Investment Rating - The report maintains an investment rating of "Outperform" with a rating of A [7] Core Insights - The report highlights significant advancements in small nucleic acid drugs for the treatment of hepatitis B, particularly the promising data from the drug AHB-137 presented at the AASLD 2025 conference, indicating its potential as the best small nucleic acid drug for hepatitis B [3][22] Summary by Sections Weekly New Drug Market Review - From November 17 to November 23, 2025, the top five gainers in the new drug sector were: - LaiKai Pharmaceutical (+13.34%) - Beihai Kangcheng (+2.67%) - Jiahe Biotech (+2.19%) - Yongtai Biotech (+1.94%) - Youzhi You (+1.14%) - The top five losers were: - WuXi AppTec (-15.75%) - Adi Pharma (-14.56%) - Mengke Pharma (-14.34%) - Yiming Oncology (-13.40%) - Kain Technology (-13.04%) [1][16] Weekly Focused Investment Targets - The report suggests focusing on several promising targets due to upcoming catalysts, including: 1. Products with high certainty for overseas expansion certified by MNCs: Sanofi, Federated Pharmaceuticals, and Kelun-Botai 2. Products with overseas data catalysts: Betta Pharmaceuticals, Hutchison China MediTech, and Yiming Biotech 3. Potential blockbuster products for overseas licensing by MNCs: Fuhong Hanlin, CSPC Pharmaceutical Group, and Yifang Biotech 4. New innovative drug technology breakthroughs: small nucleic acids, in vivo CAR-T, fat reduction and muscle gain, autoimmune CAR-T/bispecific antibodies, and gene therapy [2][20] Weekly New Drug Industry Analysis - The report emphasizes the breakthrough data for small nucleic acid drugs in treating hepatitis B, particularly the two-phase follow-up data for AHB-137, which shows a high potential for becoming the leading small nucleic acid drug in this field [3][22] Weekly New Drug Approval & Acceptance Status - No new drug or new indication approvals were reported this week, but six new drug or new indication applications were accepted [4][24] Weekly New Drug Clinical Application Approval & Acceptance Status - This week, 42 new drug clinical applications were approved, and 44 new drug clinical applications were accepted [5][26] Domestic Market Key Events TOP3 - Key events included: 1. Zean Biopharma's strategic collaboration with GSK to develop up to four "first-in-class" candidates in oncology [11] 2. Innovent Biologics announcing successful Phase III clinical study results for a drug in moderate to severe obesity [11] 3. Fuhong Hanlin's FDA approval for a biosimilar product [11] Overseas Market Key Events TOP3 - Key events included: 1. Merck's presentation of key Phase III trial results at the AHA Scientific Sessions [12] 2. Johnson & Johnson's acquisition of Halda Therapeutics for $3.05 billion [12] 3. The EMA's recommendation for the approval of a gene therapy product [12]

- The report does not contain any quantitative models or factors, nor does it provide any related construction processes, formulas, or backtesting results[1][7][8]

Investment Rating - The report maintains an investment rating of "Outperform the Market - A" for the industry [5] Core Insights - The epoxy active diluents are expected to see sustained demand growth due to their excellent properties and wide applications, particularly in composite materials, coatings, electronics, and adhesives [2] - The recent fire incident at XinYuan Technology, the largest global producer of epoxy active diluents, may lead to a temporary shortage in supply, impacting the global market [3] - Price increases have been observed in the market due to supply tightness, with significant price hikes reported for various active diluents [4] Summary by Sections - **Industry Overview**: The global consumption of epoxy active diluents was approximately 228,000 tons in 2021, with significant demand from composite materials (32%), coatings (16%), and electronics (15%) [2] - **Market Dynamics**: The rapid growth of wind power installations in China is expected to drive demand for epoxy active diluents, with a projected increase of 51.39 GW in new installations in the first half of 2025, a year-on-year increase of 99% [2] - **Supply Chain Impact**: XinYuan Technology has a production capacity of 50,000 tons and accounted for 20% of the global market share in 2021. The fire incident may disrupt supply chains and lead to a temporary shortage [3] - **Price Trends**: Recent market conditions have led to significant price increases for epoxy active diluents, with reported price hikes of 18%, 16%, and 24% for different products as of November 21 [4] - **Investment Opportunities**: Companies such as Kangda New Materials and Huangma Technology are highlighted as potential investment opportunities due to their production capacities in epoxy resin diluents [11]

Investment Rating - The report maintains an investment rating of "Outperform the Market - A" for the chemical industry [5]. Core Insights - The report emphasizes the potential price increases for epoxy active diluents and organic silicon due to supply constraints and rising demand in various applications [2][3]. - A significant fire incident at a major producer of epoxy active diluents may lead to a temporary global shortage, prompting price hikes in the market [3]. - The report highlights the ongoing recovery in the chemical sector, driven by improved supply-demand dynamics and strategic industry collaborations to stabilize prices [10][11]. Summary by Sections 1. Core Views of the Week - The epoxy active diluents market is expected to see sustained demand growth, particularly from the wind energy sector, with China's new wind power installations projected to reach 51.39 GW in the first half of 2025, a year-on-year increase of 99% [2]. - The organic silicon industry is experiencing a price rebound due to coordinated production cuts and price increases, with prices rising to 13,100 yuan/ton, reflecting a 2,000 yuan/ton increase since the announcement of price stabilization efforts [10][11]. 2. Chemical Sector Performance - The chemical sector index has shown a decline of 7.5% in the past week, underperforming compared to the broader market indices [24]. - Year-to-date, the chemical sector index has increased by 23.9%, outperforming the Shanghai Composite Index by 9.5% [24]. 3. Investment Opportunities - The report suggests focusing on companies involved in the production of epoxy active diluents and organic silicon, such as Kangda New Materials and Huangma Technology, which are expanding their production capacities [9]. - It also recommends monitoring companies like Yuntianhua and Chuanheng Co., which are positioned to benefit from the increasing demand for phosphate and sulfur resources in the context of the energy transition [20][21].

Investment Rating - The report maintains an investment rating of "Outperform the Market - A" for the industry [5]. Core Insights - The civil explosives industry is experiencing a stabilization in scale, with effective integration and optimization of supply-side dynamics. The industry is projected to have a production value of 41.695 billion yuan in 2024, a year-on-year decrease of 4.50%, while the total sales value is expected to be 41.142 billion yuan, down 5.26%. However, the total profit is anticipated to grow to 9.639 billion yuan, reflecting a year-on-year increase of 13.04% [1][3][23]. Summary by Sections 1. Industry Scale and Policy Integration - The civil explosives industry is gradually stabilizing, with policies promoting integrated operations in production and blasting services. The main raw material, ammonium nitrate, remains at a low price, supporting the industry's profitability [14][19]. - The industry has seen a compound annual growth rate (CAGR) of 8.17% in production value from 2016 to 2023, with a significant increase in blasting service revenue from 8.061 billion yuan in 2016 to 35.311 billion yuan in 2024, representing a CAGR of 20.28% [1][29]. 2. Supply-Side Optimization and Industry Concentration - The civil explosives industry is undergoing significant consolidation, with the number of production enterprises decreasing from over 400 in 2005 to fewer than 50 by 2025. The top 10 enterprises' production value share has increased from 41% in 2018 to 62.47% in 2024 [2][42]. - The industry is characterized by a shift in production capacity towards the central and western regions of China, driven by demand from mining and infrastructure projects [2][3]. 3. Mining Investment Growth and Regional Demand - Investment in the mining sector is on the rise, particularly in Xinjiang and Tibet, where the demand for civil explosives is expected to increase due to ongoing coal and metal mining projects. The fixed asset investment growth in these regions is among the highest in the country [3][8]. - The civil explosives industry is projected to benefit from the ongoing construction of major infrastructure projects, such as the Yajiang Hydropower Station and the New Tibet Railway, which are expected to drive demand for explosives [3][8]. 4. Key Investment Targets - The report highlights key companies in the civil explosives sector, including Guangdong Hongda, Yipuli, Xuefeng Technology, and Gaozheng Explosives, which are well-positioned to benefit from regional demand growth and industry consolidation [8][4].

2025 年 11 月 20 日 证券Ⅱ 中金拟换股吸收合并，行业并购重组再提速 事件： 11 月 19 日晚，中金公司、东兴证券、信达证券发布《关于筹划重大资产重 组的停牌公告》，三家公司正在筹划由中金公司通过向东兴证券全体 A 股换 股股东发行 A 股股票、向信达证券全体 A 股换股股东发行 A 股股票的方式 换股吸收合并东兴证券、信达证券。 接续财政部股权划转，内生整合一脉相承。 本次合并事件涉及的三家券商均为汇金系券商。一方面，中金为汇金系券 商的重要代表。截至 2025Q3 末，中央汇金直接持有中金公司 40.11%股权。 另一方面，东兴、信达实控权现已归属中央汇金。2025 年 2 月，中国信达、 中国东方资产、中国长城资产发布公告，表示财政部拟将其持有的三家 AMC 股权全部无偿划转至中央汇金。此后推进迅速，中国长城资产、中国东方 资产、中国信达分别于 2025 年 4 月、6 月、9 月完成股权划转，东兴证券 （中国东方控股）、信达证券（中国信达控股）实控人也就此变更为中央汇 金。我们认为，本次合并事件可被视为汇金系内部券商资源的优化整合， 即在前期股权划转奠定的基础之上，优化同一控制链条下的 ...

Economic Data Overview - October economic data shows a comprehensive slowdown, with industrial added value year-on-year at 4.9%, down 1.6 percentage points from September[4] - Fixed asset investment in October decreased by 12.2% year-on-year, marking a significant drop of 5.1 percentage points, the lowest in nearly five years[7] - Real estate investment in October fell by 23% year-on-year, a decline of 1.7 percentage points from September, with new construction area down 29.5%[10] Demand and Consumption Trends - Social retail sales in October grew by only 2.9% year-on-year, a slight decrease of 0.1 percentage points, reaching a new low for the year[12] - Private investment saw a year-on-year decline of 16.8%, down 7.9 percentage points from the previous month, indicating a widening gap between private and manufacturing investments[8] Market and Policy Implications - The current economic slowdown is attributed to insufficient total demand, with a reliance on policy interventions for recovery[14] - The end of the U.S. government shutdown has not alleviated concerns, as October CPI and employment data face permanent loss risks, impacting market expectations for a December rate cut[21] - Market expectations for a December rate cut by the Federal Reserve have dropped to 44.4%, below 50%, following a shift towards a more hawkish stance among Fed officials[22]

Group 1 - The mechanical industry showed a strong performance in 2025, with a cumulative increase of 35.07%, outperforming the Shanghai and Shenzhen 300 index (17.94%) and the Shanghai Composite Index (17.99%) [1][17][21] - Emerging sectors such as AI equipment (140%), lithium battery equipment (96%), humanoid robots (67%), and engineering machinery (55%) led the gains in the mechanical industry, indicating significant investment opportunities [1][27][25] - The outlook for 2026 suggests continued growth in AI and technology sectors, with engineering machinery expected to maintain an upward trend and domestic demand gradually recovering from the bottom [1][30][39] Group 2 - Domestic economic conditions are currently experiencing a "weak recovery" phase, with fixed asset investment showing a differentiated pattern: manufacturing > infrastructure > real estate [2][30] - The general manufacturing sector is expected to enter a new investment cycle, driven by improved PPI and inventory levels, with a focus on high-end upgrades and stock replacement [39][46] - The export sector is benefiting from the competitive strength of leading Chinese companies, with a notable increase in orders for high-end machinery from Japan, reflecting the active investment in domestic high-end manufacturing [55][56] Group 3 - The AI-driven technology sector is expected to continue its upward trend, with hardware demand and new process iterations accelerating, particularly in AI PCB technology and humanoid robots [3][30][61] - Solid-state battery technology is at a critical juncture, with leading battery companies expanding production capacity, indicating a significant opportunity for battery equipment manufacturers [3][30][61] - Investment recommendations include focusing on technology growth assets such as AI PCB equipment, humanoid robots, and solid-state battery equipment, as well as engineering machinery and general automation sectors [4][61]

Investment Rating - The industry investment rating is "Leading the Market - A" and the rating is maintained [6]. Core Viewpoints - The defense and military industry indices have declined, indicating a market correction. The China Securities Military Industry Index fell by 2.02%, the China Defense Index by 1.86%, and the Shenwan Defense and Military Industry Index by 2.15% during the week from November 7 to November 14, 2025. In comparison, the Shanghai Composite Index decreased by 0.18%, the CSI 300 Index by 1.08%, and the ChiNext Index by 3.01% [1][15]. - The Shenwan Defense and Military Industry Index ranked 27th out of 31 in terms of performance among primary industries during the same period [1][18]. Summary by Sections 1. Defense and Military Market Review - The China Securities Military Industry Index closed at 11,962.63 points, down 2.02% [1][15]. - The Shenwan Defense and Military Industry Index closed at 1,671.60 points, down 2.15% [1][15]. - The index underperformed compared to the Shanghai Composite Index and the CSI 300 Index but outperformed the ChiNext Index [1][15]. 2. Individual Stock Performance - Top performing stocks included Tian'ao Electronics (+12.63%), Shanghai Huguang (+12.35%), and Aerospace Development (+8.54%) [2][19]. - The worst performing stocks included *ST Wanfang (-19.65%), Triangle Defense (-12.22%), and Aerospace Technology (-11.83%) [2][19]. 3. Key Company Announcements - Newray Energy announced a plan to reduce its shareholding by up to 3,500,000 shares [3][21]. - Aerospace and Aerospace will hold a quarterly performance briefing on November 18, 2025 [3][21]. - China Shipbuilding announced a quarterly performance briefing scheduled for November 17, 2025 [3][21]. 4. Industry News - The U.S. Department of Defense announced plans to simplify the weapon procurement process to address global threats [11][23]. - Saab and Embraer completed aerial refueling certification flights for the Gripen E fighter and KC-390 tanker in Brazil [11][23]. - The Ministry of Industry and Information Technology released a draft for the "Medium and Long-term Technology Development Plan for the Defense Industry (2026-2035)" [11][23]. 5. Investment Recommendations - Focus on the upcoming markets for gas turbines and international subcontracting businesses, highlighting companies like Triangle Defense and Wanze Shares [11][23]. - Emphasize new-generation high-end equipment sectors, including companies like AVIC Shenyang Aircraft and AVIC Chengdu Aircraft [11][23]. - Highlight opportunities in ammunition and unmanned equipment sectors [11][23].

Industry Overview - The report rates the industry as "Leading the Market - A" indicating a positive outlook for investment opportunities in the sector [1]. Key Investment Themes - The report emphasizes the ongoing global competition in technology, particularly in the computer industry, with a focus on AI and robotics as key growth areas [2][3]. - The domestic production process in critical areas such as chips, operating systems, and databases is expected to accelerate, creating opportunities for companies with lower levels of localization [3]. AI and Robotics - The AI and robotics sectors are highlighted as having vast development potential, with rapid iterations of various models and applications in both China and the US [3]. - The report identifies the need for standard upgrades in the robotics industry, presenting both challenges and investment opportunities [3]. Quantum Technology - Quantum computing is anticipated to bring disruptive innovations in computing power, with applications in quantum secure communication and anti-quantum encryption gaining traction [3][58]. - The report outlines the potential of quantum technology across four main areas: computing, communication, measurement, and anti-quantum encryption, each showing significant growth prospects [58][59]. Database Market - The database market is projected to grow significantly, with the global market size expected to exceed $100 billion in 2023, and China's market reaching approximately 74.1 billion yuan [11]. - The report forecasts a compound annual growth rate (CAGR) of 12.23% for China's database market, reaching 93.03 billion yuan by 2028 [11]. R&D Software and Measurement Instruments - The R&D design software and electronic measurement instruments sectors are characterized by high barriers to entry, strong business models, and low localization rates, indicating a favorable environment for domestic manufacturers [5]. - The report suggests that the push for technological self-sufficiency will lead to sustained growth in these sectors [5]. Cybersecurity and Encryption - The introduction of new regulations in cybersecurity is expected to drive the growth of the encryption industry, with specific guidelines enhancing the demand for secure communication solutions [21][23]. - The report highlights the importance of establishing a robust regulatory framework to support the development of the cybersecurity sector [21]. AI Glasses and Edge AI - AI glasses are identified as a promising entry point for edge AI applications, with global sales expected to reach 90 million units by 2030, reflecting a CAGR of approximately 97.42% from 2024 to 2030 [36]. - The report notes the increasing integration of AI capabilities into consumer products, enhancing user interaction and experience [36]. Recommended Companies - The report lists several companies to watch in various sectors, including R&D software (e.g., Huada Jiutian, Gacron Electronics), cybersecurity (e.g., Sanwei Xinan, Xinan Century), and quantum technology (e.g., IonQ, Rigetti) [78][80].