在优化要素保障环境上，合肥市将积极探索开展生物制品分段生产试点，在确保质量可控的前提下，提 升企业生产灵活性和资源配置效率。加强与海南自贸港联动，深化与博鳌乐城国际医疗旅游先行区对接 合作，承接并转化试点成果。加快推进规划环评与项目环评联动机制，简化审批流程，为企业减负增 效。 在提升服务响应速度上，合肥市将全力支持市药品审评核查分中心建设，提升审评核查速度，做到"早 介入、快响应、强服务"，加速产品上市进度。依托安徽省、上海市医疗资源支持，建设合肥市医疗器 械检验检测中心，提升本地医疗器械检测能力。进一步完善经开区、高新区两个省级医药创新柔性服务 站功能，为企业提供零距离、个性化的前置指导服务。 在打通临床转化路径上，合肥市将加快建设中国科学院临床研究医院，推动研究型病房建设，支持研究 者发起的临床研究和真实世界研究，提升多中心临床试验伦理审查效率。创新"新质药械"产品进院模 式，打造药械应用场景示范医疗机构，畅通优质药械推广渠道。推动中国科学院合肥肿瘤医院与瑞金医 院海南医院深度合作，支持港澳台地区医生在自贸试验区内短期执业，依托省国际医疗联盟，推进国际 医疗服务标准化、同质化发展。 合肥市副市长王海霞透 ...

Core Viewpoint - Hangzhou is committed to accelerating the construction of a global advanced manufacturing base by integrating technological and industrial innovation, aiming for high-quality economic development by 2025 [1] Group 1: Advanced Manufacturing Cluster - Hangzhou is advancing the "296X" advanced manufacturing cluster initiative, which includes two trillion-level industry clusters in artificial intelligence and visual intelligence, and nine hundred billion-level clusters in various sectors [2] - The city's industrial added value is projected to reach 462.4 billion yuan in 2025, marking a 6% increase from the previous year, the fastest growth in four years [2] Group 2: High-Quality Development Foundation - Hangzhou has maintained the highest manufacturing quality development index in Zhejiang province for six consecutive years and is set to receive the "Golden Ding" award in 2025 [3] Group 3: Innovative Ecosystem - The city is fostering a robust innovation ecosystem, with new enterprises like the "Six Little Dragons of Hangzhou" gaining prominence and significant technological advancements in humanoid robots and AI models [4] - By the end of 2025, Hangzhou will have established several key platforms for AI medical applications and innovative drug approvals, achieving a historical high [4] Group 4: Digital Economy - The core digital economy industries in Hangzhou are expected to generate an added value of 678 billion yuan in 2025, with a growth rate of 9.3%, accounting for 29.5% of the GDP [6] - The revenue from the software and information technology services sector is projected to reach 1,301.147 billion yuan, with a growth rate of 14% [6] Group 5: International Cooperation - Hangzhou is enhancing its role in international cooperation within the industrial economy, with the establishment of the China-Africa Digital Technology Cooperation Center and the International Silk Organization [7] Group 6: National Pilot Projects - The city is leading national pilot projects, including the largest smart connected vehicle testing area in the country, covering 6,910 square kilometers [9] Group 7: Policy Initiatives - In 2025, Hangzhou will introduce a series of policies to promote high-quality manufacturing development, including a three-year action plan and specific measures for various industries [10] Group 8: Quality Enterprise Cultivation - The city aims to accelerate the cultivation of quality enterprises, with six new national manufacturing champions and 129 new specialized "little giant" enterprises added in 2025 [11] Group 9: Support for Enterprises - Hangzhou is facilitating industrial circulation through targeted services, with 232 matchmaking events held, resulting in order amounts of 3.87 billion yuan and financing connections of 11.99 billion yuan [12]

隔夜美股大跌，金银价格重挫，中概指数跌3%。港股蛇年最后一个交易日，三大指数大幅低开，恒指 跌1.45%，国指跌1.23%，恒生科技指数跌1.59%。权重科技股集体下挫，百度跌3.6%，阿里巴巴跌 2.9%，腾讯、京东皆有跌幅；黄金和白银突遭抛售，黄金股带领有色金属股齐跌，汽车股、银行股、 生物医药普跌。另外，"AI除幻第一股"海致科技集团港股上市首日高开204%，带领部分AI应用概念股 上涨。(格隆汇) ...

Major Events - Fuhong Hanlin (02696) received NMPA approval for the Phase I clinical trial application of HLX15-SC for the treatment of multiple myeloma [1] - Kangzheng Pharmaceutical (00867) signed an exclusive distribution agreement for the original drug Lidoderm® lidocaine gel patch [1] - MicroPort Robotics-B (02252) surpassed 200 global commercial orders for the Tumai® laparoscopic surgical robot [1] - BGO Group (08220) plans to acquire a proposal from Stephen Chow at a discount of approximately 91.79% [1] - Kogee Pharmaceuticals-B (02171) signed a strategic cooperation agreement with Shanghai Jinguang Enterprise Development to build a commercial production base for CAR-T cell therapy products in Jinshan [1] Operating Performance - China Resources Land (01109) reported total contract sales of approximately 11.65 billion yuan in January, a year-on-year increase of 0.4% [1] - Hua Hong Semiconductor (01347) announced a profit attributable to the parent company of 54.881 million USD for 2025, a year-on-year decrease of 5.6% [1] - China Coal Energy (01898) reported coal sales of 20.05 million tons in January, a year-on-year decrease of 7.3% [1] - China Metallurgical Group (01618) signed new contracts worth 73.65 billion yuan in January [1] - China Communications Construction (01800) reported new contracts worth 1.883672 trillion yuan for 2025, a year-on-year increase of 0.13% [1]

Investment Rating - The industry rating is neutral, indicating that the overall return is expected to be between -5% and 5% relative to the CSI 300 index over the next six months [9]. Core Insights - Eli Lilly's new drug, Migalastat, has received approval from the National Medical Products Administration (NMPA) in China for the treatment of moderate to severe active Crohn's disease (CD) and ulcerative colitis (UC) in adults. This drug selectively inhibits the IL-23 pathway, which is involved in immune inflammatory responses [5]. - The pharmaceutical sector experienced a slight decline of -0.32% on February 11, 2025, underperforming the CSI 300 index by 0.10 percentage points, ranking 22nd among 31 sub-industries [4]. - Notable stock performances included Teva Biopharmaceuticals (+6.01%), ZhenDe Medical (+5.87%), and Keyuan Pharmaceutical (+5.79%) on the gainers' list, while Huakang Clean (-5.28%), Hualan Biologicals (-5.11%), and Qianyuan Pharmaceutical (-4.67%) led the decliners [4]. Sub-industry Summary - Chemical Pharmaceuticals: No rating [3] - Traditional Chinese Medicine: No rating [3] - Biopharmaceuticals II: Neutral [3] - Other Pharmaceutical Industries: Neutral [3]

格隆汇2月13日丨科济药业-B(02171.HK)发布公告，2026年2月12日，科济药业控股有限公司透过其间接 全资附属公司上海恺兴诊断技术，与上海市金山区湾区高新区的重要平台企业——上海金工企业发展签 署战略合作协议，总投资额不超过人民币3.7亿元，将在上海市金山区建设先进的CAR-T细胞治疗产品 商业化生产基地。 此举紧密配合公司多款CAR-T细胞治疗产品的商业化进程，包括已上市的赛恺泽®及处于新药上市申请 阶段的实体瘤CAR-T细胞治疗产品舒瑞基奥仑赛注射液(拟定商品名：恺力美TM)，并为多款通用型 CAR-T细胞治疗产品(如CT0596、CT1190B等)的未来量产奠定基础。在此背景下，提升符合国际标准的 CAR-T细胞治疗产能成为支撑多个产品商业化落地及增强全球竞争力的核心举措。此次交易公司早期无 需进行大额资本开支，有效保留了宝贵现金流用于核心研发与市场拓展。同时，回购机制确保本公司在 长期运营后可完整取得资产控制权，既维持了生产稳定性，又强化了资产布局的灵活性。 总体来看，此次合作彰显了公司稳健的财务规划和对CAR-T细胞治疗产业生态系统的深度布局，也表明 该项目高度契合国家及地方的生物医药产 ...

转自：北京青年报 实现119个"高效办成一件事"、免罚慎罚事项达1000余项、3088个政务服务事项实现统一申办受理…… 北京青年报记者昨日从北京市发改委获悉，《北京市营商环境发展报告2025："北京服务"推动首都高质 量发展》（北京营商环境"白皮书"）已正式发布。"白皮书"进一步聚焦"北京服务"品牌建设最新成果和 对推动高质量发展的有力支撑，用量化数据和典型案例回应企业高频关切领域，帮助各类经营主体更清 晰地了解北京的政策环境，进一步坚定在京投资兴业的信心、把握在京发展机遇。 全年新设经营主体38.01万户 "经济稳健增长，为企业筑牢发展根基。"市发改委相关负责人介绍，企业在京发展宏观环境不断优化， 2025年，北京地区生产总值突破5万亿元，人均地区生产总值与全员劳动生产率稳居全国领先水平。 过去一年，企业全周期服务体系提质升级。本市推动政务服务标准体系完善和数字化转型，"京策"平台 汇聚2025年新发布政策1805份，上线政策兑现事项1112个。 创新推出政策服务、数字服务、热线服务"三送"服务，向213万家企业推送政策兑现事项。12345企业服 务热线受理企业诉求57.83万件，同比增加127%。"本市 ...

本报评论员 新征程是充满光荣和梦想的远征，没有捷径，唯有实干。让我们更加自觉地站在党和国家事业发展全局 的高度来想问题、作决策、办事情，为扎实推动高质量发展，更好服务党和国家工作大局作出新的贡 献。 当前正值"十五五"开局起步，北京率先基本实现社会主义现代化进入关键期，总书记站在党和国家事业 发展全局的高度，进一步深刻阐释了"建设什么样的首都、怎样建设首都"这一重大时代课题，要求北京 深入贯彻党的二十届四中全会精神，落实党中央确定的城市战略定位，精准务实推动经济社会发展，确 保率先基本实现社会主义现代化取得决定性进展，努力在全国发挥示范作用。总书记从京津冀协同发 展、构建高精尖经济结构、促进城乡融合发展、深化改革开放等方面，提出了一系列新的重大论断和明 确要求。我们要结合总书记历次对北京重要讲话和指示批示精神，结合各自岗位职责和工作实际，学深 悟透、学以致用。 建设社会主义现代化强国，关键在科技自立自强。此次考察中，总书记强调："要充分发挥我们国家集 中力量办大事的优势，把各种优质要素集合起来攻关，加快解决突出短板问题，实现我们的战略目 标。"首善之区，就是攻坚尖兵；资源所在，就是责任所在。北京要充分发挥教育 ...

Group 1 - The market regulatory authority has achieved significant breakthroughs in the development of multi-dimensional detection technology and standard substances for characteristic biomolecules, addressing common international challenges in digital PCR and complex protein quantification [1] - A new method, ES-DMA-CPC, has been developed for the quantification of large molecular proteins up to 300kD without the need for enzymatic or hydrolytic processes, achieving equivalence with isotope dilution mass spectrometry [1] - The research team has created a series of standard substances, including DNA, viral nucleic acids, and monoclonal antibodies, which provide traceability benchmarks for PCR, digital PCR, sequencing, and mass spectrometry detection technologies [1] Group 2 - In the field of proteomics, a multi-level quality control and evaluation system has been established, along with a standard reference dataset that is internationally comparable and traceable [2] - An automated and intelligent model for quality assessment and anomaly detection in proteomics data has been developed, utilizing 10 machine learning algorithms and 170 hyperparameters, establishing a reliable data processing paradigm for large-scale proteomics research [2] - The research team has created the iDIA-QC tool for DIA-MS, marking a significant advancement in quality governance and methodological standardization in large-scale proteomics [2] Group 3 - High-performance AI models such as TSARseqNovo and GraphNet have been developed to achieve full-process automation in spectrum analysis, quality control, and standard comparison, laying the foundation for credible high-throughput omics data measurement [3] - A smart diagnostic system for the malignancy of thyroid nodules has been developed, achieving an accuracy rate of over 90%, utilizing targeted proteomics and AQUA technology for quantifiable and scalable screening of major diseases [3] - The series of original technologies significantly enhances the standardization of proteomics and diagnostics in China, strengthening the core competitiveness of the biopharmaceutical industry and promoting the development of precision medicine and public health emergency capabilities [3]

广东深圳 冲刺"人形机器人第一城" 本报记者程远州 近日，去广东深圳市K11商场看电影的市民惊奇地发现，递上爆米花的居然是一台人形机器人。识别指 令、抓取纸杯、装填爆米花、递给顾客……这台由深圳市越疆科技股份有限公司生产的机器人，单日可 以连续工作14小时，日均完成超1000杯爆米花的制作与售卖，全程零失误。 "最大的难题是'眼、脑、手'协同——机器人既要精准识别环境变化，又要快速决策，还要实现毫米级 的精细操作。"越疆科技创始人兼首席执行官刘培超说，项目启动初期，机器人存在抓取纸杯时用力过 猛捏扁杯身、装填爆米花时撒落等问题，遇到顾客移动杯子、物料撒落等突发情况，更是直接"罢工"。 对于机器人而言，售卖爆米花看似简单实则挑战性极强。越疆科技组建硬件、算法、软件等多部门联合 攻关小组，反复调试机器人指尖压力传感器，让机器人能秒级识别环境变化，反复模拟爆米花撒落、容 器移位等20多种场景，让机器人能自主诊断偏差、重新规划动作，无需人工干预即可续行任务。 钻研技术，换来突破。越疆人形机器人搭载自研的端到端模型，融合视觉感知、语言理解与动作生成， 配合具有高度稳定性和操作精度的硬件，从而在电影院柜台环境中实现了自主 ...