| A | 股代码：688428 | A 股简称：诺诚健华 | 公告编号：2025-035 | | --- | --- | --- | --- | | 港股代码：09969 | | 港股简称：诺诚健华 | | 诺诚健华医药有限公司 关于向激励对象授予预留限制性股票的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： 限制性股票预留授予日：2025 年 8 月 20 日 限制性股票预留授予数量：246.7550 万股，约占目前公司已发行股份总数 176,464.3952 万股的 0.14% 股权激励方式：第二类限制性股票 诺诚健华医药有限公司（以下简称"诺诚健华"或"公司"）《2024 年科创 板限制性股票激励计划（草案）》（以下简称"《激励计划（草案）》"）规定 的公司 2024 年科创板限制性股票激励计划（以下简称"本次激励计划"或"本激 励计划"）的预留授予条件已经成就，根据公司 2024 年第一次临时股东大会（股 东特别大会）的授权，公司于 2025 年 8 月 20 日召开董事会审议通过了《根据 ...

诺诚健华医药有限公司 2024 年科创板限制性股票激励计划预留授予激励对象名单 （截至预留授予日） 一、本激励计划拟授予的限制性股票在各激励对象间的分配情况如下表所示： | 姓名 | 国籍 | 职务 | 获授的限制 | 占授予权益总 | 占本激励计划预留 | | --- | --- | --- | --- | --- | --- | | | | | 性股票数量 | 数的比例 | 授予时已发行股份 | | | | | （万股） | | 总数的比例 | | 一、董事、高级管理人员、核心技术人员 | | | | | | | / | / | / | / | / | / | | 二、其他激励对象 | | | | | | | 董事会认为需要激励的其他员工（91 | | 人） | 246.7550 | 20.00% | 0.14% | | 合计 | | | 246.7550 | 20.00% | 0.14% | 注：1、上述任何一名激励对象通过公司全部有效期内的股权激励计划获授的公司股票数量累计未超过 本激励计划提交股东大会审议时公司已发行股份总数的 1%。公司全部有效期内的股权激励计划所涉及的标 的股票总额未超过本激励计 ...

FANGDA PARTNERS http://www.fangdalaw.com 关于诺诚健华医药有限公司（InnoCare Pharma Limited） 2024 年科创板限制性股票激励计划预留授予相关事项的 法律意见书 邮政编码：200041 传 真 Fax.: +86-21-5298 5599 中国上海市石门一路 288 号 电子邮件 E-mail: email@fangdalaw.com 兴业太古汇香港兴业中心二座 24 楼 电 话 Tel.: +86-21-2208 1166 24/F, HKRI Centre Two HKRI Taikoo Hui 288 Shi Men Yi Road Shanghai, PRC 200041 上海市方达律师事务所 致：诺诚健华医药有限公司（InnoCare Pharma Limited） 上海市方达律师事务所（以下简称"本所"）是具有中华人民共和国境内法律 执业资格的律师事务所。根据诺诚健华医药有限公司（InnoCare Pharma Limited） （以下简称"诺诚健华"、"公司"或"上市公司"）的委托，本所担任诺诚健华 2024 年科创板限制性股票激励 ...

证券代码：688428 证券简称：诺诚健华 港股代码：09969 港股简称：诺诚健华 上海荣正企业咨询服务（集团）股份有限公司 关于 诺诚健华医药有限公司 2024 年科创板限制性股票激励计划预留授予事项 之 独立财务顾问报告 2025 年 8 月 | 一、释义 | 2 | | --- | --- | | 二、声明 | 3 | | 三、基本假设 | 4 | | 四、独立财务顾问意见 | 5 | | 五、备查文件及咨询方式 | 9 | 一、释义 | 本公司、公司、上市公 | 指 | InnoCare Pharma Limited，中文名称：诺诚健华医药有限公 | | --- | --- | --- | | 司 | | 司 | | 独立财务顾问 | 指 | 上海荣正企业咨询服务（集团）股份有限公司 | | 独立财务顾问报告 | 指 | 上海荣正企业咨询服务（集团）股份有限公司关于诺诚健华 | | | | 医药有限公司 2024 年科创板限制性股票激励计划预留授予 | | | | 事项之独立财务顾问报告 | | 本激励计划、本计划 | 指 | 诺诚健华医药有限公司 2024 年科创板限制性股票激励计划 | | 限制 ...

Group 1 - Weicai Technology achieved a net profit of 101 million yuan in the first half of 2025, a year-on-year increase of 831.03% [1] - The company reported an operating income of 634 million yuan, up 47.53% year-on-year, with a basic earnings per share of 0.68 yuan [1] - Weicai Technology specializes in wafer testing, chip finished product testing, and related integrated circuit testing services [1] Group 2 - Changhua Group received a project development notification from a domestic automotive company, with an expected total sales amount of approximately 190 million yuan over an 8-year lifecycle [2] - The project is set to begin mass production in the third quarter of 2026 [2] - Changhua Group focuses on the research, production, and sales of automotive metal components [2][3] Group 3 - Junhe Co. reported a net profit of 30.99 million yuan in the first half of 2025, a year-on-year decrease of 19.53% [3] - The company achieved an operating income of 578 million yuan, up 5.53% year-on-year, with a basic earnings per share of 0.08 yuan [3][4] - Junhe Co. specializes in the research, design, manufacturing, and sales of household water pumps and their accessories [4] Group 4 - Tonghua Jinma reported a net profit of 16.80 million yuan in the first half of 2025, a year-on-year increase of 34.77% [5] - The company achieved an operating income of 650 million yuan, a slight increase of 0.12% year-on-year, with a basic earnings per share of 0.0174 yuan [5] - Tonghua Jinma focuses on the research, production, and sales of pharmaceutical products [5][6] Group 5 - Xing Shuai reported a net profit of 122 million yuan in the first half of 2025, a year-on-year increase of 31.79% [8] - The company achieved an operating income of 1.132 billion yuan, up 8.59% year-on-year, with a basic earnings per share of 0.37 yuan [8] - Xing Shuai specializes in the research, production, and sales of various types of refrigeration compressor thermal protectors, starters, and temperature controllers [8] Group 6 - Ice Wheel Environment reported a net profit of 266 million yuan in the first half of 2025, a year-on-year decrease of 19.71% [9] - The company achieved an operating income of 3.118 billion yuan, down 6.92% year-on-year, with a basic earnings per share of 0.27 yuan [9] - Ice Wheel Environment focuses on the research, design, and sales of artificial environment control technology and energy comprehensive utilization technology [9][10] Group 7 - Jiangsu Huachen reported a net profit of 47.27 million yuan in the first half of 2025, a year-on-year increase of 18.37% [18] - The company achieved an operating income of 938 million yuan, up 40.46% year-on-year, with a basic earnings per share of 0.2901 yuan [18] - Jiangsu Huachen specializes in the research, production, and sales of energy-saving transformers and smart electrical equipment [18] Group 8 - Hanma Technology reported a net profit of 27.73 million yuan in the first half of 2025, reversing from a loss of 153 million yuan in the same period last year [18] - The company achieved an operating income of 2.847 billion yuan, a year-on-year increase of 50.03% [18] - Hanma Technology focuses on the production, research, and sales of heavy trucks, special vehicles, and automotive components [18] Group 9 - Tianyue Advanced announced the listing of its H-shares on the Hong Kong Stock Exchange, raising approximately 1.938 billion HKD [19] - The global offering consisted of 47.7457 million shares, with a price of 42.80 HKD per share [19] - Tianyue Advanced specializes in the research, production, and sales of silicon carbide semiconductor materials [19][20] Group 10 - Kesi Technology signed a sales framework contract worth up to 401 million yuan with Beijing Tianyuan Innovation Technology Co., Ltd. [21] - The contract is valid for two years and involves a comprehensive information integration service project [21] - Kesi Technology focuses on the research, development, manufacturing, and sales of electronic information equipment [21][22]

（文章来源：每日经济新闻） 国金证券8月20日发布研报称，给予诺诚健华（688428.SH，最新价：30.62元）买入评级。评级理由主 要包括：1）加速创新成果兑现，上半年多项里程碑创国内首次纪录；2）国际化进程行稳致远，后续出 海合作潜力可期。风险提示：竞争加剧风险、临床试验结果不及预期风险、临床时间及资金成本超预期 风险、BD不及预期风险、上市进度不及预期风险。 ...

Summary of InnoCare Pharma Earnings Review Company Overview - **Company**: InnoCare Pharma (Ticker: 9969.HK) - **Industry**: Biotechnology Key Financial Highlights - **2Q Revenue**: Rmb350 million, representing a **38% year-over-year increase** [1] - **Orela Sales**: Rmb325 million, a **29% year-over-year increase** compared to guidance of Rmb340 million [1] - **Net Loss**: Narrowed to **Rmb48 million** from **Rmb119 million** in the previous year [1] - **Gross Margin**: Improved to **88.4%** from **85.9%** in 2Q24 [1] - **Collaboration Income**: Rmb25 million contributed to financial performance [1] - **Cash Balance**: Strong cash position of **Rmb7.7 billion** as of 2Q, only slightly lower than the end of 1Q [1] Growth Drivers - **MZL Indication**: Remains the key growth driver for the company [1] - **New Indications**: Newly approved indication for **1L CLL/SLL** expected to drive sales growth in the coming years following NRDL inclusion [1] - **Sales Guidance**: Management maintains a full-year sales growth guidance of **35%+** for 2025, with a high likelihood of exceeding this target based on solid 2Q performance [1] - **New Products**: Potential revenue from newly approved **tafasitamab** and additional business development income anticipated in 2H25 [1] Strategic Initiatives - **Orela Sales Target**: Management targets **US$1 billion** in peak sales for orela, driven by deeper penetration in MZL and potential new indications [2] - **ITP Indication**: Expected to file sNDA in **1H26**, with a market potential of **Rmb1-1.5 billion** [2] - **SLE Treatment**: Plans to change the treatment landscape for SLE with orela as an oral targeted drug [2] - **Commercial Strategy**: Plans to leverage existing hematology franchise for ITP and consider building a separate team for SLE in two years [2] Clinical Development - **Phase 3 Trials**: Plans to start patient enrollment in **2H25** for global phase 3 clinical trials for orela in PPMS and SPMS [3] - **Partnership Strategy**: Management prefers to wait for more validation from preliminary clinical data before licensing out pre-clinical assets [3] - **Clinical Focus**: Shifted focus to global clinical trials for **1L AML and MDS** instead of 1L CLL/SLL for faster development timelines and ROI [3] Earnings Forecast Revision - **Earnings Forecast**: Revised up for 2025E/2026E/2027E by Rmb23 million/Rmb11 million/Rmb11 million to account for higher collaboration income [4] - **Probability of Success (PoS)**: Increased for ITP indication to **80%** from **70%** due to better visibility for sNDA [4] Price Target and Risks - **12-Month Price Target**: HK$20.59 for H-Share and Rmb39.66 for A-Share, reflecting an increase from previous targets [8][9] - **Key Risks**: Include R&D risks for key clinical assets, lack of long-term commercialization track record, pricing uncertainties, potential entry of generic ibrutinib in 2027, and below-expected progress in global expansion [9] Conclusion InnoCare Pharma shows strong growth potential driven by solid sales performance, strategic product development, and a robust financial position. The company is well-positioned to exceed its sales guidance for 2025, with significant opportunities in new indications and collaborations. However, investors should remain cautious of inherent risks associated with R&D and market competition.

Core Viewpoint - Nocera Biotech (09969) experienced a decline of over 4% following the release of its interim results, with shares trading at HKD 19.01 and a transaction volume of HKD 66.54 million [1] Financial Performance - For the six months ending June 30, 2025, Nocera Biotech reported revenue of RMB 731 million, representing a year-on-year increase of 74.26% [1] - The adjusted loss for the period was RMB 15.504 million, a decrease of 93.62% compared to the previous year [1] - The loss attributable to the company's owners was RMB 30.091 million, down 88.51% year-on-year [1] - The loss per share was RMB 0.02 [1] Revenue Drivers - The increase in revenue was primarily driven by strong sales growth of Oubutini and licensing income from Prolium [1] - Revenue from Oubutini rose from RMB 417 million for the six months ending June 30, 2024, to RMB 637 million for the same period in 2025, marking a 52.8% increase due to expanded coverage and an increase in treated patients [1]

Core Viewpoint - The company, Nuo Cheng Jian Hua, experienced a stock decline of over 4% following the release of its interim financial results, despite reporting significant revenue growth and reduced losses [1]. Financial Performance - For the six months ending June 30, 2025, the company reported revenue of RMB 731 million, representing a year-on-year increase of 74.26% [1]. - The adjusted loss for the period was RMB 15.5 million, a decrease of 93.62% compared to the previous year [1]. - The loss attributable to the parent company was RMB 30.1 million, down 88.51% year-on-year [1]. - The earnings per share were reported at a loss of RMB 0.02 [1]. Revenue Drivers - The increase in revenue was primarily driven by strong sales of Obutuzumab and licensing income from Prolium [1]. - Revenue from Obutuzumab rose from RMB 417 million for the six months ending June 30, 2024, to RMB 637 million for the same period in 2025, marking a growth of 52.8% due to an expanded coverage and an increase in treated patients [1].

Core Viewpoint - The company reported strong performance in 1H25, with revenue of 731 million yuan, a year-on-year increase of 74.26%, despite a net loss of 30.09 million yuan, driven by high growth of its core product, Orelabrutinib, and the confirmation of an upfront payment from Prolium for licensing [1][2]. Financial Performance - Revenue for 1H25 reached 731 million yuan, representing a 74.26% year-on-year growth [1]. - The net loss for the period was 30.09 million yuan, indicating a significant narrowing of losses [2]. - Gross margin improved to 89.5%, up 3.8 percentage points year-on-year, primarily due to the rapid growth of Orelabrutinib and the licensing agreement with Prolium [2]. - Sales expenses increased by 55.3% to 244 million yuan, while R&D expenses rose by 5.7% to 450 million yuan [2]. Product Development and Market Expansion - Orelabrutinib sales exceeded expectations, generating 637 million yuan in revenue for 1H25, a 52.8% increase, benefiting from the continued growth of its exclusive indication for MZL [2]. - The company received approval for Tafasitamab for treating DLBCL in May 2025, marking it as the first CD19 monoclonal antibody approved for R/R DLBCL in China [2]. - Orelabrutinib has expanded its indications, receiving a level I recommendation in the CSCO guidelines for 1L CLL/SLL and is set to participate in this year's medical insurance negotiations [2]. - Ongoing global Phase III clinical trials for Orelabrutinib in treating PPMS and SPMS are being initiated, with NDA submission expected in 1H26 for ITP indication [3]. Profit Forecast and Valuation - The company has revised its 2025 loss forecast from 415 million yuan to 319 million yuan and the 2026 forecast from 225 million yuan to 203 million yuan due to better-than-expected sales of Orelabrutinib [4]. - The target prices for A/H shares have been raised by 36.0% and 77.3% to 35.00 yuan and 22.00 HKD, respectively, indicating an upside potential of 10.0% and 10.8% from current prices [4].