Core Insights - The city of Jiaozuo in Henan province has been optimizing its innovation ecosystem and enhancing its innovation system through collaboration with educational institutions and technology partnerships, leading to a high-tech industry value-added rate of 56.5% of the industrial value-added in regulated enterprises [1][2] - Jiaozuo's technology expenditure growth rate is the highest in Henan province, and its comprehensive technology innovation level index ranks third in the province [1] - The establishment of a co-innovation park by the Henan Academy of Sciences and Qinyang City has created a collaborative research model that involves entrepreneurs proposing challenges, scientists providing solutions, and government support, resulting in local retention of projects, enterprises, and talent [1] Innovation Models - Jiaozuo has developed a multi-faceted innovation model that includes "government staging, enterprises taking the lead" (government-enterprise co-creation), "platform establishment and result transformation" (independent co-creation), and "technology introduction and product export" (school-enterprise co-creation) [2] - The Ma Village District is leveraging its biopharmaceutical industrial park to explore a cooperation mechanism among research institutions, production enterprises, and medical institutions, resulting in the cultivation of two startup companies [2] - The city has seen significant growth in innovation, with 10 new provincial innovation leading enterprises and 51 high-tech enterprises added last year, and 923 companies receiving guidance for cultivation this year [2]

Core Insights - The completion of the Human Genome Project in 2003 has provided a foundational understanding of life, yet challenges remain in interpreting this vast amount of genetic data. The launch of the Genos model by BGI Life Sciences and Zhijiang Laboratory aims to address these challenges by offering a deployable genomic universal foundational model with 100 billion parameters [1]. Group 1: Genos Model Advantages - Genos enhances both interpretative and deployment capabilities compared to existing models, primarily due to the expansion of training data. It integrates multiple authoritative public resources, including the Human Pan-Genome Reference Consortium (HPRC) and the Human Genome Structural Variation Consortium (HGSVC), utilizing 636 high-quality human genomes to better reflect human genetic diversity [2]. - The model's deployment capability is improved through a "mixed expert" architecture, which efficiently coordinates relevant algorithms to reduce inference costs and resource consumption, addressing the common issue of large models being difficult to deploy. Genos is also open-source, available in both 1.2 billion and 100 billion parameter versions on platforms like HuggingFace and Modao [2]. Group 2: Clinical and Research Implications - Clinical testing has demonstrated Genos's effectiveness, achieving a 92% accuracy rate in interpreting pathogenic mutations, which increases to 98.3% when combined with scientific foundational models. This performance surpasses existing top-level models [2]. - In research, AI models like Genos can transform the process of identifying pathogenic loci from a "needle in a haystack" approach to "precise navigation," significantly reducing the time required for rare disease and complex mechanism studies [3]. Group 3: Future Prospects and Challenges - The advancement of AI models in genomics is expected to shift drug development from a "trial-and-error" approach to "design-based" innovation, thereby reducing experimental iterations and costs [4]. - Future development faces three main challenges: expanding training databases to include more disease samples, establishing comprehensive ethical and safety standards, and enhancing interdisciplinary collaboration to integrate AI with clinical data systems and biological experimental platforms [4]. - The successful implementation of AI in genomics is anticipated to accelerate the arrival of precision medicine, with the Genos model being a significant step towards unlocking the potential of the life economy [4].

随着以外卖骑手、网约车司机等为代表的新职业群体迅速壮大，国家持续拓宽就业渠道、助力新业态发 展。刘天强告诉记者，得益于国家对新业态的扶持与就业扩容，像他这样的从业者才得以将零工变为稳 定职业，靠勤劳实现增收。 党的二十届四中全会提出，要切实抓好民生保障，多渠道挖掘潜力，加强稳岗促就业工作，促进重点群 体稳定就业。京东集团外卖全职骑手刘天强对此深有体会。中专毕业后，他辗转于工地与工厂，走南闯 北多年，今年3月正式加入京东外卖，成为深圳首批全职骑手。 "签订正式劳动合同、有五险一金，这比一个月挣3万元还值得开心。如今我看病养老有保障，还能把女 儿接来深圳上学，让孩子接受更好的教育，一家人都能在深圳安居、扎根。"刘天强说。 刘天强感慨道，这些年，骑手的收入越来越高、福利越来越多。大家在每天的奔跑中收获了自信和底 气。越来越多的伙伴选择外卖骑手这个新职业，干得越来越稳定。大伙对骑手这份工作有了更多责任感 和使命感，跑得更有劲、更幸福。 （文章来源：经济日报） ...

Core Viewpoint - The 20th Central Committee of the Communist Party of China emphasizes promoting high-quality development in the real estate sector, indicating a shift towards better housing quality and urban renewal during the 14th Five-Year Plan period [1][2]. Group 1: Real Estate Market Adjustments - The current real estate market in China is still in an adjustment phase, with a focus on achieving higher living standards during the 14th Five-Year Plan [1]. - The development of the real estate industry will center around creating "good houses" and urban renewal, with new supply generating new demand [1]. Group 2: Risk Management and Regulation - The real estate industry must prioritize risk prevention, enhancing regulation throughout the entire process of entry, construction, operation, and exit [1]. - A coordinated financing mechanism for urban real estate will be established, along with a "white list" system for projects to ensure the delivery of commodity housing [1]. Group 3: Service Enhancement in Real Estate - Future real estate development should focus on lifecycle services rather than just construction, emphasizing the importance of both hardware and service quality [2]. - The property service sector is seen as having significant growth potential, which has been largely underestimated, and efforts should be made to improve service levels in areas such as elderly care, childcare, and household services [2].

中国成为跨国企业研发热土 今年以来，一大批外资在华研发项目陆续落地，凸显出越来越多跨国企业正顺应中国经济转型升级大 势，加大在华研发投入，持续提升本地化创新能力，在赢得更广阔市场机遇的同时，也推动中国加速 从"制造基地"向"研发热土"转变。 外资研发布局不断提速 2025年1月至8月，全国新设立外商投资企业42435家，同比增长14.8%。一系列数据表明，外资在华投 资热情不减、投资结构优化。 重视研发、创新导向是高技术产业的重要特征。在此背景下，外资企业在华研发投入力度持续提升，设 立研发中心的步伐明显加快。 商务部研究院发布的《跨国公司在中国》报告提出，2013年后的10年间，在华规模以上外资工业企业研 发经费增长超过86.5%。数据显示，截至目前，上海外资研发中心累计突破600家，北京外资研发中心 数量较去年翻番。 近年来，汉高多次在中国投资研发创新项目。2024年1月，汉高消费品亚洲研发中心正式启用，这是汉 高消费品牌在亚洲最大的研发中心；今年5月，汉高粘合剂上海应用技术中心正式投用；今年9月，总投 资约5亿元的汉高粘合剂技术上海创新体验中心启用。 在医药领域，也有不少跨国企业将中国视为重要创新基地。 ...

Core Insights - The rapid expansion of discount snack stores in China is driven by their ability to cater to consumer behavior and preferences, particularly in lower-tier markets [1][2] - These stores utilize a direct sourcing model to reduce costs and offer a mix of well-known brands and private label products, creating a competitive edge against traditional supermarkets [1][3] Group 1: Market Dynamics - The number of discount snack stores in China is projected to exceed 45,000 by 2025, indicating a significant growth trend since 2022 [1] - Discount snack stores are characterized by a relaxed shopping environment and a diverse range of products, appealing to consumers' non-purposeful shopping habits [1][2] - The stores attract various consumer segments, including children and price-sensitive groups, through targeted product offerings and promotional strategies [2] Group 2: Business Model and Strategy - Discount snack stores have adopted a direct-to-manufacturer supply chain model, which lowers procurement costs and enhances bargaining power [1][3] - The marketing strategy includes frequent promotions and a focus on products that provide immediate gratification, which resonates well with families and budget-conscious consumers [2] - The franchise model is being rapidly adopted by leading brands to scale operations and prepare for potential IPOs, although challenges such as market saturation and profitability remain [3] Group 3: Industry Trends - The industry is entering a phase of consolidation, with larger brands acquiring regional players and diversifying into hybrid business models like "snacks + beverages" [3] - There is an increasing need for consumers to be vigilant about product quality, especially with private label items, as the market becomes more competitive [3] - To sustain growth, discount snack stores must focus on improving product quality, enhancing customer service, and protecting consumer rights [3]

Core Insights - The rapid expansion of discount snack stores in China is driven by their ability to cater to consumer behavior and preferences, particularly in lower-tier markets [1][2] - These stores utilize a direct sourcing model to reduce costs and offer a mix of well-known brands and private label products, creating a competitive edge against traditional supermarkets [2][3] - The franchise model adopted by leading discount snack brands aims to accelerate growth and prepare for potential IPOs, although it faces challenges such as market saturation and profitability concerns [3] Group 1: Market Dynamics - Discount snack stores have seen explosive growth since 2022, with projections indicating over 45,000 stores by 2025 [1] - The stores create a relaxed shopping environment that appeals to consumers' non-purposeful buying habits, enhancing the overall shopping experience [1] - Consumer preferences vary, with urban customers willing to pay for trendy snacks while rural customers favor low-cost bulk items, indicating a broad market potential [1] Group 2: Competitive Strategies - By bypassing traditional supply chains, discount snack stores can negotiate better prices and offer a wider variety of products, including both popular brands and private labels [2] - Targeted marketing strategies focus on family-friendly products and promotions that attract children and budget-conscious consumers, solidifying their market position [2] - Sales tactics such as high-frequency coupons and limited-time offers are employed to engage various consumer demographics, including seniors and students [2] Group 3: Expansion and Challenges - Leading brands are adopting a rapid franchise model to scale operations quickly, promoting low entry costs and support for new franchisees [3] - The simplified approval process for opening new stores attracts investors looking for quick returns, although this model may lead to challenges in maintaining quality and differentiation [3] - As the industry matures, consolidation and the emergence of hybrid business models, such as snack and beverage combinations, are becoming more common [3]

Core Insights - China's foreign trade shows a clear trend of resilience and quality improvement, with a total import and export value of 33.61 trillion yuan in the first three quarters, marking a 4% year-on-year increase [1] - The growth rate of imports and exports has accelerated each quarter, reaching 6% in the third quarter, indicating a strong recovery in foreign trade [1] Group 1: Resilience in Trade - The month of September saw a record monthly growth rate of 8% in foreign trade, reflecting the robust pressure resistance of China's trade sector [1] - The number of active foreign trade entities reached 700,000 in the first three quarters, surpassing the total for the previous year, with 613,000 being private enterprises, highlighting their role as a driving force in foreign trade [1] - China's trade diversification strategies have effectively mitigated external market risks, with high-quality supply from foreign trade enterprises injecting new momentum into exports [1] Group 2: Quality and Efficiency Upgrade - The export scale of industrial robots surged by 54.9% in the first three quarters, showcasing the growing international demand for Chinese manufacturing products [2] - The export of wind turbine generators and parts increased by 23.9%, while popular domestic products like blind box figurines gained traction in over 200 countries and regions [2] - The shift from individual products to comprehensive solutions in manufacturing is evident, with innovations such as smart systems integrating Bluetooth, Beidou, and 5G technology [2] Group 3: Upcoming Events and Market Trends - The upcoming China International Import Expo (CIIE) will feature six major exhibition areas, showcasing cutting-edge achievements in low-altitude economy, new materials, and smart healthcare, aligning with the structural changes in foreign trade [3] - High-tech product exports grew by 11.9%, while imports saw a slight decline of 0.2%, indicating a recovering domestic demand for high-end goods and technologies [3] - The dual circulation model of domestic and international markets is becoming more robust, although challenges such as global economic recovery and trade barriers remain [3]

10月20日至23日，中国共产党第二十届中央委员会第四次全体会议在北京举行，审议通过《中共中央关 于制定国民经济和社会发展第十五个五年规划的建议》。习近平总书记就《建议（讨论稿）》向全会作 了说明。 连日来，国际社会高度关注这次会议。多国人士在接受新华社记者采访时表示，中共二十届四中全会擘 画了中国未来五年的发展蓝图，释放出中国与世界各国共享机遇、共同发展的强烈信号，为变乱交织的 世界注入确定性和正能量。 展现战略定力与长远眼光 "中国能够保持稳定与前进，关键在于政策的延续性、治理的高效性以及社会的强大韧性。"佩雷拉说， 面对复杂多变的外部环境，中国共产党展现出战略定力与长远眼光，持续推动创新驱动、数字化转型和 绿色发展。 全会公报指出，"十五五"时期是基本实现社会主义现代化夯实基础、全面发力的关键时期，在基本实现 社会主义现代化进程中具有承前启后的重要地位。 埃及新闻总署前副署长艾哈迈德·萨拉姆说，当前，全球经济增速放缓，不确定性增多。"在此背景 下，'十五五'规划建议不仅是一份中国的经济社会发展文件，更是一张具有全球意义的发展蓝图。作为 世界第二大经济体和全球经济增长的重要引擎，中国这一规划建议将在稳定和 ...

光天化日之下，仅仅7分钟，8件珍宝被盗，窃贼则全身而退——这并非电影桥段，而是10月19日发生在 法国卢浮宫的盗窃案。 消息传出，举世震惊。无数人感慨，作为世界上最著名的博物馆之一，卢浮宫的防盗系统竟然是"脆 皮"的！ 事实上，自卢浮宫向公众开放以来，安全焦虑从未远离。 1911年8月21日闭馆后，卢浮宫镇馆之宝——名画《蒙娜丽莎》失踪，仅剩4枚钉子残留在墙面。警方调 查后发现，盗窃者是一名意大利工匠，他将画作藏进工作服中，从容带离现场。虽然经过调查与外交交 涉，《蒙娜丽莎》最终回归卢浮宫，但这起事件仍令管理层颜面尽失。 此后百年间，《蒙娜丽莎》又多次遭遇歹人的破坏企图，每次事故都促使卢浮宫加强保护。如今，画作 被安放在防弹玻璃后，又以栏杆隔离。 其实，存在安保隐患的岂止卢浮宫？全球许多博物馆或多或少都面临类似困境。究其原因，缺钱是一个 关键因素。 建设高质量安保体系并非易事——无论是训练有素的安防团队，还是红外探测、电子门禁、加密锁系统 等现代设备，皆需高额投入。博物馆要在"让更多人欣赏艺术"与"保障运营和安保经费"之间求得平衡， 实属艰难。 大英博物馆算是博物馆中比较富裕的一个。其约七成的经费来自政府拨款 ...