Group 1 - Trump threatens to significantly increase tariffs in response to stricter rare earth mineral export controls by other countries, raising concerns among investors about worsening trade relations [2][3] - The U.S. stock market experienced a sharp decline, with the Dow Jones falling by 1.9%, the Nasdaq by 3.56%, and the S&P 500 by 2.71%, marking the largest single-day drop since April [3][5] - Major tech stocks suffered significant losses, with Broadcom down nearly 6%, Tesla over 5%, and Amazon close to 5% [3][5] Group 2 - Chinese concept stocks plummeted, with the Nasdaq Golden Dragon China Index down 6.1% and a weekly decline of 8.37%, including NIO down over 10% and Bilibili down over 9% [4] - The North Rare Earth Company expects a net profit increase of 272.54% to 287.34% year-on-year for the first three quarters of 2025, projecting a profit of 1.51 billion to 1.57 billion yuan [20] Group 3 - Qualcomm is under investigation for allegedly violating antitrust laws related to its acquisition of Autotalks, as it failed to report the business concentration as required by Chinese antitrust law [2] - The price of rare earth concentrates has been raised significantly, with a 37% increase for the fourth quarter compared to the previous quarter, marking the largest increase since the second quarter of 2023 [35] Group 4 - The number of new A-share accounts in September increased by 60.73% year-on-year, with a total of 2.9372 million new accounts opened, the second-highest monthly figure this year [22] - The Chinese government is considering imposing special port fees on U.S. vessels starting October 14, 2025, as part of ongoing trade tensions [24] Group 5 - ByteDance announced a new employee subsidy policy for those laid off due to organizational adjustments, providing up to 12,000 yuan per month for a maximum of six months [17][18] - WuXi AppTec sold 30.3 million shares of its subsidiary WuXi AppTec Holdings, raising over 2.3 billion HKD [16]

【深圳商报讯】（记者 陈燕青）港股药明合联再次遭到股东药明康德的减持。药明康德10月9日晚称已 减持药明合联3030万股，套现逾23亿港元。截至10日收盘，药明康德和药明合联均下跌逾7%。 药明康德公告，公司于10月8日通过大宗交易方式，出售了其间接控股子公司所持有的药明合联3030万 股，约占其总股本的2.47%。此次交易成交金额达到约23.46亿港元（不含交易费用）。 本次减持对药明康德的财报将产生立竿见影的效果。公司称，出售的药明合联股票在账面上列为"长期 股权投资"。经公司财务部门初步测算，本次出售药明合联的投资净收益对公司2025年度税后净利润的 影响约为16.79亿元，占公司2024年归属净利润的比例超过10%。 记者注意到，最近一年药明康德已多次减持药明合联。2024年11月、2025年1月药明康德分别减持药明 合联3600万股和5000万股，累计成交金额约24.26亿港元；2025年4月，公司继续减持药明合联5080万 股，成交金额约21.78亿港元。如果加上本次减持，最近一年药明康德累计减持药明合联69.5亿港元。 ...

Core Viewpoint - WuXi AppTec's major shareholder, WuXi PharmaTech, has reduced its stake in WuXi AppTec again, selling 30.3 million shares for over HKD 2.3 billion, leading to significant stock price declines for both companies [2][4]. Group 1: Shareholder Actions - WuXi PharmaTech has conducted its fourth large-scale reduction of WuXi AppTec shares in the past year, totaling approximately HKD 69.5 billion in cash from these sales [4]. - The recent sale represents 2.47% of WuXi AppTec's total shares, with the stock price dropping by 7.29% following the announcement [2][4]. Group 2: Financial Impact - The sale of WuXi AppTec shares is classified as a "long-term equity investment," and the estimated net profit impact for WuXi PharmaTech in 2025 is approximately HKD 1.679 billion, accounting for over 10% of the company's net profit for 2024 [4]. - WuXi PharmaTech's revenue and net profit declined in 2024, with revenues of approximately CNY 39.241 billion, down 2.73%, and net profit of CNY 9.45 billion, down 1.63% [4]. Group 3: Business Performance - In 2025, WuXi PharmaTech's performance improved, with a revenue of CNY 20.8 billion in the first half, a 20.6% increase year-on-year, and a net profit of CNY 8.56 billion, more than doubling compared to the previous year [5]. - The company has a strong order backlog of CNY 56.69 billion, reflecting a 37.2% year-on-year growth, indicating sustainable performance recovery [5]. Group 4: Market Concerns - Concerns exist regarding the high proportion of overseas revenue, which accounted for over 80% of total revenue in the first half of the year, with significant contributions from U.S. clients [5]. - Geopolitical uncertainties and intensified competition in the CXO sector pose risks to long-term orders and profitability for WuXi PharmaTech [5][6]. Group 5: Strategic Moves - The continuous reduction in shareholding is seen as a strategic move to fund future global expansion, with planned expenditures of approximately CNY 7-8 billion for capacity expansion in various countries [8]. - The cash generated from the sale of WuXi AppTec shares will be used to enhance the company's integrated CRDMO business model to meet the growing demands of global clients [8].

Market Overview - A-shares and Hong Kong stocks experienced synchronized fluctuations, with the Shanghai Composite Index falling below 3900 points and the ChiNext Index dropping by 4.55% [1] - The AH pharmaceutical sector declined across the board, with major players like WuXi AppTec leading the drop at 7.2% [1] - The largest medical ETF (512170) saw a decrease of 2.03%, halting its three-day upward trend, with a total trading volume of 640 million yuan [1] Pharmaceutical Sector Performance - The A-share pharmaceutical sector showed relative resilience, primarily due to traditional Chinese medicine stocks performing well, with companies like China Resources Sanjiu and Jilin Aodong rising over 2.5% [3] - Innovative drug stocks faced more declines than gains, with BeiGene (BGNE) leading the drop at 6.2% [3] - The only drug ETF in the market (562050) fell by 1.07%, indicating increased buying interest as evidenced by 2.23 million yuan of funds entering on dips [3] Innovation Drug Sector Insights - The innovative drug sector, previously a strong performer, has entered a phase of adjustment since September, but investor interest remains high [5] - The Hong Kong Innovation Drug ETF (520880) has attracted over 675 million yuan in the last 20 days, indicating strong buying momentum despite recent declines [5] - Analysts suggest that the short-term adjustment is due to profit-taking after significant gains and a lack of catalysts, but the long-term outlook remains positive [7] Future Catalysts and Strategies - Upcoming academic conferences, such as ESMO and ASH, are expected to reignite interest in the innovative drug sector [8] - The fourth quarter will see the implementation of various policies, including adjustments to medical insurance directories, which may accelerate support for domestic innovations [8] - Investment strategies focus on identifying companies with strong Q3 performance and exploring opportunities in the innovative drug sector for potential rebounds [8] ETF Performance and Characteristics - The Hong Kong Innovation Drug ETF (520880) is fully invested in innovative drug development companies, while the drug ETF (562050) balances innovative and traditional Chinese medicine stocks [9] - The medical ETF (512170) includes medical devices and services, with a significant portion allocated to CXO [9] - As of September 30, 2025, the medical ETF has a scale of 26.4 billion yuan, making it the largest in the pharmaceutical category [10]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因依賴該等內容而引致之任何損失承擔任何責任。 WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） 海外監管公告 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B條作出。 茲載列本公司在上海證券交易所網站刊登的以下資料中文全文，僅供參閱。 承董事會命 無錫藥明康德新藥開發股份有限公司 董事長 李革博士 香港，2025年10月10日 截至本公告日期，本公司董事會包括執行董事李革博士、陳民章博士、楊青博士及張朝暉先生； 非執行董事童小幪先生及吳亦兵博士；以及獨立非執行董事盧韶華女士、俞衛博士、張新博士、 詹智玲女士及冷雪松先生。 * 僅供識別 无锡药明康德新药开发股份有限公司 简式权益变动报告书 上市公司名称：无锡药明康德新药开发股份有限公司 股票上市地点：上海证券交易所、香港联合交易所有限公司 股票简称：药明康德 股票代码：6 ...

WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因依賴該等內容而引致之任何損失承擔任何責任。 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） 海外監管公告 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B條作出。 茲載列本公司在上海證券交易所網站刊登的以下資料中文全文，僅供參閱。 承董事會命 無錫藥明康德新藥開發股份有限公司 董事長 李革博士 香港，2025年10月10日 截至本公告日期，本公司董事會包括執行董事李革博士、陳民章博士、楊青博士及張朝暉先生； 非執行董事童小幪先生及吳亦兵博士；以及獨立非執行董事盧韶華女士、俞衛博士、張新博士、 詹智玲女士及冷雪松先生。 * 僅供識別 证券代码：603259 证券简称：药明康德 公告编号：临 2025-067 无锡药明康德新药开发股份有限公司 关于股东到期解除一致行动关系暨权益变动的提示性公告 本公司董事会及全体董事及相 ...

无锡药明康德新药开发股份有限公司 简式权益变动报告书 上市公司名称：无锡药明康德新药开发股份有限公司 股票上市地点：上海证券交易所、香港联合交易所有限公司 股票简称：药明康德 股票代码：603259.SH、02359.HK | 信息披露义务人 | | 住所 | 通讯地址 | | --- | --- | --- | --- | | G&C IV | Hong Kong | Unit 826, 8/F, Ocean | | | Limited | | Centre, Harbour City, 5 | | | | | Canton Road, Tst, | 中国上海外高 | | | | Kowloon, Hong Kong | 桥 富 特 中 路 | | G&C V | Limited | PO Box 309, Ugland | 号 | | G&C VI | Limited | House, Grand Cayman, | 288 | | | | KY1-1104, Cayman | | | G&C VII | Limited | Islands | | | 嘉兴厚锦投资合伙 | | 浙江省嘉兴市南湖区 883 ...

南财智讯10月10日电，药明康德公告，公司原一致行动人与实际控制人之一GeLi（李革）签署《一致 行动关系解除协议》，导致信息披露义务人合计可支配表决权比例从20.16%下降至18.46%，触及5%的 整数倍刻度。此外，自2023年8月30日至2025年10月9日期间，因回购和注销A股及H股、A股期权激励 计划项下行权、增发H股、H股可转换债券转股等原因，公司总股本发生变动，信息披露义务人持股比 例被动变化。变动后，公司实际控制人GeLi（李革）、张朝晖、刘晓钟合计控制公司18.46%的表决 权。信息披露义务人尚无在未来12个月内增加或减少药明康德股份的明确计划。 ...

关于股东到期解除一致行动关系暨权益变动的提示性公告 本公司董事会及全体董事及相关股东保证本公告内容不存在任何虚假记载、 误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 证券代码：603259 证券简称：药明康德 公告编号：临 2025-067 无锡药明康德新药开发股份有限公司 重要内容提示： 本次权益变动因无锡药明康德新药开发股份有限公司（以下简称"公司" 或"药明康德"）股东到期解除一致行动关系、已完成的公司总股本因回购注销 A 股及 H 股股份、A 股期权激励计划项下行权、增发 H 股及 H 股可转换债券转 股变动以及部分信息披露义务人股份交易所触发。 本次权益变动不涉及公司实际控制人变化，亦不会对公司的治理结构、 日常经营活动产生影响。 原一致行动人（定义见下文）已出具书面承诺在未来 6 个月内不以任何 方式减持、变相减持、赠与或处置所持有的药明康德的股票或采取任何以实现股 份处置收益效果为目的的行动，亦不会以任何方式对所持有的药明康德的股票设 置质押担保或其他任何方式的担保措施或其他权利负担，且截至本公告日，公司 实际控制人控制或签署投票委托书的股东均无减持公司 A 股股票的 ...

Group 1 - Jieqiang Equipment has completed the acquisition of 51% stake in Shandong Carbon Seeking, which will now be included in the company's consolidated financial statements [1] - Tonghua Dongbao's insulin injection product has received marketing approval in Myanmar for diabetes treatment [1] - New Light Optoelectronics' actual controller plans to increase shareholding by 5 to 10 million yuan within six months [2] Group 2 - Far East Holdings received contracts worth 1.769 billion yuan in September [3] - Poly Developments reported a 1.84% decrease in signed sales amount in September, totaling 20.531 billion yuan [4] - ST Nuotai expects a net profit increase of 5.62% to 13.74% for Q3 2025 [7] Group 3 - Chongqing Port's controlling shareholder plans to merge with another entity, changing the controlling shareholder to Chongqing Logistics Group [9] - New Energy Company reported a 28.21% increase in cumulative power generation from January to September [11] - Dashiang Co. announced the resignation of its chairman due to personal reasons [12] Group 4 - Liao Port Co. announced the resignation of a non-executive director due to work changes [13] - Zhongzai Resources received a government subsidy of 5.33 million yuan, accounting for 23.72% of its audited net profit for 2024 [14] - Xiaoming Co. reported a sales revenue of 66.15 million yuan from chicken products in September [15] Group 5 - Tianyi Co. signed a framework contract worth 23.50 million yuan for e-business network terminal production [16] - Jingu Co. signed a strategic cooperation agreement with Ninebot Technology for lightweight materials [18] - Tianbang Foods reported a sales revenue of 634 million yuan from commodity pigs in September [20] Group 6 - Shaanxi Energy's subsidiary received an administrative penalty for safety violations, resulting in a fine of 940,000 yuan [22] - North Bay Port reported a 9% increase in cargo throughput in September [23] - Tangrenshen reported a sales revenue of 639 million yuan from pig sales in September [24] Group 7 - Dabeinong reported a sales revenue of 541 million yuan from pig sales in September [25] - Jiukang Bio obtained four medical device registration certificates [26] - Canan Co. invested 90 million yuan in structured deposits with a bank [27] Group 8 - Zhuhai Port reported a 5.44% decrease in cargo throughput in Q3 [28] - Jinli Yongmag expects a net profit increase of 157% to 179% for the first three quarters [29] - Huamao Logistics' controlling shareholder plans to increase shareholding by 64.5 to 129 million yuan [30] Group 9 - Dongjie Intelligent signed a 50 million yuan contract for intelligent warehousing in the steel industry [31] - Sais Technology signed a cooperation framework agreement with Volcano Engine for intelligent robotics [32] - Huadong Pharmaceutical's subsidiary received approval for clinical trials of a new drug targeting advanced solid tumors [34] Group 10 - TCL Technology completed the acquisition of 80% and 100% stakes in LG Display's subsidiaries for 11.088 billion yuan [34] - Shuangliang Energy won a 419 million yuan EPC project for cooling systems [36] - Ruina Intelligent announced plans for shareholders to reduce their stakes by up to 1.18% [38] Group 11 - Baodi Mining announced plans for shareholders to reduce their stakes by up to 5.45% [40] - Xinyi Technology's shareholders set the transfer price for shares at 328 yuan each [42] - Sunshine Power submitted an application for H-share listing on the Hong Kong Stock Exchange [44] Group 12 - Qisheng Technology's controlling shareholder plans to reduce their stake by up to 3.09% [46] - Wu Ming Kangde sold 30.3 million shares of Wu Ming He Lian through block trading [48] - Qiaoyin Co. announced plans for shareholders to reduce their stakes by up to 6% [49] Group 13 - Muyuan Foods reported a sales revenue of 9.066 billion yuan from commodity pigs in September [51] - Huawang Technology's shareholders plan to reduce their stakes by up to 1.1% [53] - Huaxin Xinchuang received a project notification from Lantu Automotive for display components [54] Group 14 - China Merchants Shekou reported a signed sales amount of 16.698 billion yuan in September [55] - Shao Neng Co. received approval for an antitrust review regarding a share acquisition [57] - Pengding Holdings reported a 6.21% increase in consolidated revenue in September [58] Group 15 - Ganfeng Lithium is advancing its solid-state battery commercialization and strategic investment in the energy storage sector [59]