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医药估值重估逻辑
雪球· 2025-06-25 07:47
Core Viewpoint - The game rules for innovative drugs have changed by 2025, with overseas giants valuing early-stage R&D in China, prompting institutions to reassess their valuations and investment strategies [11] Group 1: Historical Context - Previously, investment institutions focused only on "quickly sellable drugs," disregarding early-stage pipelines due to high risks, with a failure rate of 90% in early projects [2] - Traditional valuation models, such as PE ratios, only considered current profits, leading to the neglect of early pipeline values in innovative drug companies [3] Group 2: Changes by 2025 - Starting in 2025, major pharmaceutical companies like Pfizer and Merck began aggressively acquiring Chinese innovative drug pipelines, especially early-stage projects, with notable transactions such as a $12.5 billion upfront payment for a PD-1/VEGF dual antibody from 3SBio, totaling $60.5 billion [4] - The technological advancements in Chinese innovative drugs have shifted from imitation to global leadership, exemplified by BeiGene's cancer drug generating $2.6 billion in annual sales in the U.S. [5] - The expiration of patents for major drugs has led to increased acquisitions from China [6] Group 3: Industry Reactions - Pharmaceutical companies are investing heavily in early-stage projects, with 35% of the 672 billion yuan spent on R&D in 2024 directed towards early-stage initiatives [7] - CRO companies are experiencing a surge in orders as pharmaceutical firms outsource early-stage research, with AI technologies reducing research timelines and increasing demand for CRO services [8] Group 4: Investment Logic Transformation - The investment logic has shifted from counting "fruits" (marketed drugs) to counting "buds" (potential future products), utilizing new algorithms like rNPV to assess pipeline success rates and future earnings [9] - The secondary market has responded positively, with the PE ratio for innovative drug stocks in Hong Kong rising from 15x to 22x [10]
大涨!牛市旗手大爆发,有券商单日暴涨100%!千亿资金涌入!股民:券商不演了,牛回速归....
雪球· 2025-06-25 07:47
Group 1: Market Overview - The three major indices collectively rose, with the Shanghai Composite Index up 1.03%, Shenzhen Component Index up 1.72%, and ChiNext Index up 3.11% [1] - The total market turnover reached 16,394 billion, an increase of 1,915 billion compared to the previous day, with over 3,900 stocks rising [1] Group 2: Brokerage Sector Performance - The brokerage sector has seen three consecutive days of gains, with a significant inflow of 100 billion today, resulting in an overall increase of 4.54% in the sector [2][4] - Notable stocks such as Guosen Securities and Xiangcai Securities have hit the daily limit, while others like Dongfang Caifu and Guotai Junan also experienced gains [4] Group 3: Policy Support for Financial Sector - Recent guidelines from multiple financial regulatory bodies aim to bolster macroeconomic foundations and stabilize consumer expectations, emphasizing the use of various monetary policy tools to maintain liquidity and lower financing costs [4] - The guidelines also focus on enhancing the capital market's function in coordinating investment and financing, promoting the entry of long-term funds into the market [4] Group 4: Financial Sector Outlook - CITIC Securities reports that the financial sub-industry benefits from favorable macro and industrial policies, a low-interest-rate environment, and the emergence of core competitiveness among top financial institutions [5] - The report suggests that two types of companies will benefit: high-quality index-weighted stocks and growth stocks expected to outperform industry benchmarks within three years [5] Group 5: Hong Kong Brokerage Developments - Guotai Junan International has received approval from the Hong Kong Securities and Futures Commission to upgrade its existing securities trading license to provide virtual asset trading services, allowing clients to trade cryptocurrencies and stablecoins directly [7] Group 6: Alcohol Industry Insights - The price of Feitian Moutai has dropped, with the wholesale reference price for 2025 Feitian Moutai original box down by 85 yuan to 1,830 yuan per bottle, and the scattered bottle price down by 70 yuan to 1,780 yuan [9] - Despite initial declines, the liquor sector saw a slight recovery, closing up 0.18% as market sentiment improved due to the brokerage sector's performance [9] Group 7: Military Industry Trends - The military sector experienced a significant rise, with multiple stocks hitting the daily limit, including Changcheng Military Industry, which has seen five consecutive days of gains [12] - Research indicates that the military industry is entering a new development phase with the upcoming "14th Five-Year Plan" and increased public interest due to commemorative events related to historical victories [14]
42年不调仓,年化收益6.8%,竟然是这样一个简单到离谱的策略....
雪球· 2025-06-24 10:49
以下文章来源于府库 ,作者府库 府库 . 规划投资理财,温暖幸福生活 风险提示:本文所提到的观点仅代表个人的意见,所涉及标的不作推荐,据此买卖,风险自负。 作者:府库 来源:雪球 在最开始几年做投资的时候,一直有一个词叫做"交易系统",意思是有一套明确的规则,来指导在投资时的买入与卖出,这样就可以规避掉人为因 素在其中的影响。在那时觉得投资中不应该掺杂个人主观判断,但一直都没法达成这样的目标,过程也很不舒服。 但对于咱们来说,适合追求绝对理性的投资么? 01 固定比例的永久组合 之前我去翻看了永久投资组合基金(The Permanent Portfolio Fund)的历史,在42年的时间内获得了6.8%的年化收益。它就是非常典型的以基金开 始时,就设置好了资产类别与配置比例,只做平衡而不作改变的实例。 基金的投资组合,是20%的资产投资于黄金,5%的资产投资于白银,10%的资产投资于瑞士法郎资产,15%的资产投资于房地产和自然资源股票, 15%的资产投资于激进增长股票,以及 35%的资产投资于美元资产。 回顾历史,这个投资组合在设定初期有它的合理性,但是经历了几十年的时间,像瑞士法郎的配置价值已经发生了根本 ...
这个方向,券商研报说存在56%的上涨空间
雪球· 2025-06-24 07:29
以下文章来源于阡陌说 ,作者阡陌说 阡陌说 . 雪球2022年度基金影响力用户,天天基金2024年度影响力牛人。公众号大部分为基金学习笔记,可能会略显枯燥,感谢您的关注!期待与您同行收获时间 的玫瑰。 风险提示:本文所提到的观点仅代表个人的意见,所涉及标的不作推荐,据此买卖,风险自负。 作者:阡陌说 来源:雪球 最近,我发现很多文章提及了金银比。 金银比是啥呢?它是反映黄金与白银之间的相对价格关系的一个指标,通常用于衡量白银是否被低估或高估。金银比越高,说明白银相对于黄金越 便宜,反之则越贵。 从历史数据来看,金银比在2025年4月一度升至104,随后随着白银价格的补涨,金银比逐步回落。截至2025年6月20日,COMEX黄金为3384.4美 元/盎司,COMEX白银为35.95美元/盎司,金银比最新值是94.14。 数据来源:WIND,截至2025年6月20日,历史收益不预示未来走势 数据来源:WIND,截至2025年6月20日,历史收益不预示未来走势 一、逻辑支撑 2.1、白银素有"魔鬼金属 "之称,波动率是黄金的1.5倍。 2.2、金银比的修复并非单边趋势,而是受多重因素影响的过程,短期波动可能较大,投 ...
停火!全球股市大涨!上证重回3400!牛市旗手爆发!高盛:超配中国!沪深300目标4600!
雪球· 2025-06-24 07:29
A股三大指数今日集体走强,沪指再度站上3400点关口。 截止收盘,沪指涨1.15%,深证成指涨1.68%,创业板指涨2.30%。沪深两市成交额超过1.4万亿,较昨日大幅放量近3000亿。 行业板块多数收涨,电机、电池、汽车零部件、游戏、包装材料板块涨幅居前,石油行业、燃气、航运港口、贵金属板块跌幅居前。 01 "停火现已生效,请勿违反" 在周末的美军对伊朗的关键核设施史无前例的轰炸后,不少人担心担心伊朗会干扰供应以报复美国,目前看来冲突扩大的可能性已经大幅下降。 伊朗23日发表声明说,为回应美国对伊朗核设施的侵略行径,伊朗当天对美国驻卡塔尔的乌代德空军基地进行了导弹打击。"这似乎是精心策划的,伊朗袭击了一个空无一人的美国基地,提前发出了大量警告,并关闭了领空,还提供了躲避指引。"Onyx Capital Group 研究部主管Harry Tchilinguirian说:"伊朗做出了面子上的回应,远离了霍尔木兹海峡。" 在此消息后,国际原油期货结算价大幅收跌,WTI原油期货8月合约跌7.22%,布伦特原油期货8月合约跌7.18%。当日美股三大指数均涨近1%,亚太股市在早间开盘后也集体上扬,上证突破3400这一重 ...
新消费VS旧消费,消费投资风向“变天”的背后
雪球· 2025-06-24 07:29
Core Viewpoint - The article discusses the significant divergence in performance between new and old consumption sectors in 2024, highlighting the strong growth of new consumption brands like Pop Mart and Lao Pu Gold compared to the stagnation of traditional sectors like liquor and condiments [4][5]. Group 1: Changes in Consumption Investment Logic - The investment logic in consumer stocks is shifting from "alcohol content" to "new content," driven by evolving consumer needs and preferences [5]. - As material needs are met, consumers are increasingly seeking products that fulfill psychological and social desires, leading to the rise of new consumption brands that cater to younger demographics [6]. - Economic conditions influence consumer spending power, with current trends favoring value-driven purchases as consumers prioritize cost-effectiveness amid economic uncertainty [9][10]. Group 2: New Consumption Investment Opportunities - New consumption companies have shown remarkable stock performance, with Pop Mart and Lao Pu Gold significantly contributing to the growth of various funds [12]. - As of Q1 2025, 207 funds held Pop Mart shares worth approximately 9.928 billion yuan, with notable funds achieving net value growth rates of 61.6% and 58.74% [12][13]. - The emergence of new consumption has been characterized by a mix of market replacement and cultural expansion, indicating higher growth potential compared to traditional sectors [11]. Group 3: Reasons for Missed Investment Opportunities - Different responses and strategies among fund managers have led to varied outcomes in capitalizing on new consumption trends, influenced by their understanding and investment frameworks [15]. - Older fund managers may struggle to grasp the appeal of new consumption products, while younger managers are more attuned to these trends, impacting their investment decisions [16]. - Regulatory constraints and the structured investment process in public funds can limit the ability to invest in emerging new consumption stocks, which may not fit established investment criteria [17]. Group 4: New Consumption vs. Old Consumption - The valuation of new consumption stocks has surged, with high price-to-earnings ratios indicating potential risks if growth expectations are not met [20]. - In contrast, traditional consumption stocks like Kweichow Moutai and Haitian Flavoring have seen valuation compression, presenting a more stable investment opportunity [21]. - The article suggests that while new consumption is currently favored, traditional sectors are adapting and may present future opportunities as they innovate and enhance shareholder returns [24]. Group 5: Conclusion - Investors are advised to choose between new and old consumption based on their risk tolerance, with a focus on long-term value and growth potential [25].
美的与格力定性对比
雪球· 2025-06-23 07:47
Group 1: Corporate Governance - Midea is a company capable of continuous improvement and transformation, with strong management iteration ability. The transition of the chairman position from He Xiangjian to Fang Hongbo reflects the need for professional managers rather than relying on family members [3] - Midea's historical transformations have led to significant growth, with a notable shift to a divisional management structure in 1997 that resulted in explosive sales growth post-1998 [3][4] - After experiencing a slowdown in growth post-2010, Midea implemented a flattening reform in 2012 to address organizational inefficiencies, which ultimately led to improved agility and performance [5][6] Group 2: Channel Transformation - Midea's early completion of the T+3 transformation in its distribution channels allowed for profit recovery and provided the confidence to initiate a price war in 2019, surpassing Gree in market share [14] - Gree, while historically strong in channel management, has been slower to adapt to the digital era, leading to inefficiencies in its traditional distribution model [18] Group 3: Diversification - Midea's diversification strategy is cautious and primarily related, focusing on expanding within the home appliance sector while ensuring new product lines are developed under its divisional structure [20] - Gree's diversification includes some blind spots, such as its investment in the electric vehicle sector, which lacks synergy with its core business in home appliances [20] Group 4: Capital Allocation - Since its IPO in 2013, Midea has achieved a cumulative net profit of 275 billion, with a historical dividend payout ratio of 48.9% [22] - Gree has a slightly higher historical dividend payout ratio of 49%, but Midea has provided a more consistent and increasing dividend payment experience for shareholders [23][25] - Gree has engaged in significant share buybacks, totaling 30 billion, which has reduced its total share capital by 6.89% [27][30] Group 5: Valuation and Investment Perspective - Gree's lower valuation (TTM PE of 7.5) compared to Midea (TTM PE of 13) suggests a higher cash flow return for Gree, making it an attractive investment despite concerns over governance and organizational iteration [31][32] - The potential for Gree's valuation to increase is higher due to its low static valuation and recent improvements in channel management, which could lead to better market recognition [32][33] Group 6: Market Position and Competition - Gree has established a strong brand presence in the air conditioning market, but its high pricing strategy has led to a decline in market share as competitors like Xiaomi and Aux gain traction [41] - The competitive landscape indicates that while Gree maintains a top position, it risks depleting its brand equity if it does not adapt to market changes [41]
银行股:选能涨的,还是选优秀的?
雪球· 2025-06-23 07:47
Core Viewpoints - The investment strategy for bank stocks should focus on two main approaches: selecting high-quality banks that can withstand market fluctuations and choosing banks with significant growth potential, particularly those with low valuations that have outperformed in recent years [2][3]. Group 1: Investment Strategies - The first strategy emphasizes investing in high-quality banks such as Jiangsu Bank and Hangzhou Bank, which offer strong performance and dividend yields, making them resilient during market downturns [2][3]. - The second strategy highlights the importance of selecting banks that have shown substantial price increases, even if they are not considered high-quality, as seen with large banks and rural commercial banks outperforming city commercial banks in recent years [2][3]. Group 2: Market Cycles and Bank Selection - The banking sector has experienced a downward cycle since 2015, with a focus on risk management and bad debt resolution, leading to a preference for banks with strong fundamentals during this period [3][4]. - As the banking sector enters an upward cycle, banks with cleared bad debts and stable net interest margins become more attractive, especially those with previously low valuations [3][4]. Group 3: Current Market Outlook - In a declining market, even high-quality banks may face initial declines, but those with strong fundamentals and cleared bad debts will eventually see their value recognized [4][5]. - The current outlook favors banks that have undergone bad debt cycles and are now positioned for growth, such as Qingdao Bank and Huishang Bank, which are expected to see significant price increases [5][6].
A股市值一哥,强势六连阳!万亿巨头携手新高!险资再现举牌潮,这一板块有何魔力?
雪球· 2025-06-23 07:47
Market Overview - A-shares opened lower but rose throughout the day, with the Shanghai Composite Index up 0.65%, the Shenzhen Component Index up 0.43%, and the ChiNext Index up 0.39%, with over 4,400 stocks rising [1] Banking Sector - Bank stocks reached new highs, with major banks like ICBC, ABC, and CCB seeing significant price increases. ICBC's stock rose by 2.04%, marking six consecutive days of gains, with a total market capitalization of 2.68 trillion yuan [4][6] - Insurance capital has been actively increasing stakes in bank stocks, with 15 instances of stake increases this year. Major insurers involved include Ping An Life and China Life, driven by expectations of future returns and high dividend yields [6][7] Cross-Border Payment - The cross-border payment concept surged, with stocks like Sifang Jingchuang hitting a 20% limit up. The launch of the cross-border payment system on June 22 is expected to facilitate real-time remittances between mainland China and Hong Kong [9][11] - Morgan Stanley views the cross-border payment system as a mild benefit for financial stocks, predicting it will attract more liquidity to Hong Kong [11][12] Oil and Gas Sector - The Iranian parliament's approval to potentially close the Strait of Hormuz has led to a strong performance in the oil and gas sector, with stocks like Junyou and Beiken Energy seeing significant gains [15][17] - The Strait of Hormuz is a critical passage for global oil trade, and any disruption could lead to oil prices exceeding $120 per barrel [18] Semiconductor Sector - The semiconductor equipment sector saw strong gains, with companies like Zhongwei and Tuojing Technology rising over 4%. The potential withdrawal of exemptions for U.S. technology use by major semiconductor manufacturers has raised concerns but also highlighted opportunities for domestic companies [20][22] - Analysts predict a recovery in the semiconductor industry driven by AI demand and ongoing domestic substitution efforts, with positive revenue and profit growth expected in 2024 and early 2025 [23]
“别把所有鸡蛋放一个篮子"的投资智慧,现在还行得通吗?
雪球· 2025-06-22 12:36
Core Viewpoint - The article discusses the impact of geopolitical risks and market volatility on investment strategies, emphasizing the importance of diversification in investment portfolios to mitigate risks in a changing environment [2][3]. Group 1: Diversification Concept - Diversification is described as the only "free lunch" in investing, where the overall risk of a portfolio is not merely the sum of individual asset risks but is influenced by the interactions between assets [3][5]. - The correlation coefficient is a key metric for understanding the relationship between asset price movements, with values ranging from 1 (perfectly correlated) to -1 (perfectly inversely correlated) [4][5]. - Combining assets with correlation coefficients below 1 can reduce overall risk, and lower correlation enhances the effectiveness of diversification [5][8]. Group 2: Historical Context and Changing Correlations - Historical data shows that correlations between A-shares and global markets fluctuate, indicating that past effective diversification strategies may not hold in the future [9][10]. - Since 2021, the correlation between A-shares and developed markets like the US and Japan has decreased, enhancing the diversification value for A-share investors [13]. - Conversely, correlations with emerging markets have increased since 2017, partly due to China's growing weight in emerging market indices [13][14]. Group 3: Building a "Anti-Fragile" Portfolio - The article suggests that merely investing in overseas assets is insufficient for effective risk diversification; a more comprehensive approach is needed that spans multiple asset classes [19][20]. - The changing correlation dynamics among major asset classes highlight the complexity and challenges of constructing a diversified investment portfolio [21][22]. - Continuous monitoring of asset correlations and dynamic adjustments to the portfolio are essential for effective management in a complex investment environment [23].