白血病是因血液细胞发生异常并转化为癌细胞进而增殖的疾病。日本国立癌症研究中心的"癌 症统计"（全国癌症登记）数据显示，日本国内每年确诊的白血病患者约有1.5万人。 治疗白血病的方法之一是清除异常血液细胞，并移植与患者白血球类型高度相似的供体的"造 血干细胞"。但这种方法存在的问题是往往需要耗费大量时间寻找亲属等供体。 河本教授等人的团队已经在京都大学医院的设施中开始进行细胞生产（图片由京都大学的永野诚治助教提供） 研究团队将利用经过处理以降低排异反应的第三方iPS细胞，培育出攻击癌细胞的杀伤性T细 胞。用于治疗急性骨髓性白血病，可省去白血病的传统移植造血干细胞治疗中寻找供体的时 间…… 日本京都大学计划最早2027年启动利用iPS细胞的白血病新疗法的临床试验。新疗法将采用 以符合条件的健康人细胞为基础制备的iPS细胞。可省去白血病的传统移植治疗中寻找供体的 时间。研究团队将验证安全性及有效性等，力求早日投入实际应用。 本次由医师主导的临床试验将在京都大学医院开展。制备好的杀伤性T细胞将被用于65岁以上 的急性骨髓性白血病患者，以验证安全性和有效性。 如果能将预先制备的杀伤性T细胞冷冻保存，便无需再为寻找供体耗 ...

Core Viewpoint - Sushiro's overseas business, particularly in China, is performing exceptionally well, with expectations that overseas revenue will exceed 35% by the fiscal year 2026 [2][4]. Group 1: Company Performance and Strategy - F&LC's market capitalization surpassed 1 trillion yen in August, driven by growth expectations in overseas markets, especially in China and Southeast Asia [2]. - The company aims to increase operating profit to 1 trillion yen by the fiscal year 2035, which is 2.3 times the previous fiscal year's profit [2]. - As of October 2024, the number of overseas stores reached 232, a 30% increase from the previous year, with overseas revenue growing by 43% to 131.4 billion yen, accounting for 31% of total revenue [4][5]. Group 2: Competitive Landscape - Competitor Kura Sushi is exiting the Chinese market, while Sushiro is expanding its store network in Asia, including a recent entry into Malaysia [4][5]. - Kura Sushi has established a presence in the U.S. with 81 stores and reported sales of $282.8 million for the fiscal year ending August 2025 [8]. - Sushiro's strategy focuses on delivering authentic Japanese sushi, which may face challenges in gaining recognition in the U.S. market [9]. Group 3: Financial Outlook - F&LC's financial report for the fiscal year 2025 showed better-than-expected results, with a stock price increase of 4% following the announcement [7]. - The company anticipates a record net profit of 24 billion yen for the fiscal year 2026, although this is below market expectations [7]. - F&LC's equity ratio is 24%, which is lower compared to competitors, indicating reliance on debt for growth, raising concerns about financial pressure amid rising interest rates [11]. Group 4: Future Expansion Plans - F&LC plans to increase the number of stores in the U.S. to 100 and in China to 500 by the fiscal year 2035, aiming for a total revenue of 1 trillion yen [11].

Core Viewpoint - Japanese fresh fruit and vegetable exports, particularly grapes, are experiencing significant declines, with a potential record drop in export value for the year, attributed to increased competition from South Korean and Chinese products and a lack of effective branding strategy to counteract this competition [2][6][8]. Group 1: Export Performance - Japan's fresh fruit and vegetable export value grew only 1% year-on-year from January to October 2025, a sharp decline from a 9% growth in 2024 [2][4]. - The export value of grapes specifically fell by 20% year-on-year, with a 22% decrease in export volume by the end of October [6]. - The overall export value of agricultural and food products reached a record high of 1.4092 trillion yen in 2024, with a 15% year-on-year increase from January to October [2]. Group 2: Competitive Landscape - The market for high-end grapes, such as the Sunshine Rose variety, is facing stiff competition from lower-priced and higher-quality grapes from South Korea and China [4][6]. - The production area for grapes in South Korea and China has been expanding, allowing these countries to compete effectively in markets like Hong Kong and Taiwan, where Japanese grapes previously dominated [8]. - Japanese grapes are struggling to meet the quality and size demands of export markets, exacerbated by domestic climate challenges and inconsistent quality across production regions [8]. Group 3: Historical Context and Challenges - The decline in Japan's grape exports can be traced back to a seedling outflow incident nearly a decade ago, which allowed popular varieties like Sunshine Rose to be cultivated in other countries [6][9]. - The Japanese government has implemented measures to restrict seedling outflow, but protecting intellectual property for already outflowed varieties remains challenging [8][9]. - Experts suggest that Japan needs to improve its agricultural productivity and establish a strong reputation for quality to compete effectively against lower-priced imports [9].

斯巴鲁的SUV"森林人"（12月4日，横滨市） 大众的纯电动MPV"ID.Buzz"（12月4日，横滨市） 此外，"2025-2026年度进口汽车"选择了德国大众的纯电动车型"ID.Buzz"。其设计让人联 想到被亲切地称为"Wagen Bus"的小型MPV"Type 2"，该车同时属于日本国内仍然稀少的 纯电动MPV，获得高度评价。 版权声明：日本经济新闻社版权所有，未经授权不得转载或部分复制，违者必究。 日经中文网 https://cn.nikkei.com 视频号推荐内容： 斯巴鲁4月发售了第6代新款森林人。由自主开发的发动机和丰田提供的混合动力系统组合成 的动力单元"强混动"（Strong Hybrid）获得很高评价。既能日常使用也能越野的性能和外型 设计引人关注…… 由汽车评论家等组成的日本年度汽车执行委员会12月4日宣布，作为最优秀奖的"2025-2026 年度日本年度汽车"颁给SUBARU（斯巴鲁）的SUV车型"森林人"（Forester）。评委对森林 人的燃效性能和乘坐舒适度等给予高度评价。 斯巴鲁4月发售了第6代新款森林人。由自主开发的发动机和丰田提供的混合动力系统组合成 的动力单元"强混动 ...

Core Viewpoint - "Anywit Robotics" has completed a multi-million Pre-A round financing, with funds aimed at enhancing standardized products and upgrading emotional interaction models [6][8]. Group 1: Company Overview - "Anywit Robotics" was established in December 2023, focusing on creating multi-modal interactive robots with "vitality" [8]. - The company has launched humanoid robots with high degrees of freedom, totaling 34 degrees, enabling human-like expressions and interactions [8]. - The facial interaction components are equipped with multi-modal large models and self-developed emotional generation models, facilitating emotional interaction experiences with users [8]. Group 2: Product Development and Market Application - "Anywit Robotics" is advancing commercialization, having introduced interactive robots with expressive facial components for applications in education, marketing, and entertainment [8][10]. - The company has already delivered educational robots, achieving standardized products that allow robot teachers to enter elementary school classrooms [10]. - The CEO believes that innovation in interaction modes will drive product penetration, similar to how graphical interfaces and touchscreens revolutionized computing and mobile internet [10]. Group 3: Future Outlook and Team Expertise - The company anticipates large-scale shipments of standardized facial components by 2026 [10]. - The core team consists of graduates from the University of Science and Technology of China, with nearly 10 years of experience in human-robot emotional interaction research [10]. - The investment firm, Yunxiu Capital, highlights the rapid development of embodied intelligence and the potential for mature facial expression interaction technology to create numerous productization scenarios [10].

从东南亚等地区经日本中转运往美国的货物正在增加 2024年度，Temu、SHEIN的电商运输量激增，中国大陆赴美航空货物运费上涨波及日本。 2025年度以后，东南亚、台湾等的赴美航空货运量增长，半导体等的运输经由日本，对日本 的运费形成支撑…… 日本发往美国的航空货物运费持续保持在高位。2025年度下半年的运费谈判最终以持平区间 达成协议，维持了2024年大幅上涨后的水平。虽然日本出发的货物增长乏力，但东南亚等经 由日本发往美国的货物运输需求坚挺，支撑了运费行情。 航空货物通过货机或客机腹舱进行运输。向航空公司采购舱位的拼箱货运代理商 （forwarder）会与货主企业进行谈判，敲定半年或一年的合约运费。一般情况下，航空公司 与货运代理商之间、货运代理商与货主之间均会在每年4月（上半年）和10月（下半年）进行 两次运费调整。 2025年度下半年，东京发往美国东海岸的运费为每公斤1020~1220日元左右，东京发往美国 西海岸的运费为每公斤960~1100日元左右。谈妥的运费与上次谈判持平，维持了2024年度 大幅上涨后的水平。 2024年度运费暴涨的原因是Temu、SHEIN等源自中国的电商平台的运输量激增。 ...

Core Viewpoint - Toyota has unveiled three flagship models, including the successor to the high-end sports car "LFA," aimed at enhancing brand appeal and adding value in the context of increasing vehicle commoditization and a shift towards electric vehicles [2][4]. Group 1: Model Details - The three models introduced are the flagship "GR GT," the race-performance "GR GT3," and the pure electric "Lexus LFA Concept," with the latter's release date yet to be determined [4]. - All three models feature an aluminum body structure and incorporate Toyota's latest technologies, representing the pinnacle of the company's engineering capabilities [2][5]. Group 2: Historical Context - The introduction of these models continues the legacy of Toyota's high-performance vehicles, tracing back to the "2000GT" launched in 1967, which achieved world-leading speed and acceleration at the time [5]. - The previous "LFA," released in 2010, was notable for its carbon fiber reinforced plastic (CFRP) body and a 4.8-liter V10 engine, showcasing Toyota's commitment to high-performance engineering [5]. Group 3: Development Philosophy - Toyota's president, Akio Toyoda, emphasized the motivation behind the development of these vehicles, stating that the company aims to transform past disappointments in racing into a driving force for creating better cars [4].

Core Viewpoint - The ongoing geopolitical tensions between China, the U.S., and Japan are significantly impacting the rare earth market, with prices continuing to rise despite temporary measures to delay stricter export controls from China [2][6]. Group 1: Rare Earth Prices - Rare earth prices are experiencing a significant increase, with cesium reaching $910 per kilogram, over three times the pre-export control level, and terbium at $3,700 per kilogram, approximately four times higher, marking the highest levels since May 2015 [4]. - The market remains skeptical about the effectiveness of the U.S.-China agreements, with analysts predicting that high prices will persist due to ongoing supply concerns, particularly for markets outside the U.S. [6][9]. Group 2: Export Controls and Geopolitical Tensions - China has been limiting the export of rare earths since April, with new regulations requiring permits for products containing even small amounts of Chinese rare earths [6]. - Following the October U.S.-China summit, China postponed the implementation of stricter export controls for one year, while the U.S. delayed imposing additional tariffs [6][7]. - Concerns are rising regarding Japan's relationship with China, reminiscent of past export halts, prompting Japanese companies to consider sourcing rare earths outside of China [9]. Group 3: Gallium Market - Similar to rare earths, gallium prices are also on the rise, with prices reaching $1,325 per pound, approximately 2.3 times higher than at the beginning of the year, marking the highest level since 2002 [7]. - China's dominance in gallium production is notable, with 99% of the output expected to be from China by 2024, and existing export controls are likely to remain in place for regions outside the U.S. [6][7].

Core Viewpoint - President Trump has expressed interest in promoting the production of small cars in the U.S., inspired by his observations during his visit to Japan and South Korea, where he noted the popularity of compact vehicles like the Volkswagen Beetle [2][3][5]. Group 1: Small Car Production - Trump has instructed U.S. Transportation Secretary Chao to approve the production of small cars, indicating a positive reception from those he consulted about their potential popularity in the U.S. market [5]. - The specific type of small cars mentioned by Trump remains unclear, as he did not specify whether he was referring to compact cars or Japan's kei cars [6]. - Honda's N-BOX, a well-known kei car, was highlighted by Trump, who noted that despite its success, it has not been approved for production in the U.S. [6]. Group 2: Market Potential - Trump emphasized the importance of affordability in the automotive market, suggesting that the removal of certain tariffs on food is an example of this focus [6]. - He stated that if small, affordable cars become more prevalent, it could represent a significant market opportunity for consumers [6].

Group 1 - Nissan has launched a completely redesigned microvan "Elgrand" for the first time in 16 years, which is expected to be a key model in its new vehicle strategy [5][6] - The new model's release has been delayed, leading to criticism from dealers who accuse the company of being "irresponsible" [6] - The delay in the new vehicle's development is attributed to management's postponed decision-making processes [6]