Core Viewpoint - Otsuka Pharmaceutical has signed a licensing agreement with Harbour BioMed for the exclusive global development and commercialization rights of a candidate drug targeting autoimmune diseases, excluding Greater China, with an upfront payment of $47 million [1][2]. Group 1: Licensing Agreement Details - Otsuka Pharmaceutical will pay an upfront signing fee of $47 million and will also incur additional one-time payments based on development stages and sales targets [2]. - The development costs for the candidate drug will be borne by Otsuka Pharmaceutical as it advances in the autoimmune disease sector [2]. Group 2: Candidate Drug Mechanism - The candidate drug is a "bispecific antibody" that targets two antigens, connecting target cells with immune cells (T cells) to activate T cells, which may help eliminate B cells that produce autoantibodies [2].

Core Viewpoint - The article discusses the significant drop in crude oil futures due to expectations of easing tensions in the Middle East, accelerated by President Trump's announcement of a ceasefire agreement between Israel and Iran [1][2]. Group 1: Market Reaction - Crude oil futures fell sharply, with WTI (West Texas Intermediate) August futures dropping to the range of $64 per barrel, down from approximately $67 before Trump's announcement [2]. - The price decline was notable, with a drop of over $10 from the high point of around $78.5 per barrel reached on June 22, followed by an additional decrease of about $3 [2]. Group 2: Market Sentiment - The probability of Iran blocking the strategic Hormuz Strait for energy transport, as predicted by the U.S. prediction market "Polymarket," decreased significantly from over 60% on June 22 to 27% by June 23 [2].

Core Viewpoint - The article discusses the transformation of Silicon Valley into a new hub for artificial intelligence (AI) startups, referred to as "Cerebral Valley," highlighting the shift in focus from traditional tech industries to AI innovation [4][5]. Group 1: AI Startup Landscape - The area around Hayes Valley in San Francisco has seen a surge in AI startups, with Origami Agents raising $2.5 million to develop software aimed at automating information collection and potentially replacing Google Search in that domain [4][5]. - The overall vacancy rate in Hayes Valley is only 15%, significantly lower than the 30% vacancy rate in San Francisco, indicating a vibrant startup ecosystem in this new AI-focused area [5]. Group 2: Cultural and Collaborative Environment - The concept of "Hacker Houses," such as AGI House, fosters collaboration among AI engineers, where they live and work together, hosting events like hackathons to encourage innovation [10][13]. - The culture of grassroots support for startups remains strong, with frequent networking events and hackathons that facilitate face-to-face interactions among engineers, enhancing productivity and creativity [13]. Group 3: Investment Trends - AI startups are attracting significant investment, with a total funding of $121 billion in the first quarter of 2025, marking the highest level since 2022, driven largely by contributions from OpenAI [14]. - Despite a 28% year-over-year decline in the number of funding rounds, half of the total funding is directed towards AI, indicating a strong investor interest in this sector [14].

Core Viewpoint - Japan has discovered a significant amount of rare earth mud around Minami-Torishima, with reserves exceeding 16 million tons, ranking third globally. Approximately 50% of this mud contains medium and heavy rare earth elements, which are subject to export controls by China, highlighting the importance of securing these resources for Japan's domestic industries [1][2]. Group 1 - The potential rare earth resources in Japan's waters were identified by a research team from the University of Tokyo in 2013, with the Minami-Torishima area alone estimated to hold over 16 million tons of rare earths [2]. - The Japanese government plans to initiate the development of rare earth mud starting in 2025, with a goal to establish a production system by 2028 [2][3]. - The economic feasibility of extracting rare earth mud has been evaluated, indicating that if 3,500 tons are harvested daily, profitability can be achieved across various price ranges over the past 20 years [2][3]. Group 2 - The Strategic Innovation Promotion Program (SIP) aims to extract 350 tons of rare earth mud daily after January 2027, with a focus on increasing extraction volumes [3]. - There are significant technical challenges in refining the extracted mud to usable purity levels, and environmental impacts must also be assessed [3][4]. - The geopolitical tensions between the U.S. and China have increased uncertainty in rare earth procurement, leading to production halts in some automotive and parts manufacturers in Europe and the U.S. [3][4]. Group 3 - The high barriers to entry for domestic rare earth mining and refining pose a risk to Japan's high-tech industry development, necessitating continuous technological innovation, including resource conservation and recycling [4].

编者荐语： 日经中文网开设了"日经BP精选"栏目。日经BP是日本经济新闻社媒体集团的一员，成立于1969年。作 为日本领先的B2B媒体公司，聚焦经营管理、专业技术及生活时尚三大主要领域。敬请读者关注。 以下文章来源于日经BP ，作者日经BP 日经BP . 日经BP成立于1969年4月, 隶属于日本经济新闻社集团。作为日本领先的B2B媒体公司，我们聚焦"经营 管理"、"专业技术"及"生活时尚"三大主要领域，满足客户多元化的需求。 在各国追求碳中和(温室气体的净零排放)的背景下，作为去碳化的手段之一，"氢社会"的重要性被指 出。丰田氢能Factory总负责人山形光正表示，为了实现氢社会，由"制造"、"储存"和"使用"构成的整个 氢价值链"朝着同一个方向努力非常重要"。 FCV 普及的两个关键词 通过采访汽车制造商和调查公司等得出的结论。 ( 来源：日经 Automotive 根据丰田的照片制作 ) 阅读更多内容请点击下方" 阅读原文 " （本文由日经BP提供） "燃料电池汽车(FCV)的普及并没有像10年前预期的那样取得进展。现状很艰难"，日系汽车制造商的技 术人员表达了这种危机感。燃料电池车的销量并未大幅增长， ...

日经GO 和歌山熊猫回国在即，日本粉丝排队送别 原创 阅读全文 ...

日本首相石破茂 石破原定作为北约的伙伴国参加峰会。韩国总统李在明也放弃出席…… 日本政府6月23日发布消息称，首相石破茂将取消参加北大西洋公约组织（NATO）首脑会议。石 破原定6月24日早晨出发前往举办地荷兰，作为北约的伙伴国参加会议。 日本在2022年至2024年期间与韩国、澳大利亚、新西兰一起在"IP4"框架下参加了该会议。此次 原本也就只有伙伴国参加的四国首脑会谈以及美国总统特朗普与四国的会谈等展开过调整。 韩国总统府也于22日表示，总统李在明将放弃出席北约峰会，会谈的前景在消息发布后已变得不 明朗。日本将派遣外相岩屋毅、韩国则派国家安保室长魏圣洛参会。 石破之所以放弃出席北约峰会，与美国攻击伊朗核相关设施之后变得紧张的中东局势也有关系。 因为有必要应对当地日本人的撤离等。 石破对于对美国攻击伊朗核设施持保留态度。 石破23日在首相官邸举行记者会，在被问及是否支持美国的行动时表示，"现阶段日本很难做出 明确的法律评价"。他同时表示："我们必须坚持考虑国际法上可能会有什么样的评价"。 石破表示："美国的行动表明了寻求尽快平息事态、同时阻止伊朗拥有核武器这一决心"。对美国 的行动显示出一定程度的理解，但没 ...

美国总统特朗普6月23日发布社交媒体称，以色列与伊朗已"就完全停火达成协议"。特朗普 说："衷心感谢以色列与伊朗两国展现出的持久力、勇气与智慧，终结了这场持续12天的战争"。 据称停火程序将在6小时后启动。双方将在"24小时"内逐步实施停火措施。特朗普指出，当这一系 列停火举措完成时，"战争将结束"。 这条信息于美东时间6月23日下午6点（北京时间24日上午6点）左右发布，预计停火程序将于北 京时间24日中午12点左右开始。 伊朗外长："无意进行报复性反击" 根据特朗普的发言，停火程序将由伊朗首先启动，随后由以色列接续。 6月23日，伊朗向驻卡塔尔的美军基地发射导弹，作为美军空袭伊朗核设施的报复行动。对此， 特朗普评价称这是"一次非常软弱的"攻击，"美方事前已收到通知"，并主张"和平的时机已经到 来"。 （Reuters） 这是美军首次直接攻击伊朗本土。由于伊朗是中东大国，外界一度担忧若伊朗进行强烈报复，冲 突可能蔓延至整个中东地区。 给伊朗留下退让空间 特朗普政府始终强调，美军的军事行动仅以迫使伊朗放弃核开发为目的，并不追求推翻伊朗政 权。正因为此，外界认为这可能为伊朗方面的妥协留出了一定空间。 据路透社援 ...

Core Viewpoint - The U.S. government has imposed a 50% tariff on white goods, classified as "derivative products" of steel and aluminum, starting from June 23, 2023, to promote domestic manufacturing [1][2]. Group 1: Tariff Details - The U.S. government initially imposed a 25% tariff on steel and aluminum products in March, which was later increased to 50% on June 4 [2]. - White goods affected by the tariff include washing machines, dryers, refrigerators, dishwashers, gas stoves, microwaves, and electric ovens, with tariffs based on the steel and aluminum content [2]. Group 2: Impact on Companies - South Korean, Mexican, and Chinese companies, which export significantly to the U.S., will be impacted by the increased tariffs [1][2]. - Some South Korean companies are considering expanding production of refrigerators and electric ovens domestically in the U.S. to avoid high tariffs [2]. Group 3: Strategic Intent - The Trump administration aims to strengthen U.S. domestic manufacturing through high tariffs, potentially leading to further demands for Japanese companies to shift production to the U.S. if the strategy is deemed successful [2].

Core Viewpoint - Japanese companies are significantly increasing their solar power generation capacity in the United States, with Mitsubishi Corporation planning to invest $3.9 billion to boost its capacity to 2.9 million kilowatts by 2028 [1][3]. Group 1: Investment Plans - Mitsubishi Corporation will invest a total of $3.9 billion, increasing its solar power generation capacity in the U.S. to 2.6 times the current level by 2028 [1][3]. - Itochu Corporation's subsidiary, Tyr Energy, is developing 29 projects with a total capacity of approximately 5 million kilowatts, aiming to reach about 10 million kilowatts by 2030 [4]. - SoftBank Group operates solar power stations with a total capacity of 2.55 million kilowatts across eight regions in the U.S., with plans to exceed 15 million kilowatts in the medium to long term [5]. Group 2: Market Dynamics - The U.S. solar power generation capacity is projected to reach 182 million kilowatts by 2026, a 49% increase over two years, surpassing wind power growth [3]. - The Trump administration continues to support solar power through tax incentives, which is expected to enhance installed capacity [1][5]. - The Biden administration has introduced additional tax incentives for companies using domestically produced equipment, further promoting solar energy development [5]. Group 3: Supply Chain and Local Procurement - Nexamp, partly funded by Mitsubishi, currently operates solar power stations with a total capacity of about 1.1 million kilowatts, planning to reach 2.9 million kilowatts by 2028 [3]. - Nexamp plans to switch to solar panels produced in the U.S. to mitigate the impact of tariffs, making local procurement easier compared to wind power [4]. - The shift to local procurement is seen as advantageous in the solar sector, allowing for better control over supply chains and tariff impacts [4].