据《自然》杂志24日报道，美国斯托瓦斯医学研究所团队首次精确定位了人类染色体在形成罗伯逊易位 时的融合点。这项研究具有里程碑式的意义，不仅揭示了这类染色体融合是如何形成并保持稳定的，还 指出曾被认为是"垃圾"的重复DNA，可能在基因组组织和进化中发挥核心作用。 人类染色体通常被描绘成两两配对的"整齐队列"。但在大约每800人中，就有一人出现不同寻常的情 况，即两条染色体"牵手"融合，形成一种特别的结构，这就是所谓的罗伯逊易位。这种现象长期以来困 扰着科学家。 罗伯逊易位携带者往往并不自知。他们大多健康，但可能会出现不孕或流产的情况。当他们有子女时， 孩子罹患唐氏综合征的风险也会升高。 此次，团队利用一种称为"长读长测序"的DNA测序技术，首次获得了完整的罗伯逊易位染色体序列。 与传统测序方法不同，长读测序能读取高度重复的DNA区域，使科学家看清了此前难以解析的"盲 区"。团队比较了3条罗伯逊易位染色体与正常染色体，发现它们的断裂点均位于一种称为SST1的重复 DNA序列中。当这些SST1序列在细胞核仁中靠近时，可能发生融合，形成罗伯逊易位染色体。 罗伯逊易位的形成机制是两条染色体的长臂融合，而短臂丢失。这样会 ...

Core Insights - A new dual-mode CRISPRa/i gene editing system has been developed by South Korean scientists, allowing simultaneous "activation" and "suppression" of different genes, overcoming the limitations of existing CRISPR technology which primarily focuses on gene suppression [1][2]. Group 1: Technology Development - The new system was developed through collaboration between the Korea Advanced Institute of Science and Technology and the Korea Institute of Chemical Technology [1]. - The dual-mode gene scissors enable precise control of gene expression, akin to an electrical switch, which is crucial for optimizing metabolic pathways in synthetic biology [1][2]. Group 2: Performance Metrics - In experiments, the new system demonstrated significant performance improvements: protein expression levels increased by 4.9 times during activation experiments, while protein production decreased by 83% during suppression experiments [2]. - The system successfully achieved simultaneous regulation of two genes, with one gene's activity increased by 8.6 times and the other gene suppressed by 90% [2]. Group 3: Industry Implications - This dual-mode CRISPR system is expected to provide powerful tools for metabolic pathway optimization, gene network research, and bacterial functional genomics, potentially enhancing the efficient production of high-value compounds, biofuels, and pharmaceuticals [2].

在2024年末举行的"人工智能之旅"国际会议上，俄罗斯总统普京表示，人工智能（AI）技术注定将成为 实现国家发展目标、增强国防实力、确保经济和社会部门高质量发展、公共管理以及创新增长的关键资 源。为了成功应对这些挑战，俄罗斯不仅必须在技术创造方面，而且必须在技术应用规模方面成为全球 领先者，使其渗透到生活的方方面面。 AI技术的全面普及或许还有待时日，但AI确实已渗透到了俄罗斯生活的方方面面，并成为中俄合作的 热门关键词。9月初随普京访华的俄副总理切尔内申科在谈到中俄两国合作时特别强调，"AI领域是最具 合作前景的方向之一"。俄AI行业领军人物——俄罗斯联邦储蓄银行（以下简称"俄储蓄银行"）第一副 董事长亚历山大·维德亚欣在近期举行的东方经济论坛上也特别谈到了与中国开展AI领域合作的进展， 以及对AI领域发展的展望。 俄人工智能市场：潜力巨大，前景广阔 俄罗斯的AI市场究竟有多大？对于这个问题，维德亚欣的答案是：俄罗斯AI市场最低估值达50亿—70 亿美元，俄AI市场蕴含着巨大潜力和广阔前景。 从市场规模增长数据来看，2025年俄AI应用市场规模同比2023年增长89%，其中企业级解决方案占比首 次超越消费级 ...

Core Insights - The article highlights the advancements in China's information and communication industry, showcasing innovations in 5G technology and artificial intelligence, as well as the importance of integrating digital and physical infrastructures for future growth [1][2][3][4]. Group 1: Industry Developments - As of August 2023, China has established 4.646 million 5G base stations and has 1.154 billion 5G mobile phone users, maintaining a global lead in key metrics such as 5G user penetration and gigabit optical network coverage [2]. - The integration of 5G technology into 86 categories of the national economy is accelerating, with a focus on enhancing production core processes [2]. - The industry is actively pursuing technological innovation, with a push for the development of 5G-A product systems and the advancement of 6G technology [3]. Group 2: Technological Innovations - The introduction of a new disaster-resistant base station by China Tower, capable of withstanding level 8 earthquakes and level 12 winds, demonstrates the commitment to ensuring communication continuity during extreme disasters [1]. - The event showcased the integration of AI and 5G technologies, with applications such as intelligent robots performing alongside human dancers, enabled by ultra-low latency 5G networks [3][4]. - China Telecom and China Mobile are developing comprehensive computing capabilities, including quantum computing and AI models, to meet diverse industry needs [4]. Group 3: Future Outlook - The industry anticipates a shift towards AI-driven applications, with predictions that by 2030, the number of intelligent agents will surpass traditional apps, creating new opportunities for operators [4]. - There is a strong emphasis on fostering the integration of AI and manufacturing, aiming to cultivate a new generation of industrial intelligent agents [5].

17.5万立方米LNG运输船配备新型LNG双燃料低速主机及ICER系统，燃油、燃气模式均满足国际海事组织最高排放标准；采用创新双艉鳍线型设计，配合 空气润滑系统，显著提升水动力性能，增强推进系统安全冗余；液货舱采用GTT Mark Ⅲ薄膜型围护系统，日蒸发率仅0.085%；同时配置再液化装置，可高 效处理LNG蒸发气。一次满载运输的LNG，能满足大连市一个半月的民生与工业用气需求，且可停靠全球绝大多数大型LNG岸站，具有卓越的适港性和船 岸兼容性。 科技日报记者 张蕴 24日，中国船舶集团旗下大连造船为招商轮船建造的17.5万立方米液化天然气（LNG）运输船正式命名交付。这艘总长295米的"海上超级冷冻车"由大连造 船完全自主研发设计，集成了多项国际前沿技术。它的成功交付，标志着中国造船业在"皇冠上的明珠"领域再下一城。 LNG运输船是国际造船业公认的"高技术、高难度、高附加值"产品，其核心的液货围护系统被称为"在零下163摄氏度的极寒中'绣花'"，全球仅有少数几家船 厂掌握核心建造能力。大连造船首次涉足该领域，便实现了"首船即达标、交付即领先"的突破。 目前，大连造船手持LNG运输船订单已达17艘，实现开工 ...

Core Viewpoint - China Unicom launched the "Bailian Qiantong Wan (Anhui) Qizhi" series of activities at the 2025 World Manufacturing Conference, showcasing its innovation capabilities in industrial internet and artificial intelligence [1][3]. Group 1: Event Overview - The event was themed "Digital Intelligence Empowerment: AI Connecting the Future" and highlighted China Unicom's commitment to enhancing the smart transformation of manufacturing in Anhui [1]. - The series of activities aims to promote comprehensive connectivity in the era of the Internet of Everything, emphasizing the integration of IT, OT, and CT to empower the intelligent upgrade of Anhui's manufacturing industry [3]. Group 2: Strategic Initiatives - Anhui Unicom is focusing on "5G + Industrial Internet" as a key strategy, leveraging its self-developed platforms and models to create benchmark factories such as Tongling Nonferrous Metals and Midea [3]. - The company plans to accelerate the deep integration of AI with 5G and industrial internet, collaborating with ecological partners to build a new industrial ecosystem named "Wanmei Zhilian" [3]. Group 3: Technical Insights - Experts from China Unicom presented insights on the development framework of industrial internet, innovative applications of smart technology, and the support of data infrastructure in the field of industrial digitalization [4]. - Anhui Unicom aims to align with the province's strategic positioning of "Three Lands and One Area," enhancing technological innovation and collaboration to drive the intelligent transformation of the manufacturing sector [6].

9月20日至23日，以"智造世界·创造美好"为主题的2025世界制造业大会在安徽合肥举行。来自全球40多 个国家和地区的代表齐聚一堂，通过4场重大活动、6场项目对接活动和23场专项活动，共同探讨制造业 的未来发展路径。 从首次亮相的智能机器人展区，到多项颠覆想象的"高精尖"首发成果；从持续领跑的智能网联新能源汽 车，到闪亮登场的国际领先产品……中国制造业以持续迭代的创新技术，为全球制造业高质量发展提供 中国方案、贡献中国智慧。 智能机器人上演"总动员" 在本届大会首设的智能机器人展区，智能机器人上演"总动员"。展区以"机器人大道"为主线，实景还原 城市街区风貌，生动展示机器人在真实工业和生活场景中的广泛应用。 该展区汇聚40家智能机器人企业，围绕工业园区、生活社区和创新社区三大板块，打造十大应用场景， 以"单场景演示+多场景社区+动态表演+全生态展示"等形式，全面呈现智能机器人的典型应用、核心零 部件与创新平台。 在"机器人大道"上，工业机器人与服务机器人各显其能：一侧的工业机器人展现高精度作业能力，另一 侧的人形机器人则提供多样化便民服务。 在机器人商店里，售货员是由合肥零次方机器人有限公司研制的人形机器人 ...

Core Insights - A team from Linköping University in Sweden has developed artificial neurons made from conductive plastics that can simulate advanced functions of biological neurons, exhibiting up to 17 key characteristics [1][2] - This breakthrough in artificial neurons opens up vast prospects for next-generation implantable sensors, medical devices, and advanced robotics [1] Group 1: Technological Advancements - The research demonstrates that organic electronics are not merely flexible alternatives to silicon-based electronics but have the potential to achieve new forms of neuromorphic computing, effectively connecting biology and electronics [2] - The team has simplified the basic structure of artificial neurons, previously achieving 15 out of 22 key characteristics of biological neurons, but the earlier design relied on multiple components, limiting practical applications [2] Group 2: Functional Capabilities - The newly developed artificial neurons can perform a function called "anti-coincidence detection," activating only when one input signal is present while another is absent, a mechanism widely found in the human nervous system [1] - This capability enables the integration of more sensitive and intelligent tactile feedback in prosthetics or robotics in the future [1] Group 3: Biological Compatibility - The new artificial neurons are not only more powerful but also comparable in size to real human nerve cells, demonstrating high biocompatibility and integration potential [2] - This development represents one of the simplest and most biologically relevant artificial neurons reported to date, paving the way for direct integration into living tissues or soft robotic systems [2]

记者9月22日从中国农业科学院获悉，该院农业基因组研究所作物组学大数据与应用创新团队发现了小 麦抗病早熟的"双效开关"。这一发现为改良小麦赤霉病抗性和培育抗病新品种提供了重要的基因资源。 相关研究成果日前发表在国际期刊《自然·通讯》上。 这一研究为培育抗病性强且生长周期短的小麦品种提供了新思路。张翠军说："在农业生产中，抗病性 强的小麦品种能够减少因病害造成的损失，而生长周期短的品种则可以更好地适应不同的气候条件和种 植制度，有助于提高农业生产的效率和灵活性。"（记者马爱平） 在此次研究中，团队鉴定出了一个关键基因——TaFAH，该基因能够显著抑制禾谷镰孢菌的侵染。团队 发现，当人为提高小麦中TaFAH的表达水平时，小麦抗病性显著增强；与此同时，禾谷镰孢菌的菌丝生 物量以及呕吐毒素含量都有所减少。 "TaFAH的作用不仅体现在提高小麦抗病性方面。研究还发现，与对照组相比，TaFAH过表达株系的抽 穗期提前了约10天。这一发现表明，TaFAH是一个能够同时调控小麦抗病和早熟的'双效开关'。"张翠 军说。 论文通讯作者、中国农业科学院深圳农业基因组研究所研究员张翠军介绍，小麦赤霉病是由禾谷镰孢菌 引起的一种毁灭性 ...

记者9月23日获悉，西湖大学理学院张鑫教授团队通过调控荧光蛋白的发光时间（即荧光寿命），开发 出具有不同寿命的荧光蛋白变体。相关研究成果日前刊发于《细胞》期刊。 基于上述研究，张鑫团队成功构建出包含28个不同荧光寿命突变体的"彩虹"工具库。这一研究成果有望 大大拓展科学家在活细胞内进行实时、动态、多靶标观测的能力，为理解生命复杂体系提供强大的技术 平台。（记者刘园园） 在此过程中，电子可通过两种方式回到基态：一是通过发射光子的形式辐射能量，发出荧光，即辐射跃 迁；二是通过与其他分子碰撞等方式转移能量，即非辐射跃迁。荧光寿命，指电子在激发态"停留"的平 均时间。这个时间通常在纳秒级别（1纳秒等于十亿分之一秒），是每种荧光分子独有的"身份特征"。 为调控荧光蛋白的荧光寿命，研究团队尝试对发色团周围的氨基酸进行"饱和突变"——将其随机替换为 其他19种氨基酸。 经过数万个突变体的高效筛选，他们最终获得了一批荧光寿命显著差异的荧光蛋白突变体。来自同一个 模板的突变体，其激发条件和发光颜色都没有改变，只是寿命不同。张鑫团队将这类新型荧光蛋白命名 为"时间分辨荧光蛋白"。 "我们计算发现，寿命更短的突变体，往往具有更快的 ...