FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 表格類別： 股票 狀態： 新提交 公司名稱： 無錫藥明康德新藥開發股份有限公司 呈交日期： 2025年7月11日 如上市發行人的已發行股份或庫存股份出現變動而須根據《香港聯合交易所有限公司（「香港聯交所」）證券上市規則》(「《主板上市規則》」)第13.25A條 / 《香港聯合交易所有限公司GEM證券 上市規則》(「《GEM上市規則》」)第17.27A條作出披露，必須填妥第一章節 。 | 第一章節 | | | | | | | | --- | --- | --- | --- | --- | --- | --- | | 1. 股份分類 | 普通股 | 股份類別 A | | 於香港聯交所上市 | 否 | | | 證券代號 (如上市) | | 說明 | 於上海證券交易所上市 | | | | | A. 已發行股份或庫存股份變動 | | | | | | | | | | 已發行股份（不包括庫存股份）變動 | | 庫存股份變動 | | | | | 事件 | 已發行股份（不包括庫存股份）數 目 | 佔有關事件前的現有已發 ...

Market Overview - The Hong Kong stock market showed a volatile upward trend in the morning, with the Hang Seng Index and the Hang Seng China Enterprises Index both rising over 1% at one point. By the close, the Hang Seng Index increased by 0.46% to 24139.57 points, with a total trading volume of 3239.5 billion HKD. For the week, the Hang Seng Index rose by 0.93% [1] - The current dollar index is under pressure due to crowded short positions and cooling interest rate cut expectations, which poses risks to the Hong Kong market. The fundamentals and sentiment indicators for Hong Kong stocks are weakening, with increased competition in the food delivery sector and a weakening AI narrative affecting the Hang Seng Technology Index [1] Blue Chip Performance - WuXi AppTec (02359) led the blue-chip stocks, closing up 10.46% at 88.15 HKD, contributing 4.53 points to the Hang Seng Index. The company issued a profit warning, expecting a revenue of approximately 20.799 billion RMB for the first half of 2025, a year-on-year increase of about 20.64%, and a net profit of 8.561 billion RMB, a year-on-year increase of about 101.92% [2][5] - Other blue-chip stocks included WuXi Biologics (02269) up 3.7%, Hong Kong Exchanges and Clearing (00388) up 2.95%, while China Merchants Bank (03968) and China Resources Mixc Lifestyle (01209) saw declines [2] Sector Highlights - Large technology stocks mostly rose, with Alibaba up 1.84% and Meituan up 1.18%. The biopharmaceutical sector saw significant gains, particularly in the CRO segment, with multiple stocks rising over 10% following WuXi AppTec's positive earnings forecast [3] - Brokerage stocks experienced a collective surge, with South China Financial (00619) up 100.89%, and Zhongzhou Securities (01375) up 47.47%, driven by expectations of virtual asset licenses [3][4] Cryptocurrency and Regulatory Developments - The Hong Kong Special Administrative Region's "Stablecoin Regulation" will take effect on August 1, 2025, allowing certain brokerages to provide virtual asset trading services to professional investors. This has generated significant market interest and may enhance the pricing attractiveness of the securities sector [4] - Bitcoin prices surged over 6%, reaching a new high of 117,919 USD, with other cryptocurrencies also rising. The U.S. House of Representatives has designated the week of July 14 as "Cryptocurrency Week" to discuss new regulatory frameworks [6] Steel and Semiconductor Sectors - The steel sector saw early gains, with Chongqing Steel (01053) up 4.08% and Maanshan Steel (00323) up 3.74%. Analysts suggest that ongoing "anti-involution" policies may improve the supply-demand dynamics in the steel industry [7] - Semiconductor stocks were active, with Hua Hong Semiconductor (01347) up 4.12% and SMIC (00981) up 2.22%. TSMC reported a revenue of 263.71 billion NTD for June, a decrease of 17.7% month-on-month but a 26.9% increase year-on-year [8] Notable Stock Movements - Xirui (02507) reached a new high, closing up 14.01% at 48 HKD, driven by developments in the general aviation sector [9] - NIO-SW (09866) rose 5.98% to 29.25 HKD following the announcement of its new product launch [11] - Gold stocks, particularly Laopu Gold (06181), faced significant declines, dropping 11.42% after a recent high [13][14]

FF305 | 第一章節 | | | | | | | | --- | --- | --- | --- | --- | --- | --- | | 1. 股份分類 | 普通股 | 股份類別 A | | 於香港聯交所上市 | 否 | | | 證券代號 (如上市) | | 說明 | 於上海證券交易所上市 | | | | | A. 已發行股份或庫存股份變動 | | | | | | | | | | 已發行股份（不包括庫存股份）變動 | | 庫存股份變動 | | | | | 事件 | 已發行股份（不包括庫存股份）數 目 | 佔有關事件前的現有已發 行股份（不包括庫存股 份）數目百分比 (註3) | 庫存股份數目 | 每股發行/出售價 (註4) | 已發行股份總數 | | 於下列日期開始時的結存(註1) | 2025年7月10日 | 2,485,141,055 | | 0 | | 2,485,141,055 | | 1). 其他 (請註明) | | | % | | | | | 參見B部 | | | | | | | | 變動日期 | 2025年7月11日 | | | | | | | 於下列日期結束時的結存 (註5及6) | ...

Group 1 - The Hang Seng Index closed up by 0.46%, while the Hang Seng Tech Index rose by 0.61% [1] - Chinese brokerage stocks strengthened, with Zhongzhou Securities (01375.HK) surging by 47% [1] - The biopharmaceutical sector saw a significant rebound, with WuXi AppTec (02359.HK) increasing by 10% [1] Group 2 - Sectors such as chips, insurance, and cryptocurrency experienced notable gains [1]

Core Viewpoint - The healthcare ETF, Taikang (159760), has shown a strong performance with a 1.51% increase, marking three consecutive days of gains, driven by significant rises in key stocks such as WuXi AppTec and Kelun Pharmaceutical [1][2]. Group 1: ETF Performance - As of July 11, 2025, the Taikang healthcare ETF reached a new high of 82.42 million yuan, the highest in three months [2]. - The index it tracks, the National Public Health and Healthcare Index (980016), rose by 1.45% [1]. Group 2: Company Performance - WuXi AppTec (603259) reported an expected adjusted net profit of approximately 6.315 billion yuan for the first half of the year, a year-on-year increase of about 44.43% [2]. - The company anticipates a net profit attributable to shareholders of approximately 8.561 billion yuan, reflecting a year-on-year growth of about 101.92% [2]. - Basic earnings per share are projected to be around 3.01 yuan, up approximately 106.16% year-on-year [2]. Group 3: Policy and Market Trends - The National Healthcare Security Administration has initiated a new round of adjustments to the national medical insurance drug catalog, indicating a favorable policy environment for innovative drugs [3]. - China ranks first globally in the number of original drugs developed by its enterprises, with increasing foreign capital investment in Chinese innovative drugs [3]. - The healthcare sector is expected to benefit from a comprehensive policy support system, enhancing the global market position of domestic innovative drugs [3]. Group 4: Index Composition - As of May 30, 2025, the top ten weighted stocks in the National Public Health and Healthcare Index accounted for 52.46% of the index, including major players like Hengrui Medicine and Mindray Medical [4].

Group 1 - The core viewpoint highlights the strong performance of the innovative drug ETF (560900), which saw a more than 2% increase in intraday trading, with significant trading volume and a notable rise in the underlying index [1] - The innovative drug ETF (560900) has shown impressive growth, with a weekly increase leading among comparable funds, and a substantial rise in both scale and shares over the past three months and six months [1] - WuXi AppTec's half-year performance forecast indicates a revenue of approximately 20.8 billion yuan, a year-on-year growth of about 20.64%, and a net profit attributable to shareholders of around 8.6 billion yuan, reflecting a significant year-on-year increase of approximately 101.92% [1] Group 2 - The trend of Chinese innovative drugs going global is accelerating, with the total value of License-out transactions expected to exceed $43 billion in 2024, accounting for nearly 20% of the global market [2] - The current overseas expansion models include "building ships" (self-declaration for overseas listing) and "borrowing ships" (outsourcing or establishing NewCo), with successful examples like BeiGene's Zebrutinib and Legend Biotech's Cilta-cel [2] - The total value of outbound licensing transactions reached $51.9 billion in 2024, with $48.4 billion disclosed in the first half of 2025, indicating a robust growth trajectory for Chinese innovative drugs [2] Group 3 - Morgan Asset Management is integrating its "Global Vision Investment Technology" product line to assist investors in seizing investment opportunities in quality technology companies amid a new wave of technological advancements driven by AI [2] - Various actively managed funds focus on emerging industry trends, including the Morgan Emerging Power Fund, which aims to capture opportunities in new industries, and the Morgan Smart Connectivity Fund, which targets AI-related sectors [3] - Passive investment options include the Morgan Hang Seng Technology ETF and the Morgan China Innovation Drug Industry ETF, providing investors with easy access to technology and innovative drug sectors [3]

Group 1 - The CRO (Contract Research Organization) sector is experiencing a surge in stock prices, with notable increases in companies such as Boteng Co., Ltd. (20% increase), Kailaiying (10% increase), and WuXi AppTec (9.99% increase) [1][2][3] - The Hong Kong CXO concept stocks also saw significant gains, with Kailaiying and WuXi AppTec both rising over 10% [3][4] - WuXi AppTec is projected to achieve approximately RMB 20.8 billion in revenue for the first half of 2025, representing a year-on-year growth of about 20.64%, and an adjusted net profit of approximately RMB 6.315 billion, reflecting a year-on-year increase of about 44.43% [4][5] Group 2 - The growth in performance for WuXi AppTec is attributed to its focus on meeting customer demands, expanding capabilities, and optimizing production processes [5] - The CXO sector is expected to benefit significantly from the current high demand for innovative drugs, with a new upturn in the life sciences and CXO sectors anticipated [5][6] - Analysts predict that the CXO sector will see a recovery in domestic front-end business due to supportive industrial policies and improved investment conditions [6] Group 3 - The current wave of innovation in the pharmaceutical sector is seen as a significant turning point, with a shift from following trends to creating original products, indicating a fundamental change in the industry [7][8] - Large multinational pharmaceutical companies are increasingly purchasing innovative drug patents from China, driven by pressures to lower drug prices and the expiration of patents [8]

Market Performance - Today, Hong Kong stocks showed significant movements with various companies experiencing notable gains, including Now Medical Technology (02225) which rose over 5% after a partnership with David Medical to develop "Minimally Invasive 5.0" technology [1] - Semiconductor stocks also saw an uptick, with Huahong Semiconductor (01347) increasing by 4.12%, and SMIC (01347) rising by 3.11% [1][2] - Hong Kong Travel (00308) surged over 14%, doubling its stock price in less than a month, driven by speculation in the tourism industry [1] - Meituan-W (03690) rose over 3% as it led an investment in Star Sea Map, furthering its focus on embodied intelligence [1] - The insurance sector saw broad gains, with China Pacific Insurance (02601) up 4.88% and China Life Insurance (02318) increasing by 3.19% [1] Company-Specific Developments - Alibaba-W (09988) increased over 3%, although its investment in instant retail and delivery services may impact profitability, according to HSBC [2] - Qian Shi International (00381) skyrocketed by over 55% due to a proposed digital economy collaboration involving a stablecoin mechanism [2] - Stablecoin-related stocks rose, with Guotai Junan International (01788) up 9.13% and China Everbright Holdings (00165) increasing by 4.83% [2] - Yadi Holdings (01585) gained over 4% following the announcement of a new electric vehicle replacement program [3] - WuXi AppTec (02359) opened nearly 5% higher after announcing expected revenue exceeding 20 billion yuan and a projected doubling of net profit [3] Industry Trends - The electric vehicle sector is expected to see growth due to a new replacement program, which could accelerate industry expansion [3] - The rare earth sector is also experiencing upward momentum, with Jinli Permanent Magnet (06680) rising over 5% after major players announced price increases [3] - The biotechnology sector is witnessing positive developments, with Xiansheng Pharmaceutical (02096) gaining over 3% after a collaboration with Conade Biopharmaceuticals [2][3]

Core Viewpoint - The Hong Kong stock market is experiencing a collective rise, particularly in the innovative drug sector, with leading CXO company WuXi AppTec seeing a significant increase in stock price after its earnings report [1][3]. Group 1: Market Performance - The Hong Kong stock market is showing strong performance, with the innovative drug sector leading the gains, particularly the CXO segment [1]. - WuXi AppTec's stock rose over 13% following its earnings report, contributing to the overall strength of the CXO sector [1][3]. - The Hong Kong Stock Connect innovative drug ETF (159570) increased by 1.4%, with trading volume surpassing 1.6 billion RMB, and has attracted over 5 billion RMB in the last 60 days [1][3]. Group 2: Company Earnings - WuXi AppTec reported an expected revenue of 20.8 billion RMB for the first half of 2025, representing a year-on-year growth of approximately 20.64% [3]. - The net profit attributable to shareholders is projected to be around 8.561 billion RMB, showing a year-on-year increase of about 101.92% [3]. - Adjusted net profit is expected to be approximately 6.315 billion RMB, reflecting a year-on-year growth of about 44.43% [3]. Group 3: Industry Outlook - According to Fengzheng Securities, the innovative drug sector is expected to enter a new upcycle, driven by the recovery of domestic demand and potential interest rate cuts in the U.S. [4]. - The CDMO sector is anticipated to recover quickly due to its reliance on orders from large overseas pharmaceutical companies [4]. - Guotai Junan Securities indicates that the CDMO industry has reached a bottom and is poised for recovery, with strong performance expected in 2025 [4]. Group 4: Policy and Market Dynamics - The upcoming commercial insurance policy for innovative drugs is expected to open up long-term payment avenues for the sector [7]. - The National Healthcare Security Administration has emphasized comprehensive policy support for innovative drugs, which is likely to enhance their market potential [7]. - The commercial health insurance market in China is projected to grow significantly, with premium income expected to reach 977.3 billion RMB in 2024, a year-on-year increase of 8.2% [7]. Group 5: Investment Opportunities - The Hong Kong Stock Connect innovative drug ETF (159570) has a high concentration in innovative drug companies, with the top ten holdings accounting for nearly 72% of the index [8]. - The ETF has shown a remarkable performance, with a 62.78% increase in the first half of 2025, outperforming other medical indices [8]. - The underlying assets of the ETF are Hong Kong stocks, allowing for T+0 trading, which enhances liquidity for investors [8].

Core Insights - The innovative drug sector in both A-shares and Hong Kong stocks is experiencing strong performance, with significant gains in various companies such as Boteng Co., Changshan Pharmaceutical, and WuXi AppTec [1][2] - WuXi AppTec is expected to report a revenue of approximately 20.8 billion yuan for the first half of the year, marking a year-on-year growth of about 20.64%, with net profit expected to reach around 8.6 billion yuan, a year-on-year increase of approximately 101.92% [1] - The National Healthcare Security Administration has announced a plan for the adjustment of the national basic medical insurance drug catalog and the commercial health insurance innovative drug catalog for 2025, indicating a synchronized approach to drug catalog adjustments [1] Market Performance - The innovative drug ETF (515120) saw an increase of over 2%, marking its fourth consecutive day of gains, with a net inflow of 317 million yuan over the past ten trading days [2] - The Hong Kong innovative drug ETF (513120) also rose by over 1%, with a trading volume exceeding 4 billion yuan, making it the top-performing medical ETF in the market [2] - The leading medical ETF (560260) increased by over 2%, with major stocks like WuXi AppTec and Kelaiying leading the gains [2] Industry Trends - According to Guangfa Securities, China's innovative drug development is entering a phase of intensive policy benefits, with the number of original innovative drugs developed by Chinese companies expected to reach 3,575 by the end of 2024, surpassing the United States [2] - Global pharmaceutical giants are increasingly recognizing Chinese innovative drugs, with over 30% of collaborations involving upfront payments exceeding 50 million USD coming from China [2] - The focus should be on innovative drug companies with global competitiveness and the clinical value realization of their overseas products [2][3] Investment Opportunities - Aijian Securities highlights the trend of Chinese innovative drugs going global and maintains a bullish outlook on the medical technology sector for the year, emphasizing the importance of tracking ADCs and bispecific antibodies [3] - The upcoming mid-year report season presents opportunities to identify low-base, high-growth stocks, particularly in areas like medical devices, brain-computer interfaces, and AI in healthcare [3] Related Products - Innovative Drug ETF (515120) closely tracks the China Innovative Drug Industry Index, investing in companies involved in the research, production, and sales of innovative drugs [4] - Hong Kong Innovative Drug ETF (513120) tracks the Hong Kong Innovative Drug Index and supports T+0 trading, enhancing liquidity for investors [4] - Medical ETF Leader (560260) focuses on leading companies in the medical industry, including medical services and devices [4] - Pharmaceutical and Health ETF (159938) invests across various sectors in the pharmaceutical and healthcare industry [4]