Group 1: New Energy Business - The company primarily focuses on the sales of LiFSI, cathode materials, and electrolyte products, with ongoing technical improvements on lithium hexafluorophosphate projects. Revenue from the new energy business is expected to break through in 2025, with further growth anticipated in 2026 [1] - The company aims to expand its product range and market presence in the new energy sector, leveraging its R&D and production capabilities to convert technological advantages into market benefits [1] - The new energy sector is viewed as a sufficiently broad and long-term opportunity, helping to mitigate operational risks associated with the company's previous focus on overseas CDMO clients [2] Group 2: Overseas Operations - The UK base has maintained stable production and operations in 2025, with expectations for continued stability in 2026. The Malaysian base plans to invest $200 million, with the first phase of construction ongoing and expected to complete by the end of 2026 [3] - The Malaysian facility will focus on producing agricultural CDMO products, with plans to gradually commence production based on customer orders starting in 2027 [3] Group 3: Pharmaceutical Business - The pharmaceutical segment has shown steady growth, with a focus on a large client strategy and CDMO business model. The company has established stable commercial relationships with several leading global pharmaceutical companies [4] - The company is actively expanding its client base and developing new strategic partnerships, particularly with high-viscosity clients, while also focusing on small molecule CDMO and emerging business areas such as peptide products and radiopharmaceuticals [4] Group 4: Client Dependency and Market Strategy - The company acknowledges a high concentration of clients but emphasizes the importance of providing comprehensive services to existing clients while actively seeking new customers across various sectors [4] - The strategy includes enhancing technical capabilities and market expansion to foster long-term cooperation and mutual trust with clients, ensuring a sustainable business model [4]

Group 1: Small Nucleic Acid Business - The company’s small nucleic acid business primarily involves phosphoramidite monomers and GalNAc delivery systems, with delivery systems priced higher than monomers [2] - The company has delivered part of its small nucleic acid business orders and will continue to meet customer needs, with further details available in future reports [2] - The company possesses a stable and effective quality system, necessary production equipment and technology, smooth supply chain responsiveness, and compliance advantages to become a supplier for multinational corporations (MNCs) [2][3] Group 2: Production Capacity and Main Business - The company’s fundraising projects are gradually releasing production capacity to meet diverse customer orders [3] - The main business includes providing key pharmaceutical intermediates, active pharmaceutical ingredients (APIs), CDMO services, L-carnitine series products, and stem cell drug development [3] - The company is focused on continuous innovation in new products and processes to expand product depth and breadth, aiming for a richer customer structure [3] Group 3: Stem Cell Project Progress - The company has completed the design, installation, debugging, and confirmation of GMP facilities for its cell therapy projects, including myocardial infarction and cerebral infarction [3] - Technical transfers for the isolation, culture, and cryopreservation of umbilical cord mesenchymal stem cells have been completed, establishing seed, master, and working cell banks [3] - The company has developed and validated analytical methods and initiated process validation in preparation for IND application [3] Group 4: Disclosure of Major Information - The activity did not involve the disclosure of any undisclosed major information [3]

Key Points Summary of 九州药业 Conference Call Company Overview - 九州药业 is transitioning from generic drugs to innovative drug services, established in 1973 and entered the pharmaceutical sector in 1985. The company began its CDMO (Contract Development and Manufacturing Organization) business in 2008 and went public in 2014 [3][4]. Industry and Business Structure - The company has achieved synergy in domestic and international production through acquisitions and self-built capabilities, including the establishment of an overseas management headquarters in Singapore and R&D platforms in Japan and Germany [2][3]. - The core revenue source is the CDMO business, which generated revenue of 22.91 billion yuan in the first half of 2025, representing a year-on-year growth of 16.27% with a gross margin of 41% [2][3]. Project Pipeline and Clientele - The project pipeline has increased from 378 in 2019 to 1,214 as of the first half of 2025, including 38 commercialized products [2][3]. - Major clients include multinational corporations (MNCs) such as Novartis, Roche, and Pfizer, with Novartis accounting for over 60% of the revenue [2][5]. Financial Performance - In the first half of 2025, the raw material drug business generated revenue of 5.23 billion yuan, maintaining a gross margin of 23% despite industry competition and price declines [2][5]. - The company expects a net profit growth of around 15% over the next three years, with a revenue increase of 4.92% and a net profit increase of 18.51% year-on-year in the first three quarters of the current year [4][5]. New Business Initiatives - The establishment of the Prince Division aims to develop new molecular types such as peptides, conjugated drugs, and small nucleic acids, creating a second growth curve [2][5]. - The company is advancing commercial production capacity for these new initiatives, including three peptide conjugation platforms and capabilities for small nucleic acid research in both China and the U.S. [5]. Market Outlook and Valuation - The company is projected to maintain a net profit growth rate of approximately 15% over the next three years, with a target price of 27 yuan based on a 21x P/E ratio for 2026 [4][5]. - The current stock price reflects a P/E ratio of about 12x for 2027, indicating a favorable investment opportunity considering the rebound in raw material prices and healthy development in small molecule CDMO [5].

Core Viewpoint - Jiuzhou Pharmaceutical is entering a growth phase driven by its CDMO platform, which leverages its expertise in small molecules and TIDES, supported by a healthy project pipeline and high order visibility [3][5]. CDMO Business - The CDMO business is the main growth engine, with a robust project funnel and high order visibility. The company provides comprehensive lifecycle services from preclinical CMC to commercial production, deeply embedded in the supply chains of major pharmaceutical companies like Novartis and Roche [3]. - Key projects such as Noxafil and Ribociclib continue to generate revenue, while the rapid growth of the partnered product Vumerity is expected to provide sustained incremental growth [3]. - As of H1 2025, the company has a rich pipeline with 38 products on the market, 90 in Phase III, and 1,086 in Phase I/II, driving steady revenue growth [3]. API Business - The company focuses on specialty APIs, optimizing processes to enhance cost advantages. It holds a strong position in the CNS and anti-infection specialty API markets [4]. - Core product prices are expected to improve as industry inventory depletion nears completion, while new product categories are being introduced, including four specialty APIs by 2025 [4]. - Continuous process optimization and reduced development cycles are helping to maintain cost advantages, with an API business gross margin of 23.26% in H1 2025, up 2.08 percentage points year-on-year [4]. Formulations and CDMO - The company has made significant strides in its formulation and CDMO business through acquisitions and the establishment of its own facilities, completing its layout for generic and innovative drug formulations [4]. - As of Q3 2025, the formulation pipeline includes 22 projects, with 8 approved and 9 submitted for approval. The CDMO business has onboarded over 10 high-quality domestic and international clients, adding more than 30 new service projects [4]. - The formulation business is expected to maintain rapid growth in the future [4]. Investment Recommendation - The company has established a one-stop CDMO platform covering small molecules, peptides, conjugates, and formulations, serving major global pharmaceutical companies and achieving localized R&D in the US, Japan, and Germany [5]. - Projected net profits for 2025-2027 are estimated at 966 million, 1.128 billion, and 1.303 billion yuan, representing year-on-year growth of 59.4%, 16.8%, and 15.4% respectively [5]. - The current stock price corresponds to PE ratios of 16, 14, and 12 for 2025-2027. Given the company's growth prospects and strong order visibility, a target price of 26.64 yuan is set, with an initial "recommend" rating [5].

Group 1: New Energy Business - The company has decided to enter the new energy sector, focusing on chemical synthesis capabilities, which are deemed competitive for commercialization [1] - Expected revenue from the new energy business is projected to break through in 2025, primarily driven by sales of LiFSI and electrolyte products [1] Group 2: Pharmaceutical Business - The pharmaceutical segment is growing rapidly, with a focus on a CDMO business model and partnerships with leading global pharmaceutical companies [1] - The company aims to expand its client base and enhance its product pipeline, anticipating long-term growth as it deepens collaborations with clients [2] Group 3: Malaysia Base Construction - The establishment of a base in Malaysia is intended to meet client supply chain diversification needs and enhance customer loyalty [2] - The Malaysian facility is currently in the construction phase, with production expected to commence within the year [2] Group 4: Crop Protection Business - The crop protection business remains stable, with the company recognized as a strategic partner for major global original research crop protection companies [2] - The company provides comprehensive solutions covering the entire product lifecycle in the crop protection sector [2] Group 5: Capital Expenditure Considerations - Current capital expenditures are focused on the coastal base and the Malaysian facility, with a net cash flow from operating activities of approximately 9 billion yuan in the first three quarters of 2025 [2] - There are no immediate plans for capital operations as the current cash flow supports ongoing capital expenditure plans [2] Group 6: Subsidiary Shanghai Baofeng - Shanghai Baofeng has been listed on the New Third Board and aims to improve product and service quality while expanding into international markets [2] - The subsidiary is focused on maintaining stable growth in traditional refrigeration sectors [2]

Core Viewpoint - The control of Jiuzhou Pharmaceutical has changed due to the transfer of shares from the aging actual controller, Hua Xuande, to his daughters, Hua Lirong and Hua Xiaohui, which will not affect the company's operational independence or business performance [2][4]. Group 1: Share Transfer Details - Hua Xuande transferred 42.50% of his shares in Zhongbei Group and 10.00% in Taizhou Gede to his daughters, with Hua Lirong receiving 28.50% and Hua Xiaohui 14% of Zhongbei Group, and each receiving 5% of Taizhou Gede [1]. - The total payment for the share transfer was 61.815 million yuan, with Hua Lirong paying 41.333 million yuan and Hua Xiaohui 20.482 million yuan [1]. - The estimated market value of the shares transferred, based on Jiuzhou Pharmaceutical's closing price of 19.88 yuan per share, is approximately 2.476 billion yuan [1]. Group 2: Company Background and Performance - Jiuzhou Pharmaceutical, established in July 1998, is a technology-driven CDMO enterprise focusing on small molecule chemical drugs, peptide drugs, conjugated drugs, and small nucleic acid drugs [4]. - The company reported a revenue of 4.16 billion yuan for the first three quarters of the year, representing a year-on-year growth of 4.92%, and a net profit of 748 million yuan, up 18.51% year-on-year [4]. - As of November 13, Jiuzhou Pharmaceutical's stock price increased by 2.11% to 20.34 yuan per share, with a market capitalization of 18.091 billion yuan [5].

Investment Rating - The report maintains a "Buy" rating for the company [5]. Core Views - The company reported a revenue of 46.30 billion yuan for the first three quarters of 2025, representing a year-on-year growth of 11.82%, with a net profit attributable to shareholders of 8.00 billion yuan, up 12.66% year-on-year [1]. - In Q3 2025, the company achieved a revenue of 14.4 billion yuan, a slight decline of 0.09% year-on-year, with the small molecule business revenue declining over 20% year-on-year, while emerging businesses saw a significant growth of 114% year-on-year [2]. - The company expects a revenue growth of 13% to 15% for the full year 2025, translating to an estimated revenue of 65.6 to 66.8 billion yuan, with Q4 revenue projected to be between 19.3 and 20.5 billion yuan, indicating a year-on-year growth of 15.9% to 22.9% [2]. Summary by Sections Financial Performance - For Q1-Q3 2025, the company achieved a revenue of 46.30 billion yuan and a net profit of 8.00 billion yuan, with a non-GAAP net profit of 7.28 billion yuan [1]. - The company’s Q3 revenue was 14.4 billion yuan, with a decline in small molecule business revenue but a doubling in emerging business revenue [2]. Future Outlook - The company is focused on expanding its market presence, with new orders showing double-digit growth, which adds certainty to future performance [2]. - The company anticipates a significant increase in Q4 deliveries compared to Q3, supporting the revenue growth guidance for 2025 [2]. Investment Recommendations - The company is positioned as a leading domestic small molecule CDMO supplier, with ongoing enhancements in its integrated service capabilities in small molecules and continued investment in large and biological molecules [3]. - Adjusted revenue forecasts for 2025-2027 are 66.09 billion, 77.48 billion, and 89.30 billion yuan, respectively, with EPS estimates revised to 3.05, 3.66, and 4.50 yuan [3].

Investment Rating - The report maintains a "Buy" rating for the company, indicating an expected investment return that will outperform the market benchmark by over 20% in the next 6-12 months [5][11]. Core Insights - The company achieved a revenue of 4.47 billion yuan in the first three quarters of 2025, representing a year-on-year growth of 1.2%, while the net profit attributable to the parent company reached 670 million yuan, up 15.8% [1][5]. - The gross margin improved to 26.9%, an increase of 0.7 percentage points, and the net margin rose to 14.9%, up 1.8 percentage points [1][5]. - The decline in revenue for Q3 was primarily due to weak demand for antibiotics and the traditional off-season for raw materials, but profitability continued to improve with rising margins [1][2]. - The company has a diverse product matrix with over 70 chemical drug products, 13 of which generate over 100 million yuan in revenue, and nearly 20 products hold leading market shares [2]. Financial Projections - Revenue forecasts for 2025-2027 are 6.41 billion yuan, 7.29 billion yuan, and 8.17 billion yuan, reflecting year-on-year growth rates of 8.8%, 13.6%, and 12.2% respectively [3][10]. - The net profit projections for the same period are 943 million yuan, 1.16 billion yuan, and 1.38 billion yuan, with growth rates of 20.6%, 23.2%, and 18.5% respectively [3][10]. - The report highlights a continuous improvement in profitability driven by the company's market share in animal health products and cost efficiencies [3][10].

Core Viewpoint - Goldman Sachs has slightly reduced its net profit forecasts for Kanglong Chemical (300759) for the years 2025 to 2027 by 0.1%, 0.1%, and 0.5% respectively, while maintaining a "Buy" rating for its H-shares and a neutral rating for its A-shares [1] Group 1: Financial Performance - Kanglong Chemical reported third-quarter revenue of 3.65 billion RMB, representing a year-on-year growth of 13.4% and a quarter-on-quarter increase of 9.1%, slightly above Goldman Sachs' previous expectation of 3.48 billion RMB [1] - The growth in revenue was primarily driven by sustained momentum in the CMC and bioscience sectors, with contributions from the top twenty pharmaceutical clients increasing [1] - The non-IFRS adjusted net profit margin improved to 12.9%, compared to 11.3% in the first quarter and 12.2% in the second quarter, benefiting from increased utilization and operational leverage [1] Group 2: Management Guidance - The management of Kanglong Chemical has raised its full-year revenue growth guidance from 10%-15% year-on-year to 12%-16%, indicating a fourth-quarter growth of 6%-20% [2] - It is expected that the profit margin in the fourth quarter will further improve compared to the first three quarters, although the overall non-IFRS profit margin for the year may be slightly lower than in 2024 due to profit margin dilution from new capacity released in the first quarter [2] - Management remains confident in achieving the revised guidance, citing strong growth in CMC orders, ongoing capacity expansion, and improvements in core business profit margins [2]

Core Viewpoint - The A-share market is experiencing a collective decline, with major indices such as the Shanghai Composite Index down by 0.75%, the Shenzhen Component Index down by 0.76%, and the ChiNext Index down by 1.68% [1] Group 1: Market Performance - The Kexin Pharmaceutical ETF (588130) has increased by 4.28%, with the latest price at 1.195 yuan and a turnover rate of 13.94% [1] - Among the constituent stocks, three companies led the gains: 3SBio surged by 20.00%, Zai Lab (U.S.) rose by 15.50%, and EdiGene (U.S.) increased by 14.08% [1] - Conversely, Haoyuan Pharmaceutical led the losses with a decline of 4.80%, followed by Yirui Technology down by 1.59%, and Baijun Medical down by 1.14% [1] Group 2: Investment Recommendations - Guosen Securities suggests focusing on innovative drug companies with differentiated capabilities and global commercialization potential, as well as leading CDMO companies with high growth in new contracts and backlog orders [1] - The long-term logic of innovative drugs is viewed positively, with an emphasis on identifying bottom-reversal targets [1] - There is a recommendation for low-valuation medical device companies that are expected to experience performance turning points or acceleration [1]