Summary of Key Points Core Viewpoint - On May 23, 2025, Zhaoyan New Drug (603127) closed at 17.3 yuan, marking a 2.73% increase with a turnover rate of 6.57% and a trading volume of 414,000 shares, amounting to a transaction value of 718 million yuan [1]. Trading Information - On May 23, 2025, the net outflow of main funds for Zhaoyan New Drug was 9.2293 million yuan, while the net inflow from speculative funds was 4.6736 million yuan, and the net inflow from retail investors was 4.5556 million yuan [2]. Company Announcements - Zhaoyan New Drug announced on May 22, 2025, that its member companies subscribed to four structured deposit products from Jiangsu Bank, with a total investment of 440 million yuan. The company confirmed that all other financial products previously subscribed to Jiangsu Bank have been fully redeemed, and these investments are not expected to adversely affect the financial status of the company [1][2]. Structured Deposit Plans - Zhaoyan (Suzhou) New Drug signed a principal-protected floating return structured deposit plan with Jiangsu Bank for 150 million yuan, with an expected annual return rate of 0.1%-2.45%, starting on November 22, 2024, and maturing on May 22, 2025 [3]. - Zhaoyan Management Technology signed a principal-protected floating return structured deposit plan with Jiangsu Bank for 60 million yuan, with an expected annual return rate of 1.60%-2.50%, starting on December 27, 2024, and maturing on December 27, 2025 [3]. - Zhaoyan Management Technology also signed a principal-protected floating return structured deposit plan with Jiangsu Bank for 200 million yuan, with an expected annual return rate of 1.00%-2.56%, starting on February 26, 2025, and maturing on August 26, 2025 [3]. - Additionally, Zhaoyan (Suzhou) New Drug signed a principal-protected floating return structured deposit plan for 30 million yuan, with an expected annual return rate of 1.50% or 2.45%, starting on May 23, 2025, and maturing on November 23, 2025 [3].

Market Overview - On May 23, the A-share market showed strong performance before noon but retreated in the afternoon, with the Shanghai Composite Index down 0.94% to 3348.37 points, the Shenzhen Component Index down 0.85% to 10132.41 points, and the ChiNext Index down 1.18% to 2021.50 points [2] - The total market turnover was 118.26 billion yuan, an increase of 42.9 billion yuan compared to the previous trading day [2] - Leading sectors included pharmaceuticals, automotive supply chains, and controllable nuclear fusion, while previously popular micro-cap stocks continued to adjust [2] Pharmaceutical Sector - The pharmaceutical sector experienced a strong surge, with leading innovative drug company Heng Rui Pharmaceutical listing on the Hong Kong Stock Exchange and seeing its stock price rise over 25%, boosting the entire innovative drug industry chain [3] - A-share pharmaceutical stocks rose against the trend, with companies like Hai Chen Pharmaceutical and Zhong Sheng Pharmaceutical hitting the daily limit, while Hua Sen Pharmaceutical and Cheng Da Pharmaceutical also saw gains [3] - Multiple innovative drug companies announced they would showcase their research results at the 2025 American Society of Clinical Oncology (ASCO) annual meeting from May 30 to June 3 [3] - The market's expectations for domestic innovative drugs going global were heightened following the news of a dual-antibody new drug licensing collaboration between Sanofi and Pfizer [3] - According to NextPharma, Chinese pharmaceutical companies completed 41 overseas licensing transactions in Q1 2025, totaling 36.9 billion USD, nearing the total for the entire year of 2023 [3] - From 2015 to 2024, China ranked first globally in the cumulative number of original innovative drugs developed [4] - Zhonghang Securities noted that the innovative drug industry is undergoing profound changes, with companies enhancing their core advantages and transitioning from followers to significant players in international competition [3] Micro-Cap Stocks - Micro-cap stocks initially performed well but began to adjust from mid-week, with high-profile stocks like Nanjing Port and Langsha experiencing significant fluctuations [5] - Wangzi New Materials gained attention from active market funds, achieving a limit-up on May 23 and recording five consecutive trading days of gains, effectively doubling in value [5] - According to Founder Securities, the dominance of micro-cap stocks has been a notable feature of the A-share market this year, with strong mean reversion properties observed in small-cap styles [5] - The outlook for the market suggests that the trend favoring micro-cap stocks may continue, supported by factors such as a stable capital market, ongoing economic transformation, and sustained liquidity [5]

Group 1 - The overall market experienced a decline in the afternoon, but the pharmaceutical and medical sectors showed resilience, with only three out of 31 industries reporting gains [1] - The representative medical ETF (512170) saw a daily increase of 0.62%, with a significant trading volume of 9.82 billion, marking a 128% increase from the previous day and the highest single-day trading volume in over a month and a half [2] - The CXO-related stocks were the main contributors to the sector's performance, with notable gains from companies like Tigermed, which rose by 5.64%, while major player WuXi AppTec experienced a decline [2] Group 2 - For the week of May 19-23, the medical ETF (512170) accumulated a gain of 1.24%, outperforming major indices such as the Shanghai Composite Index, which fell by 0.57% [4] - The market for medical stocks is gradually recovering, with increased trading activity and positive catalysts such as domestic pharmaceutical companies securing overseas contracts [4] - A new "Pharmaceutical ETF" is set to launch on May 26, which will track the CSI Pharmaceutical Index, focusing on chemical drugs, biological drugs, and traditional Chinese medicine, complementing the existing medical ETF [4] Group 3 - The medical and pharmaceutical sectors have been in a prolonged adjustment period since 2021, with current valuations potentially offering high cost-effectiveness for investors [4]

Core Viewpoint - The pharmaceutical sector in China is experiencing significant growth, driven by favorable government policies and increasing international market share, with a notable rise in innovative drug development and exports [1][2]. Group 1: Market Performance - On May 23, 2025, pharmaceutical stocks collectively surged, with sectors like Helicobacter pylori, AI healthcare concepts, and weight-loss drugs rising over 2% [1]. - Hai Chen Pharmaceutical's stock hit a 20% limit up within three minutes of opening, reaching a new high in two and a half years [1]. - Heng Rui Pharmaceutical officially listed on the Hong Kong stock market, with its stock price increasing by approximately 30% post-opening, raising about 9.9 billion HKD through an IPO of 224.5 million shares, marking the largest IPO in the Hong Kong pharmaceutical sector in five years [1]. Group 2: Export and Innovation - In Q1 2025, China's pharmaceutical and healthcare product exports reached 26.632 billion USD, a year-on-year increase of 4.39%, while imports decreased by 4.42% to 20.456 billion USD, indicating a domestic industry upgrade and import substitution effect [1][2]. - The United States remains the largest single market for Chinese pharmaceutical exports, with exports amounting to 4.639 billion USD, a 9.6% increase, primarily driven by raw materials and disposable medical supplies [2]. - By the end of 2024, the number of active innovative drugs developed by Chinese companies reached 3,575, ranking first globally, with domestic products accounting for 42% of newly approved innovative drugs, up from less than 10% in 2015 [2]. Group 3: Future Outlook - Analysts predict that 2025 will be a pivotal year for the pharmaceutical industry in China, marking the beginning of significant revenue growth, profitability for many companies, and an extended valuation cycle due to improvements in payment systems [2].

Core Viewpoint - The pharmaceutical sector in Hong Kong and A-shares has experienced a significant surge, driven by the upcoming 2025 American Society of Clinical Oncology (ASCO) annual meeting where multiple innovative drug companies will showcase their research results. The market is optimistic about the potential of Chinese innovative drugs entering the global market, particularly following the collaboration between 3SBio and Pfizer on a PD-1/VEGF dual antibody [1][3][6]. Group 1: Market Performance - The Hong Kong pharmaceutical sector saw a broad rally, with the Hang Seng Healthcare Index rising over 2%. Notable stock performances included a more than 15% increase for Haijia Medical and over 11% for Green Leaf Pharmaceutical [2]. - In the A-share market, the innovative drug sector also performed strongly, with Haichen Pharmaceutical hitting a 20% limit up and multiple companies like Zhongsheng Pharmaceutical and Huason Pharmaceutical also reaching their limits [3]. Group 2: ASCO Annual Meeting Highlights - Several companies announced their participation in the ASCO annual meeting, including: 1. BeiGene will present 23 abstracts focusing on new data for its product portfolio in hematological and solid tumor treatments [3]. 2. Kelun-Biotech will share results from six clinical studies, including data on its ADC and PD-L1 monoclonal antibody [4]. 3. Ascentage Pharma will present the latest clinical data on APG-2575 and APG-115 [4]. 4. Legend Biotech will disclose updates on its CARVYKTI clinical development project for multiple myeloma [4]. 5. Hengrui Medicine will present updated data on several of its compounds [4]. Group 3: Future Outlook - Analysts predict that 2025 will mark a pivotal year for the pharmaceutical industry, characterized as the "three milestone years": a year of revenue growth post-medical insurance negotiations, a year of profitability for many companies, and a year of valuation uplift due to improved payment conditions [6]. - The Chinese innovative drug sector is transitioning from being followers to becoming significant players in the international market, with a notable increase in the number of innovative drugs developed by Chinese companies, reaching 3,575 by the end of 2024, surpassing the U.S. [6]. Group 4: Investment Recommendations - Analysts recommend focusing on Hong Kong innovative drug stocks due to several factors: 1. The potential for excess returns as companies establish global competitive advantages [7]. 2. The increasing global competitiveness of Chinese innovative drugs, particularly through licensing agreements [7]. 3. Favorable policy and regulatory changes that support the sector [7]. 4. Financial performance indicators show steady revenue growth and relatively safe valuation levels compared to other growth sectors [7].

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香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 須予披露交易 進一步認購金融產品 進一步認購金融產品 團 的 財 務 狀 況 造 成 任 何 不 利 影 響。 上市規則的涵義 在 認 購 第 四 項 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品 之 前，由 於 根 據 上 市 規 則 第 構 性 存 款 產 品 及 第 三 項 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品 計 算（無 論 是 單 獨 計 董 事 會 謹 此 公 佈，於 2025 年 5 月 22 日（交 易 時 間 後），本 集 團 成 員 公 司 剛 認 購 且 於本公告日期仍未到期的該等江蘇 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 須予披露交易 進一步認購金融產品 進一步認購金融產品 董 事 會 謹 此 公 佈，於2025年5月22日（交 易 時 間 後），本 集 團 成 員 公 司 剛 認 購 且 於本公告日期仍未到期的該等江蘇銀行人民幣結構性存款產品合計投資總 額分別為人民幣440,000,000元。 在 認 購 第 四 項 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品 之 前，由 於 根 據 上 市 規 則 第 14.07條 就 首 項 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品、第 二 項 江 蘇 銀 行 人 民 幣 結 構性存款產 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 須予披露交易 進一步認購金融產品 然 而，在 認 購 第 四 項 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品 之 後，由 於 根 據 上 市 規 則 第14.07條就認購該等江蘇銀行人民幣結構性存款產品而按合併基準計算 的最高適用百分比率高於5%但低於25%，根 據 上 市 規 則 第14章，認 購 該 等 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品 將 構 成 本 公 司 的 一 項 須 予 披 露 交 易，因 此 須 遵守上市規則第14.34條 所 載 的 通 知 及 公 告 規 定。 進一步認購金融產品 ...

昭衍新药于2025年5月13日发布公告，披露关于回购注销部分限制性股票并通知债权人相关事宜。 因激励对象变动触发回购注销 公司于2023年3月30日召开的第四届董事会第二次会议，审议通过了《关于回购注销2019年股票期权与 限制性股票激励计划部分限制性股票的议案》《关于回购注销2021年A股限制性股票激励计划部分限制 性股票的议案》；2023年4月27日召开的第四届董事会第三次会议，再次审议通过《关于回购注销2021 年A股限制性股票激励计划部分限制性股票的议案》。 根据公司《2019年股票期权与限制性股票激励计划（草案）》和《股权激励计划实施考核管理办法》， 1名激励对象因个人原因离职，不符合股权激励计划规定，董事会决定回购注销其持有的限制性股票 0.3293万股。 依据《2021年A股限制性股票激励计划（草案）》和相关考核管理办法，21名激励对象因个人原因离职 或个人业绩考核结果不达标，不符合激励对象规定，董事会决定回购注销其持有的限制性股票3.1108万 股。 2025年1月23日，公司召开2025年第一次临时股东大会，审议通过《关于公司变更注册资本的议案》。 上述回购注销完成后，公司总股本将由535, ...