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「吉美瑞生」获3.5亿C轮融资,干细胞疗法已落地乐城“先行先试”|36氪首发
3 6 Ke· 2026-02-11 00:03
Core Insights - Regend Therapeutics Limited has completed a C-round financing of 350 million RMB, with new investors including Yuze Capital and Hefei High-tech Investment, among others, and existing investors continuing to support the funding [1] - The funds will be used to advance clinical applications of core products related to stem/progenitor cells [1] Company Overview - Founded in 2015, Regend Therapeutics focuses on regenerative medicine using progenitor cells to repair and enhance human organs through innovative cell gene therapy products [1] - The company is led by founder Zuo Wei, a PhD in cell biology from Tsinghua University, and CEO Zhang Ting, a PhD in biology from Tsinghua University [1] Product Pipeline - Regend's core pipeline includes REGEND001 (autologous lung progenitor cells) and REGEND003 (autologous kidney progenitor cells), both of which have entered clinical stages [1][2] - REGEND001 targets chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), with clinical trials showing significant improvements in lung function and quality of life [3] - REGEND003 aims to treat diabetic kidney disease (DKD) and has received approval for Phase I clinical trials, utilizing a non-invasive method to obtain kidney progenitor cells from urine [4] Clinical Development and Commercialization - Regend plans to initiate Phase III clinical trials for REGEND001 in 2026, focusing on COPD and IPF, and has received orphan drug designation from the FDA for IPF [3] - The company has already begun clinical transformation and commercialization of its therapies in the Boao Lecheng International Medical Tourism Pilot Zone, with over 140 cases completed since last May [4][5] Investor Perspectives - Investors view Regend as a leading innovative company in the regenerative medicine sector, with a strong competitive advantage and a clear path to commercialization [6][7] - The completion of the C-round financing is expected to support clinical advancement, international strategy, and the establishment of a commercial system [6]
压力山大,做啥错啥,该怎么办?
3 6 Ke· 2026-02-11 00:03
压力山大,往往做啥错啥,此时更难控制自己情绪,一点小事就炸毛,简单事情也做不好。持续很长时间、看不到结束的压力还会损坏我们的 健康。长期压力与心脏病、高血压、抑郁症等疾病都有关,还有可能损害我们的大脑。如何避免这一切?也许你应该开始锻炼身体~ 在解释锻炼如何缓解压力之前,我们需要先了解一下神经系统、大脑和压力之间的关系。 关于压力的神经系统 人类有三个相互协调的神经系统帮助我们应对压力: 第一个是躯体神经系统。它是神经系统的一部分,便我们能够对身体发出类似「站起来,跑」的命令,它使我们动起来以逃避危险。 第二个是自主神经系统。自主神经系统包括两个部分,它们各自在非常不同的情况下发挥作用。 第一个部分被称为交感神经系统,它负责我们的战斗或逃跑反应。当紧急情况出现时,比如遇到猛兽、地震等,交感神经系统会被激活。它会增加我们的 心率、呼吸频率,放大瞳孔(为了更好地看清猛兽),向血液里释放葡萄糖,控制血液流向重要的肌肉群,因此身体和特定的肌肉能够很快获得能量(为 战斗或逃跑做好准备)。 自主神经系统的另一部分被称为副交感神经系统。当我们放松时这个系统就会开始工作,它可以降低人的心率和呼吸频率,让瞳孔缩小,把血液输送到 ...
GLM-5架构细节浮出水面:DeepSeek仍是绕不开的门槛
3 6 Ke· 2026-02-10 23:57
Core Insights - The article discusses the imminent release of new AI models in the Chinese market, particularly focusing on the GLM-5 model from Zhipu AI, which is expected to leverage advanced technologies and compete effectively in the AI landscape [1][16]. Group 1: Model Development and Features - The GLM-5 model has been linked to multiple technical platforms, indicating a strong collaborative effort in its development [2][4]. - GLM-5 incorporates a 78-layer Transformer decoder with a total parameter count of approximately 745 billion, which includes a mixture of dense and sparse architectures [6][8]. - The model utilizes a hybrid expert (MoE) architecture, activating only a small fraction of its parameters during inference, which enhances efficiency while maintaining performance [9][10]. Group 2: Technological Innovations - The integration of DeepSeek's Sparse Attention (DSA) mechanism allows GLM-5 to handle long sequences more efficiently, reducing computational costs significantly [12][13]. - Multi-Token Prediction (MTP) technology is employed to accelerate token generation, allowing the model to predict multiple tokens simultaneously, which is particularly beneficial for structured text generation tasks [15][16]. - The model's architecture reflects a shift towards efficiency over sheer parameter count, indicating a trend in the AI industry towards optimizing performance rather than simply increasing size [9][17]. Group 3: Market Position and Challenges - GLM-5 is expected to excel in code generation and logical reasoning tasks, positioning it competitively in software development and algorithm design [16]. - However, the model currently lacks multi-modal capabilities, which may limit its applicability in creative AI-generated content (AIGC) scenarios, especially as competitors advance in this area [16]. - The article highlights a broader industry trend where companies are moving towards open-source technology integration, emphasizing efficiency and practicality in AI model development [16][17].
春晚+冬奥+电影+AI,抖快春节营销的“内容之战”
3 6 Ke· 2026-02-10 23:57
短视频无疑是新年俗的流量基站。 在当下,由于可动用多元媒介开发互动型节目,短视频平台越来越爆发出强大的节点型文娱内容生产能量。那马年的短视频年味内容又有什么新打法、新 爆点? 拿下春晚,联动冬奥 这届年轻人早就在过一种很新的年: 抖音上用AI手搓几款抽象拜年短视频、快手上炫拍个非遗打铁花或潮汕英歌舞,听说春节唯有整点这些新活儿,你才能跟上00后的聊天节奏! 临近丙午马年,作为新年俗的主阵地,抖快早就开始置办起今年春节期间的全景内容营销盛宴。抖音早早于2月2日就官宣成为总台新媒体《竖屏看春晚》 独家合作伙伴,9日起又携手《飞驰人生3》沈腾、《镖人》吴京等多部春节档影片主创们接力直播"卖电影";快手同样在2月9日重磅官宣与总台春晚达成 全程内容合作,且借势谷爱凌夺银等冬奥热点在吉林长春落地了由千问AI冠名的《快手冬运会》、解锁了王濛那艺娜等人组成的米兰观赛团直播"聊冬 奥",此外快手春节的内容动作还包括明星晚会、庙会年俗、新潮次元、好剧好戏、知识输出等…… 近几年每逢春节前夕,抖快都会提前拉出为期一个多月的新春直播内容排播计划,今年两边都很默契取消了相关企划,但围绕春晚、冬奥、电影、AI、 短剧等内容版块发起的新 ...
进入2026年,AI开始显露残酷一面
3 6 Ke· 2026-02-10 23:37
Core Insights - The article discusses the evolving landscape of AI, predicting a shift towards a three-tier ecosystem consisting of AI assistants, vertical AI services, and specialized skills [1][7]. Group 1: Industry Trends - The year 2025 is seen as a turning point for AI, with significant trends emerging, including the rise of AI tools and services that have rapidly gained popularity [2][3]. - New AI habits and models have quickly matured, such as the replacement of traditional search engines with AI assistants for obtaining answers [4]. - The rapid rise and fall of star products and companies in the AI space reflect a dynamic market, where trends can shift dramatically within a year [5][6]. Group 2: Company Strategies - Major companies are expected to continue their strategic shifts towards AI, with significant resource investments to solidify their positions in the AI service ecosystem [10][12]. - ByteDance has made substantial organizational adjustments to focus on AI, achieving significant user engagement with its AI products [10][12]. - Alibaba is integrating AI into its consumer-facing services, leveraging its existing ecosystem to enhance its AI offerings [12][13]. - Tencent is also investing heavily in AI, with expectations for leadership changes to drive its AI strategy [12][13]. Group 3: Future Developments - The emergence of more AI hardware products is anticipated, which will support various vertical AI services and enhance user experiences [9][10]. - The competition among major players for AI service dominance is expected to intensify, with companies like Baidu making organizational changes to remain competitive [13][14]. - The second tier of the AI service ecosystem will see participation from both established and emerging companies, focusing on niche AI services [14][15]. Group 4: Creator Ecosystem - The article highlights the potential for a new ecosystem of creators enabled by AI tools, allowing ordinary individuals to engage in content creation and innovation [18][19]. - The rise of AI-driven platforms is expected to democratize content creation, providing tools that empower users to generate unique outputs [19][20].
李书福加持、资本热捧,“中国版马斯克”横空出世?
3 6 Ke· 2026-02-10 23:31
Core Insights - The article discusses the emergence of a new player in the AI industry, particularly focusing on the leadership of Yin Qi at Jieli Technology and the launch of the new model Step 3.5 Flash by Jiyue Xingchen, which aims to integrate AI into the physical world [2][9][35] Group 1: Industry Trends - The domestic large model sector is experiencing intense competition, with major players releasing new model versions and engaging in aggressive talent acquisition, including a combined investment of 4.5 billion yuan for recruitment during the Spring Festival [2] - The current landscape indicates a shift towards physical AI, as companies like OpenAI and Google are investing in robotics and integrating AI into hardware, marking a transition from virtual to physical applications of AI [4][28] Group 2: Company Developments - Jiyue Xingchen, under Yin Qi's leadership, is the only company in China focusing on both large models and terminal applications, aiming to bring AI into the physical world [2][9] - The company has secured 5 billion yuan in B+ round financing, setting a record for the largest single financing in the Chinese large model sector in the past year [9][25] Group 3: Leadership and Vision - Yin Qi, a veteran in the AI field, has shifted his focus from his previous company, Megvii, to the automotive sector, believing that AI combined with vehicles represents a significant opportunity for growth [9][12][28] - His strategy emphasizes the importance of profitability and creating a closed-loop system for AI applications, which he believes is essential for long-term success [14][25] Group 4: Technological Innovations - Jiyue Xingchen's new model, Step 3.5 Flash, is designed for intelligent agents, offering low latency and high-speed capabilities, which are crucial for applications in autonomous driving and smart cabins [26][29] - The company has achieved deep compatibility with several domestic AI chip manufacturers, ensuring a closed-loop for domestic computing power [27] Group 5: Market Positioning - The collaboration between Jiyue Xingchen and Jieli Technology aims to create a comprehensive intelligent driving system, which has already been implemented in over 300,000 vehicles [29] - Yin Qi's approach focuses on partnering with leading automotive companies to establish a strong market presence and build a data-driven feedback loop for continuous improvement [32]
字节Seedance 2.0火了,海外博主锐评:一周前我还在看好可灵……
3 6 Ke· 2026-02-10 23:25
Core Insights - ByteDance has launched its AI video generation model Seedance 2.0, which has been described as a "game changer" in the industry, showcasing significant advancements in video generation capabilities [1][4][23]. Group 1: Product Development and Features - Seedance was initially developed as a text-to-video model in 2023, undergoing two years of internal testing before its public release in June 2025 [1]. - The model has undergone multiple updates, with three major versions (1.0, 1.0 pro, 1.5 pro, and 2.0) released in the last eight months, culminating in its current iteration, Seedance 2.0 [1]. - Seedance 2.0 is praised for its ability to generate complex multi-shot scenes with synchronized sound effects, music, and multilingual dialogue, earning it the title of "new king" in AI video models [4][9]. Group 2: Market Reception and Impact - The launch of Seedance 2.0 has generated significant buzz in both domestic and international markets, with notable creators and media outlets discussing its capabilities [4][6]. - Global media coverage has highlighted Seedance 2.0's role in establishing ByteDance as a key player in the global AI video market, with early users expressing high praise for its innovative features [9][14]. - The model has been compared favorably against competitors like OpenAI's Sora and Google's Veo, with reports indicating it surpasses them in video generation speed and narrative control [14][28]. Group 3: Competitive Landscape - The competitive landscape in AI video generation is intensifying, with other Chinese companies like Kuaishou also launching their models, such as Kling 3.0, which Seedance 2.0 has outperformed [14][30]. - Analysts believe that Seedance 2.0 could enhance ByteDance's valuation in the capital markets, reflecting its potential impact on the company's financial performance [14]. - The advancements in Seedance 2.0 signify a broader trend of Chinese tech companies leading in AI innovation, potentially reshaping the global technology landscape [30].
人类画了100年的脑图,AI仅用几小时,还绘制出新脑区
3 6 Ke· 2026-02-10 23:25
好消息,AI也可以帮科学家画脑图了! 近期,一个来自加州大学旧金山分校的神经科学团队提出了一种新的机器学习算法——CellTransformer,仅花费几个小时就完成了对5只小鼠大脑图谱的 分类和绘制工作。 2020年发布的艾伦小鼠脑通用坐标框架(Allen Mouse Brain Common Coordinate Framework),就是采用这种方法画出来的。 这五只小鼠大脑的基因数据中包含1040万个细胞,每个细胞包含数百个基因。但通过这一创新性算法,研究团队不仅清晰地划分出了小鼠大脑内的已知区 域,还绘制出了新的脑区。 更夸张的是,这项技术很可能会进一步应用于人类。 画脑图的最新黑科技:CellTransformer 大脑图谱绘制是一门古老的学科,过去画脑图的方法相当复杂,需要科学家用铅笔在脑部图像上画线,连接不同区域。 这幅脑图基于1675只小鼠的脑部数据,涵盖了1000多个不同的脑区,具有很高的价值。 但这类手工特征很强的图谱也不可避免地存在一个问题:具有主观性。 宾夕法尼亚州立大学医学院的神经解剖学家金永洙(Yongsoo Kim)表示,当他向资深专家请教如何画脑图时,对方往往只有一句话:"这 ...
具身智能苦等“ChatGPT时刻”
3 6 Ke· 2026-02-10 23:22
Fast Reading 在人工智能的诸多分支中,具身智能是近一年间被高频提及的方向之一。 从工业机器人到服务机器人,从自动驾驶到人形机器,各条技术路线每隔一段时间就会被寄予一次"通用智能入口"的期待。 但与算法驱动的软件革命不同,它始终被现实世界的摩擦力拖慢节奏。 如果只看公开视频,具身智能的公共叙事几乎被同一组类似的画面占据:机器人跑得更稳了,抓得更准了,动作更连贯,任务更复杂。融资在加速,模型 在迭代,具身智能似乎正处在一条确定无疑的上升曲线。 成功被循环播放,失败被剪掉——在实验室之外,另一种叙事同时存在:部署成本、稳定性、维护复杂度,仍在反复拉长商业化的时间表。 2月10日,原力灵机的首次技术开放日在北京中关村国家自主创新示范区展示中心举行。 原力灵机发布了三款核心产品:具身原生大模型 DM0、具身原生开发框架 Dexbotic 2.0、以及具身原生应用量产工作流 DFOL。这也是原力灵机成立近一 年来,公司核心团队第一次集体公开亮相。 在当天的"Physical Al Next 圆桌论坛"上,来自产、学、研的五位嘉宾花了约一半的时间,讨论一个问题: 具身智能的ChatGPT时刻何时到来? 具身智能 ...
中文版Nano Banana来了?Qwen-Image-2.0炸场:1K长文本硬吃,中文生图彻底不拧巴了
3 6 Ke· 2026-02-10 23:05
文本一长就糊、指令一杂就撂挑子、遇到中文更是一整个变形freestyle…… 「AI生图」的这点苦,到底有谁懂啊!!! 停,不用拧巴了,因为现在的AI,已经能稳稳吃下1K token的超长文字指令了: 你以为到这儿就结束了,NONONO!因为它还能——多图编辑。 随手丢给了它一张照片,人家直接给我甩出一组影棚级的9宫格写真!!(诶,突然感觉怒省一笔钱… 复杂指令也不在怕的,最近OpenClaw贼火,我索性让AI直接帮roll出一个赛博信息图海报(你就说牛不牛吧): 中文渲染表现也不孬,《兰亭集序》这种公认的高难度文本,这AI居然能做到文字1:1还原,排版、笔锋都在线: 刚才帮我干活的这位,正是阿里刚刚发布的新一代图像生成及编辑模型——Qwen-Image-2.0。 1K token长文本、复杂指令、中文渲染、图片编辑、2K分辨率一次性梭哈,连国际评测里的表现都已经冲到了仅次于Nano Banana Pro的位置。 不废话,这个中文版Nano Banana到底能不能打,咱实测见真章!!! Qwen-Image-2.0 一手实测 复杂指令理解准,1K token文本玩得转 在AI生图界,最让人崩溃的倒不是写Pro ...