to 1,000 top international researchers over the coming years [1] - The initiative aims to enhance technological innovation, strengthen strategic industries, and ensure long-term economic security and competitiveness for Canada [1] Program Details - The "Canada Influence Research Chair" project has a 12-year budget of $1 billion to support universities and research institutions in recruiting world-class scholars, covering salaries and providing funding for experimental facilities and research platforms [1] - The "Canada Influence Emerging Leaders" project plans to invest $120 million over 12 years to attract early-career international researchers, injecting new ideas and innovative potential into Canadian research [1] - The "Canada Influence Research Infrastructure" fund will allocate $400 million over six years to build and improve research infrastructure, ensuring that newly recruited chair professors and core researchers have world-class working conditions [1] - The "Canada Influence Research Training Award" will provide $133.6 million over three years to support top international doctoral students and postdoctoral researchers to study and work in Canada [1] Context and Comparison - Prior to this initiative, top Canadian research institutions, such as the Toronto Academic Health Network and the University of Toronto, had already launched multi-million dollar recruitment plans targeting scientists affected by funding cuts in the U.S. [2] - The Canadian federal government has intensified its efforts, labeling this program as one of the largest talent recruitment initiatives globally, open to candidates from around the world, not just the U.S. [2] - The European Union is also actively seeking high-end research talent, having introduced a €500 million incentive program earlier this year to make Europe a "magnet for researchers" [2]

研究团队在模式生物秀丽隐杆线虫的肠道、神经元等组织中验证了这一方法。 衰老依赖于身体不同器官之间的长期、持续互动。传统基因操作技术只能让蛋白质产生或消失，难以分 辨同种蛋白质在不同组织中的差异作用。缺乏按组织、按剂量、按时间、贯穿生命周期的调控手段，因 此难以深入理解身体各部分如何推动衰老，如何彼此沟通，以及分子层面微小扰动如何随时间在全身扩 散。 在此基础上，团队工程化改造了多个版本的TIR1酶和降解标签，并在十万余条线虫中进行系统测试， 最终开发出一种更灵活的"双通道"AID系统。与传统方法不同，新系统不仅能控制蛋白质是否存在，还 能调节其剩余量，指定调控发生的位置与时间，同时不影响动物的正常进食、运动和生长。 西班牙巴塞罗那基因组调控中心和英国剑桥大学团队首次在活动物体内，对不同组织中的蛋白质水平进 行了"音量式"调控：将蛋白质含量像调节音量一样"调高"或"调低"，且具备高度可控性。他们的方法能 够在动物整个生命周期内使用，对研究衰老等全身系统性过程具有重要意义，有助科学家深入理解衰老 和疾病的分子基础。相关论文12日发表于《自然·通讯》杂志。 此次，团队在现有生长素诱导降解系统（AID系统）的基础上进 ...

全球首个经鼻眼底显微手术导航系统、全国首家人工视网膜医学芯片公司、全球首款0.01%低浓度阿托 品……这一系列突破性的"第一"，全部与一个硬核园区息息相关——中国眼谷。 近日，记者跟随中国残联走基层活动，来到位于浙江温州的中国眼谷小镇。2020年6月，由温州医科大 学附属眼视光医院（以下简称"眼视光医院"）与温州市龙湾区共同建设的中国眼谷正式开园。作为全球 首个眼健康科创、产业综合体，近年来，中国眼谷以科技创新带动产业升级，以成果转化促进产业壮 大，在"小眼球"上作出产业发展"大文章"。 在眼谷之瞳的展厅内，一台高分辨率视觉脑机接口设备吸引了投资者们注目。这台设备来自暖芯迦科技 （温州）有限公司，其搭载的脑机连接人工视网膜系统融合了多学科技术，包括脑机接口、人工智能和 工程仿生学等，适用于因各种原因导致的后天性视网膜严重器质性病变而失明者。 2022年，杭州暖芯迦电子科技有限公司董事长杨佳威带领团队入驻中国眼谷。目前，暖芯迦与中国眼谷 合作项目已于2024年下半年完成医疗器械型式检验。数据显示，该技术的移植分辨率超过1000像素，成 功移植后能够有效补偿患者视觉功能，帮助失明者生活自理。 眼视光装备、视觉光学 ...

Core Insights - The report indicates that in 2024, there are 816 potential unicorn companies in China, with 255 new entrants, over 90% of which are in cutting-edge technology sectors [1][2] - The report is the sixth edition published by the Great Wall Enterprise Strategic Research Institute, which has been releasing unicorn-related reports for nine consecutive years [1] Group 1: Potential Unicorn Companies - The number of potential unicorn companies has increased from 296 in 2019 to 816 in 2024, representing an approximate growth of 1.8 times [2] - Among the potential unicorns, 547 companies (67%) were established within the last five years and valued at $100 million, while 269 companies (33%) were founded 5-9 years ago and valued at $500 million [1] - In 2024, 747 potential unicorn companies belong to the cutting-edge technology sector, with 363 deriving their technology from universities and research institutions [2] Group 2: Industry Distribution - Potential unicorn companies are distributed across 42 sectors, with over 100 companies in the chip and innovative drug sectors, followed by 78 in new semiconductors and 52 in clean energy [2] - New entrants are found in 31 sectors, with more than 20 new companies in chip, new semiconductor, innovative drug, and power battery sectors, and over 50% of new companies in smart flight, smart hardware, power batteries, new materials, and synthetic biology sectors [2] - The proportion of potential unicorn companies in cutting-edge technology has increased from 56.4% in 2019 to 91.5% in 2024 [2]

秋季学期以来，我国多个省份全面启动中小学人工智能（AI）通识教育。AI进入中小学课堂，既有利 于培养能适应未来社会的现代公民，也有助于为国家储备科技创新的人才火种。不过，一些地方AI课 程在实践中出现的变形走样问题，也有待引起重视。 （文章来源：科技日报） 课程走样的背后有其现实原因，而胜任AI教育的师资力量不足是一大制约因素。尽管目前针对中小学 教师的AI培训不少，但覆盖面仍然有限，系统性和深度也有不足。从调研数据看，接触过神经网络、 深度学习的中小学教师凤毛麟角。此外，AI课是"强资源依赖型"课程，需要学生观察、实践、总结，他 们要写代码、设计机器人、部署本地模型，但并非所有学校都能提供相应的硬件设施和实验环境。同 时，一些培训机构渲染焦虑、推波助澜，把学AI与升学加分联系起来，使课程偏离了素养培育的轨 道，加重了学生负担，扼杀了他们对技术探索的兴趣。 要让AI课回归本质，需从师资建设、课程设计、观念引导三方面破局。在师资上，可建立"高校+企业 +学校"协同培训机制，借助社会力量补上师资短板；课程上，应摒弃知识灌输的老套路，根据不同年 龄特点采取不同教学方式，让孩子们自己动手做一次实验、写一行代码；在观念 ...

12月的黑龙江双鸭山寒风凛冽，双阳煤矿千米井下作业不停：0.8米高的极薄煤层工作面里，一台短矮 机身采煤机正精准地"啃噬"煤层。 它的"触角"实时捕捉地质数据，经5G信号以毫秒级速度传至地面调度中心，液压支架随之智能推移。 地面调度室里，技术人员轻点鼠标，井下全景同步呈现。这是如今极薄煤层智能开采的日常，而3年 前，这里还是"连转身都困难"的艰苦作业区。 我国薄煤层储量占总储量的20%，产量却只占煤炭总产量的10%左右。厚度小于1.3米的薄煤层，尤其是 0.7—1.0米极薄煤层，因开采难度极大，长期"沉睡"，但其中蕴含的"工业精粉"——被誉为煤炭"稀 土"的焦煤，是钢铁企业不可或缺的重要原料。 2021年，由黑龙江科技大学牵头的研发团队，在千米井下打响极薄煤层"夹缝掘金"智能开采攻坚战。 煤机"瘦身战" "薄煤层采煤，最难解的就是'小空间'和'大功率'这俩'死对头'。"在黑龙江科技大学实验室，吴卫东教授 一语道破关键矛盾。 煤层越薄，煤体通常越硬韧。采两米多厚的煤层，只需200千瓦总功率；可极薄煤层开采，装机功率达 500—900千瓦。 "作业空间就那么点儿，设备高了会被卡住，厚了挡煤流，薄了又扛不住大功率。 ...

Core Insights - The central economic work conference emphasized the importance of "accelerating the cultivation and expansion of new driving forces" as a key task for 2026, highlighting the urgency and proactivity in fostering new economic momentum [1][3]. Group 1: Strategic Significance - The strategic significance of cultivating new driving forces has become more pronounced, as the country faces external pressures and internal challenges, achieving qualitative improvements and reasonable growth in the economy [3]. - The need to shift away from traditional economic growth models and develop a modern industrial system that is self-controlled and competitive is underscored, with new quality productivity being a key driving force [3]. Group 2: Pathways and Measures - The conference proposed specific measures such as "formulating a plan for integrated development of education, technology, and talent," which aims to create a virtuous cycle of technology leadership, talent support, and educational assurance [4]. - The establishment of international science and technology innovation centers in regions like Beijing, Shanghai, and the Guangdong-Hong Kong-Macau Greater Bay Area is intended to enhance original innovation capabilities and attract top talent [4]. Group 3: Technological Foundation - The technological foundation for cultivating new driving forces is solid, with significant advancements in various sectors, including a nearly trillion-yuan scale in the biomanufacturing industry and continued global leadership in the electric vehicle sector [6]. - In 2024, China's national comprehensive innovation capability ranked 10th globally, with R&D expenditure exceeding 3.6 trillion yuan, and a notable increase in the contribution of the "three new" economy to GDP, which reached 18% [6].

Core Viewpoint - The successful launch of the "Hai Ji No. 2" deepwater jacket platform marks a significant advancement in China's deepwater oilfield development, with the full production of the second phase of the Liuhua oilfield project [1] Group 1: Project Overview - The Liuhua oilfield second phase development project is located in the Pearl River Mouth Basin and consists of the Liuhua 11-1 and 4-1 oilfields, with an average water depth of approximately 305 meters [1] - The project is designed to produce from 32 production wells, and since the first wells were put into operation in September of the previous year, daily crude oil production has reached 3,900 tons, setting a new production capacity record [1] Group 2: Historical Context - The Liuhua oilfield is China's first deepwater oilfield and has the largest proven geological reserves of reef limestone oil in the country, having been in production since 1996 [1] - To date, the Liuhua oilfield has produced over 20 million tons of crude oil, with an estimated 140 million tons of crude oil reserves still hidden beneath the seabed [1]

12月13日，中国华电集团有限公司四川分公司（以下简称"华电四川公司"）下属企业——四川凉山水洛 河电力开发有限公司"量子和后量子技术在水电集中监控系统关键技术研究"项目顺利通过阶段性评估， 标志着国内首个"量子水电站"工程在关键核心能力建设上取得阶段性重大进展，我国水电行业在前沿量 子技术融合应用方面实现新突破。 （文章来源：科技日报） 据悉，该项目坚持产学研用协同创新，由华电四川公司牵头，联合中国电信四川公司、中电信量子及国 电南自等单位共同开展关键技术攻关，选取四川凉山水洛河电力开发有限公司作为试点平台，率先推进 项目成果转化与应用，系统构建集自主可控、安全可靠于一体的新一代水电监控体系，全力打造国内首 个"量子水电站"工程，为我国能源安全与产业自主可控提供有力支撑。 为有效应对能源领域数字化转型进程中日益复杂的新型网络安全挑战，该项目团队积极探索前沿技术融 合路径，创新性地将量子通信及后量子密码技术引入水电核心监控系统，着力构建具备主动防御能力的 前瞻性安全架构，不仅为提升国家能源设施的安全可控水平提供了重要支撑，也为能源行业在高质量发 展进程中形成可复制、可推广的量子安全解决方案奠定了坚实基础。 四 ...

Core Insights - A recent analysis by NASA indicates that global ground-based astronomy research may face significant threats from satellite light pollution over the next decade, with approximately 96% of images from low Earth orbit observations potentially affected [1][2] Group 1: Satellite Impact on Astronomy - The number of satellites in orbit has surged to 15,000, up from just 75 in 2019, primarily due to decreased launch costs [2] - Ground-based observations, such as those from NASA's Webb Telescope, may be disrupted by reflected light from these satellites, rendering images unusable for research [2] - Previous studies have focused on the impact of satellites on ground-based astronomy, but the effects on space telescopes have been largely overlooked [2] Group 2: Future Projections and Solutions - NASA's Ames Research Center simulated the field of view changes for four space telescopes at an altitude of 800 kilometers as satellite numbers increase, including NASA's Webb and SPHEREx, ESA's ARRAKIHS, and China's planned survey space telescope [2] - It is projected that 560,000 satellites will be operational in the future, potentially polluting 39.6% of images from the Webb Telescope and 96% of images from the other three telescopes [2] - The average number of satellites observed by the Webb Telescope is estimated to be 2.14, while SPHEREx may see 5.64, ARRAKIHS 69, and the survey telescope 92 [2] - A potential solution proposed is to deploy satellites in orbits lower than those of the telescopes, although this could negatively impact the Earth's ozone layer [2]