Ke Ji Ri Bao
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【科技日报】新型邻近标记技术有望精准打击癌细胞
Ke Ji Ri Bao· 2025-09-11 01:04
Group 1 - The article discusses a powerful "molecular mapping technique" known as proximity labeling technology, which allows scientists to catalyze and label the surrounding environment at specific locations within cells, enabling precise identification of specific molecules in the microscopic world [1] - Researchers from the Chinese Academy of Sciences have transformed this technology into a therapeutic tool by developing engineered nanoenzymes responsive to deep red light or ultrasound, successfully creating a powerful "treatment weapon" [1] - In mouse experiments, the team artificially created difficult-to-escape targets on tumors, which not only addresses core challenges in immunotherapy but also stimulates a robust systemic anti-tumor effect [1] Group 2 - The study reveals that in cancer immunotherapy, immune cells require strong and abundant "signals" to initiate attacks, and the natural signals on cancer cells are often sparse [2] - By chemically catalyzing reactions to increase the artificial antigen density on tumor cell surfaces by over 100 times, the researchers significantly enhanced immune recognition efficiency and killing power [2] - The engineered nanoenzymes were instructed to create a strong artificial target on cancer cells, which, when combined with a special bispecific T cell engager, effectively triggered T cells to launch a powerful attack on the targeted area [1][2] Group 3 - After the destruction of cancer cells, more tumor-associated antigens are exposed, which are then captured by antigen-presenting cells and relayed to the immune system, enabling it to autonomously recognize and attack similar cancer cells in the future [2] - The research has shown promising results in both mouse models and clinical tumor samples, paving the way for the development of smarter and more efficient next-generation immunotherapies [2] - In mouse trials, the primary tumor volume was reduced by over 80%, and the immune system activation also suppressed untreated distal tumors, demonstrating long-lasting immune memory against secondary tumor challenges [2]
遥感监测、大数据分析、人工智能决策……创新驱动国家公园治理变革
Ke Ji Ri Bao· 2025-09-11 00:56
今年是我国启动国家公园体制改革10周年。 截至今年7月,大熊猫国家公园已实现13个大熊猫局域种群栖息地连通,我国野生大熊猫总数量恢复到约1900只;东北虎豹国家公园畅通野生动物迁徙 通道,建成现代化智能化的"天空地"一体化监测体系,可实现对东北虎、东北豹的全天候、全区域动态监测、精准定位、人虎冲突预警和高效管理,东北 虎、东北豹数量分别从试点之初的27只、42只增长到70只、80只左右;武夷山国家公园将江西省武夷山区域纳入保护范围,福建、江西两省一体化开展生态 系统保护修复,新发现雨神角蟾等多个新物种,黄腹角雉数量保持在1000只左右…… 大熊猫国家公园唐家河片区景色。张蓉 摄 野生动物数量增长与生态活力提升的背后是我国国家公园十年来在体制机制改革、生态保护体系构建上的持续发力,以及科技创新的深度赋能。从科学 划定保护范围、完善保护管理制度,到推动跨区域协同保护、强化生态修复力度,国家公园为野生动物营造了稳定适宜的生存家园。 "国家公园的精细管理和可持续发展离不开可靠的监测和预警机制,自然和人为的突发事件发生具有时空偶然性和高破坏性,需要对可能的隐患进行监 测分析和提前预警。"中国科学院院士、中国工程院院士、 ...
我国应对气候变化和“双碳”工作成效显著
Ke Ji Ri Bao· 2025-09-11 00:54
Group 1 - The report highlights that China has built the world's largest and fastest-growing renewable energy system, contributing to a quarter of the global increase in green areas [1] - By June 2025, China's non-fossil energy installed capacity is expected to reach 2.22 billion kilowatts, accounting for 60.9% of total installed capacity, with nuclear power leading globally [1] - The production of photovoltaic components and lithium batteries has increased significantly, with growth rates of over 370% and 640% respectively since the 14th Five-Year Plan [1] Group 2 - China is advancing green development in key sectors, with 1.69 billion square meters of new green building area expected in urban areas by 2024 [2] - The country aims for approximately 70% of the clean transportation of bulk goods in key industries by 2024, while also enhancing ecological safety through large-scale afforestation [2] - Continuous strengthening of technological innovation and policy incentives is noted, including the establishment of key laboratories for carbon peak and carbon neutrality technologies [2]
2025年服贸会信息通信主题展举办
Ke Ji Ri Bao· 2025-09-11 00:07
Group 1 - The 2025 Service Trade Fair will be held from September 10 to 14 at Shougang Park in Beijing, featuring a "5G Smart Connection Global · Beijing Colorful Service" information and communication theme exhibition [1] - The exhibition showcases significant achievements in 5G network construction, technological innovation, and integrated application services since the commercial launch of 5G in China, with participation from major global companies like China Telecom, China Mobile, China Unicom, and China Tower [1] - The theme exhibition includes ten experiential scenarios such as smart customs clearance, communication services, smart travel, and intelligent accommodation, highlighting the international facilitation level of communication service trade [1] Group 2 - The exhibition features a unique dual narrative: a 30-year 'time comparison' showcasing the evolution of information and communication technology, and an 'insider perspective' from international guests sharing their experiences in China [2] - Interactive experiences are central to the exhibition, with a full-chain scenario covering entry and exit services, transportation, work, and home life, enhanced by a task-based engagement model and AI-guided robot tours [2]
AI技术助运营铁路桥梁“移旧换新”
Ke Ji Ri Bao· 2025-09-11 00:01
中铁第四勘察设计院桥梁院副总工王鹏宇介绍,针对道岔区连续梁改造的特殊结构和受力特点,项目团 队建立了高精度有限元分析模型,实现全过程模拟仿真。绍兴城际铁路上的这次"移旧换新",也是国内 首例道岔连续梁换梁工程,填补了道岔区改造领域的空白。 (文章来源:科技日报) 记者从中国铁建股份有限公司获悉,10日凌晨,在浙江绍兴城际铁路柯桥站施工现场,总重4000余吨的 钢箱梁应用人工智能(AI)实现毫米级精准落位,标志着国内首次在运营铁路桥梁上尝试应用AI技术 换梁取得阶段性成果,为我国既有铁路改造升级提供了新方案。 中铁二十四局柯桥站项目经理潜英飞介绍,项目引入AI系统,依托数字孪生技术构建三维模型,通过 40个高精度传感点实时采集梁体姿态数据,实现毫米级精度准确感知。该AI系统由感知、仿真、控制 三大模块组成。感知模块相当于眼睛,集成光栅、拉线传感器、应变片及北斗定位等先进技术,实时监 测梁体沉降、应力与位移;仿真模块用于推演,通过数字孪生平台可视化模拟施工全过程;控制模块依 托智能算法预测梁体运动趋势,自动纠偏并同步操控36个顶升千斤顶和10个水平顶推千斤顶,开创了铁 路多跨桥梁快速更换施工先例。 ...
奶牛多组织单细胞表达图谱问世
Ke Ji Ri Bao· 2025-09-11 00:01
记者10日从中国农业大学获悉,该校动物科学技术学院教授孙东晓团队构建了全球首个覆盖奶牛59种组 织、179万个细胞的多组织单细胞表达图谱,为解析牛重要性状遗传调控机制、推进精准育种及探索人 类疾病的牛模型研究提供了重要资源。该成果日前发表于国际期刊《自然·遗传》。 论文通讯作者孙东晓告诉科技日报记者,本研究突破技术瓶颈,采用单细胞转录组测序技术,对1头荷 斯坦奶牛胎儿、4头犊牛和10头成年荷斯坦奶牛(含公牛、母牛)的59种组织进行深度测序,最终筛选 出179万个高质量细胞,成功注释出131种细胞类型,涵盖免疫细胞、内皮细胞、上皮细胞、基质细胞、 神经细胞、肌肉细胞和生殖细胞七大细胞谱系。 "该研究填补了国际上奶牛单细胞生物学领域的空白,为奶牛遗传育种、免疫研究及比较医学提供了重 要基础数据。其技术路线与分析框架也为其他家畜单细胞图谱构建提供了参考,对推动畜禽种业育种技 术创新、保障农业动物遗传资源利用具有重要意义。"孙东晓说,本研究相关数据与分析工具可通过在 线平台供全球科研人员免费获取。 (文章来源:科技日报) 作为人类最早驯化的家畜之一,奶牛在全球粮食安全与农业生态系统中占据关键地位。传统研究多聚焦 于组 ...
99%都是水、营养物质含量低 业内专家表示——“东北神水”并无特殊养生功效
Ke Ji Ri Bao· 2025-09-10 23:58
Core Insights - The birch sap beverage has gained popularity in China, particularly in supermarkets, due to its perceived health benefits such as anti-inflammatory and anti-aging properties, aligning with consumer demand for natural health products [1][2] - Birch sap is primarily sourced from the birch tree, which is commonly found in high-latitude cold regions, especially in Northeast China, where traditional collection methods involve drilling holes in the tree trunk [1] - The collection of birch sap is time-sensitive, with specific guidelines established in the "Management Measures for Birch Sap Collection" released in March, indicating optimal collection times based on temperature and tree growth stages [1] Industry Dynamics - The rise in popularity of birch sap is driven by two main factors: the increasing consumer demand for natural, additive-free health products and the effective targeting capabilities of live-streaming e-commerce platforms [2] - Many merchants on e-commerce platforms emphasize the health benefits of birch sap, highlighting its content of trace elements like glucose, fructose, and amino acids, as well as birch triterpenes [2] - Despite its nutritional components, experts indicate that birch sap is composed of approximately 99% water, and the trace elements present do not significantly impact human health, suggesting that while it is safe to consume, it does not possess extraordinary health benefits [2]
IASP2025年世界大会即将开幕
Ke Ji Ri Bao· 2025-09-10 23:56
Core Points - The International Association of Science Parks and Areas of Innovation (IASP) will hold its 2025 World Conference in Beijing from September 15 to 19 [1] - The theme for the 2025 conference is "Pursuing Excellence - Innovation Clusters Driving High-Quality Development" [1] - The main venue will be at the National Convention Center Phase I, with a sub-venue at the Zhongguancun Life Science Park in Changping District [1] Event Details - The conference will last for five days and will include opening and closing ceremonies, plenary sessions, parallel forums, exhibitions, and cultural visits [1] - IASP is a non-profit organization with science parks as members, aiming to explore industry development trends and promote policies beneficial to technological innovation and science park development [1] - This will be the fourth time the IASP World Conference is held in China, with the last successful bid made by Beijing in 2023 [1]
国内首次应用人工智能为在营铁路桥梁“移旧换新”
Ke Ji Ri Bao· 2025-09-10 08:38
记者从中国铁建股份有限公司获悉,9月10日凌晨,在浙江绍兴城际铁路柯桥站施工现场,总重4000余吨的钢箱梁应用人工智能(AI)实现毫米级精准落 位,标志着国内首次在运营铁路桥梁上尝试应用AI技术换梁取得阶段性成果,为我国既有铁路改造升级提供了新方案。 绍兴城际铁路是利用既有萧甬铁路改造而成的跨市区域城际铁路,其中柯桥站是该线新建车站,也是国内首个在运营铁路上增设的高架城际车站。因该站由 2股道增加为4股道,需将"咽喉区"混凝土梁更换为钢箱梁。同时,该工程位于铁路干线,技术难度大、安全风险高、施工环境复杂,传统工艺难以满足要 求。 中铁二十四局柯桥站项目经理潜英飞介绍,项目引入AI系统,依托数字孪生技术构建三维模型,通过40个高精度传感点实时采集梁体姿态数据,实现毫米 级精度准确感知。该AI系统由感知、仿真、控制三大模块组成。感知模块相当于眼睛,集成光栅、拉线传感器、应变片及北斗定位等先进技术,实时监测 梁体沉降、应力与位移;仿真模块用于推演,通过数字孪生平台可视化模拟施工全过程;控制模块依托智能算法预测梁体运动趋势,自动纠偏并同步操控36 个顶升千斤顶和10个水平顶推千斤顶,开创了铁路多跨桥梁快速更换施工先例 ...
杂交玉米核不育制种技术走向产业化
Ke Ji Ri Bao· 2025-09-10 08:37
Core Insights - The article discusses the successful development of a new hybrid corn male sterility breeding technology, known as "nuclear sterility breeding technology," which has been under research for 15 years and is now ready for industrial application [1][2] Group 1: Technology Overview - The nuclear sterility breeding technology integrates transgenic maintainer lines, seed grading devices, and marker screening methods to achieve efficient propagation of male sterile lines and high-purity production of hybrid seeds [1] - This technology addresses the long-standing challenges in hybrid corn seed production, such as reliance on manual or mechanical detasseling, by enabling the use of male sterile lines to reduce production costs and enhance seed purity [1][2] Group 2: Implementation and Results - Since 2022, trials of the nuclear sterility breeding technology have been conducted in multiple regions, including Hainan, Gansu, Xinjiang, Shanxi, and Jilin, demonstrating significant industrial advantages [2] - The technology has shown to increase yields by over 10% in male sterile seed production bases compared to traditional manual detasseling methods under the same cultivation management conditions [2] Group 3: Commercialization Efforts - Sichuan Tianneng Jingxiu Biotechnology Co., Ltd. has been authorized by China Agricultural University to develop the nuclear sterility breeding technology for commercialization [2] - The company has collaborated with Chengdu Hancheng Guangyi Technology Co., Ltd. to develop an intelligent impurity removal machine that enhances impurity removal efficiency by accurately locating and cutting out undesirable plants [2] Group 4: Competitive Advantage - The nuclear sterility breeding technology is positioned as a core component in utilizing hybrid advantages, providing a significant competitive edge that will contribute to the advancement of China's biotechnology breeding industry [2]