Investment Rating - The report initiates coverage on 康龙化成 (300759 CH) with a "Buy" rating and a target price of 38.08 RMB, indicating a potential upside of 21.7% from the current price of 31.30 RMB [1][3]. Core Insights - 康龙化成 is recognized as a leading integrated CXO service provider in China, benefiting from the growing global demand for pharmaceutical R&D outsourcing. The company offers end-to-end services across the entire drug development lifecycle, positioning itself to capitalize on the increasing outsourcing needs in the pharmaceutical industry [1][7]. - The report highlights the company's strategic expansion into small molecule CDMO, clinical development, and large molecule & cell and gene therapy (CGT) sectors, creating a comprehensive one-stop CXO platform that reduces operational risks and costs for clients [7]. - The company is expected to see revenue growth of 14.2% in 2025, 14.8% in 2026, and 16.3% in 2027, with adjusted net profit growth projected at 12.3%, 17.8%, and 18.7% for the same years [7][8]. Financial Summary - For FY23A, 康龙化成 reported sales revenue of 11,538 million RMB, with a year-on-year growth of 12.4%. The adjusted net profit for the same period was 1,903 million RMB, reflecting a growth of 3.8% [2][11]. - The company’s sales revenue is projected to reach 14,022 million RMB in FY25E, with a corresponding adjusted net profit of 1,804 million RMB, indicating a year-on-year increase of 12.3% [2][11]. - The adjusted earnings per share (EPS) for FY25E is estimated at 1.01 RMB, with a forward P/E ratio of 30.8 times [2][11]. Shareholder Structure - The shareholder structure indicates that 19.3% of the shares are held by Hong Kong investors, while the actual controller holds 17.7% [4]. Stock Performance - The stock has shown a 1-month absolute return of 8.6% and a 6-month return of 15.1%, outperforming the market in these periods [5].

Group 1 - Leading private equity firms are increasing their positions, with stock private equity positions rising above 81% as of January 9, 2026, marking an increase of over 1 percentage point from the end of 2025 [1] - The first week of 2026 saw a significant increase in positions among large private equity firms, with an average increase of nearly 8 percentage points [1] - The capital market is expected to continue its structural trends in 2026, driven by reduced external uncertainties, low interest rates, and solidifying corporate earnings [1] Group 2 - The A-share market has seen a significant reduction in the total shares of major broad-based ETFs, indicating a major reallocation by the "national team" [2] - The latest public fund quarterly reports confirm that major ETFs like Huatai-PB CSI 300 ETF and Huaxia SSE 50 ETF have seen their total shares drop below the holdings of the central financial authority [2] Group 3 - Over 50 biopharmaceutical companies have released performance forecasts for 2025, with nearly half indicating positive expectations [3] - Leading CXO companies, such as WuXi AppTec, are projected to achieve significant revenue growth, with an expected revenue of approximately 45.46 billion yuan, a year-on-year increase of about 15.84% [3] - The biopharmaceutical industry is anticipated to enter a new phase of high-quality development in 2026, supported by ongoing policy and financing improvements [3] Group 4 - The gold jewelry market is experiencing a shift from weight-based pricing to value-based pricing, with brands introducing fixed-price products that appeal to younger consumers [4] - Upstream companies are benefiting from rising gold prices, which are expected to enhance profitability [4] Group 5 - The commercial space sector in China is entering a new phase focused on large-scale launches and commercial viability, with significant advancements expected in the next 3 to 5 years [5] - In 2025, China's commercial space sector completed 50 launches, accounting for 54% of total space launches, indicating a rapid acceleration in commercialization [5] Group 6 - The domestic GPU manufacturer, Shanghai Suiruan Technology, has received approval for its IPO on the Sci-Tech Innovation Board, aiming to raise 6 billion yuan [6] - The company is part of a growing trend of domestic tech firms seeking public funding to support their growth [6]

Core Insights - The JPM conference highlighted breakthroughs in ADC, IO dual antibodies, and GLP-1 technologies by Chinese pharmaceutical companies, enabling them to expand globally through licensing and collaborative development [1] - Leading companies have successfully organized their international operations, with some biotech firms achieving breakthroughs in niche areas [1] - The CXO sector is experiencing significant growth, with companies leveraging the CRDMO model and global production capacity, resulting in a continuous increase in orders [1] - By 2026, overseas bases are expected to be densely operational, marking the beginning of a commercialization phase for the industry [1] - Overall, the Chinese pharmaceutical industry is at the starting point of a global value reassessment, with 2026 identified as a critical year for validating transformation outcomes [1]

● 本报记者 李梦扬 根据同花顺iFinD数据，截至1月22日记者发稿时，按照申万一级行业划分，已有逾50家生物医药企业披 露2025年业绩预告，27家预喜，预喜比例近五成。值得关注的是，多家CXO（医药外包服务，包括 CDMO和CRO）公司业绩表现亮眼。其中，CXO行业龙头药明康德预计2025年实现营业收入约454.56亿 元，同比增长约15.84%；实现归母净利润约191.51亿元，同比增长约102.65%。 业内人士表示，随着全球投融资逐步恢复、国内对创新药行业的持续支持以及新药研发逐步回暖， CXO产业趋势向好。2026年，随着行业结构性改革深化、政策与融资环境持续优化，中国医药产业提 质升级趋势明确，行业将迈向高质量发展新阶段。 27家生物医药公司业绩预喜 在已披露业绩预告的超50家生物医药公司中，27家预喜，其中，18家预增，5家略增，4家扭亏。从归母 净利润金额看，药明康德预计2025年实现归母净利润191.51亿元，位居第一；以岭药业、甘李药业、兴 齐眼药、华邦健康等公司居前，预计归母净利润下限均超5亿元。 剔除扭亏影响，从归母净利润同比变动下限看，上海谊众、康辰药业、特一药业、昭衍新药等多家 ...

Investment Rating - The industry investment rating is "Positive" [2] Core Insights - The report indicates a significant recovery in domestic innovative drug financing, with 512 events in 2025, a year-on-year increase of approximately 18%, and a total financing amount of $14.684 billion, up about 127% [3][14] - The report highlights that the secondary market played a crucial role in this recovery, with secondary market financing amounting to $9.466 billion, a year-on-year increase of approximately 317% [3][14] - The report notes that the overseas innovative drug financing events reached 754 in 2025, a year-on-year decrease of about 16%, with a total financing amount of $42.136 billion, down about 22% [4][23] - The report emphasizes the strong growth potential of companies like WuXi AppTec, WuXi Biologics, WuXi AppTec, and Tigermed, with each company showcasing impressive revenue growth forecasts and strategic initiatives [5][6][8][9] Summary by Sections 1. Domestic Innovative Drug Financing - In 2025, domestic innovative drug financing events totaled 512, with a financing amount of $14.684 billion, marking a 127% year-on-year increase [3][14] - The secondary market's contribution was significant, with financing amounting to $9.466 billion, reflecting a 317% increase [3][14] 2. Overseas Innovative Drug Financing - Overseas financing events reached 754 in 2025, with a total amount of $42.136 billion, representing a 22% decline [4][23] - The report notes that the Federal Reserve's interest rate changes have impacted financing costs, with a slight recovery observed in late 2025 [4][23] 3. Company Highlights - WuXi AppTec expects a revenue of approximately $45.456 billion in 2025, a year-on-year increase of about 15.84%, with adjusted net profit projected to grow by 41.33% [5][31] - WuXi Biologics reported a significant increase in dual-target antibody projects, contributing nearly 20% to total revenue, with a year-on-year growth exceeding 120% [6][35] - WuXi AppTec's acquisition of Easton Pharma is expected to enhance production capacity, with projected revenue growth exceeding 45% in 2025 [8][45] - Tigermed anticipates a robust demand in the clinical CRO sector, with a projected compound annual growth rate (CAGR) exceeding 12% from 2025 to 2028 [9][51]

Core Insights - The international competitiveness of domestic pharmaceutical companies in China is continuously improving, driven by new technologies and supportive national policies for innovative drug development [1][2] - The CXO sector is expected to see significant performance turning points as companies with high overseas business ratios are favored [1] Group 1: Industry Trends - The JPM conference highlighted breakthroughs in technologies such as ADC, IO dual antibodies, and GLP-1, enabling Chinese pharmaceutical companies to expand globally through licensing and collaborative development [1] - Major companies like BeiGene have successfully established international operations, while some biotech firms have achieved breakthroughs in niche areas [1] - The Chinese pharmaceutical industry is at the starting point of a global value reassessment, with 2026 being a critical year for validating transformation outcomes [1] Group 2: Domestic Pharmaceutical Companies - Domestic pharmaceutical companies are accelerating their globalization, characterized by several core trends: 1) Comprehensive iteration of technology platforms such as ADC, multi-antibodies, and small nucleic acids, leading to multiple BIC/FIC potential assets 2) Accelerated internationalization with over $10 billion in transactions with multinational corporations (MNCs) and a continuous rise in innovative drug licensing revenues 3) The year 2026 will see a concentrated period of catalysts for domestic companies, with many initiating global registration studies, key data readouts, and new product applications, showcasing both individual breakthroughs and overall sector acceleration [1] Group 3: CXO Sector Developments - The JPM conference underscored a historic opportunity for the Chinese CXO industry to transition from a "cost advantage" model to a "technology + scale" dual-driven approach [2] - Chinese CXO companies are evolving from "intermediate suppliers" to "global innovation enablers" through their one-stop service platform capabilities in areas like ADC, dual antibodies, and GLP-1 [2] - By 2026, both domestic and international innovations are expected to enter a concentrated catalyst period, with Chinese CXO companies experiencing sustained growth in orders and entering a phase of overseas capacity release [2]

Core Viewpoint - The new policy from the National Healthcare Security Administration (NHSA) is expected to significantly boost the medical device industry, particularly benefiting high-end surgical assistance technologies, robotic surgeries, and telemedicine [1][3]. Group 1: Market Reaction - A-share medical ETFs, particularly the largest medical ETF (512170), saw a rise of 1.36% during intraday trading, indicating strong buying interest with over 270 million yuan invested the previous day [1]. - The Hong Kong medical ETF (159137) also experienced a rebound, reaching a peak increase of 1.78% before closing up 1.06%, ending a four-day decline [1]. - Notable stock performances included a 17.3% surge in the leading domestic surgical robot company, MicroPort Scientific Corporation-B, and over 5% increases in MicroPort Medical and Xianjian Technology [1]. Group 2: Policy Impact - The NHSA's new guideline establishes a market mechanism for high-end surgical assistance technologies, which is expected to enhance innovation and profitability in the industry [3]. - The unified pricing framework is anticipated to highlight the cost-performance advantages of domestic surgical robots and related consumables, accelerating the trend of domestic substitution [3]. - The NHSA's commitment to expanding the guideline in the future will create more opportunities for innovative medical device products, benefiting the overall innovation ecosystem in the industry [3]. Group 3: Investment Opportunities - The medical device sector is poised for significant investment opportunities due to the new NHSA policy, with a focus on high-end medical equipment, robotic surgeries, and compliant consumables [3]. - The CXO industry is experiencing improved conditions due to recovering overseas orders and domestic capacity clearance, contributing to sustained growth [3]. - The largest medical ETF (512170) and its associated funds focus on medical devices and services, with over 36% of its index weight in AI medical and brain-computer interface concept stocks [4].

Group 1 - The JPMorgan Healthcare Conference (JPM2026) commenced on January 12 in San Francisco, showcasing 24 Chinese innovative pharmaceutical companies through main stage presentations and Asia-Pacific sessions [1] - Notable companies such as BeiGene, Zai Lab, Ascentage Pharma, and Legend Biotech presented their latest research and commercialization achievements, alongside CXO companies like WuXi AppTec and WuXi Biologics [1] - The report titled "2026 Global M&A Annual Outlook" indicates that global M&A transaction volume surged to $5.1 trillion in 2025, with the healthcare sector leading with a 44% increase [1] Group 2 - Analysts predict that medium-sized transactions valued between $5 billion and $15 billion will remain active in 2026 [1] - The Hang Seng Biotechnology Index focuses on innovative drug "crown jewels," highlighting three main advantages: concentration of leading companies, scarcity of futures liquidity, and high elasticity & high Sharpe ratio [1] - Investors looking for convenient access to core leaders in innovative pharmaceuticals are encouraged to consider the Hang Seng Biotechnology ETF (520933) for streamlined investment [1]

1月21日早盘，港股医疗板块盘初下探后持续走强。截至10:29，中证港股通医疗主题指数上涨1.4%，成 分股中，微创机器人-B涨超12%，微创医疗涨超4%，阿里健康涨超3%。 消息面上，在2026年1月举办的J.P. Morgan医疗健康大会上，全球药企密集披露前沿研发管线与大额BD 交易，为CXO行业带来明确订单预期。与此同时，AI医疗在C端的渗透正在加速，从智能问诊到慢病管 理的应用场景不断拓展，推动阿里健康、京东健康等港股互联网医疗平台价值重估。 有分析指出，当前医疗板块具备多重投资机会。CXO行业在海外订单回暖和国内产能出清的双重推动 下，景气度持续提升且估值仍具修复空间；医疗器械领域受益于国内设备更新政策支持与海外市场拓 展，脑机接口、AI影像等前沿方向催化不断；互联网医疗则在医保支付改革深化背景下，平台运营效 率持续优化，盈利增长曲线愈发清晰。 中证港股通医疗主题指数从港股通证券范围内选取50只业务涉及医疗器械、医疗商业与服务、制药与生 物科技服务等领域的股票作为指数样本，重点覆盖CXO与互联网医疗等港股特色标的。港股通医疗ETF 易方达（520850）跟踪该指数，可助力投资者精准把握医疗产业创新 ...

Investment Rating - The industry investment rating is "Outperform the Market," indicating that the industry index is expected to perform better than the market by more than 5% over the next six months [31]. Core Insights - The JPMorgan Healthcare Conference highlighted six top candidate drugs in the Chinese market for 2026, with four originating from local innovative companies, showcasing their R&D capabilities that can compete with multinational brands [4]. - The report anticipates continued active merger and acquisition (M&A) transactions in the biopharmaceutical sector, with a projected global M&A transaction volume reaching $5.1 trillion in 2025, led by a 44% increase in the healthcare sector [4]. - Investment strategies suggest focusing on innovative Chinese pharmaceutical companies that are enhancing their global competitiveness, particularly in therapeutic areas like metabolism, chronic diseases, and central nervous system disorders, as well as potential technology platforms such as small nucleic acid drugs and CAR-T therapies [5]. Summary by Sections Industry Overview - The JPMorgan Healthcare Conference showcased 24 Chinese innovative pharmaceutical companies, including BeiGene and Legend Biotech, presenting their latest R&D and commercialization achievements [4]. - The report emphasizes the importance of the Chinese market, identifying six candidate drugs that are expected to make significant impacts in 2026 [4]. Investment Strategy - The report recommends focusing on innovative therapeutic areas beyond traditional oncology and immunology, such as metabolic disorders and chronic diseases [5]. - It also highlights the potential of emerging technology platforms, suggesting investment in companies that are advancing in areas like peptide drugs and small nucleic acids [5]. Market Performance - The pharmaceutical sector experienced a decline of 0.68% last week, while the Shanghai and Shenzhen 300 Index fell by 0.57%, ranking the pharmaceutical industry 17th among 27 sectors [20]. - In contrast, the Hong Kong pharmaceutical sector saw an increase of 2.38%, outperforming the Hang Seng Index, which rose by 2.56%, ranking 6th among 11 sectors [30].