Investment Rating - The investment rating for the company is "Buy" (maintained) [2][9] Core Views - The company has signed a licensing agreement with Pfizer for the PD1×VEGF dual antibody SSGJ707, receiving an upfront payment of $1.25 billion, which is the largest for a Chinese innovative drug license-out, along with potential milestone payments of $4.8 billion and double-digit royalties on net sales [4][6] - The company is expected to achieve revenue growth of 12% to 14% from 2025 to 2027, with projected revenues of 102.01 billion, 114.94 billion, and 131.53 billion yuan respectively [6] - The company is anticipated to see a significant acceleration in domestic revenue due to multiple late-stage clinical assets, including IL17 monoclonal antibody expected to commercialize in 2025 [6] Summary by Sections Financial Forecasts - Projected operating revenue (in million yuan): 7,836 (2023A), 9,108 (2024A), 10,201 (2025E), 11,494 (2026E), 13,153 (2027E) with growth rates of 14%, 16%, 12%, 13%, and 14% respectively [2] - Expected net profit attributable to shareholders (in million yuan): 1,549 (2023A), 2,090 (2024A), 2,345 (2025E), 2,648 (2026E), 3,027 (2027E) with growth rates of -19%, 35%, 12%, 13%, and 14% respectively [2] - Earnings per share (in yuan): 0.65 (2023A), 0.87 (2024A), 0.98 (2025E), 1.10 (2026E), 1.26 (2027E) [2] Market Position and Development - The PD1×VEGF dual antibody market is validated, with significant clinical results from competitors enhancing the outlook for SSGJ707 [6] - The company’s collaboration with Pfizer is expected to accelerate clinical development in the U.S. due to Pfizer's robust clinical and commercialization capabilities [6] Valuation Metrics - Projected P/E ratios: 28.5 (2023A), 21.2 (2024A), 18.9 (2025E), 16.7 (2026E), 14.6 (2027E) [2] - Projected P/B ratios: 3.2 (2023A), 2.9 (2024A), 2.4 (2025E), 2.0 (2026E), 1.7 (2027E) [2]

Group 1: Innovation in China - China has transitioned from a follower to a leader in innovation, playing an increasingly important role in global industrial transformation [1] - According to the 2024 Global Innovation Index, China ranks 11th globally, the only middle-income economy in the top 30, improving one position from 2023 [1] - Notable advancements include the B2-W robotic dog by Yushu Technology and BYD's world record in electric vehicle charging speed, showcasing China's technological prowess [1] Group 2: Pharmaceutical Industry Developments - Recently, 3SBio signed an exclusive licensing agreement with Pfizer for the PD-1/VEGF bispecific antibody SSGJ-707, valued at over $6 billion, with a record $1.25 billion upfront payment [2] - This agreement signifies a shift for Chinese innovative pharmaceutical companies from imitation to global leadership, enhancing industry collaboration models [2] - The trend of Chinese pharmaceutical companies utilizing the License-out model for global expansion is becoming prominent, with AstraZeneca's CEO warning that Europe is losing its leading position in pharmaceutical innovation to China [2] Group 3: International Collaborations - Chinese companies are increasingly engaging in international collaborations, as seen with Bai Li Tianheng's $8.4 billion licensing deal for an ADC drug with Bristol-Myers Squibb [3] - As of 2024, China completed 94 License-out transactions in innovative drugs, totaling $51.9 billion, a 26% year-on-year increase [3] - In the first quarter of 2025, there were 41 License-out transactions amounting to $36.93 billion, setting a new historical record for the same period [3] Group 4: Global Impact of Chinese Innovation - China's large population and unique disease spectrum make it an indispensable part of global pharmaceutical innovation [4] - Pfizer's collaboration with Guardant Health for liquid biopsy testing in China exemplifies the international partnerships driving clinical development and research [4] - The ongoing international cooperation is crucial for the globalization of Chinese pharmaceutical innovation, enhancing its international influence [4] Group 5: Future Outlook - The Chinese pharmaceutical industry is moving from "scale accumulation" to "value creation," with a focus on innovation and global competitiveness [5] - Continuous improvement in innovation quality and deepening international cooperation are leading to a new round of value reassessment in the industry [5] - Investors are encouraged to focus on innovative companies with global competitiveness to capitalize on the benefits of China's pharmaceutical globalization [5]

Core Insights - The report highlights a positive shift in fiscal data, indicating an improvement in economic conditions and policy direction, with tax revenue growth returning to positive territory for the first time this year [6][9]. - The report emphasizes the recovery of domestic markets for specific companies, particularly in the medical sector, with significant growth potential in overseas markets [14][21]. Summary by Sections Total Research - Fiscal data released on May 20, 2025, shows a year-on-year tax revenue increase of 1.9% in April, marking the first month of positive growth this year [6]. - Non-tax revenue growth slowed to 1.66%, the lowest in nearly a year, indicating a significant easing of local government financial pressures [7]. - Land transfer revenue saw a 4.27% increase, the highest growth rate since 2021, suggesting a normalization in land sales [7]. Expenditure Side - General fiscal expenditure increased by 5.8% in April 2025, significantly above the planned target of 4.4% for the year, indicating strong fiscal spending [8]. - Government fund expenditures surged by 45%, the highest growth rate since 2022, reflecting a normalization of government spending [8]. Economic Recovery - The report suggests that the ongoing "wide fiscal" policy is crucial for driving economic recovery, with improvements in the business environment for enterprises [9]. - The anticipated acceleration in fiscal spending, particularly following the April 25 Politburo meeting's directives, is expected to further boost economic activity [9]. Company Insights: Mindray Medical (300760.SZ) - The company is poised for a domestic market recovery in 2025, with a projected revenue of CNY 367.26 billion in 2024, reflecting a 5.14% increase [14]. - The company plans to distribute dividends of CNY 6.79 billion and CNY 17.10 billion for 2024 and 2025, respectively, with a payout ratio of 6% and 65% [14]. - The overseas market is performing well, with the in-vitro diagnostics (IVD) segment showing a revenue increase of 10.82% [15]. Company Insights: Lifesun Pharmaceutical (002393.SZ) - The company received over CNY 300 million in dividends from its subsidiary, enhancing its financial position [18]. - Lifesun's revenue for 2024 is projected at CNY 13.36 billion, a 15.88% year-on-year increase, despite a decline in net profit due to adjustments in its marketing strategy [20]. - The company is focusing on a dual strategy of industrial operations and capital management to drive growth [20]. Company Insights: 3SBio (01530.HK) - The company has signed an agreement with Pfizer for the global development and commercialization of its PD-1/VEGF dual-specific antibody, SSGJ-707, which could yield up to USD 60.5 billion in milestone payments [21]. - SSGJ-707 has shown promising results in clinical trials, with plans for further studies in various cancer treatments [22]. - The company maintains a strong growth outlook, with projected net profits of CNY 23.28 billion, CNY 26.12 billion, and CNY 29.38 billion for 2025-2027 [21].

| 代码 | 简称 | 类型 | 成交金额（万港元） | 成交净买入（万港元） | 日涨跌幅（%） | | --- | --- | --- | --- | --- | --- | | 01810 | 小米集团-W | 港股通(沪) | 527581.87 | -2774.41 | -2.30 | | 09988 | 阿里巴巴-W | 港股通(沪) | 341536.11 | -21884.80 | -3.25 | | 01810 | 小米集团-W | 港股通(深) | 245103.00 | -8065.59 | -2.30 | | 00939 | 建设银行 | 港股通(沪) | 212901.98 | 92936.52 | 0.00 | | 00700 | 腾讯控股 | 港股通(沪) | 209258.24 | -46369.82 | -0.77 | | 09868 | 小鹏汽车-W | 港股通(沪) | 205365.78 | -38884.85 | 5.80 | | 09988 | 阿里巴巴-W | 港股通(深) | 158991.00 | -6766.76 | -3.25 | | 03690 | 美团 ...

Investment Rating - The investment rating for the company is "Buy" (maintained) [1] Core Views - The company has authorized Pfizer for the global development, production, and commercialization rights of SSGJ-707 outside of mainland China, receiving a non-refundable upfront payment of $1.25 billion, the largest in China's BD history. The agreement also includes potential milestone payments of up to $4.8 billion and a double-digit percentage sales share based on product sales in authorized regions [7] - The company is expected to achieve a peak sales value of $8.5 billion for SSGJ-707, contributing approximately 35 billion RMB to market value based on a 20x PE after discounting. The domestic peak sales are projected at 5 billion RMB, contributing around 15 billion RMB to market value. The existing business is expected to generate over 2 billion RMB in profit, corresponding to a market value of 30 billion RMB [7] - The company has raised its net profit forecasts for 2025-2026 from 2.63 billion RMB and 2.87 billion RMB to 9.91 billion RMB and 4.47 billion RMB, respectively, with an expected net profit of 5.17 billion RMB in 2027 [7] Financial Projections - Total revenue projections for the company are as follows: - 2023A: 7,836 million RMB - 2024A: 9,108 million RMB (up 16.24% YoY) - 2025E: 19,229 million RMB (up 111.13% YoY) - 2026E: 13,174 million RMB (down 31.49% YoY) - 2027E: 14,885 million RMB (up 12.98% YoY) [1] - Net profit projections are as follows: - 2023A: 1,549 million RMB - 2024A: 2,090 million RMB (up 34.93% YoY) - 2025E: 9,908 million RMB (up 373.98% YoY) - 2026E: 4,474 million RMB (down 54.85% YoY) - 2027E: 5,169 million RMB (up 15.54% YoY) [1] - The latest diluted EPS projections are: - 2023A: 0.65 RMB - 2024A: 0.87 RMB - 2025E: 4.13 RMB - 2026E: 1.87 RMB - 2027E: 2.15 RMB [1]

智通财经APP获悉，5月22日港股市场，北水成交净买入38.8亿港元，其中港股通(沪)成交净买入30.24亿 港元，港股通(深)成交净买入8.56亿港元。 北水净买入最多的个股是建设银行(00939)、美团-W(03690)、泡泡玛特(09992)。北水净卖出最多的个股 是腾讯(00700)、小鹏汽车-W(09868)、阿里巴巴-W(09988)。 | 股票名称 | 买入额 | 卖出额 | 买卖总额 | | --- | --- | --- | --- | | | | | 净流入 | | 小米集团-W | | | 52.76亿 | | HK 01810 | 26.24 乙 | 26.52亿 | -2774.41万 | | 阿里巴巴-W | 15.98 乙 | 18.17 乙 | 34.15亿 | | HK 09988 | | | -2.19 Z- | | 建设银行 | 15.29 乙 | 6.00亿 | 21.29亿 | | HK 00939 | | | +9.29 乙 | | 腾讯控股 | 8.14 Z | 12.78 乙 | 20.93亿 | | HK 00700 | | | -4.64 Z | | 小鹏汽 ...

Investment Rating - The report maintains a "Recommended" rating for the company [5][7]. Core Insights - The company has signed an agreement with Pfizer to exclusively grant rights for its innovative PD-1/VEGF bispecific antibody SSGJ-707, receiving an upfront payment of $1.25 billion and potential milestone payments up to $4.8 billion [3][4]. - SSGJ-707 shows best-in-class potential with promising clinical data in treating non-small cell lung cancer (NSCLC) and has received breakthrough therapy designation from the National Medical Products Administration [4]. - The company has a robust pipeline with 30 products in development, several of which are nearing market application, indicating a fruitful period ahead for its innovation pipeline [4]. Financial Projections - The company expects total revenue of RMB 182.44 billion, RMB 127.52 billion, and RMB 147.31 billion for the years 2025, 2026, and 2027 respectively, with corresponding net profits of RMB 85.75 billion, RMB 34.13 billion, and RMB 41.02 billion [5][6]. - Earnings per share (EPS) are projected to be RMB 3.57, RMB 1.42, and RMB 1.71 for the years 2025, 2026, and 2027 respectively [6][9]. Business Development - The company is expanding its commercial footprint through partnerships, having secured four collaborations in 2024, which will enhance its product portfolio and revenue growth [5][4]. - Core products are expected to continue stable growth in 2024, with ongoing expansion into new indications and formulations [5].

Investment Rating - The report maintains a "Recommended" rating for the company [5][7]. Core Insights - The company has signed an agreement with Pfizer to exclusively grant rights for its innovative PD-1/VEGF bispecific antibody SSGJ-707, receiving an upfront payment of $1.25 billion and potential milestone payments up to $4.8 billion [3][4]. - SSGJ-707 shows best-in-class potential with promising clinical data in non-small cell lung cancer (NSCLC), having received breakthrough therapy designation from the National Medical Products Administration [4]. - The company has a robust pipeline with 30 products in development, several of which are nearing market application, indicating a fruitful period ahead for innovation [4]. Financial Projections - The company expects total revenue of RMB 182.44 billion, RMB 127.52 billion, and RMB 147.31 billion for the years 2025, 2026, and 2027 respectively, with corresponding net profits of RMB 85.75 billion, RMB 34.13 billion, and RMB 41.02 billion [5][6]. - Earnings per share (EPS) are projected to be RMB 3.57, RMB 1.42, and RMB 1.71 for the years 2025, 2026, and 2027 respectively [6][9]. Business Development - The company is expanding its commercial footprint through collaborations, having secured four partnerships in 2024, which will enhance its product portfolio and revenue growth [5][4]. - Core products are expected to continue stable growth in 2024, with ongoing expansion into new indications and formulations [5].

Investment Rating - The investment rating for the company is "Buy" (maintained) [1] Core Views - The company has entered into a significant agreement with Pfizer regarding the global development, production, and commercialization rights for its innovative PD-1/VEGF bispecific antibody SSGJ-707, which includes an upfront payment of $1.25 billion and potential milestone payments of up to $4.8 billion [6] - The company maintains its profit forecast, expecting net profits of 2.328 billion, 2.612 billion, and 2.938 billion CNY for the years 2025, 2026, and 2027 respectively, with corresponding EPS of 0.97, 1.09, and 1.23 CNY per share [6] - The current stock price corresponds to a PE ratio of 9.3, 8.3, and 7.4 for the years 2025, 2026, and 2027 respectively, indicating a favorable valuation [6] Financial Summary and Valuation Indicators - The company's revenue is projected to grow from 7.836 billion CNY in 2023 to 10.078 billion CNY in 2025, reflecting a year-over-year growth rate of 14.1% and 10.7% respectively [9] - Net profit is expected to increase from 1.549 billion CNY in 2023 to 2.328 billion CNY in 2025, with a year-over-year growth of (19.1%) in 2023, followed by 34.9% in 2024 and 11.4% in 2025 [9] - The gross margin is projected to remain stable at around 84.2% from 2025 to 2027, while the net margin is expected to improve slightly from 26.6% in 2025 to 26.8% in 2027 [9] - The company’s ROE is forecasted to increase from 0.8% in 2025 to 1.1% in 2027 [9] Pipeline and Product Development - The company’s core product SSGJ-707 has shown promising results in clinical trials for NSCLC, achieving excellent ORR and DCR, and has received breakthrough therapy designation from the National Medical Products Administration [7] - The company is advancing multiple clinical studies for SSGJ-707, including a Phase III trial for NSCLC and ongoing research for colorectal cancer and gynecological tumors [7] - The company’s existing products, including Tebentafusp and others, are expected to contribute positively to cash flow, with successful negotiations for new indications enhancing growth potential [7]

Group 1 - The core point of the news is that Sangfor Pharmaceuticals has entered into a significant agreement with Pfizer, granting global rights for its PD-1/VEGF dual antibody outside of China, along with commercialization options in China [1] - Sangfor Pharmaceuticals will receive an upfront payment of $1.25 billion, potential milestone payments of up to $4.8 billion, and a double-digit percentage sales share [1] - The deal's record-breaking financial terms and timing exceed market expectations, potentially enhancing overseas peak sales forecasts and providing substantial valuation flexibility [1] Group 2 - Key products such as Tebiou and Mandi are experiencing rapid growth, which is expected to support the company's stable growth in the future [2] - Tebiou's sales are projected to reach 5.06 billion yuan in 2024, reflecting a year-on-year growth of 20.4% and a market share of 34.3% [2] - Mandi's sales are expected to reach 1.34 billion yuan in 2024, with a year-on-year increase of 18.9%, particularly showing strong recovery in the second half of 2024 [2] Group 3 - Profit forecasts indicate that the company will recognize the $1.25 billion upfront payment in 2025, with projected net profits of 9.788 billion, 2.988 billion, and 3.472 billion yuan for the next three years, showing year-on-year growth rates of 368.2%, -69.5%, and 16.2% respectively [3] - The adjusted net profit for 2025 is expected to reach 2.3 billion yuan, with a reasonable valuation of approximately 23 billion yuan based on a 10x PE ratio [3] - The overall target market capitalization for the company is set at 59.5 billion yuan, approximately 64.5 billion Hong Kong dollars, reflecting the stable growth of its core business and the high elasticity provided by innovative products like the PD-1/VEGF dual antibody [3]