Group 1: Core Employment Strategies - Taiyuan University of Science and Technology has developed an innovative employment service system based on "AI training empowerment, job-seeking study tours, and collaboration between schools, local governments, and enterprises" to enhance the quality and quantity of student employment [1][2] - The university has implemented an "AI Interview Simulation System" that allows students to practice interviews with an AI interviewer, providing insights into their strengths and weaknesses [2][3] - Over 80% of the 2025 graduating class improved their interview skills through the AI training system [2] Group 2: Job-Seeking Activities - The university organized immersive study tours in collaboration with local human resources departments, allowing students to visit companies and understand job requirements firsthand [3][4] - During these study tours, students submitted 35 resumes, resulting in 12 initial employment intentions with companies [3] Group 3: Collaborative Recruitment Efforts - Taiyuan University has established a platform for cooperation between schools, local governments, and enterprises, conducting 27 group recruitment events since fall 2024, attracting 622 quality companies and offering over 13,000 job positions [4][5] - The university has signed talent cooperation agreements with various cities and established talent work liaison stations to enhance recruitment efforts [5]

原标题：AI辅助去核提升犬科动物克隆效率 记者7月14日从青岛农业大学动物科技学院获悉，该院博士赵明辉团队克隆的两只幼犬健康存活， 且已于近日完成疫苗接种和保育流程。它们于今年2月诞生，在其克隆过程中人工智能技术发挥了关键 作用。 赵明辉介绍，团队通过将AI视觉识别技术与显微操作技术融合，成功提取出卵母细胞细胞核位置 的特征信息，并用于机器学习，最终得到能够成功预测犬卵母细胞细胞核位置的人工视觉模型。实验证 实，该模型可在数十毫秒内完成对卵母细胞细胞核位置的预测。 "我们将该模型与虚拟现实技术相结合，把预测的细胞核位置投射到显微镜目镜上，方便操作人员 更精准地进行卵母细胞去核操作。"赵明辉说，这一技术方法大幅降低了操作人员的劳动强度，提高了 犬科动物的克隆效率。 一直以来，犬类克隆被认为是体细胞克隆领域的技术高地。以往，犬类克隆一直依赖犬体内成熟的 卵子，但可用的卵子数量有限，导致犬类体细胞克隆效率低下。此外，犬科动物细胞质中脂肪较多，细 胞质呈黑色，细胞核不可见，导致细胞核去除效率低，进一步限制了克隆犬的生产效率和技术推广。 在此次克隆实践中，研究团队共制备了67枚体细胞核移植胚胎，并分别移植到6只受体犬中 ...

Group 1 - The UK Biobank has completed the largest human imaging project globally, scanning 100,000 volunteers over 11 years, generating over 1 billion high-resolution medical images [1] - The project began in 2014 with a pilot involving 7,000 volunteers and officially launched in 2016, where each volunteer underwent approximately 5 hours of imaging [1] - The imaging data includes over 12,000 MRI images per volunteer, covering the brain, heart, abdomen, and measurements of bone density and body fat [1] Group 2 - Since 2015, the imaging data has been made available to global researchers, resulting in over 1,300 peer-reviewed papers published based on this data [2] - The second phase of the project started in 2022, aiming to re-scan 60,000 participants to observe changes over time, expected to be completed by 2029 [2] - The chief researcher, Rory Collins, emphasized that this unprecedented scale of imaging is making "invisible disease processes" visible and redefining understanding of health, aging, and risk prediction [2]

Group 1 - China is currently the largest producer of chemical and pharmaceutical products globally, accounting for approximately 50% of the global market share, and is a leader in process engineering, chemical engineering, and pharmaceutical engineering [1] - The 12th World Chemical Engineering Congress and the 21st Asia-Pacific Chemical Alliance Conference, held for the first time in China, reflects the international community's high recognition of China's chemical engineering industry [1][2] - The conference theme is "Chemical Engineering Paradigm Shift in Response to Global Challenges," emphasizing the need for the chemical industry to adapt to new demands arising from the energy and green revolutions [2] Group 2 - The conference aims to foster global cooperation, with emphasis on innovation as a core driving force and open international collaboration as a key path to accelerate technological breakthroughs and deep industrial transformation in the chemical sector [2] - The Chinese chemical industry has developed a comprehensive and competitive modern chemical industry system, ranking first in the world in terms of output value, which exceeds 40% of the global total [3] - There is a need for breakthroughs in high-purity chemical manufacturing and testing, which can be supported by cutting-edge technologies such as artificial intelligence [3]

Group 1 - The LIGO-Virgo-KAGRA collaboration announced the capture of a record-breaking black hole merger event named GW231123, involving black holes with masses of 140 and 100 solar masses, resulting in a supermassive black hole of 225 solar masses [1][2] - This discovery challenges existing stellar evolution theories, as such massive black holes were not expected to exist, suggesting that the merging black holes may have formed from earlier smaller black holes [1] - Since the first detection of gravitational waves in 2015, the collaboration has recorded over 300 black hole merger events, with more than 200 detected during the current observational run from May 2023 to January 2024 [1] Group 2 - LIGO's Executive Director, David Reitze, emphasized that this observation provides a unique window into the nature of black holes, with the merging black holes exhibiting remarkable mass and rotation speeds that challenge current detection technologies and theoretical models [2] - The research team acknowledged that fully analyzing the complex signal may take years, and they are improving analysis methods and theoretical models, with calibration data to be made available to global researchers through the Gravitational Wave Open Science Center [2] - The breakthrough discovery will be formally presented at the 24th International Conference on General Relativity and Gravitation in Glasgow, UK, from July 14 to 18, 2025, potentially sparking new discussions on black hole formation mechanisms [2]

Core Insights - Chinese scientists have made significant progress in brain mapping research, with 10 studies published in international journals, including "Cell" and "Neuron," showcasing advancements in understanding brain structure and function [1][2][3] Group 1: Research Achievements - The "Whole Brain Mesoscopic Neural Connectivity Atlas" project aims to create detailed brain maps of non-human primates and humans, addressing the complexity of mammalian brains, which contain nearly 100 billion neurons and over 100 trillion connections [2][3] - A team of over 300 researchers from more than 30 institutions has successfully completed studies that analyze brain cell diversity, connectivity patterns, and molecular mechanisms of brain diseases, enhancing China's international influence in this field [2][3][6] - The research includes the first high-resolution evolutionary atlas of 1.3 million brain cells from various species, revealing key gene evolution related to differences in brain cell types across species [3][12] Group 2: Technological Innovations - The development of specific genetic tools for primate brain research allows for precise delivery of functional proteins to targeted cells, potentially enabling targeted therapies for brain diseases [4][5][25] - A new collection of tools for specific labeling and observation of primate brain cells has been established, marking a significant advancement in understanding brain structure and diseases [4][25][30] Group 3: Collaborative Efforts - The establishment of the "International Primate Mesoscopic Brain Atlas Alliance" aims to enhance global collaboration in brain mapping research, with a focus on creating a shared database for brain atlas data [9][32] - The research integrates contributions from various international institutions, highlighting the collaborative nature of modern neuroscience research [9][32] Group 4: Future Directions - The goal is to complete the mesoscopic neural connectivity atlas for mice by 2025 and for macaques by 2035, indicating a long-term commitment to advancing brain mapping technologies [8][9] - Continued development of imaging and labeling technologies is essential for achieving high-quality brain maps, which are crucial for understanding complex brain functions [14][15]

Core Viewpoint - The recent research on "AAV9-mediated gene therapy for infantile Pompe disease" led by Professor Feng Zhichun represents a significant breakthrough in treating this rare genetic disorder, potentially offering a "one-shot cure" solution for patients [1][5]. Group 1: Disease Overview - Pompe disease, also known as Glycogen Storage Disease Type II, is a rare autosomal recessive disorder caused by a deficiency of the enzyme acid alpha-glucosidase (GAA), leading to glycogen accumulation in lysosomes, particularly affecting skeletal, cardiac, and smooth muscles [2][3]. - The infantile form of Pompe disease progresses rapidly, often resulting in heart failure and respiratory failure by the age of one if untreated [2]. Group 2: Current Treatment Limitations - Enzyme replacement therapy (ERT) has been the primary treatment since its introduction in 2006, significantly reducing mortality rates and improving quality of life for some patients; however, it does not penetrate the blood-brain barrier and has limitations in addressing central nervous system involvement [3][4]. - ERT requires bi-weekly administration and can be costly, with some patients developing antibodies that reduce treatment efficacy or cause allergic reactions [3]. Group 3: Gene Therapy Development - The newly developed GC301 injection, utilizing AAV9 as a vector to deliver a codon-optimized human GAA gene, aims to provide a long-lasting solution by correcting the genetic defect and restoring GAA enzyme synthesis [4][5]. - Initial trials with four infants showed promising results, with three achieving significant developmental milestones and improvements in cardiac function within a 52-week observation period [5]. Group 4: Safety and Future Directions - Preliminary findings indicate that GC301 is safe, with no severe immune-related adverse reactions reported; however, ongoing assessments are necessary to evaluate long-term safety and efficacy [6]. - Future research may explore the application of GC301 in late-onset Pompe disease and the development of personalized treatment plans based on different genotypes [7].

Group 1 - High-tech product exports from China have maintained growth for nine consecutive months, reflecting resilience in foreign trade despite complex international challenges [1][2] - In the first half of this year, China's total import and export volume exceeded 10 trillion yuan for nine consecutive quarters, with an increase of over 600 billion yuan compared to the same period last year [1] - The export of lithium batteries and wind turbine generators has seen growth rates exceeding 20%, indicating a shift towards quality and green products in foreign trade [1] Group 2 - In the first half of the year, China's mechanical and electrical product exports reached 7.8 trillion yuan, growing by 9.5%, with high-end equipment exports increasing by over 20% [2] - High-tech product exports grew by 9.2%, with significant increases in high-end machine tools, ships, and marine engineering equipment, all exceeding 20% growth [2] - The proportion of self-owned brands in high-tech product exports reached 32.4%, an increase of 1.2 percentage points compared to the same period last year [2]

Core Viewpoint - The introduction of smart meteorological monitoring systems has significantly improved the resilience and profitability of apple farmers in Yan'an, Shaanxi Province, by providing timely weather alerts and data-driven insights to mitigate the impact of extreme weather events [1][2][5]. Group 1: Technological Innovations - The "Ping An Weather" WeChat mini-program has been developed to create a comprehensive disaster prevention system, allowing farmers to monitor six key meteorological indicators that affect apple growth, with data updated every five minutes [2][3]. - A total of 1,670 portable temperature and humidity monitoring devices and 475 sets of six-element intelligent monitoring stations have been deployed in Yan'an, enhancing temperature monitoring accuracy from 5 degrees Celsius to 0.5 degrees Celsius [3][4]. Group 2: Economic Impact - In 2024, apple production in Zhidan County is expected to increase by 29,000 tons, representing a growth rate of 13.4%, while the production value is projected to rise by 172 million yuan, also reflecting a growth rate of 13.3% compared to 2023 [3][4]. - The implementation of advanced weather radar and automated rain-making equipment aims to mitigate hail damage, which has historically caused significant financial losses for farmers [4]. Group 3: Farmer Experiences - Farmers in Yan'an have transitioned from a state of uncertainty regarding weather conditions to a more secure and informed approach to apple farming, leading to sustainable development in the apple industry [5].

Core Insights - A new genetic risk scoring model for type 1 diabetes (C-GRS) has been developed by a collaborative team from Central South University and international partners, aimed at improving diabetes diagnosis and personalized treatment for the Chinese population [1][2] - The model is based on genomic data from over 2,000 type 1 diabetes patients, 1,000 type 2 diabetes patients, and 3,000 healthy individuals, and has been validated in over 20,000 diabetes patients in Hong Kong [2] Group 1 - The C-GRS model addresses the limitations of traditional diabetes classification methods, which often rely on clinical characteristics such as age of onset and body mass index (BMI) [1] - Approximately two-thirds of type 1 diabetes patients in China are adults, with many presenting atypical symptoms, complicating diagnosis [1] - The model aims to identify 20 to 40 additional type 1 diabetes cases for every 100 patients tested, enhancing early detection and risk prediction for high-risk individuals [2] Group 2 - Future plans include recruiting 3,000 newly diagnosed patients across over 80 top-tier hospitals in China for multi-center clinical research to further assess the model's clinical application [2] - The research team intends to integrate environmental factors with the C-GRS to create a more comprehensive predictive model for diabetes classification and treatment [2]