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美国总统每年都体检,为什么没查出拜登的前列腺癌?
36氪· 2025-05-20 23:58
Core Viewpoint - The article discusses the recent diagnosis of prostate cancer in former US President Joe Biden, highlighting the implications of prostate cancer screening policies in the US and the importance of early detection [3][4][9]. Group 1: Biden's Diagnosis - Joe Biden was diagnosed with aggressive prostate cancer that has metastasized to his bones, with a Gleason score of 9 and stage 4 classification, indicating late-stage cancer [3][4]. - Biden's case raises questions about the effectiveness of routine health screenings, particularly the PSA test, which has been used for prostate cancer screening since 1991 [3][9]. Group 2: Prostate Cancer Screening Guidelines - The American Cancer Society recommends that men discuss the potential benefits and risks of prostate cancer screening with their doctors, starting at age 50 for average-risk individuals and at age 45 for high-risk groups [9][10]. - PSA levels are used to detect prostate cancer, but elevated levels can also result from benign conditions, complicating the diagnosis [11][13]. Group 3: Screening Recommendations and Risks - The article outlines that men with a PSA level of 2.5 ng/mL or higher should be re-evaluated annually, while those with lower levels should be checked every two years [14]. - The potential negative effects of widespread PSA screening include false positives, overdiagnosis, and overtreatment, which can lead to unnecessary anxiety and complications [16][17][18]. Group 4: Prostate Cancer Statistics in China - In 2022, approximately 134,200 new cases of prostate cancer were reported in China, making it the sixth most common male malignancy, with 47,500 deaths [27]. - The incidence and mortality rates of prostate cancer in urban areas of China have been rising, indicating a growing public health concern [27]. Group 5: Treatment Options - Treatment for advanced prostate cancer, such as Biden's case, typically involves androgen deprivation therapy (ADT), which aims to reduce testosterone levels to slow cancer growth [28]. - Despite advancements in treatment, prognosis is influenced by various factors, including the extent of the disease at diagnosis, with early detection significantly improving survival rates [28].
清华系具身大脑团队累计融资数亿规模,对标美国头部公司,已在行业头部厂商落地|早起看早期
36氪· 2025-05-20 23:58
Core Viewpoint - Qianjue Technology, a company focused on embodied intelligence, has recently completed a Pre-A+ round of financing amounting to several hundred million yuan, aimed at enhancing core technology, product standardization, and industrial delivery capabilities [4][8]. Group 1: Company Overview - Qianjue Technology is incubated by a Tsinghua University team, with core members primarily from the university's automation department and related AI research institutions, showcasing a high talent density in the industry [4][6]. - The company is the only domestic counterpart to the American Physical Intelligence, having achieved practical long-term task execution capabilities in real-world scenarios [4][5]. Group 2: Technology and Innovation - The core of Qianjue Technology's architecture is the general-purpose "embodied brain," which plays a central decision-making role, directly influencing the robot's autonomous execution capabilities and expanding application boundaries [5][6]. - The "embodied brain" system emphasizes multi-modal real-time perception, continuous task planning, and autonomous execution without pre-set strategies, aligning closely with Physical Intelligence's recently released π0.5 model [5][6]. Group 3: Performance and Demonstrations - Qianjue Technology's embodied brain has demonstrated cross-environment, non-pre-set, and long-duration capabilities, with the ability to adapt to over twenty types of embodied hardware forms [6][8]. - The company has conducted over a hundred live demonstrations, with the longest lasting over two hours, showcasing the system's ability to operate autonomously in unstructured environments [7][8]. Group 4: Commercialization Progress - The embodied brain has achieved stable operation in various scenarios, including home services, logistics, and commercial operations, and has established partnerships with leading embodied robot manufacturers and tech companies [8]. - Supported by key projects in Chinese brain science, Qianjue Technology has built the world's largest pure real-sampling home scene dataset, demonstrating strong generality and cross-task adaptability [8].
无纺布袋堆成山,平台送的袋子只能装垃圾?
36氪· 2025-05-20 23:58
Core Viewpoint - The article discusses the growing issue of excess non-woven bags provided by local lifestyle platforms, highlighting their environmental implications and the challenges consumers face in repurposing them [6][15][44]. Group 1: Consumer Behavior - Consumers are increasingly receiving non-woven bags as free gifts from local lifestyle platforms, leading to an accumulation of these bags at home [6][20]. - Many consumers express frustration over the inability to effectively utilize or recycle these bags, resulting in them being discarded or stored away [11][44]. - The article notes that over 40% of respondents are unwilling to reuse non-woven bags due to poor quality or unattractive appearance [44]. Group 2: Environmental Impact - Non-woven bags, often made from polypropylene, have a slow degradation process similar to traditional plastic bags, raising concerns about their environmental footprint [38][39]. - The production of non-woven bags may generate more carbon emissions than that of plastic bags, emphasizing the importance of repeated use to mitigate environmental damage [39]. - The lack of recycling options for non-woven bags contributes to their accumulation in households, creating a paradox of being marketed as eco-friendly alternatives while posing disposal challenges [40][41]. Group 3: Innovative Uses and Consumer Creativity - Consumers are exploring various creative uses for non-woven bags, such as using them for pet waste, as temporary mats at events, or for storage [26][31]. - The emergence of "non-woven bag storage techniques" on social media indicates a shift towards finding practical applications for these bags [24]. - Despite attempts to sell excess bags on second-hand platforms, there is little demand, highlighting the difficulty in repurposing them effectively [34]. Group 4: Market Dynamics - The article suggests that as consumer spending power increases and e-commerce platforms expand, the issue of excess non-woven bags may worsen [47]. - There is a generational shift in attitudes towards accumulation, with younger consumers more inclined to seek innovative uses rather than simply hoarding [48][50]. - Businesses face pressure to provide bags to avoid negative feedback, creating a cycle of excess that consumers must navigate [46].
奥迪的中产神车,跌到13万多了
36氪· 2025-05-20 13:25
Core Viewpoint - The article discusses the significant price reductions in the luxury car market, particularly focusing on brands like Audi, BMW, and others, as they struggle to maintain sales amidst the rise of electric vehicles and changing consumer preferences [4][10][22]. Group 1: Price Reductions and Market Dynamics - Luxury car brands are experiencing drastic price cuts, with Audi A3 being advertised at prices as low as 12.49 million yuan, leading to comparisons with lower-end vehicles [7][17]. - The article highlights the emotional impact on existing car owners who purchased vehicles at higher prices, now facing depreciation and feelings of being undervalued [20][24]. - The overall sales figures for Audi show a decline, with global sales expected to drop by 11.8% in 2024, indicating a broader trend of struggling luxury brands [22][30]. Group 2: Consumer Sentiment and Brand Perception - The frequent price changes are likely to damage the brand image of luxury car manufacturers, as consumers may perceive them as lower quality or less prestigious [26][28]. - The article notes that traditional luxury brands are at risk of losing their market position as new consumer preferences shift towards technology and smart features over traditional luxury attributes [31][32]. Group 3: Strategic Responses from Luxury Brands - In response to market pressures, luxury brands are adopting strategies such as partnerships with technology companies like Huawei to enhance their offerings [39][40]. - The article mentions the importance of localization in production and technology to better meet the demands of the Chinese market, with brands like Lexus investing in local manufacturing [44]. - Financial strength is highlighted as a key advantage for traditional luxury brands, with BBA (BMW, Benz, Audi) planning to invest over 350 billion euros in 2024 to support their transition and innovation efforts [47].
赴港IPO,宁德时代的AB面
36氪· 2025-05-20 13:25
Core Viewpoint - The article discusses how CATL (Contemporary Amperex Technology Co., Limited) is transitioning from a leading battery manufacturer to a zero-carbon technology company, emphasizing the importance of innovation and crisis awareness in maintaining its market leadership [3][19][34]. Group 1: Innovation and Market Leadership - CATL has maintained a dominant position in the global battery market, holding nearly 40% market share since 2017, with one in every three electric vehicles globally equipped with its batteries [9][10]. - The company has invested approximately 71.8 billion RMB in R&D from 2015 to 2024, with nearly 37 billion RMB allocated in 2023 and 2024 alone, surpassing the funds raised from its recent IPO [10][34]. - CATL's innovations include the development of the Kirin and Shenxing batteries, which enhance performance and efficiency, and the recent introduction of the Xiaoyao dual-core and sodium-ion batteries, showcasing its commitment to advancing battery technology [12][13]. Group 2: Transition to Zero-Carbon Market - CATL aims to achieve carbon neutrality in core operations by 2025 and across the entire value chain by 2035, with plans to produce zero-carbon batteries [24][27]. - The company is expanding its zero-carbon initiatives beyond battery production, seeking to create a comprehensive zero-carbon ecosystem that includes energy production, storage, and consumption [24][30]. - Collaborations with companies like Moutai to develop zero-carbon factories highlight CATL's role in driving the green transformation of traditional industries [25][28]. Group 3: Strategic Market Positioning - The recent IPO on the Hong Kong Stock Exchange raised approximately 35.3 billion HKD (about 32.5 billion RMB), positioning CATL for further global expansion [34]. - The strategic partnerships and investments from sovereign funds and multinational automotive companies indicate a strong international market presence and support for CATL's growth [34]. - The focus is shifting from merely maintaining market share in battery production to exploring new business models in the zero-carbon market, reflecting a broader industry trend towards sustainability [35][36].
开放式关系、已婚单身、前任炮友……我们扒光了36段「非正常关系」
36氪· 2025-05-20 13:25
Group 1 - The article discusses the evolving nature of romantic relationships among young people, highlighting the complexity and diversity of modern love, which often defies traditional labels [4][5][6] - A survey conducted by "后浪研究所" revealed that only 55% of respondents identifying as single are truly "full-time single," while the rest are in various ambiguous relationships [6][9] - The concept of "full-time single" is defined as a state devoid of any emotional connections, while nearly half of the respondents are in "relative single" states, involving situations like ambiguity, sexual partners, or lingering ties with exes [7][9] Group 2 - The article presents various personal stories from respondents who describe their "non-normal" relationship statuses, showcasing a wide range of emotional and physical connections [10][19][21] - Over half of the young respondents are open to accepting open relationships, with nearly 20% having tried such arrangements, indicating a shift in sexual attitudes [26][29] - The traditional view of relationships is challenged, as many young people prioritize emotional freedom and flexibility over conventional commitments, reflecting a broader societal change [29][69]
价格过千,维修隐藏式门把手为何这么贵?
36氪· 2025-05-20 13:25
Core Viewpoint - The article discusses the rising costs associated with the repair of hidden door handles in electric vehicles compared to traditional mechanical handles, highlighting the complexity and electronic components involved in the former [4][11][22]. Group 1: Repair Costs Comparison - Repair costs for hidden door handles are significantly higher than for mechanical handles, with examples showing costs of 1087.5 yuan for a hidden handle versus 120 yuan for a mechanical one [5][9]. - The average repair costs for hidden handles range from 400 to 1000 yuan for materials, with additional labor costs, while mechanical handles typically cost under 300 yuan for replacement [8][9]. Group 2: Reasons for High Repair Costs - Hidden door handles incorporate multiple electronic components such as motors and sensors, leading to higher replacement costs compared to traditional handles [11][14]. - The common practice in repairs is to replace the entire handle assembly rather than individual components, further driving up costs [12][16]. Group 3: Industry Challenges - There is a significant shortage of skilled technicians capable of repairing electronic components, which forces many repair shops to adopt a replacement-only approach, increasing costs for consumers [18][21]. - The automotive repair industry faces a talent gap, particularly in the field of electric vehicle maintenance, with estimates indicating that 80% of the talent shortage is in this area [21][23]. Group 4: Potential Solutions - Suggestions to address high repair costs include improving vocational training for technicians, establishing a certification system for repair professionals, and encouraging competition among parts suppliers to lower costs [20][23]. - The article emphasizes the need for policy support and industry self-regulation to enhance the repair ecosystem for electric vehicles [20][23].
鸿蒙电脑,靠国产软件能用起来吗?
36氪· 2025-05-20 08:33
国产系统+国产软件,这条路很难,但应该多点耐心。 以下文章来源于爱范儿 ,作者发现明日产品的 爱范儿 . 关注明日产品的数字潮牌 鸿蒙电脑的目标就是实现生态闭环,所以多端互联是它最核心的功能。 能不能装微信? 这是最多人问的问题。现在鸿蒙电脑上的应用市场里没有微信,也没有企业微信,但是有飞书和钉钉。那要怎么聊微信呢? 我找到了一个最方便的方法,那就是,用手机微信聊。 文 | Lin 来源| 爱范儿(ID:ifanr) 封面来源 | 华为官网 华为鸿蒙生态最重要的一环,也就是电脑端的鸿蒙系统。 快速上手我们之前已经发过了,今天我就着重分享一下,我在使用了手机、平板和电脑组成的鸿蒙全家桶之后,发现了哪些不为人知的细节,同时回答几个 大家问得最多的问题。 除了刚才讲的"多屏协同",手机平板还可以和电脑共享鼠标,文件也能跨屏直接拖。 不是直接拿手机,而是用"多屏协同",手机放在旁边,用电脑就能操控。 手机互联怎么样? 虽然有点曲线救国的意思,但这是目前用下来最省事儿的方法。 不过还有另一种方式,你绝对想不到,我一会给你说。 键盘可以共享,快捷键也可以正常用。还可以实现眼睛看到哪台,鼠标瞬移到哪台,非常神奇。 除此以外 ...
一家FA决定做孵化丨入局
36氪· 2025-05-20 08:33
Core Viewpoint - The article discusses the successful fundraising and strategic focus of Lighthouse Founders' Fund (L2F) by Light Source Capital, emphasizing its commitment to early-stage investments in AI and frontier technology, aiming to leverage the current AI development phase similar to the mobile internet era from 2009 to 2014 [3][4][8]. Fundraising and Investment Strategy - L2F has successfully raised at least $50 million, with plans to invest between $300,000 to $2 million in seed and angel round companies, targeting ten investments per year [3][4]. - The fund has already prepared 15 projects, with 5 investments made, including a leading AI mining exploration company, Lingyun Zhikang, which integrates AI with geological exploration [4][5]. Market Context and Opportunities - The current AI landscape is compared to the early mobile internet era, where many opportunities arise amidst a lack of consensus, making it an ideal time for incubation and investment [9][10]. - AI is viewed as a transformative productivity tool that can be applied across various industries, enhancing its global applicability and demand [9][10]. Unique Value Proposition - Light Source Capital's unique position stems from its extensive network and resources, having collaborated with over 100 listed companies, allowing it to facilitate strategic partnerships and funding for startups [20][21]. - The fund's LPs include successful entrepreneurs and industry leaders, providing a robust advisory committee to support portfolio companies [4][30]. Incubation Approach - The incubation process is divided into three stages: identifying potential entrepreneurs, aligning them with market needs, and achieving product-market fit, with a focus on deep engagement and resource allocation [27][29]. - The fund aims to create a dual-engine model with its incubator, enhancing early-stage investment capabilities through strategic collaboration [25][30]. Future Outlook - The fund is positioned as a key strategic initiative for Light Source Capital, aiming to become a leading player in the early-stage investment landscape, particularly in AI and related technologies [30][31].
估值六年无明显增长,二次闯关的溜溜果园急需上市输血|智氪
36氪· 2025-05-20 08:33
Core Viewpoint - The article discusses the IPO attempt of Liu Liu Guo Yuan (Liu Liu Mei) and highlights its financial performance, market positioning, and the reasons behind its timing for going public [4][5][14]. Financial Performance - Liu Liu Guo Yuan's revenue increased from 873 million RMB in 2018 to 1.616 billion RMB in 2024, with net profit rising from 56 million RMB to 148 million RMB during the same period [4]. - The company achieved a compound annual growth rate (CAGR) of 17.32% in revenue from 2022 to 2024, with specific product lines showing significant growth: dried plum snacks at 9.79%, western plum products at 35.5%, and plum jelly at 33.51% [7][8]. Product and Revenue Breakdown - In 2024, the revenue breakdown was as follows: dried plum snacks contributed 974 million RMB, western plum products 224 million RMB, and plum jelly 410 million RMB [7]. - The sales channels have shifted significantly, with direct sales increasing from 14% of total revenue in 2018 to 59.2% in 2024, while distribution channels decreased from 74.5% to 40.8% [10]. Customer Base and Market Strategy - The top five customers accounted for 33.1% of revenue in 2024, up from 12.7% in 2022, indicating a growing reliance on major retail partners [11]. - The company has strategically aligned itself with rapidly expanding offline snack retail stores, which has contributed to its revenue growth [13][14]. Profitability Metrics - Liu Liu Guo Yuan's gross margin fluctuated from 38.6% in 2022 to 36% in 2024, influenced by the changing customer structure and the pricing strategies of large clients [16][18]. - Net profit margins improved from 5.83% in 2022 to 9.14% in 2024, attributed to economies of scale and reduced operating expenses [19]. Capital Structure and Funding Needs - As of 2024, the company had total assets of 1.671 billion RMB and total liabilities of 1.053 billion RMB, resulting in a debt-to-asset ratio of 63% [21]. - Liu Liu Guo Yuan faces potential liquidity issues due to a low inventory turnover rate of 2.18, significantly below industry averages [22]. - The company is under pressure to secure funding through its IPO to address its capital structure and meet short-term liabilities [27][28]. Market Valuation - The expected compound annual growth rate for the Chinese dried plum snack market is 13.65%, with Liu Liu Guo Yuan projected to grow at a CAGR of approximately 21% from 2024 to 2029 [30]. - The estimated valuation for Liu Liu Guo Yuan could reach around 2.768 billion RMB based on a price-to-earnings ratio of 18.7, which is higher than its last funding round valuation of 2.2 billion RMB [30].