Investment Rating - The report maintains a "Buy" rating for the company [4][3]. Core Insights - The company achieved a revenue of 9.11 billion RMB in 2024, representing a year-on-year growth of 16.5%. The gross profit reached 7.83 billion RMB, up 17.9%, while the net profit attributable to shareholders was 2.09 billion RMB, reflecting a growth of 34.9% [1]. - Key products showed robust growth, with sales of the core product, Tebiou, reaching 5.06 billion RMB, a 20.4% increase. The approval of Tebiou for pediatric ITP in April 2024 and the acceptance of its application for chronic liver disease-related thrombocytopenia in August 2024 are expected to drive further growth [1][2]. - The company has a strong innovation pipeline with 30 products under development, focusing on nephrology, hematology, oncology, and other therapeutic areas. Notable approvals in 2024 include the launch of the Minoxidil foam and the approval of other products like Eltrombopag and Apixaban [2]. - Collaborative efforts have expanded the commercial landscape, with four partnerships established in 2024, enhancing the product portfolio and potential sales synergies [2]. Financial Projections - The company is projected to achieve total revenues of 10.49 billion RMB, 12.13 billion RMB, and 14.11 billion RMB for 2025, 2026, and 2027, respectively, with growth rates of 15.2%, 15.7%, and 16.3% [3][6]. - Net profit attributable to shareholders is expected to be 2.54 billion RMB, 2.96 billion RMB, and 3.49 billion RMB for the same years, with growth rates of 21.5%, 16.7%, and 17.7% [3][6]. - The report indicates a corresponding price-to-earnings ratio (P/E) of 10, 9, and 8 for the years 2025, 2026, and 2027 [3].

Group 1 - The Hang Seng Healthcare Index (HSHCI) has seen a strong increase of 1.80%, with notable gains from companies such as Lepu Biopharma-B (up 16.56%) and Zai Lab (up 10.27%) [1] - The Hang Seng Medical ETF (513060) has risen by 2.11%, marking its third consecutive increase, with a trading volume of 4.69 billion yuan [1][2] - The second Boao Lecheng Stem Cell Conference has opened, marking a new phase of standardized and high-quality development in China's stem cell industry [2] Group 2 - Financial analysts predict that the approval and implementation of more projects in the stem cell sector will lead to advanced treatment methods benefiting the public [2] - The domestic medical innovation industry is expected to experience multiple growth opportunities, particularly for companies with true innovation capabilities in new drug development [2] - The Hang Seng Medical ETF has seen a significant growth in scale, increasing by 34.09 billion yuan over the past year, ranking in the top third among comparable funds [2] Group 3 - Since its inception, the Hang Seng Medical ETF has achieved a maximum monthly return of 28.34% and an average monthly return of 7.00% [3] - The ETF has outperformed its benchmark with an annualized excess return of 2.02% over the past year [3] - The ETF's management fee is 0.50%, and the custody fee is 0.15% [3] Group 4 - The tracking error of the Hang Seng Medical ETF is 0.033%, the highest tracking precision among comparable funds [4] - The latest price-to-earnings ratio (PE-TTM) of the Hang Seng Medical Healthcare Index is 24.97, indicating it is at a historical low compared to the past year [4] - The top ten weighted stocks in the Hang Seng Medical Healthcare Index account for 55.64% of the index, with companies like WuXi Biologics and BeiGene among the leaders [4][6]

Investment Rating - The report maintains a "Buy" rating for the company [4][3]. Core Insights - The company achieved a revenue of 9.11 billion RMB in 2024, representing a year-on-year growth of 16.5%. The gross profit reached 7.83 billion RMB, up 17.9%, while the net profit attributable to shareholders was 2.09 billion RMB, reflecting a growth of 34.9% [1]. - Key products showed robust growth, with sales of the core product, Tebiou, reaching 5.06 billion RMB, a 20.4% increase year-on-year. The approval of Tebiou for pediatric ITP in April 2024 and the acceptance of its application for chronic liver disease-related thrombocytopenia in August 2024 are expected to drive further growth [1][2]. - The company has a strong innovation pipeline with 30 products under development, focusing on nephrology, hematology, oncology, autoimmune/ophthalmology, and dermatology/weight loss. Notable approvals in 2024 include the launch of the Minoxidil foam and the approval of Acetylcysteine and Apustel tablets [2]. - Collaborative efforts have expanded the commercial landscape, with four partnerships established in 2024, enhancing the product portfolio and potential sales synergies [2]. Financial Projections - The company is projected to achieve total revenues of 10.49 billion RMB, 12.13 billion RMB, and 14.11 billion RMB for 2025, 2026, and 2027, respectively, with growth rates of 15.2%, 15.7%, and 16.3% [3]. - Net profit attributable to shareholders is expected to be 2.54 billion RMB, 2.96 billion RMB, and 3.49 billion RMB for the same years, with growth rates of 21.5%, 16.7%, and 17.7% [3]. - The report indicates a corresponding price-to-earnings ratio (P/E) of 10, 9, and 8 for the years 2025, 2026, and 2027 [3].

Investment Rating - The report assigns a "Buy" rating for the company, marking its first coverage [6]. Core Insights - The company has over 40 listed products across various therapeutic areas, with core products like TPIAO and Mandi series expected to maintain steady growth. The research pipeline is rich, with several innovative drugs entering harvest periods, particularly SSGJ707 showing promising early clinical results [6][13]. - The company is well-positioned in the market with a diversified business layout and mature commercialization capabilities, driving stable growth of core products [7]. - Financial projections indicate a net profit of 2.33 billion, 2.61 billion, and 2.94 billion CNY for 2025, 2026, and 2027 respectively, with corresponding EPS of 0.97, 1.09, and 1.23 CNY, suggesting a favorable valuation [9]. Summary by Sections 1. Core Products and Innovation Pipeline - The company has a strong focus on innovative drug development, with SSGJ707 (a PD-1/VEGF dual antibody) showing excellent early clinical data and potential for significant market impact [8][24]. - TPIAO, the company's flagship product, is the only commercialized rhTPO globally, with plans to expand its indications, including a recent approval for pediatric ITP [28][34]. 2. Financial Performance and Projections - The company reported a revenue of 9.11 billion CNY in 2024, reflecting a year-on-year growth of 16.5%. The net profit for the same year was approximately 2.09 billion CNY [9][21]. - The gross margin has been stable, with an increase from 80.98% in 2020 to 85.94% in 2024, indicating effective cost management [21]. 3. Market Position and Competitive Landscape - TPIAO has a market share of 66.6% in 2024, benefiting from its safety and efficacy profile, which allows it to replace traditional therapies [40][41]. - The company is actively collaborating with various pharmaceutical firms to enhance its product offerings and market reach, particularly in the oncology and hematology sectors [7][8]. 4. Research and Development Focus - The company has a comprehensive pipeline with 30 products under development, focusing on hematology, oncology, and autoimmune diseases, with several nearing NDA submission [25][24]. - The R&D expenses for 2024 were approximately 1.33 billion CNY, reflecting a commitment to innovation and development of high-value products [21].

Investment Rating - The report assigns a "Buy" rating for the company, marking its first coverage [6]. Core Insights - The company has over 40 listed products across various therapeutic areas, with core products like TPIAO and Mandi series expected to maintain steady growth. The research pipeline is rich, with several innovative drugs entering harvest periods, particularly SSGJ707 showing promising early clinical results [6][13]. - The company is well-positioned in the market with a diversified business layout and mature commercialization capabilities, driving stable growth of core products [7]. - Financial projections estimate the company's net profit for 2025-2027 to be 2.328 billion, 2.612 billion, and 2.938 billion CNY, with corresponding EPS of 0.97, 1.09, and 1.23 CNY, indicating a favorable valuation trend [9]. Summary by Sections 1. Core Products and Innovation - The company has a strong portfolio with TPIAO as its leading product, projected to achieve a 20.4% year-on-year growth in 2024. The successful negotiation for continued pricing and the addition of new indications for TPIAO are expected to provide new growth opportunities [7][40]. - Mandi, the first OTC minoxidil in China, is anticipated to continue its growth trajectory, with revenue reaching 1.337 billion CNY in 2024 [7]. 2. Research and Development Pipeline - The company has a robust pipeline with 30 products under development, focusing on hematology, oncology, and autoimmune diseases. SSGJ707 has shown excellent early clinical data and is expected to be a significant product [8][24]. - The NDA for SSS06, a new generation long-acting erythropoietin, has been accepted, and several other products are in various clinical stages, indicating a strong potential for future revenue growth [8][25]. 3. Financial Performance and Projections - The company reported a revenue of 7.836 billion CNY in 2023, with a projected increase to 10.078 billion CNY in 2025, reflecting a compound annual growth rate of 10.7% [9]. - The gross margin is expected to remain stable around 84.2% for the next few years, with net profit margins improving to 26.6% by 2025 [9][21]. 4. Market Position and Competitive Landscape - TPIAO is the only commercialized rhTPO globally, with expanding indications and a significant market share of 66.6% in 2024. The product's safety and efficacy advantages position it favorably against competitors [34][40]. - The company has established collaborations with various pharmaceutical firms, enhancing its market presence and potential for revenue growth [7].

Group 1 - The Hong Kong technology sector is experiencing a rebound, with the Hong Kong Technology ETF (513560) rising over 1% and a trading turnover rate exceeding 67% [1] - The CSI Hong Kong Stock Connect Technology Index (931573) has increased by 1.19%, with notable gains from companies such as 3SBio (01530) up 11.50% and Li Auto (09863) up 5.37% [1] - The Hong Kong Technology ETF has shown a strong performance over the past year, with a 77.10% increase and a year-to-date rise of 31.42% [1] Group 2 - DeepSeek, a Chinese AI startup, has launched a new version of its model, DeepSeek-V3, which has 685 billion parameters and has significantly improved its capabilities in coding, mathematics, and reasoning [2] - The "catfish effect" from DeepSeek is expected to drive a wave of AI model applications across various industries, particularly in sectors with high digitalization [2] - China's manufacturing sector, especially in discrete manufacturing and process industries, is well-positioned for rapid AI application due to its high level of digitalization [2] Group 3 - Huatai Securities anticipates potential market volatility in April due to tariff issues and economic data releases, but remains optimistic about the long-term growth of AI technology [3] - The report suggests a "barbell strategy" for investment, focusing on Hong Kong internet and tech hardware stocks, new consumption sectors benefiting from stimulus policies, innovative pharmaceuticals related to AI, and stable dividend stocks [3] - The Hong Kong Technology ETF closely tracks the CSI Hong Kong Stock Connect Technology Index, which includes major tech companies like Xiaomi, Alibaba, and Tencent, representing 72.15% of the top ten holdings [3]

Group 1 - The core viewpoint of the articles highlights the positive impact of government policies on the pharmaceutical industry, particularly benefiting companies like Sanofi Pharmaceutical, which saw a stock increase of over 10% following the release of its annual performance report [1][2] - Sanofi Pharmaceutical reported a revenue of 9.108 billion yuan for the year ending December 31, 2024, representing a year-on-year increase of 16.5%, with a net profit attributable to shareholders of 2.09 billion yuan, up 34.9% [2] - The State Council issued an opinion aimed at enhancing the quality of traditional Chinese medicine (TCM) and promoting its high-quality development, outlining 21 key initiatives across eight areas [2] Group 2 - The investment outlook for the TCM sector in 2025 is optimistic, focusing on three main themes: state-owned enterprise reform, innovation in TCM drugs, and the introduction of a basic drug catalog [3] - The Hang Seng Medical ETF has seen significant growth, with an increase of 2.405 billion yuan in scale over the past six months, ranking in the top third among comparable funds [3] - The ETF's performance metrics include a maximum monthly return of 28.34% since inception and a year-to-date maximum drawdown of 6.06%, indicating strong performance relative to benchmarks [4] Group 3 - The Hang Seng Medical Healthcare Index currently has a price-to-earnings ratio (PE-TTM) of 24.39, which is below 99.64% of its historical values, suggesting it is undervalued [5] - The top ten weighted stocks in the Hang Seng Medical Healthcare Index account for 55.2% of the index, with notable companies including WuXi Biologics and BeiGene [5][6] - The ETF's management fee is 0.50%, and its tracking error is 0.032%, indicating high tracking precision compared to similar funds [4]

| 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完整性亦不發表任何聲明，並明確表示，概不對因 | | | --- | --- | | 公告全部或任何部份內容而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 | | | 股票發行人現金股息公告 | | | 發行人名稱 | 三生制药 | | 股份代號 | 01530 | | 多櫃檯股份代號及貨幣 | 不適用 | | 相關股份代號及名稱 | 不適用 | | 公告標題 | 截至2024年12月31日止年度之末期股息 | | 公告日期 | 2025年3月25日 | | 公告狀態 | 新公告 | | 股息信息 | | | 股息類型 | 末期 | | 股息性質 | 普通股息 | | 財政年末 | 2024年12月31日 | | 宣派股息的報告期末 | 2024年12月31日 | | 宣派股息 | 每 股 0.25 HKD | | 股東批准日期 | 2025年6月25日 | | 香港過戶登記處相關信息 | | | 派息金額及公司預設派發貨幣 | 每 股 0.25 HKD | | 匯率 | 1 HKD : 1 HKD | | 除淨日 ...

Financial Performance - Revenue increased by RMB 1,292.1 million or 16.5% to RMB 9,108.0 million[2] - Gross profit rose by RMB 1,186.8 million or 17.9% to RMB 7,828.4 million, with a gross margin of 86.0%[2] - Net profit attributable to equity holders increased by RMB 541.1 million or 34.9% to RMB 2,090.3 million[2] - Adjusted operating profit increased by RMB 366.4 million or 18.8% to RMB 2,318.8 million[2] - EBITDA rose by RMB 784.7 million or 32.8% to RMB 3,173.8 million[2] - Adjusted operating EBITDA increased by RMB 633.9 million or 22.9% to RMB 3,402.3 million[2] - Total comprehensive income for the year was RMB 2,217.5 million, compared to RMB 1,586.3 million in the previous year[4] - The company reported a net profit of RMB 2,217,549, an increase from RMB 1,586,292 in the previous year, representing a growth of approximately 39.8%[5] - Total comprehensive income for the year reached RMB 2,285,205, compared to RMB 1,484,965 in the prior year, indicating a year-over-year increase of about 53.8%[5] Assets and Liabilities - Non-current assets totaled RMB 14,865,806, up from RMB 14,432,345 in the previous year, reflecting an increase of approximately 3%[7] - Current assets increased to RMB 9,346,934 from RMB 9,192,683, marking a growth of about 1.7%[7] - The company's cash and cash equivalents stood at RMB 2,142,651, a decrease from RMB 2,611,161, indicating a decline of approximately 17.9%[7] - Trade receivables rose to RMB 1,305,160, compared to RMB 1,095,132 in the previous year, showing an increase of about 19.2%[7] - Current liabilities increased to RMB 5,463,524 from RMB 3,727,610, representing a significant rise of approximately 46.6%[7] - Non-current liabilities decreased from RMB 3,383,818 thousand in 2023 to RMB 712,886 thousand in 2024, a reduction of approximately 78.9%[8] - The net asset value increased from RMB 16,513,600 thousand in 2023 to RMB 18,036,330 thousand in 2024, representing a growth of about 9.2%[8] - The equity attributable to owners of the parent rose from RMB 14,033,771 thousand in 2023 to RMB 15,436,258 thousand in 2024, an increase of approximately 10%[8] Dividends and Shareholder Returns - The board proposed a final dividend of HKD 0.25 per share for the year ended December 31, 2024[2] - The group plans to distribute a final dividend of HKD 0.25 per share for the year ended December 31, 2023, amounting to RMB 545,302 thousand[38] Market and Product Development - The company plans to expand its market presence and invest in new product development to drive future growth[5] - The company introduced new products including Semaglutide injection and Paclitaxel oral solution in 2024, expanding its therapeutic areas[50] - The company maintained a market share of 66.6% in the platelet reduction treatment market in China for its core product, Tevaziv[50] - The company captured 42.0% of the total market share in the rhEPO market in China in 2024[50] Research and Development - The group has a robust R&D platform covering various innovative large and small molecule products, with a focus on antibody discovery and clinical trial management[76] - The group is advancing multiple innovative biopharmaceuticals and small molecule drugs, including SSS06 (NuPIAO) for anemia and CS1003 for advanced liver cancer[77] - The company completed the Phase III clinical trial for NuPIAO (SSS06) for treating anemia in chronic kidney disease patients in January 2024, achieving the primary endpoint[84] Financial Management - The total tax expense for the year was RMB 500,536 thousand, up from RMB 392,167 thousand in 2023, indicating an increase of approximately 27.7%[35] - The effective tax rate for the group for the year ended December 31, 2024, was 18.4%, down from 19.8% in 2023[36] - Total financing costs decreased to RMB 190,846 thousand in 2024 from RMB 212,296 thousand in 2023, reflecting a reduction of about 10.1%[30] Corporate Governance - The group is committed to maintaining high standards of corporate governance to protect shareholder interests and enhance corporate value[135] - The audit committee, consisting of three independent non-executive directors, has reviewed and approved the accounting principles and practices adopted by the group for the reporting period[140] Employee and Operational Costs - Employee benefits expenses totaled RMB 1,564,714 thousand in 2024, compared to RMB 1,362,262 thousand in 2023, marking an increase of about 14.8%[29] - Employee costs, including directors' remuneration (excluding any retirement benefit plan contributions), amounted to approximately RMB 1,469.8 million during the reporting period, compared to approximately RMB 1,271.5 million in the same period last year[131] Compliance and Reporting - The financial statements are prepared in accordance with International Financial Reporting Standards, ensuring compliance and transparency[10] - Ernst & Young has confirmed that the financial information in the preliminary results announcement is consistent with the group's consolidated financial statements[141]

Investment Rating - The report initiates coverage with a "Buy" rating for the company [4]. Core Views - The company is positioned as a leading player in the biopharmaceutical sector, with a strong portfolio of core products and an innovative pipeline that is expected to drive growth [1][13]. - The core products, including Tevaz (rhTPO) and Mandi (Minoxidil), dominate their respective markets, while the innovative pipeline, particularly SSGJ-707 (PD-1/VEGF dual antibody), shows promising clinical data and potential for international collaboration [2][4][14]. Summary by Sections Company Overview - Established in 1993, the company has over 100 national invention patents and more than 40 marketed products across various therapeutic areas, including nephrology, oncology, and autoimmune diseases [13][14]. - The company has a robust R&D infrastructure with four major research centers and a comprehensive CDMO platform [14]. Core Products and Market Position - Tevaz achieved sales of 2.48 billion CNY in H1 2024, capturing 66.2% of the Chinese market for thrombocytopenia treatment [14]. - Mandi holds over 70% market share in the hair loss treatment sector, with innovative product forms enhancing its competitive edge [3][14]. Innovative Pipeline - The innovative pipeline includes SSGJ-707, which has shown excellent clinical data in Phase II trials, and other promising candidates in autoimmune and oncology sectors [4][11]. - The company is actively pursuing international collaborations to expand its product offerings and market reach [2][4]. Financial Projections - The company is expected to see steady revenue growth, with projected revenues of 9.13 billion CNY in 2024 and 10.53 billion CNY in 2025, reflecting growth rates of 16.85% and 15.30% respectively [5]. - Net profit forecasts for 2024, 2025, and 2026 are 2.19 billion CNY, 2.46 billion CNY, and 2.77 billion CNY, indicating a strong recovery and growth trajectory [5][4].