关于云南白药集团股份有限公司 北京德恒（昆明）律师事务所 2024 年度股东大会的 法律意见 北京德恒（昆明）律师事务所 Beijing DeHeng Law Offices (KunMing) 云南省昆明市西山区西园路 126 号"融城优郡"B5 幢 3、4 层 电话（传真）：0871-63172192 邮编:650032 北京德恒（昆明）律师事务所 关于云南白药集团股份有限公司 2024 年度股东大会的 根据公司提供的有关资料及公开披露的信息，表明公司董事会已于 2025 年 3 月 31 日召开了会议，作出了关于召开本次股东大会的决议，并于 2025 年 3 月 31 日在《中国证券报》《证券时报》《上海证券报》和巨潮资讯网站等媒体刊登 了召开本次股东大会的通知。 本次股东大会于 2025 年 4 月 21 日 9:30 在昆明市呈贡区云南白药街 3686 号 云南白药集团股份有限公司白药空间二楼会议室召开，会议召开时间与通知公告 时间间隔 20 天以上，会议召开的具体时间、地点和审议事项也与公告内容一致。 本次股东大会由公司董事长张文学主持，符合法律、法规及《公司章程》的 规定。 二、关于出席本次股东 ...

Group 1: Overall Financial Performance - In 2024, the company achieved a revenue of 40.033 billion CNY, a year-on-year increase of 2.36% [2] - The net profit attributable to shareholders reached 4.749 billion CNY, up 16.02% from 4.094 billion CNY in the previous year [2] - The non-recurring net profit was 4.523 billion CNY, reflecting a 20.18% increase compared to 3.764 billion CNY last year, marking a historical high [2] Group 2: Growth Quality Indicators - Operating cash flow net amount was 4.297 billion CNY, a growth of 22.68% year-on-year [3] - The weighted average return on equity was 11.99%, an increase of 1.48 percentage points from the previous year [3] - Basic earnings per share were 2.66 CNY, representing a 16.16% increase compared to the previous year [3] Group 3: Cost Management and Efficiency - Sales expenses decreased by 2.26% year-on-year, while management expenses dropped by 1.98% [3] - The industrial revenue accounted for 36.14% of total revenue, with an industrial revenue growth rate of 5.30% [3] - The industrial gross profit margin was 65.93%, an increase of 1.69 percentage points from the previous year [3] Group 4: Asset Structure - As of the end of the reporting period, total assets were 52.914 billion CNY, with net assets attributable to shareholders at 38.832 billion CNY [4] - The debt-to-asset ratio stood at 26.55%, with cash and cash equivalents amounting to 10.888 billion CNY [4] Group 5: Pharmaceutical Business Growth - The pharmaceutical segment focused on becoming the "first brand" in pain management, enhancing product visibility and ecosystem [5] - Clinical research on core products showed steady progress, expanding application scenarios [5] - Marketing initiatives successfully targeted younger demographics, leading to increased product penetration [5] Group 6: Raw Material Cost Control - The Chinese medicine resource segment managed to keep raw material price increases below the industry average [6] - A "big procurement" integrated management platform led to a cost reduction of 31 million CNY [6] - The establishment of a digital ecosystem for traditional Chinese medicine improved supply chain efficiency [6] Group 7: Nuclear Medicine Development - The INR101 diagnostic nuclear medicine project received clinical approval in May 2024, with promising stability and safety results [7] - The INR102 injection for treating advanced prostate cancer has received approval for clinical trials [7]

云南白药集团股份有限公司 投资者调研会议记录表 | 投资者关系活动类别 | □特定对象调研 | | □分析师会议 | | --- | --- | --- | --- | | | □媒体采访 | | □业绩说明会 | | | □新闻发布会 | | □路演活动 | | | □现场参观 | | □一对一沟通 | | | ☑ 其他（电话会议） | | | | 参与单位名称及人员 | 大家资产-胡筱、吴斌 | | | | 姓名 | 长盛基金-李雨辰、洪靖怡 | | | | | 国联证券-陈翠琼 | | | | 时间 | 2025 年 4 17 日星期四 | 月 | | | 地点 | 集团总部办公大楼 | | | | 上市公司接待人员 | 证券事务代表-李孟珏，投资者关系管理-杨可欣 | | | | 投资者关系活动主要 | 了解公司生产经营情况等相关问题 | | | | 内容介绍 | | | | | 附件清单 | 会议记录 | | | 1 / 1 编号：19-2504-14 ...

云南白药集团股份有限公司 投资者调研会议记录 时间：2025 年 4 月 16 日 地点：集团总部办公大楼 答：药品事业群2024年主营业务收入69.24亿元，同比增长11.8%， 单品销售过亿产品达 10 个。核心系列产品中，云南白药气雾剂销售 收入突破 21 亿元，同比增长超 26%；云南白药膏、云南白药胶囊、 云南白药创可贴、云南白药（散剂）均在上年销售收入基础上，实现 显著增长。其他品牌中药类产品增长亮眼，蒲地蓝消炎片销售收入近 2 亿元，同比大幅增长超 22%，血塞通胶囊、小儿宝泰康颗粒、参苓 健脾胃颗粒产品收入均破亿。植物补益类产品，气血康口服液销售收 入继续保持增长态势，同口径下同比增长约 14%。 2、请问公司牙膏产品销售情况如何？未来在渠道布局上有何规 划？ 答：健康品事业群实现营业收入 65.26 亿元，同比增长 1.6%； 实现利润 21.91 亿元，同比增长 8.36%。口腔护理领域，2024 年云南 白药牙膏稳居国内全渠道市场份额第一（数据来源：尼尔森零售研究 数据 IQ202412）；"618""双十一"期间，云南白药口腔健康品牌 多年稳居全网口腔护理品牌第一名（数据来源：商指针） ...

云南白药集团股份有限公司 投资者调研会议记录表 编号：18-2504-13 | 投资者关系活动类别 | □特定对象调研 | | --- | --- | | | □分析师会议 □媒体采访 □业绩说明会 | | | □新闻发布会 □路演活动 | | | □现场参观 □一对一沟通 | | | ☑ 其他（电话会议） | | 参与单位名称及人员 | 中邮基金-梁筱雨 | | 姓名 | 东吴证券-李倩 | | 时间 | 2025 年 4 月 16 日星期三 | | 地点 | 集团总部办公大楼 | | 上市公司接待人员 | 证券事务代表-李孟珏，投资者关系管理-杨可欣 | | 投资者关系活动主要 | 了解公司生产经营情况等相关问题 | | 内容介绍 | | | 附件清单 | 会议记录 | 1 / 1 ...

Investment Rating - The report maintains an "Outperform" rating for the pharmaceutical sector [1]. Core Insights - The commercialization of nuclear medicine is accelerating, with significant growth in diagnostic nuclear drugs and the potential for domestic nuclear drugs to reach a commercialization inflection point [3][17]. - The report highlights the successful commercialization of Pluvicto and Lutathera, which are expected to generate substantial revenues, with Pluvicto projected to exceed $5 billion in peak sales [3][12]. - The report emphasizes the similarities between Radioligand Therapy (RDC) and Antibody-Drug Conjugates (ADC), suggesting that RDC could replicate the success of ADC in the market [3][22]. Summary by Sections Part 1: Overseas Nuclear Drug Rapid Growth, Domestic Commercialization Period - Overseas nuclear drugs are experiencing rapid commercialization, with Pluvicto achieving $1.392 billion in revenue in 2024, a 42% increase, and Lutathera generating $724 million, a 20% increase [3][12]. - The combined revenue from these two drugs for Novartis reached $2.116 billion, indicating the ongoing value realization of nuclear drugs [3][12]. - The report notes that the domestic nuclear drug market is set to expand significantly, with five new nuclear drugs approved since 2020, including Yttrium-90 microspheres from Yuan Da Pharmaceutical, which is expected to generate nearly HKD 500 million in revenue in 2024, a growth rate exceeding 140% [3][20]. Part 2: RDC Expected to Replicate ADC Success Path - RDC shares structural and mechanistic similarities with ADC, consisting of a targeting ligand, a linker, and a radioactive nuclide [3][22]. - The report outlines that both RDC and ADC have followed similar validation timelines, with ADC gaining market traction after the success of Enhertu, while RDC is now gaining attention following the success of Pluvicto [3][22]. - The market for new nuclear drugs is projected to reach approximately $4-5 billion in 2024, comparable to the ADC market size around 2021 [3][22]. Part 3: Domestic Nuclear Drug Pipeline Overview - The report details the current pipeline of domestic nuclear drugs, with three products in the NDA stage, including Novartis's PSMA diagnostic and therapeutic drugs [3][49]. - The leading targets in domestic research remain PSMA, FAP, and SSTR, with companies like Yuan Da Pharmaceutical and Xiantong Pharmaceutical leading in clinical project numbers [3][53]. - The anticipated approval of Novartis's two PSMA-targeted products in Q2 2025 is expected to further stimulate the domestic nuclear medicine market [3][20].

云南白药集团股份有限公司 投资者调研会议记录 时间：2025 年 4 月 14 日 地点：集团总部办公大楼 召开方式：现场调研 投资者：中信里昂-Matthew Yan、David Dong、Charlotte Zhan、 1、药品事业群 2024 年取得较好增长的原因是什么？ 答：2024 年，药品事业群以"伤科疼痛全领域管理的'第一' 品牌"为战略指引，结合产品和品牌禀赋，发布伤痛管理新模式，深 挖白药核心产品在伤科疼痛领域的药效机制，通过"白药+痛舒+伤痛" 相关产品在学术临床方面的深度挖潜，持续打造和提升白药核心产品 在骨伤科、疼痛管理领域的知名度和领先优势，形成大的产品生态体 系。同时，药品事业群进一步优化"品质好中药"运营平台，深入聚 焦心脑血管、呼吸系统、妇儿科等高潜赛道，持续丰富产品管线，打 造药品产业大生态。报告期内，药品事业群从学术临床、市场营销、 渠道细分、生产提效等方面持续推进各项重点工作。学术临床方面， 云南白药（散剂）、胶囊在糖尿病足、骨骼疼痛等方面的临床研究， 宫血宁胶囊在治疗异常子宫出血、减少药物流产后阴道流血等方面的 临床研究，气血康口服液改善心脏和血管健康及对高原反应的预防 ...

Group 1: Investor Relations Activity - The meeting was categorized as a telephone conference [2] - Participants included representatives from Renbao Pension and Dongwu Securities [2] - The meeting took place on April 11, 2025, at the company's headquarters [2] Group 2: Purpose of the Meeting - The main objective was to understand the company's production and operational status [2] - Discussions included various related questions regarding the company's performance [2] Group 3: Attendees - Company representatives included Li Mengjue (Securities Affairs Representative), Zhang Yu, and Yang Kexin (Investor Relations Management) [2] - Investors present were Zhou Yijing and Mao Yating from Renbao Pension, and Li Qian from Dongwu Securities [2]

云南白药集团股份有限公司 地点：集团总部办公大楼 召开方式：电话调研 投资者：人保养老-周依静、毛雅婷，东吴证券-李倩 参加人员：证券事务代表-李孟珏，投资者关系管理-张昱、杨可 欣 会议内容 1、请介绍一下药品事业群 2024 年经营情况 答：药品事业群2024年主营业务收入69.24亿元，同比增长11.8%， 单品销售过亿产品达 10 个。核心系列产品中，云南白药气雾剂销售 收入突破 21 亿元，同比增长超 26%；云南白药膏、云南白药胶囊、 云南白药创可贴、云南白药（散剂）均在上年销售收入基础上，实现 显著增长。其他品牌中药类产品增长亮眼，蒲地蓝消炎片销售收入近 2 亿元，同比大幅增长超 22%，血塞通胶囊、小儿宝泰康颗粒、参苓 健脾胃颗粒产品收入均破亿。植物补益类产品，气血康口服液销售收 入继续保持增长态势，同口径下同比增长约 14%。 2、省医药公司主要做了哪些工作？ 投资者调研会议记录 时间：2025 年 4 月 11 日 答：省医药公司积极应对国家药品集中带量采购、医保控费及公 立医院国考等重大医改政策变化，持续提升医药供应链运营能力和客 户服务能力，探索与实践新时代下医药供应链的价值创造。通过 ...

Group 1: Investor Relations Activity - The meeting was categorized as a specific object survey [2] - Participants included representatives from Citic Securities and Sumitomo Mitsui Asset Management [2] - The meeting took place on April 14, 2025, at the company's headquarters [2] Group 2: Purpose of the Meeting - The main objective was to understand the company's production and operational status [2] - The meeting involved direct communication with investor relations representatives [2]